Gene SCC-112 and diagnostic and therapeutic uses thereof
    71.
    发明授权
    Gene SCC-112 and diagnostic and therapeutic uses thereof 失效
    基因SCC-112及其诊断和治疗用途

    公开(公告)号:US07351811B2

    公开(公告)日:2008-04-01

    申请号:US10679580

    申请日:2003-10-06

    CPC classification number: C07K14/82 A61K38/00 G01N33/574

    Abstract: A gene that is a modulator of tumor growth and metastasis in certain cancer types is provided. SCC-112 (about 150 kDa) and/or a mutant form of SCC-112 (about 65 kDa) is a tumor suppressor molecule. This gene and corresponding polypeptide have diagnostic and therapeutic application for detecting and treating cancers that involve expression of SCC-112 such as breast and kidney cancers.

    Abstract translation: 提供了一种在某些癌症类型中是肿瘤生长和转移的调节剂的基因。 SCC-112(约150kDa)和/或突变形式的SCC-112(约65kDa)是肿瘤抑制分子。 该基因和相应的多肽具有用于检测和治疗涉及表达SCC-112(例如乳腺和肾癌)的癌症的诊断和治疗应用。

    Methods of controlling fines migration in a well

    公开(公告)号:US10822538B2

    公开(公告)日:2020-11-03

    申请号:US16044624

    申请日:2018-07-25

    Abstract: A method of treating a subterranean formation penetrated by a wellbore comprises introducing into the subterranean formation a treatment fluid comprising encapsulated particles having a core of a crosslinking agent and a shell of a chitosan encapsulant disposed on the core; releasing the crosslinking agent from the encapsulated particles with an acid; reacting the released crosslinking agent with the chitosan encapsulant or a derivative thereof forming a polymerized chitosan; and consolidating a plurality of particles in the subterranean formation with the polymerized chitosan.

    TRACHEOSTOMY TUBE MONITOR AND ALERTING APPARATUS

    公开(公告)号:US20200001028A1

    公开(公告)日:2020-01-02

    申请号:US16457175

    申请日:2019-06-28

    Abstract: A tracheostomy tube monitor and alerting apparatus includes: (i) a passive humidification device; and (ii) an integrated monitoring assembly fitted in an opening of a rear sidewall of the passive humidification device. The passive humidification device is configured to be connected to a connector of a tracheostomy tube of a patient. Once connected, the monitoring assembly of the apparatus can begin measuring one or more physiological parameters, such as, air flow, oxygen level, carbon dioxide level, pressure, and moisture. The measurements are compared against threshold values that denote blockage or decannulation. When these threshold values are surpassed, an alarm is actuated to alert a caregiver that the patient may be experiencing obstruction or decannulation of the tracheostomy tube.

    HYBRID SYNCHRONOUS/ASYNCHRONOUS COUNTER
    79.
    发明申请
    HYBRID SYNCHRONOUS/ASYNCHRONOUS COUNTER 有权
    混合同步/异步计数器

    公开(公告)号:US20150188546A1

    公开(公告)日:2015-07-02

    申请号:US14141458

    申请日:2013-12-27

    CPC classification number: H03K23/588 H03K19/0008 H03K21/10 H03K21/12 H03K23/58

    Abstract: A hybrid counter generates a multi-bit hybrid counter value. The hybrid counter includes two or more asynchronous counters, each configured to generate a subset of the bits of the multi-bit hybrid counter value. The asynchronous counters are interconnected by a logic gate and a clock gating circuit. The logic gate generates an asynchronous logic value based on the bits generated by the previous asynchronous counters. The clock gating circuit re-times the asynchronous logic value to generate a synchronous logic value that is used to toggle the next asynchronous counter. The hybrid counter functions more accurately than conventional asynchronous counters and with less power than conventional synchronous counters.

    Abstract translation: 混合计数器产生多位混合计数器值。 混合计数器包括两个或多个异步计数器,每个异步计数器被配置为生成多比特混合计数器值的比特的子集。 异步计数器由逻辑门和时钟门控电路互连。 逻辑门根据以前的异步计数器产生的位产生异步逻辑值。 时钟门控电路重新计时异步逻辑值以产生用于切换下一个异步计数器的同步逻辑值。 混合计数器的功能比传统的异步计数器更精确,功耗比传统的同步计数器少。

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