公开(公告)号：US20210371369A1

公开(公告)日：2021-12-02

申请号：US17286651

申请日：2019-10-18

Applicant: P2 SCIENCE, INC.

Inventor： Alexander KENDALL ,  Yonghua YANG ,  Patrick FOLEY

IPC: C07C67/313 ,  C07C51/09 ,  C07C45/40

Abstract: The present disclosure provides improved methods of performing ozonolysis on alkenes comprising non-reductive quenching of ozonide intermediates using Bronsted bases to yield aldehyde, ketone and/or carboxylic acid products.

公开(公告)号：US20210230364A1

公开(公告)日：2021-07-29

申请号：US17133520

申请日：2020-12-23

Applicant: P2 SCIENCE, INC.

Inventor： Ashoke BHATTACHARJEE ,  Patrick FOLEY ,  Yonghua YANG ,  Anam IKRAM ,  Tania SALAM ,  Michael FULLER

IPC: C08G65/34 ,  C08K5/01 ,  C08K5/092 ,  C08L65/00

Abstract: The invention contemplates certain polyethers, polyether derivatives, compositions comprising the same, and methods of making and using those same polymers.

公开(公告)号：US20200039910A1

公开(公告)日：2020-02-06

申请号：US16541065

申请日：2019-08-14

Applicant: P2 Science, Inc.

Inventor： Patrick FOLEY ,  Neil BURNS ,  Alexandre CHAPEAUX ,  Icilio ADAMI ,  Antonio MILICIA

IPC: C07C45/40 ,  B01J19/24 ,  C07C51/34 ,  B01J10/02 ,  C02F1/78

Abstract: The disclosure relates to a method of performing ozonolysis or ozone-based oxidation on a liquid or emulsified reagent using a tubular falling firm reactor with one or multiple tubes wherein the combined ozone and carrier gas flow is co-current.

公开(公告)号：US20190322635A1

公开(公告)日：2019-10-24

申请号：US16458981

申请日：2019-07-01

Applicant: P2 SCIENCE, INC.

Inventor： Patrick FOLEY ,  Yonghua YANG ,  Tania SALAM

IPC: C07D307/83 ,  A61Q13/00 ,  A61K8/49 ,  A23L27/20 ,  A23L27/00 ,  C07C45/66

Abstract: The present invention relates to the synthesis of intermediate compounds which can be used in the synthesis of mint lactone and related compounds, including 3,6-dimethylhexahydrobenzofuran-2-ones, isomers, and other derivatives.

公开(公告)号：US20190002424A1

公开(公告)日：2019-01-03

申请号：US15759135

申请日：2016-09-12

Applicant: P2 SCIENCE, INC.

Inventor： Patrick FOLEY ,  Yonghua YANG ,  Tania SALAM

IPC: C07D307/83 ,  A61Q13/00 ,  C07C45/66 ,  A61K8/49 ,  A23L27/20 ,  A23L27/00

CPC classification number: C07D307/83 ,  A23L27/2052 ,  A23L27/88 ,  A23V2002/00 ,  A61K8/4973 ,  A61Q13/00 ,  C07C45/66 ,  C07C2601/16 ,  C07C49/543

Abstract: The present invention relates to the synthesis of intermediate compounds which can be used in the synthesis of mint lactone and related compounds, including 3,6-dimethylhexahydrobenzofuran-2-ones, isomers, and other derivatives.

公开(公告)号：US10072233B2

公开(公告)日：2018-09-11

申请号：US15655374

申请日：2017-07-20

Applicant: P2 SCIENCE, INC.

Inventor： Patrick Foley ,  Tania Salam ,  Yonghua Yang

IPC: A61K8/18 ,  A61Q13/00 ,  C11B9/00 ,  C09D7/20 ,  C11D3/20 ,  C11D3/50 ,  A23L33/10 ,  A23L27/30 ,  A61K8/37 ,  A61Q19/00 ,  A61L9/00

CPC classification number: C11B9/0019 ,  A23L27/33 ,  A23L33/10 ,  A23V2002/00 ,  A61K8/375 ,  A61K2800/10 ,  A61L9/00 ,  A61L9/013 ,  A61Q13/00 ,  A61Q19/00 ,  C09D7/20 ,  C11D3/2093 ,  C11D3/50

Abstract: The present application relates to the use of neopentyl glycol diacetate (CAS 13431-57-7) as a flavor and fragrance ingredient.

公开(公告)号：US10011582B2

公开(公告)日：2018-07-03

申请号：US15119539

申请日：2015-02-18

Applicant: P2 Science, Inc.

Inventor： Patrick Foley ,  Yonghua Yang

IPC: C07D309/30 ,  C07D309/32

CPC classification number: C07D309/32 ,  C07D309/30

Abstract: The invention relates to substituted delta-lactones as well as to processes for synthesizing them, e.g., using fatty acids as starting material.

公开(公告)号：US20180163158A1

公开(公告)日：2018-06-14

申请号：US15578629

申请日：2016-06-03

Applicant: P2 SCIENCE, INC.

Inventor： Patrick FOLEY ,  Yonghua YANG

IPC: C11B9/00 ,  C07C29/143 ,  C07C45/72 ,  C07C45/69 ,  C07C49/543 ,  C07C33/14 ,  C07C43/162 ,  A23L27/20

CPC classification number: C11B9/0034 ,  A23L27/203 ,  A23V2002/00 ,  A61K8/34 ,  A61Q13/00 ,  C07C29/143 ,  C07C33/14 ,  C07C43/162 ,  C07C45/69 ,  C07C45/72 ,  C07C49/543 ,  C07C69/007 ,  C07C69/24 ,  C07C2601/16

Abstract: The present application relates to the preparation of cyclohexyl-alkyl carbinols, including 1-(cyclohex-3-en-1-yl)-2-methylpropan-1-ol, which possesses a minty aroma that can be described as fresh, invigorating, and menthol-like, and also possesses cooling properties. The use of cyclohexyl-alkyl carbinols as readily accessible and cost effective fragrance, flavor, and cooling ingredients, and potential applications thereof is also described.

公开(公告)号：US20170283553A1

公开(公告)日：2017-10-05

申请号：US15507640

申请日：2015-08-28

Applicant: P2 Science, Inc.

Inventor： Patrick FOLEY ,  Yonghua YANG

IPC: C08G65/34 ,  C07C41/01 ,  C08G65/00 ,  C07C43/178

CPC classification number: C08G65/34 ,  C07C41/01 ,  C07C43/1785 ,  C08G65/002 ,  C08G65/2642 ,  C08G65/2678 ,  C08G65/2696 ,  C08G65/3255 ,  C08G2650/64

Abstract: The invention relates to polyethers, polyamines, and polythioethers, as well as to processes for synthesizing them, e.g., using olefins as starting material.

公开(公告)号：US20170113988A1

公开(公告)日：2017-04-27

申请号：US15317642

申请日：2015-06-10

Applicant: P2 Science, Inc.

Inventor： Patrick FOLEY ,  Yonghua YANG

IPC: C07C29/147

CPC classification number: C07C29/147 ,  C07C29/36 ,  C07C33/025

Abstract: The invention relates to terpene-derived compounds, such as acids, esters thereof, produced by ozonolysis of terpenes, and to alcohols, amides, nitriles derived therefrom, as well as to processes for synthesizing them. Specifically, 2,3,7-trimethyloct-6-en-2-ol, 2,3,7-trimethyloct-7-en-2-ol, or a mixture thereof, produced by Grignard reaction of a terpene derived carboxylate with methyl magnesium bromide is disclosed.