公开(公告)号：USPP30853P2

公开(公告)日：2019-08-27

申请号：US15932407

申请日：2018-02-26

申请人： University of Georgia Research Foundation, Inc.

发明人： John M. Ruter

IPC分类号： A01H5/00 ,  A01H6/60

摘要： A new Hibiscus plant named ‘RutHib2’ is characterized by a combination of good form, medium vigor, purple foliage, magenta flowers with a red eye, and good tolerance to Alternaria, Cercospora, and Phytophthora pathogens.

公开(公告)号：USPP30816P3

公开(公告)日：2019-08-20

申请号：US15732208

申请日：2017-10-03

申请人： University of Georgia Research Foundation, Inc.

发明人： Wayne W. Hanna ,  Brian M. Schwartz

IPC分类号： A01H5/08 ,  A01H6/78

摘要： A new variety of Citrus reticulata plant named ‘Tift3-46’ produces fruit with a reduced number of seeds, making it valuable as a backyard fruit tree. Also, it is a desirable tree for landscaping.

公开(公告)号：US10328182B2

公开(公告)日：2019-06-25

申请号：US14942139

申请日：2015-11-16

申请人： University of Georgia Research Foundation, Inc.

发明人： Shiyou Chen ,  Rui Tang

IPC分类号： A61K48/00 ,  C07H21/02 ,  C07H21/04 ,  A61L31/16 ,  A61L27/54 ,  A61K45/06 ,  A61K31/00 ,  A61K31/198 ,  A61K31/42 ,  A61K31/7068 ,  A61K31/7072 ,  C12N15/113 ,  A61L27/50 ,  A61K35/74 ,  A61K31/4412 ,  A61L31/08

摘要： Compositions, devices, grafts and methods for reducing or preventing anti-neointima following cardiovascular injuries and interventions are disclosed. The compositions, devices, and grafts typically include an effective amount of a CTP synthase 1 inhibitor to reduce proliferation of vascular smooth muscle cells, without substantial reducing the proliferation of endothelial cells. Methods of reducing neointima formation, accelerating re-endothelialization, and reducing restenosis in a subject using the compositions, devices, and grafts are also disclosed.

公开(公告)号：US10307435B2

公开(公告)日：2019-06-04

申请号：US15381877

申请日：2016-12-16

申请人： University of Georgia Research Foundation, Inc.

发明人： Jamie A. Cooper

IPC分类号： A61K31/7016 ,  A61K47/30 ,  A61K9/00 ,  A61K9/08 ,  A61K9/70 ,  A23L33/125

摘要： Disclosed are compositions, articles, and method for enhancing exercise performance in a subject. The method involves contacting the oral cavity of the subject with a composition comprising a sweet and caloric food product for a period sufficient to cause a cephalic phase response in the subject.

公开(公告)号：US20190104661P1

公开(公告)日：2019-04-04

申请号：US15732208

申请日：2017-10-03

申请人： University of Georgia Research Foundation, Inc.

发明人： Wayne W. Hanna ,  Brian M. Schwartz

IPC分类号： A01H6/78

摘要： A new variety of Citrus reticulata plant named ‘Tift3-46’ produces fruit with a reduced number of seeds, making it valuable as a backyard fruit tree. Also, it is a desirable tree for landscaping.

公开(公告)号：US10196616B2

公开(公告)日：2019-02-05

申请号：US15890575

申请日：2018-02-07

申请人： The United States of America, as represented by the Secretary of Agriculture ,  University of Georgia Research Foundation, Inc.

发明人： Claudio L. Afonso ,  Valerie C. Marcano ,  Nany Stivalis Cardenas Garcia ,  Qingzhong Yu ,  Tonya L. Taylor

IPC分类号： C12N7/00 ,  C07K14/54 ,  A61K39/17 ,  A61K39/12 ,  A61P31/14 ,  A61K39/00

摘要： An altered avian NDV that contains the coding sequence of avian interleukin-4 (IL-4), or a portion thereof, in the reverse orientation suppresses in-ovo IL-4 production via RNAi when administered to embryonic birds. An immunogenic composition containing this altered NDV is included in this invention. The altered avian NDV can, optionally contain a polynucleotide encoding a heterologous antigen from a heterologous avian pathogen and can produce said heterologous antigen in-ovo.

公开(公告)号：US10118898B2

公开(公告)日：2018-11-06

申请号：US15249719

申请日：2016-08-29

申请人： University of Georgia Research Foundation, Inc.

发明人： Richard W. Morrison ,  Douglas Michael Jackson ,  Daniel Richard Morrison

IPC分类号： C07D209/14 ,  C07D209/16 ,  C07D233/64 ,  C07C249/02 ,  C07C209/52 ,  C07D207/06 ,  C07B37/06 ,  C07C209/68 ,  C07C213/08 ,  C07C213/02

摘要： The present application provides methods for decarboxylation of amino acids via imine formation with a catalyst under pressurized, heated, conditions in either a microwave or oil bath, with optional recovery of the catalyst and/or catalyst byproduct.

公开(公告)号：US10022451B2

公开(公告)日：2018-07-17

申请号：US14709090

申请日：2015-05-11

申请人： University of Georgia Research Foundation, Inc.

发明人： Jin Xie ,  Zipeng Zhen ,  Wei Tang

IPC分类号： A61N5/06 ,  A61K47/48 ,  A61K31/704 ,  A61K9/127 ,  A61K41/00 ,  A61K33/06 ,  A61K33/22 ,  A61K33/26 ,  A61K33/30

摘要： The subject matter disclosed herein relates to compositions that contain a protein cage and a therapeutic agent, such as a photosensitizer. The protein cage is a protein that binds metal ion. The composition can further contain a cell recognition moiety. The methods disclosed are for permeabilizing the endothelial lining of a cancerous tissue or for treating a cancerous tissue to cause therapeutic injury resulting in the reduction of at least one of the surface area, the depth, and the amount of the tissue affected by the cancerous condition, in a subject.

公开(公告)号：USPP28624P3

公开(公告)日：2017-11-14

申请号：US14756566

申请日：2015-09-17

申请人： University of Georgia Research Foundation, Inc.

发明人： D. Scott NeSmith

IPC分类号： A01H5/08

摘要： The new variety ‘T-460’ ripens around mid June in southern Georgia and early July in middle Georgia. The fruit of the new variety ‘T-460’ are large, with good scar and very good color. The new variety ‘T-460’ is moderately vigorous with an estimated chilling requirement of about 500 to 550 hours at or below approximately 7° C. The asexually reproduced variety is reliably propagated vegetatively.

公开(公告)号：US09725405B2

公开(公告)日：2017-08-08

申请号：US14967896

申请日：2015-12-14

申请人： UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC.

发明人： Geert-Jan Boons ,  Jun Guo ,  Xinghai Ning ,  Margaretha Wolfert

IPC分类号： C07C271/34 ,  C07C35/37 ,  C07C49/683 ,  C07C211/42 ,  C07C251/44 ,  C07C251/58 ,  C07D249/16 ,  C07D261/20 ,  C07D271/12 ,  C07D307/94 ,  C07D311/90 ,  C07D495/04 ,  A61K47/48 ,  A61K49/00 ,  C07H21/00 ,  C07K2/00 ,  C07K14/00 ,  G01N33/58

CPC分类号： C07C251/58 ,  A61K47/54 ,  A61K47/542 ,  A61K47/61 ,  A61K47/62 ,  A61K47/64 ,  A61K47/6803 ,  A61K47/6921 ,  A61K49/0021 ,  A61K49/0043 ,  A61K49/0052 ,  C07C35/37 ,  C07C49/683 ,  C07C211/42 ,  C07C251/44 ,  C07C271/34 ,  C07C2603/36 ,  C07D249/16 ,  C07D261/20 ,  C07D271/12 ,  C07D307/94 ,  C07D311/90 ,  C07D495/04 ,  C07H21/00 ,  C07K2/00 ,  C07K14/00 ,  G01N33/582

摘要： 1,3-Dipole-functional compounds (e.g., azide functional compounds) can be reacted with certain alkynes in a cyclization reaction to form heterocyclic compounds. Useful alkynes (e.g., strained, cyclic alkynes) and methods of making such alkynes are also disclosed. The reaction of 1,3-dipole-functional compounds with alkynes can be used for a wide variety of applications including the immobilization of biomolecules on a substrate.