公开(公告)号：US20180028502A1

公开(公告)日：2018-02-01

申请号：US15495841

申请日：2017-04-24

申请人： Kyungpook National University Industry-Academic Cooperation Foundation ,  KYUNGPOOK NATIONAL UNIVERSITY HOSPITAL

发明人： Kyoungho SUK ,  Gyun Jee SONG ,  Youngpyo NAM ,  Myungjin JO

IPC分类号： A61K31/42

CPC分类号： A61K31/42

摘要： There is provided a composition for treating a neuroinflammatory disease comprising a N-carbamoylated urethane compound which has an effect of inhibiting the activity of microglia or astrocytes and the production of nitric oxide (NO) and TNF-α, and suppressing the expression of IL-1β And iNOS genes. There is also provide a method for treating a neuroinflammatory disease, the method comprising the step of administering a N-carbamoylated urethane compound. Due to its above mentioned effects, the N-carbamoylated urethane compound according to the present invention can be useful for the treatment of neuroinflammatory diseases.

公开(公告)号：US09874533B2

公开(公告)日：2018-01-23

申请号：US14555848

申请日：2014-11-28

申请人： Kyungpook National University Industry-Academic Cooperation Foundation

发明人： Hyun Woo Lee ,  Jong Won Lee

IPC分类号： G01N25/18

CPC分类号： G01N25/18

摘要： An apparatus for measuring an overall heat transfer coefficient may include an internal case provided using a heat insulation material and having an open upper portion, an external case configured to enclose outer sides excluding an upper portion of the internal case, and provided using a heat insulation material, a temperature adjusting portion configured to adjust an internal temperature of the external case and an internal temperature of the internal case, and a blocking portion disposed in an upper portion of the internal case to seal the internal case, in which the blocking portion may be configured to implement various covering conditions through a combination of a covering material and a thermal screen.

公开(公告)号：US09846266B2

公开(公告)日：2017-12-19

申请号：US14914911

申请日：2014-11-04

申请人： KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION

发明人： Hak-Rin Kim

IPC分类号： G02F1/1333 ,  G02B5/30 ,  B29D11/00 ,  G02F1/1337

CPC分类号： G02B5/3016 ,  B29D11/00644 ,  B29D11/00788 ,  G02F1/133711 ,  G02F1/133788 ,  G02F2001/133715 ,  G02F2001/133776

摘要： Provided is a liquid crystalline polymer film where noise caused by diffraction light is removed. The liquid crystalline polymer film is configured to include a first liquid crystalline polymer film formed by simultaneously performing a bottom-up alignment method by a lower alignment film and a top-down alignment method by using a groove structure and a second liquid crystalline polymer film formed on an upper portion of the first liquid crystalline polymer film by overcoating. The second liquid crystalline polymer film is configured so as to satisfy a refractive index matching condition with respect to the first liquid crystalline polymer film, so that noise caused by undesired diffraction phenomenon generated by the groove structure on the upper surface of the first liquid crystalline polymer film is removed.

公开(公告)号：US09829634B2

公开(公告)日：2017-11-28

申请号：US14761859

申请日：2014-01-16

申请人： KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION ,  GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY

发明人： Ho Lee ,  Ik Bu Sohn ,  Chang Hwan Kim ,  Myung Jin Jeon ,  Ho Yong Park

IPC分类号： G02B6/26 ,  G02B6/04 ,  F21V8/00 ,  G02B6/36 ,  G02B6/35

CPC分类号： G02B6/262 ,  G02B6/0008 ,  G02B6/04 ,  G02B6/353 ,  G02B6/3624

摘要： A bundled optical fiber probe according to an embodiment of the present invention includes: a forward irradiation unit including a forward irradiation optical fiber disposed at the center thereof, the forward irradiation optical fiber having a flat end surface; and a side irradiation unit including a side irradiation optical fiber disposed at the periphery of the forward irradiation unit, the side irradiation optical fiber having an inclined end surface to laterally reflect a laser beam, wherein the forward irradiation unit and the side irradiation unit can be formed as a single bundle.

公开(公告)号：US20170267723A1

公开(公告)日：2017-09-21

申请号：US15612500

申请日：2017-06-02

申请人： KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY - ACADEMIC COOPERATION FOUNDATION

发明人： JAE SUNG BAE ,  HEE KYUNG JIN ,  MIN HEE PARK

IPC分类号： C07K7/08 ,  A61K38/00

CPC分类号： C07K7/08 ,  A61K38/00

摘要： The present disclosure relates to a novel peptide for preventing or treating bone diseases. Further, the present disclosure relates to a polynucleotide encoding the peptide, a vector including the polynucleotide, a host cell transformed by the vector, and a method for producing the peptide by using the host cell. Furthermore, the present disclosure relates to a composition for preventing or treating bone diseases, including the novel peptide. The novel peptide according to the present disclosure induces mobilization of hematopoietic stem cells to blood and causes a decrease in the number of osteoclasts, and, thus, decreases bone erosion caused by osteoclasts, thereby suppressing progress of an osteoporotic lesion. Further, the novel peptide is safe since it does not cause rejection in the body. Furthermore, since the novel peptide is formed of 16 short amino acids, a low dose of the peptide can relieve symptoms of osteoporosis.

公开(公告)号：US09744992B2

公开(公告)日：2017-08-29

申请号：US14788143

申请日：2015-06-30

申请人： Kyungpook National University Industry-Academic Cooperation Foundation

发明人： Dong Seog Han ,  In Seok Yang

IPC分类号： B62D7/15 ,  B62D5/00 ,  B62D6/02 ,  B62D6/00

CPC分类号： B62D7/159 ,  B62D5/001 ,  B62D5/003 ,  B62D6/002

摘要： The following description relates to a fault tolerant apparatus for an independent controlled steering in a four wheel system, particularly a fault tolerant apparatus for an independent controlled steering in a four wheel system which can stabilizes a vehicle body through actively adjusting a steering angle of a vehicle and a velocity of a vehicle according to a breakdown environment and a vehicle driving road environment. Further, a fault tolerant apparatus for an independent controlled steering in a four wheel system that may assist a safe driving environment by adjusting a turning function adoptively to a surrounding road environment.

公开(公告)号：US20170224781A1

公开(公告)日：2017-08-10

申请号：US15424185

申请日：2017-02-03

申请人： KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION

发明人： Jae Sung Bae ,  Hee Kyung Jin ,  Min Hee Park

IPC分类号： A61K38/22

CPC分类号： A61K38/2271

摘要： There is provided a method for treating or reducing an anticancer agent-induced nephrotoxic injury, the method comprising the step of administering a Y1 receptor activator in an amount effective to treat or reduce the anticancer agent-induced nephrotoxic injury in a subject. Further, there is provided a method for screening an agent for treating or reducing an anticancer agent-induced nephrotoxic injury, the method comprising (a) applying a candidate material to a test sample of renal tissues or cells; and (b) identifying a Y1 receptor signaling in the test sample of renal tissues or cells.

公开(公告)号：US09724334B1

公开(公告)日：2017-08-08

申请号：US15417315

申请日：2017-01-27

申请人： Kyungpook National University Industry-Academic Cooperation Foundation

发明人： Jae-Sung Bae ,  Hee Kyung Jin ,  Min Hee Park

IPC分类号： A61K31/4192 ,  C07D249/04

CPC分类号： A61K31/4192 ,  C07D249/04

摘要： A method for treating a neurodegenerative disease and depression, the method comprising administering to a subject in need thereof an effective amount of a composition comprising derivatives of 2-amino-2-(1-dodecyl-1H-1,2,3-triazol-4-yl)propane-1,3-diol as an active ingredient.

公开(公告)号：US20170183381A1

公开(公告)日：2017-06-29

申请号：US15454216

申请日：2017-03-09

申请人： KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY - ACADEMIC COOPERATION FOUNDATION

发明人： Jae Sung Bae ,  Hee Kyung Jin ,  Min Hee Park

IPC分类号： C07K7/08

CPC分类号： C07K7/08 ,  A61K38/00 ,  A61K38/10 ,  A61K38/2271

摘要： The present disclosure relates to a novel peptide for preventing or treating bone diseases. Further, the present disclosure relates to a polynucleotide encoding the peptide, a vector including the polynucleotide, a host cell transformed by the vector, and a method for producing the peptide by using the host cell. Furthermore, the present disclosure relates to a composition for preventing or treating bone diseases, including the novel peptide. The novel peptide according to the present disclosure induces mobilization of hematopoietic stem cells to blood and causes a decrease in the number of osteoclasts, and, thus, decreases bone erosion caused by osteoclasts, thereby suppressing progress of an osteoporotic lesion. Further, the novel peptide is safe since it does not cause rejection in the body. Furthermore, since the novel peptide is formed of 15 short amino acids, a low dose of the peptide can relieve symptoms of osteoporosis.

公开(公告)号：US09667111B2

公开(公告)日：2017-05-30

申请号：US14310547

申请日：2014-06-20

申请人： SAMSUNG ELECTRONICS CO., LTD. ,  Kyungpook National University Industry-Academic Cooperation Foundation

发明人： Won-ho Kim ,  Seong-taek Lim ,  Hong-soon Choi ,  Jin-woo Cho

IPC分类号： H02K1/27

CPC分类号： H02K1/2766 ,  H02K1/276 ,  H02K1/2773 ,  H02K1/278

摘要： Exemplary embodiments disclose a rotor of an electric motor and an electric motor using the same. The rotor includes a core which includes a plurality of protrusion portions which are arranged along an outer circumference of the core and protrude radially to an outer portion of the core, and a plurality of concave portions interposed between the protrusion portions; a plurality of permanent magnets which are respectively disposed at the plurality of concave portions; and a plurality of pole pieces which are disposed at the plurality of concave portions and at outer sides of the plurality of permanent magnets. A length of each of the plurality of pole pieces in an axial direction is shorter than a length of each of the plurality of protrusion portions in the axial direction.