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公开(公告)号：US06790204B2
公开(公告)日：2004-09-14
申请号：US10419912
申请日：2003-04-15
IPC分类号： A61M3100
CPC分类号： A61M25/008 , A61B17/22 , A61B2017/22067 , A61B2017/22084 , A61B2217/005 , A61M25/0071 , A61M25/1011 , A61M2025/0081 , A61M2025/0183 , A61M2025/1052 , A61M2210/0693
摘要： A method for the treatment of a stenosis or an occlusion in a blood vessel is disclosed in which a main catheter is first delivered to a site proximal to the occlusion. The main catheter may include an occlusive device at its distal end. An inner catheter or elongate member (e.g., a guidewire) having an occlusive device at its distal end is delivered to the site of the occlusion, and the occlusive device is activated at a site distal to the occlusion. A therapy catheter is then introduced to treat the occlusion. Next, a catheter is delivered just proximal to the occlusive device, and this catheter is used to aspirate and/or irrigate the area removing particles and debris. The aspiration and irrigation steps are preferably repeated until the particles and debris are removed. Perfusion may be performed by using a perfusion-filter distal of the lesion to be treated or a hypotube which extends beyond the occlusive device attached to the guidewire. The present invention provides for a minimally invasive procedure which can be performed quickly and efficiently, with reduced risks to the patient.
摘要翻译： 公开了一种用于治疗血管狭窄或闭塞的方法，其中主导管首先被输送到接近闭塞的部位。 主导管可以在其远端处包括闭塞装置。 在其远端具有闭塞装置的内导管或细长构件（例如，导丝）被输送到闭塞部位，并且闭塞装置在远端闭塞位置被激活。 然后引入治疗导管以治疗闭塞。 接下来，将导管刚好靠近闭塞装置输送，并且该导管用于抽吸和/或冲洗除去颗粒和碎屑的区域。 优选重复抽吸和冲洗步骤，直到除去颗粒和碎屑。 灌注可以通过使用待治疗的病变的远侧的灌注过滤器或延伸超过连接到导丝线的闭塞装置的海波管来进行。 本发明提供了可以快速有效地执行并降低患者风险的微创手术。
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公开(公告)号：US06669670B1
公开(公告)日：2003-12-30
申请号：US09712407
申请日：2000-11-13
申请人： Ketan P. Muni , Jeffrey C. Bleam
发明人： Ketan P. Muni , Jeffrey C. Bleam
IPC分类号： A61M5178
CPC分类号： A61M25/104 , A61M25/09 , A61M25/09033 , A61M2025/09175 , A61M2025/1093 , C22F1/006
摘要： Disclosed herein is an improved core wire for use in a medical catheter. In one aspect, a tapering core wire is incorporated into the distal end of a catheter. The catheter has a tubular body. Both ends of an inflatable balloon are mounted to the tubular body. The core wire extends from the distal end of the tubular body. In one embodiment, substantially all of the taper of the core wire occurs in the extending portion of the core wire over a length of at least 15 mm but no more than 60 mm. In another aspect, a core wire with a shapeable tip and method of manufacturing the same are provided. A core wire previously made superelastic is subject to additional processing to remove its superelasticity thereby allowing the material to be shapeable to aid in advancing the core wire through a blood vessel or other body cavities. In another aspect of the present invention, a method is provided for securing the core wire to the distal end of an elongated catheter tubular body. The tubular body is mechanically crimped onto the core wire to secure the core wire in place. This crimping method has been found to increase the strength of the bond between the core wire and the catheter tube so that greater pull force is required to break the core wire off from the catheter.
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公开(公告)号：US06652480B1
公开(公告)日：2003-11-25
申请号：US09438030
申请日：1999-11-10
IPC分类号： A61M100
CPC分类号： A61M25/104 , A61B17/22 , A61B18/245 , A61B2017/22067 , A61B2017/22084 , A61M2025/09183 , A61M2025/1015 , A61M2025/1052 , A61M2025/109 , A61M2025/1093
摘要： A method for reducing distal embolization during insertion of devices to treat plaque, thrombi and other intravascular occlusions. Using a guide catheter, a guidewire is delivered to a site proximal to the lesion. An aspiration catheter is then introduced over the guidewire, and the two are moved together in a distal to proximal direction across the occlusion. The aspiration catheter is then moved in a proximal to distal direction while continuously aspirating, which prevents embolization of any particles which may be created during the crossing of the guidewire.
摘要翻译： 一种用于在插入装置以治疗斑块，血栓和其他血管内闭塞的过程中减少远端栓塞的方法。 使用引导导管将导丝输送到病变附近的部位。 然后在引导线上引入抽吸导管，并且两者在跨近闭塞的远端到近端方向一起移动在一起。 然后将抽吸导管沿近端方向移动，同时连续抽吸，这可以防止在导线交叉期间产生的任何颗粒的栓塞。
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公开(公告)号：US06468230B2
公开(公告)日：2002-10-22
申请号：US10035706
申请日：2001-12-21
IPC分类号： A61B500
CPC分类号： C22F1/006 , A61M25/09 , A61M2025/09175 , A61M2025/1093
摘要： The present invention provides an improved core wire for use in a medical catheter. In one aspect, the invention provides a core wire with a shapeable tip and method of using the same. A core wire previously made superelastic is subject to additional processing to remove its superelasticity thereby allowing the material to be shapeable to aid in advancing the core wire through a blood vessel or other body cavities. In another aspect of the present invention, a method is provided for securing the core wire to the distal end of an elongated catheter tubular body. The tubular body is mechanically crimped onto the core wire to secure the core wire in place. This crimping method has been found to increase the strength of the bond between the core wire and the catheter tube so that greater pull force is required to break the core wire off from the catheter.
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公开(公告)号：US06375628B1
公开(公告)日：2002-04-23
申请号：US09505380
申请日：2000-02-16
IPC分类号： A61B500
CPC分类号： A61M25/10 , A61M25/09 , A61M2025/09008 , A61M2025/09141 , A61M2025/09175 , A61M2025/09183 , A61M2025/1052
摘要： The present invention provides an apparatus for performing angioplasty or vascular intervention procedures. The apparatus of the present invention comprises a catheter apparatus comprised of a superelastic hollow guidewire, a balloon member and a flexible tip. The superelastic hollow guidewire of the invention is preferably a hypotube of nitinol alloy. The use of nitinol alloy as hollow guidewire provides a catheter apparatus having high flexibility and torqueability as well as small cross sectional diameter.
摘要翻译： 本发明提供一种用于进行血管成形术或血管介入手术的装置。 本发明的装置包括由超弹性中空导丝，球囊构件和柔性尖端构成的导管装置。 本发明的超弹性中空导丝优选为镍钛合金的海波管。 使用镍钛诺合金作为中空导线提供了具有高柔性和可逆性以及小截面直径的导管装置。
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公开(公告)号：US06312407B1
公开(公告)日：2001-11-06
申请号：US09026106
申请日：1998-02-19
IPC分类号： A61M2900
CPC分类号： A61B17/12022 , A61B17/12036 , A61B17/12109 , A61B17/12168 , A61B17/12172 , A61B17/22 , A61B2017/1205 , A61B2017/22067 , A61F2/01 , A61F2002/011 , A61F2002/016 , A61F2002/018 , A61F2230/0006 , A61F2230/005 , A61F2230/0065 , A61F2230/0069 , A61F2230/0076 , A61F2230/008 , A61F2230/0091 , A61M25/0009 , A61M25/0026 , A61M25/0054 , A61M25/0075 , A61M25/09 , A61M25/09033 , A61M25/10 , A61M25/1011 , A61M25/10182 , A61M29/02 , A61M2025/0018 , A61M2025/0079 , A61M2025/09008 , A61M2025/09116 , A61M2025/09125 , A61M2025/09175 , A61M2025/1015 , A61M2025/1045 , A61M2025/1052 , A61M2025/1079 , A61M2025/1081 , A61M2025/1093
摘要： A device for occluding a vessel employs one of a number of different expansion members joined to one or more elongate members. The expansion member may include a braid, one or more coils, ribs, a ribbon-like structure, a slotted tube, or a filter-like mesh. If the expansion member is enclosed by a suitable membrane, the device seals with the vessel wall to partially or completely occlude the vessel. A perforated membrane may be used to permit the perfusion of blood. The expansion member may be self-expanding, or it may be expanded by engaging it with one of the elongate members. Alternatively, the expansion member may be expanded by heating it.
摘要翻译： 用于封闭容器的装置采用与一个或多个细长构件连接的多个不同的膨胀构件中的一个。 膨胀构件可以包括编织物，一个或多个线圈，肋，带状结构，开槽管或过滤器状网。 如果膨胀构件被合适的膜封闭，则装置与容器壁密封以部分地或完全地封闭容器。 穿孔膜可用于允许血液灌注。 膨胀构件可以是自膨胀的，或者可以通过使其与细长构件之一接合而膨胀。 或者，可以通过加热来膨胀膨胀构件。
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公开(公告)号：US6117106A
公开(公告)日：2000-09-12
申请号：US419614
申请日：1999-10-14
CPC分类号： A61M25/104 , A61M25/0052 , A61M2025/0004 , A61M2025/1079 , A61M2025/1097 , A61M25/0053
摘要： A perfusion dilatation catheter is disclosed which has an improved distal catheter shaft portion with a tubular member extending within the balloon provided with an expanded coil support incorporated within the wall of the tubular member. The coil is preferably closer to the inner surface than the outer surface of the tubular member. Also disclosed are improved catheter shaft sections in a perfusion portion proximal to the balloon, one with a reinforced inflation tube depending into the guidewire lumen and another having three separate lumens, a central guidewire lumen and a pair of inflation lumens on opposing sides of the tubular structure defining the guidewire lumen.
摘要翻译： 公开了一种灌注扩张导管，其具有改进的远端导管轴部分，其具有在球囊内延伸的管状构件，该管状构件设置有并入管状构件的壁内的扩张的线圈支架。 线圈优选地比管状构件的外表面更靠近内表面。 还公开了在靠近气囊的灌注部分中的改进的导管轴部分，一个具有依赖于导丝管腔的增强的充气管，另一个具有三个独立的腔，中心导丝腔和一对在管的相对侧上的充气腔 限定导丝管腔的结构。
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公开(公告)号：US5849846A
公开(公告)日：1998-12-15
申请号：US476101
申请日：1995-06-06
申请人： Ziyun Chen , Tai C. Cheng , Jeong S. Lee , Ketan P. Muni , Udayan Patel , Robert P. Saltman
发明人： Ziyun Chen , Tai C. Cheng , Jeong S. Lee , Ketan P. Muni , Udayan Patel , Robert P. Saltman
IPC分类号： A61L29/00 , A61L29/04 , A61M25/00 , A61M25/16 , C08L23/02 , C08L67/00 , C08L67/02 , C08L77/00 , A61M25/10 , A61M29/02
CPC分类号： A61L29/049 , A61M25/1029 , C08L67/02 , A61M2025/1031 , A61M25/0009
摘要： A catheter and/or balloon for a medical catheter is formed from a blend of polymeric components, including a first crystalline polymeric component and a second softening polymeric component. The polymeric material can also include a third compatibilizing agent to facilitate blending the first two polymeric components together. The first polymeric component can be a polyester or a polyamide, and the second polymeric component can be a polyolefin, or an ethylene copolymer. The third polymeric component is preferably an ethylene copolymer containing a reactive group that forms a covalent bond with the first polymeric component. The polymeric material forming the balloon or catheter also can include a catalyst to catalyze a reaction between the compatibilizing ethylene copolymer and the second polymer component. The second, softening polymeric component can also include a silane coupling agent, to provide a reactive softening copolymer that bonds with the first strong polymeric component, to provide increased flexibility of catheters and balloons formed from the polymeric components. The properties of the balloon and catheter formed from the polymeric material can be enhanced by crosslinking by irradiation of the polymeric material.
摘要翻译： 用于医疗导管的导管和/或气囊由聚合物组分的混合物形成，包括第一结晶聚合物组分和第二软化聚合物组分。 聚合物材料还可以包括第三相容剂以便于将前两个聚合物组分共混在一起。 第一聚合物组分可以是聚酯或聚酰胺，第二聚合物组分可以是聚烯烃或乙烯共聚物。 第三聚合物组分优选是含有与第一聚合物组分形成共价键的反应性基团的乙烯共聚物。 形成气囊或导管的聚合物材料还可以包括催化剂，以催化相容性乙烯共聚物和第二聚合物组分之间的反应。 第二软化聚合物组分还可以包括硅烷偶联剂，以提供与第一强聚合物组分键合的反应性软化共聚物，以提供由聚合物组分形成的导管和气囊的增加的柔性。 由聚合物材料形成的球囊和导管的性质可以通过聚合材料的照射交联来增强。
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公开(公告)号：US5348537A
公开(公告)日：1994-09-20
申请号：US913859
申请日：1992-07-15
申请人： Steven P. Wiesner , Ketan P. Muni
发明人： Steven P. Wiesner , Ketan P. Muni
CPC分类号： A61M25/0075 , A61M25/104 , A61M2025/0063
摘要： A sealing element for dilatation and other inflatable catheters which is formed of a polymer matrix having a bearing surface and having incorporated, at least in the portion of the matrix forming the bearing surface, a lubricous material which swells upon contact with an aqueous based liquid. The bearing surface is adapted to engage the surface of a movable member such as a guidewire when the bearing surface expands from contact with aqueous based liquid. This engagement seals the interface between the movable member and the sealing element and prevents the passage of significant amounts of liquid through the interface between these elements.
摘要翻译： 用于膨胀的密封元件和其它可充气导管，其由具有支承表面的聚合物基体形成，并且至少在形成支承表面的基质部分中并入润滑材料，所述润滑材料在与基于水的液体接触时溶胀。 当轴承表面与基于水的液体的接触膨胀时，支承表面适于接合诸如导丝的可移动部件的表面。 该接合密封可移动构件和密封元件之间的界面，并防止大量液体通过这些元件之间的界面。
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80.发明授权公开(公告)号：US09095646B2
公开(公告)日：2015-08-04
申请号：US13550293
申请日：2012-07-16
申请人： Mina W. B. Chow , Hung V. Ha , Ketan P. Muni , Eric A. Goldfarb
发明人： Mina W. B. Chow , Hung V. Ha , Ketan P. Muni , Eric A. Goldfarb
IPC分类号： A61M31/00 , A61M3/02 , A61B17/24 , A61M25/10 , A61M29/00 , A61B17/34 , A61B17/16 , A61B19/00 , A61B17/00
CPC分类号： A61M3/0295 , A61B17/1688 , A61B17/24 , A61B17/3478 , A61B90/39 , A61B2017/00557 , A61B2217/007 , A61M3/0283 , A61M25/10 , A61M29/00 , A61M2210/0681
摘要： A medical device, and a system and packaged kit containing the medical device for the treatment of a sinus opening is described. The medical device comprises a proximal end, a distal end, and a shaft system having an inflation lumen and an irrigation lumen the proximal and. The shaft system has a proximal shaft section and a distal shaft section. An inflatable balloon is attached to the distal shaft section in a position that is proximal to said distal end. The irrigation tip is distal to the balloon on the distal shaft section and has a tip opening and one or more radially facing openings. A method for treating a sinus opening includes inserting a system that includes the medical device, a sinus guide catheter and a sinus guide element into a patient's anatomy, dilating the sinus opening and irrigating a target in the nasal anatomy.
摘要翻译： 描述了一种医疗装置，以及包含用于治疗窦开口的医疗装置的系统和包装工具。 医疗装置包括近端，远端以及具有充气腔和冲洗腔的远端和远端的轴系。 轴系具有近轴部分和远侧轴部分。 可膨胀气球在远端轴部分附近位于靠近所述远端的位置。 冲洗尖端在远侧轴部分上的球囊的远侧，并且具有尖端开口和一个或多个径向面对的开口。 用于治疗窦口的方法包括将包括医疗装置的系统，窦导管和窦引导元件插入患者的解剖结构中，扩张鼻窦开口并冲洗鼻解剖结构中的靶。
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