公开(公告)号：US07939093B2

公开(公告)日：2011-05-10

申请号：US11890400

申请日：2007-08-06

Applicant: Matthias John ,  Stefan Lautenschläger ,  Norbert Rahn

Inventor： Matthias John ,  Stefan Lautenschläger ,  Norbert Rahn

IPC: A61B5/05

CPC classification number: A61B6/504 ,  A61B5/0275 ,  A61B6/032 ,  A61B6/481 ,  A61B6/503 ,  A61B6/507

Abstract: The invention relates to a method for differentially representing myocardial tissue in different states of damage, comprising the following steps: administering a myocardium-suitable contrast agent to a patient under examination; entering at least one patient-specific parameter affecting the speed of uptake by and elimination from the myocardium of said contrast agent; calculating a point in time after administration of the contrast agent at which a difference between a contrast agent content in necrotic myocardial tissue and a contrast agent content in non-necrotic myocardial tissue attains a maximum value, on the basis of the at least one patient-specific parameter, and carrying out, at the point in time calculated, a late-phase CT scan for accentuation of necrotic myocardial tissue compared to non-necrotic myocardial tissue. The invention likewise relates to apparatus, in particular for carrying out the method.

Abstract translation: 本发明涉及用于差异代表不同损伤状态的心肌组织的方法，包括以下步骤：向被检查的患者施用适合心肌的造影剂; 输入至少一个影响所述造影剂的心肌的摄取速度和消除速度的患者特异性参数; 计算施用造影剂之后的时间点，其中所述造影剂中的坏死心肌组织中的造影剂含量与非坏死性心肌组织中的造影剂含量之间的差异达到最大值，基于至少一个患者 - 具体参数，并且在计算的时间点进行与非坏死心肌组织相比的坏死心肌组织的晚期CT扫描。 本发明同样涉及装置，特别是用于实施该方法。

公开(公告)号：US07787941B2

公开(公告)日：2010-08-31

申请号：US11378060

申请日：2006-03-17

Applicant: Jan Boese ,  Martin Kleen ,  Norbert Rahn

Inventor： Jan Boese ,  Martin Kleen ,  Norbert Rahn

IPC: A61B5/04

CPC classification number: A61B5/6843 ,  A61B5/0424 ,  A61B5/6885 ,  A61B5/7415 ,  A61B2017/00128 ,  A61B2017/00199

Abstract: Medical examination and/or treatment system, configured to capture and output at least one parameter to be monitored during examination and/or treatment, with the system being configured to evaluate the at least one captured parameter and to output an acoustic signal that can be modified as a function of the result of the evaluation.

Abstract translation: 医疗检查和/或治疗系统被配置成在检查和/或治疗期间捕获并输出待监测的至少一个参数，其中该系统被配置为评估该至少一个捕获的参数并输出可被修改的声信号 作为评估结果的函数。

公开(公告)号：US07760926B2

公开(公告)日：2010-07-20

申请号：US11453623

申请日：2006-06-15

Applicant: Jan Boese ,  Andreas Meyer ,  Marcus Pfister ,  Norbert Rahn

Inventor： Jan Boese ,  Andreas Meyer ,  Marcus Pfister ,  Norbert Rahn

IPC: G06K9/00

CPC classification number: G03B42/026 ,  A61B6/02 ,  A61B6/4441 ,  A61B6/466 ,  A61B6/469 ,  A61B6/481 ,  A61B6/503 ,  A61B6/504 ,  A61B6/541 ,  A61B34/20 ,  A61B90/37 ,  A61B2017/00703 ,  A61B2090/364 ,  A61B2090/376 ,  G03B42/021

Abstract: The invention relates to a method and a device for marking three-dimensional structures on two-dimensional projection images of an object, with which a position marker is determined on two projection images of the object recorded from different projection directions, from which the position of the position marker in the three-dimensional space is calculated so that further, subsequently recorded projection images can be displayed superimposed by the position marker.

Abstract translation: 本发明涉及一种用于标记物体的二维投影图像上的三维结构的方法和装置，利用该方法和装置在从不同投影方向记录的物体的两个投影图像上确定位置标记， 计算三维空间中的位置标记，使得随后记录的投影图像可以通过位置标记叠加显示。

公开(公告)号：US07664542B2

公开(公告)日：2010-02-16

申请号：US11496069

申请日：2006-07-28

Applicant: Jan Boese ,  Martin Kleen ,  Klaus Klingenbeck-Regn ,  Marcus Pfister ,  Norbert Rahn

Inventor： Jan Boese ,  Martin Kleen ,  Klaus Klingenbeck-Regn ,  Marcus Pfister ,  Norbert Rahn

IPC: A61B5/05 ,  A61B6/00

CPC classification number: G06T7/55 ,  G06T7/38 ,  G06T7/50 ,  G06T2207/30004

Abstract: The invention relates to a method for registering intra-operative image data set with pre-operative 3D image data set, including: spatially calibrating an optical 3D sensor system with an intra-operative imaging modality, intra-operatively detecting the surface of an examination area of interest with the 3D sensor system to produce an intra-operative surface mask, intra-operatively recording the area of interest for examination with the intra-operative modality at least partly containing the intra-operative surface mask to obtain an intra-operative image data set, computing the same surface from the pre-operative 3D image data set containing the detected surface to obtain a pre-operative surface mask, registering the intra-operative and pre-operative surface mask with each other, determining a mapping specification between pre-operative 3D image data set and intra-operative image data set based on the calibration and the registration, and overlaying the intra-operative image data set with the pre-operative 3D data set based on the mapping specification.

Abstract translation: 本发明涉及一种用于记录术前图像数据组与手术前3D图像数据集的方法，所述方法包括：空间校准具有术中成像模态的光学3D传感器系统，操作内检测检查区域的表面 感兴趣的3D传感器系统以产生术中表面掩模，用至少部分地包含术中表面掩模的手术内模式操作内记录用于检查的感兴趣区域以获得手术中图像数据 设置，从包含检测到的表面的术前3D图像数据集计算相同的表面，以获得术前表面掩模，将手术前和手术前表面掩模彼此对准， 基于校准和注册的手术3D图像数据集和手术中图像数据集合，并且将术中图像数据集w 基于映射规范的术前3D数据集。

公开(公告)号：US20090306500A1

公开(公告)日：2009-12-10

申请号：US12239300

申请日：2008-09-26

Applicant: Norbert Rahn ,  Erik Busch ,  Alois Noettling

Inventor： Norbert Rahn ,  Erik Busch ,  Alois Noettling

IPC: A61B6/00 ,  A61F2/24 ,  A61B5/0402 ,  G06K9/00

CPC classification number: G16H50/50 ,  A61B6/4464 ,  A61B34/10 ,  A61B90/37 ,  A61B2017/00243 ,  A61B2090/376 ,  G06F19/3481

Abstract: A system and method of treating a patient is described, where an implantable device is introduced into the patient and guided to an appropriate location using a 2-dimentsional X ray taken prior to the introduction of the device, and a fluoroscopic image taken from the same aspect during the procedure, and using the same portion of a physiological cycle. The implantable device may be a percutaneous aortic heart valve (PHV), and the location of the device may be determined with respect to specific bodily structures identified in the 2-dimensional X-ray, such as the aortic valve and the coronary ostia. The installation position of the device is selected so as to avoid obstruction of the coronary ostia.

Abstract translation: 描述了一种治疗患者的系统和方法，其中将可植入装置引入患者并使用在引入装置之前拍摄的2维X射线将其引导到适当的位置，并从其中取出荧光镜图像 并且使用生理周期的相同部分。 可植入装置可以是经皮主动脉瓣膜（PHV），并且该装置的位置可以根据在二维X射线（例如主动脉瓣和冠状动脉口）中识别的特定身体结构来确定。 选择装置的安装位置以避免阻塞冠状动脉口。

公开(公告)号：US07613499B2

公开(公告)日：2009-11-03

申请号：US11392035

申请日：2006-03-29

Applicant: Norbert Rahn ,  Arne Westphal

Inventor： Norbert Rahn ,  Arne Westphal

IPC: A61B5/04

CPC classification number: A61B5/042 ,  A61B5/06 ,  A61B5/065 ,  A61B5/7445 ,  A61B6/12 ,  A61B18/1492 ,  A61B2018/00351

Abstract: A method for providing measuring data for the precise local positioning of an ablation catheter comprises the recording of electrophysiological potential curves in a plurality of positions of the ablation catheter with regard to a potential measurement on a reference catheter. An x-ray image is recorded in each of the positions and the position of the ablation catheter in each instance on the x-ray image is characterized by a marker. The electrophysiological potential curves are coupled in a data-related manner with the markers. When a marker on the screen displaying the x-ray image is clicked on, the associated electrophysiological potential curves appear highlighted on another screen, if necessary in color or with increased brightness. Conversely, the x-ray image with the marker is queried, i.e. displayed and the marker highlighted when the potential curve is activated on a screen displaying the potential curve.

Abstract translation: 提供用于消融导管的精确的局部定位的测量数据的方法包括关于在参考导管上的潜在测量在消融导管的多个位置记录电生理电位曲线。 x射线图像被记录在每个位置中，并且X射线图像中的每一个消融导管的位置的特征在于标记。 电生理电位曲线以数据相关的方式与标记相结合。 当点击显示x射线图像的屏幕上的标记时，相关联的电生理学电位曲线在另一个屏幕上显示高亮显示，如果需要，颜色或亮度增加。 相反，查询具有标记的X射线图像，即显示，并且当在显示电位曲线的屏幕上激活电位曲线时，该标记被突出显示。

公开(公告)号：US07568837B2

公开(公告)日：2009-08-04

申请号：US12077685

申请日：2008-03-20

Applicant: Benno Heigl ,  Norbert Rahn ,  James Williams

Inventor： Benno Heigl ,  Norbert Rahn ,  James Williams

IPC: A61B6/02

CPC classification number: G03B42/026 ,  A61B6/02 ,  A61B6/08 ,  A61B6/12 ,  A61B6/4441 ,  A61B6/4458 ,  A61B6/469 ,  A61B6/488 ,  A61B6/545

Abstract: To make optimum use of an x-ray image recording system with an x-ray C-arm, which has an x-ray radiation source and an x-ray detector and can be pivoted about any axis, 2D axis lines are plotted in two x-ray images of an object to be imaged more precisely and these 2D axis lines are used to define a 3D axis line and the x-ray image recording system is set so that it can be directly pivoted precisely about this 3D axis line. A sequence of x-ray images is then recorded in positions of the x-ray C-arm, between which the same can be pivoted about this defined axis. This displays the object optimally.

Abstract translation: 为了最佳地利用具有x射线C臂的X射线图像记录系统，X射线C臂具有x射线辐射源和X射线检测器，并且可以围绕任何轴线枢转，将2D轴线绘制在两个 要被成像的对象的X射线图像更精确，并且这些2D轴线被用于定义3D轴线，并且x射线图像记录系统被设置成使得其可以围绕该3D轴线精确地直接枢转。 然后将X射线图像的序列记录在x射线C臂的位置，在该位置上，可以围绕该限定的轴线枢转X射线图像。 这最好地显示对象。

公开(公告)号：US20090088633A1

公开(公告)日：2009-04-02

申请号：US12284597

申请日：2008-09-23

Applicant: Andreas Meyer ,  Norbert Rahn ,  Dietrich Till

Inventor： Andreas Meyer ,  Norbert Rahn ,  Dietrich Till

IPC: A61B6/00

CPC classification number: A61B6/12 ,  A61B5/042 ,  A61B5/7285 ,  A61B6/022 ,  A61B6/463 ,  A61B6/466 ,  A61B6/541

Abstract: The invention relates to a method for the combined three-dimensional image display of a catheter. The catheter is inserted into the heart area of a patient with electrophysiological data, as part of a cardiological investigation or treatment. A current position of the catheter is localized with fluoroscopy-aided. The current position of the catheter and the electrophysiological data of the patient are blended into a three-dimensional volumetric image of a structure of the heart for the combined three-dimensional image display.

Abstract translation: 本发明涉及一种用于导管组合的三维图像显示的方法。 将导管插入具有电生理数据的患者的心脏区域中，作为心脏病学调查或治疗的一部分。 导管的当前位置通过荧光透视定位。 将导管的当前位置和患者的电生理数据混合成用于组合的三维图像显示的心脏结构的三维体积图像。

公开(公告)号：US20080232554A1

公开(公告)日：2008-09-25

申请号：US12077685

申请日：2008-03-20

Applicant: Benno Heigl ,  Norbert Rahn ,  James Williams

Inventor： Benno Heigl ,  Norbert Rahn ,  James Williams

IPC: H05G1/26

CPC classification number: G03B42/026 ,  A61B6/02 ,  A61B6/08 ,  A61B6/12 ,  A61B6/4441 ,  A61B6/4458 ,  A61B6/469 ,  A61B6/488 ,  A61B6/545

Abstract: To make optimum use of an x-ray image recording system with an x-ray C-arm, which has an x-ray radiation source and an x-ray detector and can be pivoted about any axis, 2D axis lines are plotted in two x-ray images of an object to be imaged more precisely and these 2D axis lines are used to define a 3D axis line and the x-ray image recording system is set so that it can be directly pivoted precisely about this 3D axis line. A sequence of x-ray images is then recorded in positions of the x-ray C-arm, between which the same can be pivoted about this defined axis. This displays the object optimally.

Abstract translation: 为了最佳地利用具有x射线C臂的X射线图像记录系统，X射线C臂具有x射线辐射源和X射线检测器，并且可以围绕任何轴线枢转，将2D轴线绘制在两个 要被成像的对象的X射线图像更精确，并且这些2D轴线被用于定义3D轴线，并且x射线图像记录系统被设置成使得其可以围绕该3D轴线精确地直接枢转。 然后将X射线图像的序列记录在x射线C臂的位置，在该位置上，可以围绕该限定的轴线枢转X射线图像。 这最好地显示对象。

公开(公告)号：US07428296B2

公开(公告)日：2008-09-23

申请号：US11437090

申请日：2006-05-19

Applicant: Philipp Bernhardt ,  Jan Boese ,  Marcus Pfister ,  Norbert Rahn

Inventor： Philipp Bernhardt ,  Jan Boese ,  Marcus Pfister ,  Norbert Rahn

IPC: H05G1/54 ,  H05G1/02

CPC classification number: A61B6/102 ,  G05B19/4061 ,  G05B2219/45169 ,  G05B2219/49143

Abstract: The invention relates to a medical imaging system as well as a collision protection method for such a system. In this system the movement of a moveable part, e.g. a C-arm, is stopped or slowed down, if the part enters an individual protective zone enclosing the patient. This zone is calculated individually for each patient from the surface of the patient detected by an optical sensor.

Abstract translation: 本发明涉及医疗成像系统以及这种系统的碰撞保护方法。 在该系统中，可移动部件的运动，例如， 如果部件进入包围患者的个人保护区，则停止或减慢C形臂。 对于由光学传感器检测到的患者表面的每个患者，该区域被分别计算。