公开(公告)号：US07025724B2

公开(公告)日：2006-04-11

申请号：US10275806

申请日：2001-04-27

Applicant: Dan Adam ,  Oleg Michailovich

Inventor： Dan Adam ,  Oleg Michailovich

IPC: A61B8/00

CPC classification number: G01S7/52077 ,  A61B8/08 ,  A61B8/587 ,  G01S15/8977 ,  G06K9/00516 ,  G06T5/003 ,  G06T2207/10132 ,  G06T2207/30004

Abstract: Methods and associated apparatuses for imaging a target. An echo sequence image of the target is acquired and a log spectrum of at least a portion of the echo sequence image is computed. A point spread function is estimated by one of two methods. According to the first method, a low-resolution wavelet projection of the echo sequence log spectrum is used as an estimate of the log spectrum of the point spread function. According to the second method, an outlier-resistant wavelet transform of the echo sequence log spectrum is effected, followed by soft-thresholding and an inverse wavelet transform. Under both methods, a frequency domain phase of the point spread function also is estimated, the relevant portion of the echo sequence image is deconvolved using the estimated point spread function.

Abstract translation: 用于对目标进行成像的方法和相关设备。 获取目标的回波序列图像，并计算回波序列图像的至少一部分的对数谱。 点扩散函数由两种方法之一估计。 根据第一种方法，使用回波序列对数谱的低分辨率小波投影作为点扩散函数的对数谱的估计。 根据第二种方法，对回波序列对数谱的异常小波变换进行软阈值和逆小波变换。 在两种方法下，估计点扩散函数的频域相位，使用估计的点扩散函数对回波序列图像的相关部分进行去卷积。

公开(公告)号：US20050255101A1

公开(公告)日：2005-11-17

申请号：US10073301

申请日：2002-02-13

Applicant: Yoram Reiter ,  Galit Denkberg

Inventor： Yoram Reiter ,  Galit Denkberg

IPC: G01N33/53 ,  A61K39/395 ,  A61K47/48 ,  A61P31/12 ,  A61P37/02 ,  C07K7/06 ,  C07K16/18 ,  C07K16/28 ,  C12N15/09 ,  C12P21/02 ,  C12P21/08 ,  C12Q1/02 ,  G01N33/569 ,  G01N33/574 ,  C07K16/30

CPC classification number: C07K16/2833 ,  A61K47/6849 ,  A61K2039/505 ,  C07K2317/34 ,  C07K2317/622 ,  C07K2319/00

Abstract: An isolated molecule which comprises an antibody specifically bindable with a binding affinity below 20 nanomolar, preferably below 10 nanomolar, to a human major histocompatibility complex (MHC) class I being complexed with a HLA-restricted antigen and optionally further comprises an identifiable or therapeutic moiety conjugated to the antibody.

Abstract translation: 一种分离的分子，其包含与HLA限制性抗原复合的人类主要组织相容性复合物（MHC）I类具有低于20纳摩尔，优选低于10纳摩尔的结合亲和力特异性结合的抗体，并且任选地还包含可识别或治疗性部分 与抗体缀合。

公开(公告)号：US20050171210A1

公开(公告)日：2005-08-04

申请号：US10952367

申请日：2004-09-29

Applicant: Moussa Youdim ,  Ofer Binah ,  Zaid Abassi ,  Yaron Barac

Inventor： Moussa Youdim ,  Ofer Binah ,  Zaid Abassi ,  Yaron Barac

IPC: A61K31/13 ,  A61K31/135 ,  A61K31/205 ,  A61K31/27

CPC classification number: A61K31/136 ,  A61K31/13

Abstract: Propargylamine, propargylamine derivatives including N-propargyl-1-aminoindan and analogs thereof, and pharmaceutically acceptable salts thereof, are useful for prevention or treatment of cardiovascular disorders and diseases.

Abstract translation: 炔丙胺，包括N-炔丙基-1-氨基茚丹及其类似物的炔丙胺衍生物及其药学上可接受的盐可用于预防或治疗心血管疾病和疾病。

公开(公告)号：US20050132837A1

公开(公告)日：2005-06-23

申请号：US10991644

申请日：2004-11-18

Applicant: Ronen Ben Horin ,  Moshe Shoham ,  Hagay Bamberger

Inventor： Ronen Ben Horin ,  Moshe Shoham ,  Hagay Bamberger

IPC: B25J7/00 ,  B25J17/02 ,  B25J17/00

CPC classification number: B25J17/0266 ,  B25J7/00 ,  B25J9/0015 ,  Y10T74/20305 ,  Y10T74/20329

Abstract: The invention relates to a mechanical structure which provides motion in six degrees of freedom, which comprises: (a) a main plate; (b) a base; (c) at least three supporting structures, each comprising a lower, bridge-like section supported by the base, and an upper section connected to said bridge section and to said main plate, wherein: (I) said bridge-like structure comprising two supporting plates, two intermediate plates, and one middle plate, all being serially connected one to another by means of four transversal hinges; (II) each pair of said supporting plates being slidable in linear displacement parallel to the base; (III) said upper section comprising two plates, a lower plate connected to said middle plate by means of a hinge transversal to said lower plate but longitudinal with respect to said middle plate, and an upper plate connected to said lower plate by means of a longitudinal hinge and to said main plate by means of a transversal hinge; (d) At least six linear motors connected each to a corresponding supporting plate, for applying a force thereon in order to effect a linear displacement of said plate; and (e) control means for determining the linear displacement of each linear motor.

Abstract translation: 本发明涉及提供六自由度运动的机械结构，其包括：（a）主板; （b）基地; （c）至少三个支撑结构，每个支撑结构包括由基座支撑的下部桥状部分，以及连接到所述桥接部分和所述主板的上部部分，其中：（I）所述桥状结构包括两个 支撑板，两个中间板和一个中间板，均通过四个横向铰链彼此串联连接; （II）每对所述支撑板可平行于所述底座的线性位移滑动; （III），所述上部部分包括两个板，下板通过横向于所述下板的铰链而相对于所述中间板纵向连接到所述中间板，并且上板通过连接到所述下板的上板 纵向铰链，并通过横向铰链连接到所述主板; （d）至少六根线性电动机，每个至少连接到相应的支撑板上，用于在其上施加力以便实现所述板的线性位移; 和（e）用于确定每个线性电动机的线性位移的控制装置。

公开(公告)号：US20030138987A1

公开(公告)日：2003-07-24

申请号：US10051069

申请日：2002-01-22

Applicant: TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD.

Inventor： Yael Nemirovsky ,  Raoul Weil ,  Robert Beserman ,  Joseph Shamir ,  Sara Stolyarova ,  Arye Peyser

IPC: H01L021/00

CPC classification number: H01L31/085 ,  H01L31/186 ,  Y02E10/50 ,  Y02P70/521

Abstract: A method for improving CdZnTe-based gamma-ray detectors is presented. A CdZnTe detector/crystal is exposed to acoustic waves. After exposure to acoustic waves, the CdZnTe gamma-detector gains higher resistivity and exhibits better spectral resolution and greater sensitivity. Further, when a batch of detectors is made according to the method of the present invention, the properties of the crystals are more homogenous, allowing for cheaper and more standardized detectors.

Abstract translation: 提出了一种改进基于CdZnTe的γ射线探测器的方法。 CdZnTe探测器/晶体暴露于声波。 在暴露于声波之后，CdZnTe伽马检测器获得更高的电阻率，并表现出更好的光谱分辨率和更高的灵敏度。 此外，当根据本发明的方法制造一批检测器时，晶体的性质更均匀，允许更廉价和更标准化的检测器。

公开(公告)号：US20030114410A1

公开(公告)日：2003-06-19

申请号：US10305348

申请日：2002-11-27

Applicant: Technion Research And Development Foundation Ltd.

Inventor： Gera Neufeld ,  Gal Akiri ,  Zahava Vadasz ,  Stela Gengrinovitch

IPC: A61K048/00 ,  A61K039/395

CPC classification number: C12Q1/6886 ,  A61K38/00 ,  A61K2039/505 ,  C07K16/30 ,  C07K16/40 ,  C12N9/0022 ,  C12Q1/26 ,  C12Y104/03013 ,  G01N33/574 ,  G01N33/57419 ,  G01N2500/00

Abstract: Methods and compositions suitable for modulating angiogenesis in a mammalian tissue are provided. Further provided are methods suitable for inhibiting metastasis and fibrosis in a mammalian tissue.

Abstract translation: 提供适于调节哺乳动物组织中血管生成的方法和组合物。 还提供了适合于抑制哺乳动物组织中的转移和纤维化的方法。

公开(公告)号：US20030028360A1

公开(公告)日：2003-02-06

申请号：US10160404

申请日：2002-06-04

Applicant: TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD.

Inventor： Ofir Bochobza-Degani ,  David Elata ,  Yael Nemirovsky ,  Eran Socher

IPC: G06F017/10

CPC classification number: B81C99/006 ,  H02N1/006

Abstract: A method of efficiently extracting the pull-in parameters of an electrostatically activated actuator. The actuator is modeled as an elastic element. For each of a plurality of deformations of the elastic element, a corresponding voltage is calculated. The highest such voltage is the pull-in voltage of the actuator. The corresponding deformation is the pull-in deformation of the actuator. Each deformation is defined by fixing a displacement of one degree of freedom of the elastic body and calculating corresponding equilibrium displacements of all the other degrees of freedom without the application of any external mechanical forces to ensure equilibrium. The actuator is altered to optimize whichever pull-in parameter is relevant to the desired application of the actuator.

Abstract translation: 一种有效提取静电激活致动器的拉入参数的方法。 致动器被建模为弹性元件。 对于弹性元件的多个变形中的每一个，计算相应的电压。 最高的这种电压是执行器的引入电压。 相应的变形是致动器的拉入变形。 通过固定弹性体的一个自由度的位移并计算所有其他自由度的相应的平衡位移来定义每个变形，而不必施加任何外部机械力来确保平衡。 致动器被改变以优化与执行器的期望应用相关的哪个拉入参数。

公开(公告)号：US5807403A

公开(公告)日：1998-09-15

申请号：US622598

申请日：1996-03-26

Applicant: Mordechai Beyar ,  Amnon Foux

Inventor： Mordechai Beyar ,  Amnon Foux

IPC: A61B17/00 ,  A61B17/04

CPC classification number: A61B17/0401 ,  A61B17/0482 ,  A61B2017/00535 ,  A61B2017/00805 ,  A61B2017/0409 ,  A61B2017/0414 ,  A61B2017/0454

Abstract: A medical anchor device for implantation into a bone of a patient includes a staple having a leading, bone-boring tip for self-tapping a hole, a trailing, driven end for receiving implanting force to self-tap and implant said staple into the bone of a patient, and an attached suture thread. The staple has a longitudinal axis which passes through the tip and the driven end, the longitudinal axis changing shape upon implantation of the staple into a bone. A method of treating a patient includes ejecting and implanting the staple comprising a suture thread secured thereto into a bone by self-tapping a hole in the bone and securing the suture thread to a portion of the body's anatomy.

Abstract translation: 用于植入患者骨骼的医疗锚定装置包括具有用于自攻孔的前导骨头尖端的钉，用于接收植入力以自动敲入并将所述钉植入到骨中的拖尾驱动端 的患者和附着的缝合线。 订书钉具有穿过尖端和从动端的纵向轴线，当将钉子植入骨骼时，纵向轴线改变形状。 一种治疗患者的方法包括通过自攻开骨中的孔并且将缝合线固定到身体的解剖结构的一部分，将包括固定在其上的缝合线的钉子弹出并植入到骨中。

公开(公告)号：US5689422A

公开(公告)日：1997-11-18

申请号：US423359

申请日：1995-04-18

Applicant: Michael Heymann ,  Arie Feuer

Inventor： Michael Heymann ,  Arie Feuer

IPC: B60K31/00 ,  G01S13/93 ,  B60K31/04 ,  G01S13/60 ,  G08G1/16

CPC classification number: B60K31/0008 ,  G01S2013/9321 ,  G01S2013/9325 ,  G01S2013/9353

Abstract: A converter for use with a constant speed vehicle cruise control system including a speedometer for generating a self speed signal representative of the self speed of the vehicle and a speed adjustment control responsively coupled to the speedometer for maintaining the self speed of the vehicle at a preset speed. The converter adapts the control system to a constant distance system, and comprises a rangefinder for generating a distance signal corresponding to the distance of the vehicle from a front vehicle, and a distance-dependent speed adjustment device coupled to the rangefinder and to the speedometer for generating a synthetic-speed signal corresponding to the set speed required for maintaining a predetermined distance between the two vehicles. A selector switch allows either the self speed or synthetic-speed signals to be connected to the speedometer of the cruise control system.

Abstract translation: 一种与恒速车辆巡航控制系统一起使用的转换器，包括用于产生表示车辆自身速度的自速度信号的速度计，以及响应地耦合到速度计的速度调节控制器，用于将车辆的自身速度保持在预设位置 速度。 该转换器将控制系统适配于恒定距离系统，并且包括用于产生对应于车辆与前车辆的距离的距离信号的测距仪，以及耦合到测距仪和速度计的距离相关速度调节装置， 产生对应于在两个车辆之间保持预定距离所需的设定速度的合成速度信号。 选择开关允许将自速或合成速度信号连接到巡航控制系统的速度计。

公开(公告)号：US5483968A

公开(公告)日：1996-01-16

申请号：US886227

申请日：1992-05-21

Applicant: Dan Adam ,  Ilia Vitsnudel ,  Shlomo Gilat ,  Samuel Sideman

Inventor： Dan Adam ,  Ilia Vitsnudel ,  Shlomo Gilat ,  Samuel Sideman

IPC: A61B5/0408 ,  A61B5/0432

CPC classification number: A61B5/6805 ,  A61B5/04085 ,  A61B5/7232

Abstract: A method and apparatus for analyzing the electrical activity of the heart by Body Surface Potential Mapping (BSMP) in which an array of electrodes are applied over the thoracic region of a subject's body for producing measurements of the electrical signals generated in the thoracic region, and the measurements are processed for indicating certain electrical events in the subject's body. The array of electrodes are utilized to measure only the times of crossing of the electrical signals over a preset threshold.

Abstract translation: 一种用于通过身体表面电位映射（BSMP）分析心脏的电活动的方法和装置，其中将电极阵列施加在受试者身体的胸部区域上，以产生在胸部区域中产生的电信号的测量值，以及 处理测量结果以指示受检者身体中的某些电气事件。 电极阵列仅用于测量电信号在预设阈值上的交叉次数。