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公开(公告)号:US20250026887A1
公开(公告)日:2025-01-23
申请号:US18238314
申请日:2023-08-25
Inventor: Ki-Ho NAM , Seongjun KHIM , Yun Chan HWANG
Abstract: A manufacturing method of a porous polyimide film, includes: preparing a polyamic acid solution at a concentration of 10 to 30 wt % by dissolving a diamine compound and a dianhydride in a solvent; applying the prepared polyamic acid solution to a substrate to prepare a film and then immersing the same in a non-solvent for 30 minutes to 180 minutes; and taking out the immersed film and thermally curing the same; and a porous polyimide film manufactured thereby.
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公开(公告)号:US20250000876A1
公开(公告)日:2025-01-02
申请号:US18748247
申请日:2024-06-20
Applicant: Gachon University of Industry-Academic cooperation Foundation , Eulji University Industry Academy Cooperation Foundation , Kyungpook National University Industry-Academic Cooperation Foundation
Inventor: Dongwoo KHANG , Jun-Young PARK , Youn Joo KANG , Sang-Hyun KIM , Song KWON
IPC: A61K31/573 , A61K47/69 , A61P29/00 , B82Y5/00
Abstract: The present invention provides a novel therapeutic agent for treating inflammatory diseases which reduces the pro-inflammatory response and increases M2 macrophages according to the repolarization of macrophages, thereby exhibiting fewer side effects and excellent anti-inflammatory effects even at low doses compared to conventional steroid anti-inflammatory agent.
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公开(公告)号:US20240336632A1
公开(公告)日:2024-10-10
申请号:US18295000
申请日:2022-08-04
Inventor: Jeongsoo Yoo , Kyungwon Kim
CPC classification number: C07F1/08 , A61K51/0482 , A61K51/1234 , A61K2121/00 , A61K2123/00 , C07B2200/05
Abstract: The present invention relates to a novel compound comprising an ester group and uses thereof and, more particularly, to a novel compound that exhibits excellent visualization ability in a tumor by using the difference in activity of esterase for each organ in the body, and to uses therefor for diagnosing or treating cancer. A novel compound of chemical Formulas 1 to 8 according to the present invention exhibits selectivity according to the difference in activity of esterase for each organ due to ester residue in a structure, and thus is extremely effective in visualizing pancreatic cancer, etc.
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公开(公告)号:US20240332765A1
公开(公告)日:2024-10-03
申请号:US18625650
申请日:2024-04-03
Inventor: Kang Wook Kim , Byung Cheol Min , Jeong Sik Choi
Abstract: The present disclosure relates to ultra-high speed digital signal integrity improving structures. Each structure in the present disclosure includes a first unit structure and a second unit structure of the same or different shapes arranged to face each other on the left and right sides along a longitudinal direction of a balanced line, centered around a coplanar stripline (CPS) or parallel stripline (PSL) formed on a substrate. At least one of the first unit structure and the second unit structure includes a first side close to the balanced line and having a linear or curve shape; a second side facing the first side; and left and right sides connecting the first side and the second side. Here, the width of the first side is less than or equal to that of the second side, the left and right sides have a linear or non-linear slope, and the width from the first side to the second side is configured to change continuously or discontinuously. When the structures of the present disclosure are disposed around a balanced line, it has the advantage of being able to recover the distorted phase autonomously while rejecting a common-mode signal in a frequency band up to 40 GHz or more.
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公开(公告)号:US12102666B2
公开(公告)日:2024-10-01
申请号:US17281952
申请日:2020-07-02
Inventor: Jung Min Kim , Jong Sook Jin , Shukho Kim
IPC: A61K38/47 , A01N63/50 , A23C9/152 , A23K20/147 , A23K20/195 , A23L3/3463 , A23L3/3526 , A23L33/10 , A23L33/175 , A61P31/04 , A01P1/00
CPC classification number: A61K38/47 , A01N63/50 , A23C9/1526 , A23K20/147 , A23K20/195 , A23L3/34635 , A23L3/3526 , A23L33/127 , A23L33/175 , A61P31/04 , A01P1/00 , A23V2002/00
Abstract: The present invention relates to a method of using a recombinant antibacterial protein, termed Ablysin, for effectively killing multidrug-resistant pathogenic bacteria. The recombinant protein Ablysin is administered to prevent or treat infectious diseases caused by the antibiotic-resistant bacteria Acinetobacter baumannii. Ablysin can be widely used in antibiotics, disinfectants, food additives, feed additives, and the like. In particular, the Ablysin protein uses peptidoglycan, a component of the cell wall of bacteria, as a substrate and exhibits bacterial killing ability due to peptidoglycan degradation. The Ablysin of the present invention can be applied in the pharmaceutical industry, food industry, biotechnology, or similar industries, as the protein effectively kills bacteria at a desired place or in a target substance without problems of resistance that occurs in other antimicrobial agents.
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公开(公告)号:US20240261734A1
公开(公告)日:2024-08-08
申请号:US18565354
申请日:2022-05-31
Inventor: Kwang Ho CHOO , Syed Salman Ali SHAH
CPC classification number: B01D65/08 , B01D67/00931 , B01D67/00933 , B01D69/02 , C02F1/44 , C02F3/1268 , C02F3/34 , B01D2321/28 , B01D2323/02 , B01D2323/12 , B01D2323/30 , B01D2325/20 , B01D2325/36
Abstract: The present disclosure relates to a membrane filter for water and wastewater treatment including a membrane filter, hydrophilic polymers formed on the membrane filter; and quorum quenching microorganisms cross-linked with the membrane filter by the hydrophilic polymer. The quorum quenching microorganisms are attached to the surface of the membrane filter for water and wastewater treatment, resulting in a higher initial permeation pressure than a conventional membrane, but the quorum quenching microorganisms may effectively prevent the phenomenon of quorum sensing, allowing the formation of a biofilm, thereby improving the life of the membrane filter for water and wastewater treatment.
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公开(公告)号:US20240197672A1
公开(公告)日:2024-06-20
申请号:US18515486
申请日:2023-11-21
Inventor: Sang-Han LEE , Borim SONG
IPC: A61K31/353 , A61K8/49 , A61P17/00 , A61Q19/02
CPC classification number: A61K31/353 , A61K8/498 , A61P17/00 , A61Q19/02
Abstract: The present invention relates to a composition for inhibiting skin pigmentation through enhanced autophagy activity, comprising procyanidin A2 and quercetin as active ingredients. The combination of procyanidin A2 and quercetin compounds not only inhibits tyrosinase but also increases autophagy activity, thus showing remarkable effectiveness in inhibiting melanin synthesis. Therefore, this composition can be advantageously used in various materials, including food products, cosmetic compositions, and pharmaceutical compositions, associated with skin pigmentation.
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公开(公告)号:US20240142347A1
公开(公告)日:2024-05-02
申请号:US18280272
申请日:2021-12-29
Inventor: Dongjun SUH , Geonkyo HONG , Jeonghoon CHOI
CPC classification number: G01M99/005 , G05B23/0229
Abstract: A system for diagnosing a machine failure according to an embodiment of the inventive concept includes a pre-processing module that receives a primitive signal in a time-amplitude domain to generate a Mel spectrum image in a time-frequency domain, a feature extraction module that learns features of the Mel spectrum image to output an Euclidean distance between a latent variable and a centroid, a failure diagnosis module that performs classification into a preset number of classes on the basis of the Euclidean distance between the latent variable and the centroid, and a result output module that outputs whether a failure has occurred according to a class classified by the failure diagnosis module.
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公开(公告)号:US11968990B2
公开(公告)日:2024-04-30
申请号:US17653992
申请日:2022-03-08
Applicant: CJ CHEILJEDANG CORPORATION , KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
Inventor: Young Mi Lee , Seong Bo Kim , Yang Hee Kim , Seong Jun Cho , Myung Sook Choi , Young Ji Han , Ji Young Choi , Su Jung Cho , Un Ju Jung , Eun Young Kwon
IPC: A23C11/02
CPC classification number: A23C11/02 , A23C2260/20 , A23V2002/00 , A23V2250/1618 , A23V2250/18 , A23V2250/54246 , A23V2250/616
Abstract: The present application relates to creamer comprising vegetable lipids, casein, maltose, phosphates, and allulose.
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公开(公告)号:US20240133080A1
公开(公告)日:2024-04-25
申请号:US18383088
申请日:2023-10-23
Applicant: POSTECH Research and Business Development Foundation , KYUNGPOOK NATIONAL UNIVERSITY HOSPITAL , Kyungpook National University Industry-Academic Cooperation Foundation
Inventor: Joon Won KIM , Jongkyeong Lim , Jaechan Park
CPC classification number: D01D5/28 , A61L24/043 , A61M25/0026 , D01D4/02 , D01D5/06 , A61L2300/418 , A61M2025/0004 , A61M2025/0039 , A61M2025/0042 , D10B2509/00
Abstract: Disclosed is an apparatus for continuous spinning of coagulative polymeric microfibers comprising an outer microcatheter, an inner microcatheter having a smaller diameter than the outer microcatheter and inserted inside the outer microcatheter, a double lumen part in which the outer microcatheter and the inner microcatheter are coaxially superimposed with a radially spaced interstitial space, and a single lumen part formed by the outer microcatheter from an end of the inner microcatheter to an end of the outer microcatheter. A core fluid supplied through an interior of the inner microcatheter comprises a coagulative polymeric fluid, and a sheath fluid supplied through the interstitial space comprises a fluid including saline, wherein the core fluid and the sheath fluid may be configured to flow coaxially in the single lumen part to generate and discharge a coagulative polymeric microfiber.
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