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公开(公告)号:US20050147643A1
公开(公告)日:2005-07-07
申请号:US11006893
申请日:2004-12-07
申请人: William Hunter , David Gravett , Philip Toleikis , Arpita Maiti , Pierre Signore , Richard Liggins
发明人: William Hunter , David Gravett , Philip Toleikis , Arpita Maiti , Pierre Signore , Richard Liggins
IPC分类号: A61B17/11 , A61B17/12 , A61B17/68 , A61C5/00 , A61F2/00 , A61F2/28 , A61F13/00 , A61K31/045 , A61K31/4745 , A61K31/513 , A61K31/525 , A61K31/65 , A61K31/70 , A61K31/7012 , A61K31/704 , A61K31/7048 , A61K31/7072 , A61K31/765 , A61K33/14 , A61K33/24 , A61K38/17 , A61K38/18 , A61K38/19 , A61K38/20 , A61K38/24 , A61K38/39 , A61K38/48 , A61K49/00 , A61L27/00 , A61L27/54 , A61L31/00 , A61L31/16
CPC分类号: A61L27/54 , A61B17/11 , A61B17/12022 , A61B17/12099 , A61B17/12109 , A61B17/1214 , A61B17/12168 , A61B17/12186 , A61B17/1219 , A61B17/68 , A61F2250/0067 , A61K38/363 , A61K38/38 , A61K38/39 , A61K38/4833 , A61K45/06 , A61L31/16 , A61L2300/00 , A61L2300/412 , A61L2430/38 , A61K2300/00
摘要: Implants are used in combination with a fibrosis-inducing agent in order to induce fibrosis that may otherwise not occur when the implant is placed within an animal or increase fibrosis between the implant and the host tissue.
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公开(公告)号:US20080009902A1
公开(公告)日:2008-01-10
申请号:US11669097
申请日:2007-01-30
申请人: William Hunter , Rui Avelar , David Gravett , Philip Toleikis , Arpita Maiti
发明人: William Hunter , Rui Avelar , David Gravett , Philip Toleikis , Arpita Maiti
IPC分类号: A61B17/04
CPC分类号: A61L17/005 , A61K9/0024 , A61K47/32 , A61K47/34 , A61K47/36 , A61K47/42 , A61L31/16 , A61L2300/30 , A61L2300/40 , A61L2300/45 , Y10T29/49826
摘要: Sutures are used in combination with fibrosing agents to induce or stimulate fibrosis that between the sutures and the host tissues into which the sutures are inserted. Compositions and methods are described for use in lifting tissue, closing wound, and other applications.
摘要翻译: 缝线与纤维化剂组合使用以诱导或刺激缝合线和插入缝线的主体组织之间的纤维化。 描述组合物和方法用于提升组织,闭合伤口和其它应用。
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公开(公告)号:US20060147492A1
公开(公告)日:2006-07-06
申请号:US11343809
申请日:2006-01-31
申请人: William Hunter , David Gravett , Philip Toleikis , Arpita Maiti , Pierre Signore , Richard Liggins
发明人: William Hunter , David Gravett , Philip Toleikis , Arpita Maiti , Pierre Signore , Richard Liggins
CPC分类号: A61L31/16 , A61B17/11 , A61B17/12022 , A61B17/1219 , A61F2250/0067 , A61L2300/404 , A61L2300/406 , A61L2300/416 , A61L2300/426 , A61L2300/432 , A61N1/05
摘要: Implants are used in combination with an anti-scarring agent in order to inhibit scarring that may otherwise occur when the implant is placed within an animal. The agent may be any suitable anti-scarring agent, e.g., a cell cycle inhibitor, and may be used in conjunction with a second pharmaceutical agent, e.g., an antibiotic. Suitable implants include intravascular implants, a vascular graft or wrap implant, an implant for hemodialysis access, an implant that provides an anastomotic connection, ventricular assist implant, a prosthetic heart valve implant, an inferior vena cava filter implant, a peritoneal dialysis catheter implant, a central nervous system shunt, an intraocular lens, an implant for glaucoma drainage, a penile implant, an endotracheal tube, a tracheostomy tube, a gastrointestinal device, and a spinal implant.
摘要翻译: 植入物与抗瘢痕形成剂组合使用以抑制当植入物置于动物体内时可能发生的瘢痕形成。 该试剂可以是任何合适的抗瘢痕形成剂,例如细胞周期抑制剂,并且可以与第二药剂如抗生素联合使用。 合适的植入物包括血管内植入物,血管移植物或包裹植入物,用于血液透析通路的植入物,提供吻合连接的植入物,心室辅助植入物,假体心脏瓣膜植入物,下腔静脉滤器植入物,腹膜透析导管植入物, 中枢神经系统分流器,眼内透镜,用于青光眼引流的植入物,阴茎植入物,气管内导管,气管造口管,胃肠装置和脊柱植入物。
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公开(公告)号:US20050208095A1
公开(公告)日:2005-09-22
申请号:US10996354
申请日:2004-11-22
申请人: William Hunter , Philip Toleikis , David Gravett , Arpita Maiti , Richard Liggins , Aniko Takacs-Cox , Rui Avelar , Troy Loss
发明人: William Hunter , Philip Toleikis , David Gravett , Arpita Maiti , Richard Liggins , Aniko Takacs-Cox , Rui Avelar , Troy Loss
IPC分类号: A61B19/00 , A61F2/00 , A61F2/08 , A61F2/28 , A61F2/44 , A61K9/14 , A61K31/337 , A61K31/365 , A61K31/4745 , A61K31/704 , A61K31/7048 , A61K31/7072 , A61K38/00 , A61L27/54 , A61L31/16 , A61M31/00 , A61N1/00 , A61N1/05
CPC分类号: A61K45/06 , A61L27/54 , A61L31/16 , A61L2300/404 , A61L2300/416 , A61L2300/432
摘要: Compositions comprising anti-fibrotic agent(s) and/or polymeric compositions can be used in various medical applications including the prevention of surgical adhesions, treatment of inflammatory arthritis, treatment of scars and keloids, the treatment of vascular disease, and the prevention of cartilage loss.
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公开(公告)号:US20050186246A1
公开(公告)日:2005-08-25
申请号:US11006883
申请日:2004-12-07
申请人: William Hunter , David Gravett , Philip Toleikis , Arpita Maiti
发明人: William Hunter , David Gravett , Philip Toleikis , Arpita Maiti
IPC分类号: A61B5/00 , A61F2/00 , A61F2/02 , A61F2/12 , A61F2/28 , A61F13/00 , A61K9/22 , A61K38/17 , A61L27/00 , A61L27/54 , A61L31/00 , A61L31/16 , A61M31/00 , A61N1/00 , A61N1/05 , A61N1/18 , A61N1/36 , A61N1/372 , A61N1/375
CPC分类号: A61N1/05 , A61K38/17 , A61L27/3641 , A61L27/54 , A61L31/16 , A61L2300/404 , A61L2300/416 , A61L2300/432 , A61L2300/45 , A61N1/36 , A61N1/372
摘要: Soft tissue implants (e.g., breast, pectoral, chin, facial, lip, and nasal implants) are used in combination with an anti-scarring agent in order to inhibit scarring that may otherwise occur when the implant is placed within an animal.
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公开(公告)号:US20050186244A1
公开(公告)日:2005-08-25
申请号:US11001790
申请日:2004-12-02
申请人: William Hunter , Philip Toleikis , David Gravett , Arpita Maiti , Richard Liggins , Aniko Takacs-Cox , Rui Avelar , Troy Loss
发明人: William Hunter , Philip Toleikis , David Gravett , Arpita Maiti , Richard Liggins , Aniko Takacs-Cox , Rui Avelar , Troy Loss
IPC分类号: A61B19/00 , A61F2/00 , A61F2/08 , A61F2/28 , A61F2/44 , A61K9/14 , A61K31/337 , A61K31/365 , A61K31/4745 , A61K31/704 , A61K31/7048 , A61K31/7072 , A61K38/00 , A61L27/54 , A61L31/16 , A61M31/00 , A61N1/00 , A61N1/05
CPC分类号: A61K45/06 , A61L27/54 , A61L31/16 , A61L2300/404 , A61L2300/416 , A61L2300/432
摘要: Compositions comprising anti-fibrotic agent(s) and/or polymeric compositions can be used in various medical applications including the prevention of surgical adhesions, treatment of inflammatory arthritis, treatment of scars and keloids, the treatment of vascular disease, and the prevention of cartilage loss.
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公开(公告)号:US20050186242A1
公开(公告)日:2005-08-25
申请号:US10999204
申请日:2004-11-29
申请人: William Hunter , David Gravett , Philip Toleikis , Arpita Maiti , Pierre Signore , Richard Liggins , Dechi Guan
发明人: William Hunter , David Gravett , Philip Toleikis , Arpita Maiti , Pierre Signore , Richard Liggins , Dechi Guan
IPC分类号: A61B17/00 , A61B17/11 , A61B17/12 , A61F2/00 , A61F2/86 , A61F13/00 , A61K38/48 , A61L27/00 , A61L27/54 , A61L31/00 , A61L31/16 , A61M29/00 , A61M31/00
CPC分类号: A61B17/12172 , A61B17/00491 , A61B17/11 , A61B17/12022 , A61B17/12045 , A61B17/12136 , A61B17/1215 , A61B17/12177 , A61B17/12186 , A61B17/1219 , A61B2017/00004 , A61F2/86 , A61F2250/0067 , A61L31/16 , A61L2300/412
摘要: Intravascular devices (e.g., stents, stent grafts, covered stents, aneurysm coils, embolic agents and drug delivery catheters and balloons) are used in combination with fibrosing agents in order to induce fibrosis that may otherwise not occur when the implant is placed within an animal or to promote fibrosis betweent the devices and the host tissues. Compositions and methods are described for use in the treatment of aneurysms and unstable arterial (vulnerable) plaque.
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公开(公告)号:US20050182496A1
公开(公告)日:2005-08-18
申请号:US11006906
申请日:2004-12-07
申请人: William Hunter , David Gravett , Philip Toleikis , Arpita Maiti
发明人: William Hunter , David Gravett , Philip Toleikis , Arpita Maiti
IPC分类号: A61B5/00 , A61F2/00 , A61F2/02 , A61F2/12 , A61F2/28 , A61F13/00 , A61K9/22 , A61K38/17 , A61L27/00 , A61L27/54 , A61L31/00 , A61L31/16 , A61M31/00 , A61N1/00 , A61N1/05 , A61N1/18 , A61N1/36 , A61N1/372 , A61N1/375
CPC分类号: A61N1/05 , A61K38/17 , A61L27/3641 , A61L27/54 , A61L31/16 , A61L2300/404 , A61L2300/416 , A61L2300/432 , A61L2300/45 , A61N1/36 , A61N1/372
摘要: Soft tissue implants (e.g., breast, pectoral, chin, facial, lip, and nasal implants) are used in combination with an anti-scarring agent in order to inhibit scarring that may otherwise occur when the implant is placed within an animal.
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公开(公告)号:US20050182463A1
公开(公告)日:2005-08-18
申请号:US11001788
申请日:2004-12-02
申请人: William Hunter , Philip Toleikis , David Gravett , Arpita Maiti , Richard Liggins , Aniko Takacs-Cox , Rui Avelar , Troy Loss
发明人: William Hunter , Philip Toleikis , David Gravett , Arpita Maiti , Richard Liggins , Aniko Takacs-Cox , Rui Avelar , Troy Loss
IPC分类号: A61B19/00 , A61F2/00 , A61F2/08 , A61F2/28 , A61F2/44 , A61K9/14 , A61K31/337 , A61K31/365 , A61K31/4745 , A61K31/704 , A61K31/7048 , A61K31/7072 , A61K38/00 , A61L27/54 , A61L31/16 , A61M31/00 , A61N1/00 , A61N1/05
CPC分类号: A61K45/06 , A61L27/54 , A61L31/16 , A61L2300/404 , A61L2300/416 , A61L2300/432
摘要: Compositions comprising anti-fibrotic agent(s) and/or polymeric compositions can be used in various medical applications including the prevention of surgical adhesions, treatment of inflammatory arthritis, treatment of scars and keloids, the treatment of vascular disease, and the prevention of cartilage loss.
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公开(公告)号:US20050175664A1
公开(公告)日:2005-08-11
申请号:US11004672
申请日:2004-12-02
申请人: William Hunter , David Gravett , Philip Toleikis , Arpita Maiti
发明人: William Hunter , David Gravett , Philip Toleikis , Arpita Maiti
IPC分类号: A61B5/00 , A61F2/00 , A61F2/02 , A61F2/12 , A61F2/28 , A61F13/00 , A61K9/22 , A61K38/17 , A61L27/00 , A61L27/54 , A61L31/00 , A61L31/16 , A61M31/00 , A61N1/00 , A61N1/05 , A61N1/18 , A61N1/36 , A61N1/372 , A61N1/375
CPC分类号: A61N1/05 , A61K38/17 , A61L27/3641 , A61L27/54 , A61L31/16 , A61L2300/404 , A61L2300/416 , A61L2300/432 , A61L2300/45 , A61N1/36 , A61N1/372
摘要: Pumps and sensors for contact with tissue are used in combination with an anti-scarring agent (e.g., a cell cycle inhibitor) in order to inhibit scarring that may otherwise occur when the pumps and sensors are implanted within an animal.
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