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公开(公告)号:US20180086685A1
公开(公告)日:2018-03-29
申请号:US15567666
申请日:2016-04-19
CPC分类号: C07C43/135 , B01J31/38 , C07C41/01 , C07C41/26 , C07C41/30 , C07C43/1783 , C07C43/1785 , C07C43/23 , C07F7/003 , C08F10/00 , C08F10/02 , C08F110/06 , C08F210/06 , C08F210/16 , C08F4/025 , C08F4/64193
摘要: Disclosed are novel bridged bi-aromatic phenol ligands and transition metal compounds derived therefrom. Also disclosed are methods of making the ligands and transition metal compounds.
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公开(公告)号:US09802879B2
公开(公告)日:2017-10-31
申请号:US15317476
申请日:2015-06-17
发明人: Kenneth L. Matheson , Kip Sharp , Teresa L. Marino , Shane F. Cutrer , Allan B. Hauser , Tamra R. Weemes , Steve C. Lyons , Geoffrey Russell , Qisheng Wu , Harald Kohnz , Ollie M. James , Cecil C. Mercy , Herbert Olin Perkins
CPC分类号: C07C41/03 , B01J31/0202 , B01J31/0204 , B01J31/0212 , C07C43/1785
摘要: A process of preparing an alkoxylation catalyst wherein a catalyst precursor which is formed from an alkoxylated alcohol, calcium hydroxide, carboxylic acid, inorganic acid, and propylene oxide, is mixed with an antioxidant, preferably butylated hydroxyl toluene. A process of alkoxylation using the catalyst of the present invention.
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公开(公告)号:US09708251B2
公开(公告)日:2017-07-18
申请号:US14395829
申请日:2013-03-13
申请人: Stepan Company
发明人: David R. Allen , Marcos Alonso , Mary Beddaoui , Randal J. Bernhardt , Aaron Brown , Xue Min Dong , Wilma Gorman , John Hutchison , Gary Luebke , Renee Luka , Franz Luxem , Andrew D. Malec , Ronald A Masters , Dennis S Murphy , Patti Skelton , Brian Sook , Chris Spaulding , Michael Wiester , Patrick Shane Wolfe
IPC分类号: A61K47/00 , C07C309/10 , C11D1/14 , C11D1/29 , A01N25/30 , A61K8/46 , B01F17/00 , C04B38/10 , C07C29/147 , C07C303/14 , C07C303/32 , C07C309/08 , C11D1/37 , C07C41/06 , C09D7/12 , C11D1/66 , C07C41/03
CPC分类号: C07C309/10 , A01N25/30 , A61K8/463 , A61K8/466 , A61K2800/10 , B01F17/0057 , B01F17/0092 , C04B38/10 , C07C29/147 , C07C41/03 , C07C41/06 , C07C303/14 , C07C303/32 , C07C309/08 , C09D7/63 , C11D1/143 , C11D1/146 , C11D1/29 , C11D1/37 , C11D1/66 , A01N37/34 , A01N43/40 , A01N43/56 , A01N43/653 , A01N43/70 , A01N47/30 , A01N51/00 , C07C43/1785 , C07C33/025
摘要: Unsaturated fatty alcohol alkoxylates, processes for making them, and methods of using them are disclosed. In one aspect, a monounsaturated fatty alcohol alkoxylate is made by reducing a metathesis-derived monounsaturated alkyl ester, followed by alkoxylation of the resulting monounsaturated alcohol. Microscopy reveals that the monounsaturated alkoxylates have isotropic and lamellar phases over a wider range of actives levels compared with their saturated analogs. This attribute expands formulating latitude for many end-use applications. The unsaturated fatty alcohol alkoxylates are valuable in, for example, agricultural solvents, nonionic emulsifiers for agricultural compositions, hard surface cleaners, laundry detergents, specialty foams, additives or surfactants for paints or coatings, and surfactant compositions for enhanced oil recovery.
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公开(公告)号:US08501715B2
公开(公告)日:2013-08-06
申请号:US13085542
申请日:2011-04-13
申请人: Dror Harats , Jacob George , Gideon Halperin , Itzhak Mendel , Niva Yacov , Eti Kovalevski-Ishai
发明人: Dror Harats , Jacob George , Gideon Halperin , Itzhak Mendel , Niva Yacov , Eti Kovalevski-Ishai
CPC分类号: C07F9/106 , A61K31/075 , A61K31/08 , A61K31/11 , A61K31/19 , A61K31/20 , A61K31/215 , A61K31/225 , A61K31/24 , A61K31/685 , C07C43/13 , C07C43/1785 , C07C43/1787 , C07F9/10 , Y02A50/411 , Y02A50/414
摘要: Novel synthetic oxidized lipids and methods utilizing oxidized lipids for treating and preventing an inflammation associated with an endogenous oxidized lipid are provided.
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公开(公告)号:US07902176B2
公开(公告)日:2011-03-08
申请号:US10567543
申请日:2004-05-27
申请人: Dror Harats , Jacob George , Gideon Halperin , Niva Yacov , Eti Kovalevski-Ishai
发明人: Dror Harats , Jacob George , Gideon Halperin , Niva Yacov , Eti Kovalevski-Ishai
CPC分类号: C07F9/106 , A61K31/075 , A61K31/08 , A61K31/11 , A61K31/19 , A61K31/20 , A61K31/215 , A61K31/225 , A61K31/24 , A61K31/685 , C07C43/13 , C07C43/1785 , C07C43/1787 , C07F9/10 , Y02A50/411 , Y02A50/414
摘要: Novel synthetic oxidized lipids and methods utilizing oxidized lipids for treating and preventing an inflammation associated with an endogenous oxidized lipid are provided.
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公开(公告)号:US20070037103A1
公开(公告)日:2007-02-15
申请号:US11460326
申请日:2006-07-27
申请人: Kiyoshi FUKUSAKA , Osamu ISHIGE , Takeshi KURATA
发明人: Kiyoshi FUKUSAKA , Osamu ISHIGE , Takeshi KURATA
IPC分类号: G03C1/00
CPC分类号: G03C1/49827 , C07C39/16 , C07C39/17 , C07C43/1785 , C07C65/105 , C07C69/007 , C07C69/78 , C07C69/96 , C07C2601/14
摘要: A photothermographic material is disclosed, comprising on at least one side of a support a light-sensitive layer containing a light-sensitive silver halide and a light-insensitive organic silver salt, wherein the photothermographic material further comprises at least a reducing agent represented by the following formula (1):
摘要翻译: 公开了一种光热敏成像材料,其在载体的至少一侧上包含含有感光卤化银和不光敏有机银盐的感光层,其中所述光热敏成像材料还包含至少一种由 以下公式(1):
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公开(公告)号:US20050215830A1
公开(公告)日:2005-09-29
申请号:US10516026
申请日:2002-06-07
申请人: Yasumi Shimizu , Kaoru Nakao , Tohru Matsutomi
发明人: Yasumi Shimizu , Kaoru Nakao , Tohru Matsutomi
IPC分类号: C07C41/16 , C07C43/15 , C07C43/178 , C07C41/03
CPC分类号: C07C41/16 , C07C43/15 , C07C43/1785
摘要: In the production of allyl ethers of polyol by reacting a straight-chain polyol compound with an allyl halide in the presence of an alkali metal hydroxide, wherein the straight-chain polyol compound has carbon atoms each having one hydroxyl group, the reaction between the straight-chain polyol compound and the allyl halide is proceeded in the presence of water having the amount dissolving the straight-chain polyol compound at a reaction temperature, then 14% by mol, based on total molar amount of a hydroxyl group contained in the straight-chain polyol compound, of the allyl halide is added to a reaction system before at least part of water is released out of the reaction system.
摘要翻译: 在碱金属氢氧化物存在下,通过使直链多元醇化合物与烯丙基卤化物反应制备多元醇的烯丙基醚,其中直链多元醇化合物具有各自具有一个羟基的碳原子,直链 链状多元醇化合物和烯丙基卤化物在反应温度下在直链多元醇化合物的溶解量存在下进行,然后以直链状多元醇化合物中所含的羟基的总摩尔量为14摩尔% 在将至少部分水从反应体系中排出之前,将烯丙基卤的链多元醇化合物加入到反应体系中。
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公开(公告)号:US20030225035A1
公开(公告)日:2003-12-04
申请号:US10445347
申请日:2003-05-27
发明人: Dror Harats , Jacob George , Gideon Halperin
IPC分类号: A61K031/685 , C07F009/02
CPC分类号: C07F9/106 , A61K31/075 , A61K31/08 , A61K31/11 , A61K31/19 , A61K31/20 , A61K31/215 , A61K31/225 , A61K31/24 , A61K31/685 , C07C43/13 , C07C43/1785 , C07C43/1787 , C07F9/10 , Y02A50/411 , Y02A50/414
摘要: Novel synthetic forms of etherified oxidized phospholipids and methods of utilizing same for preventing and treating atherosclerosis and other related disorders, as well as inflammatory disorders, immune mediated diseases, autoimmune diseases and proliferative disorders, are provided. In addition, methods of synthesizing etherified and esterified oxidized phospholipids and of using same for preventing and treating atherosclerosis and other related disorders are also provided.
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公开(公告)号:US5723456A
公开(公告)日:1998-03-03
申请号:US662623
申请日:1996-06-13
IPC分类号: C07D487/22 , A61K31/00 , A61K31/40 , A61K31/407 , A61P3/00 , A61P3/06 , A61P3/10 , A61P9/00 , A61P9/10 , A61P9/12 , A61P13/00 , A61P43/00 , C07C43/174 , C07C43/178 , C07D498/22 , C07D513/22 , C07F7/18 , A61K31/55
CPC分类号: C07C43/1745 , A61K31/407 , C07C43/1785 , C07D487/22 , C07D498/22 , C07D513/22 , C07F7/1852
摘要: A method for treating endothelial cell dysfunction, such as associated with cardiovascular disease are disclosed, particularly using the isozyme selective PKC inhibitor, (S)-3,4-�N,N'-1,1'-((27"-ethoxy)-3'"(O)-4'"-(N,N-dimethylamino)-butane)-bis-(3,3'-indolyl)!-1(H)-pyrrole-2,5-dione hydrochloride salt.
摘要翻译: 公开了一种用于治疗内皮细胞功能障碍的方法,例如与心血管疾病相关的方法,特别是使用同功酶选择性PKC抑制剂(S)-3,4- [N,N'-1,1' - ((27“ 乙氧基)-3“(O)-4” - (N,N-二甲基氨基) - 丁烷) - 双(3,3'-吲哚基)] - 1(H) - 吡咯-2,5- 二盐酸盐。
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公开(公告)号:US5541347A
公开(公告)日:1996-07-30
申请号:US317140
申请日:1994-10-03
IPC分类号: C07C43/174 , C07C43/178 , C07D487/22 , C07D498/22 , C07D513/22 , C07F7/18 , C07C41/03
CPC分类号: C07D487/22 , C07C43/1745 , C07C43/1785 , C07D498/22 , C07D513/22 , C07F7/1852
摘要: The present invention provides a novel synthesis of the compounds of Formula (I): ##STR1## The compounds are produced in high yield and without utilizing expensive chromatographic separations. The synthesis is particularly advantageous because it is stereoselective.
摘要翻译: 本发明提供式(I)化合物的新合成:(I)化合物以高产率生产,不需要昂贵的色谱分离。 合成是特别有利的,因为它是立体选择性的。
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