公开(公告)号：US07817280B2

公开(公告)日：2010-10-19

申请号：US12626577

申请日：2009-11-25

申请人： Benjamin D. Pless

发明人： Benjamin D. Pless

IPC分类号： G01B9/02

CPC分类号： G06K9/2036 ,  G06K9/00577

摘要： Disclosed are a method and system for performing device identification and a medical device susceptible to identification using interference patterns for performing device identification. A source signal may be directed from an energy source towards the surface of a device for reflection therefrom. An interference pattern may be detected from the surface of the device, such as by a sensor. A determination as to whether a match exists between the representation of the interference pattern and a stored representation of an interference pattern may be performed. If a match exists, the device may be identified based on the stored representation of the interference pattern. Otherwise, a representation of the interference pattern may be stored and a unique identifier may be assigned to the stored representation of the interference pattern.

摘要翻译： 公开了用于执行设备识别的方法和系统以及易于使用用于执行设备识别的干扰图案的识别的医疗设备。 源信号可以从能量源朝向装置的表面引导以从其反射。 可以从设备的表面（例如通过传感器）检测干涉图案。 可以执行关于在干涉图案的表示和存储的干涉图案的表示之间是否存在匹配的确定。 如果存在匹配，则可以基于存储的干涉图案的表示来识别该设备。 否则，可以存储干扰图案的表示，并且可以将唯一标识符分配给所存储的干涉图案的表示。

公开(公告)号：US06597954B1

公开(公告)日：2003-07-22

申请号：US09724805

申请日：2000-11-28

申请人： Benjamin D. Pless ,  Robert E. Fischell ,  David R. Fischell

发明人： Benjamin D. Pless ,  Robert E. Fischell ,  David R. Fischell

IPC分类号： A61N136

CPC分类号： A61N1/0529 ,  A61B5/0002 ,  A61B5/0476 ,  A61B5/4094 ,  A61B5/7217 ,  A61M5/14276 ,  A61N1/0534 ,  A61N1/36064 ,  A61N1/36082 ,  G06F19/00

摘要： A system and method for controlling epilepsy and other neurological disorders by providing electrical stimulation to a patient's brain in response to detected neurological conditions. An implantable device includes a stimulation subsystem coupled to a stimulation electrode to provide responsive electrical brain stimulation in response to an event detected via an on-board processor's analysis of data received from a detection subsystem coupled to a detection electrode located in a different portion of the patient's brain.

摘要翻译： 一种通过响应于检测到的神经病症向患者的大脑提供电刺激来控制癫痫和其他神经障碍的系统和方法。 可植入装置包括耦合到刺激电极的刺激子系统，以响应于经由车载处理器对从耦合到位于所述第二部分的不同部分的检测电极的检测子系统接收的数据的分析而检测的事件来响应电脑刺激 病人的大脑

公开(公告)号：US06473639B1

公开(公告)日：2002-10-29

申请号：US09517797

申请日：2000-03-02

申请人： David R. Fischell ,  Jonathan Harwood ,  Benjamin D. Pless

发明人： David R. Fischell ,  Jonathan Harwood ,  Benjamin D. Pless

IPC分类号： A61B500

CPC分类号： A61B5/4094 ,  A61B5/0476 ,  A61N1/36017 ,  A61N1/36064 ,  A61N1/37235

摘要： This invention relates generally to information processing techniques used in the treatment of epilepsy and to devices for using these techniques.

摘要翻译： 本发明一般涉及用于治疗癫痫的信息处理技术以及使用这些技术的装置。

公开(公告)号：US5983472A

公开(公告)日：1999-11-16

申请号：US969074

申请日：1997-11-12

申请人： Timothy A. Fayram ,  Benjamin D. Pless ,  Scott McCall ,  Craig Mar

发明人： Timothy A. Fayram ,  Benjamin D. Pless ,  Scott McCall ,  Craig Mar

IPC分类号： A61N1/39 ,  H01G7/00 ,  H01G4/38

CPC分类号： A61N1/3956 ,  H01G9/008 ,  H01G9/08 ,  Y10T29/417 ,  Y10T29/43 ,  Y10T29/435 ,  Y10T29/49789

摘要： A method of manufacturing a capacitor for use in an implantable cardiac defibrillator by forming a set of conductive sheets with the same profile having a sacrificial portion. An alignment figure is formed in each sheet, and the sheets are stacked and aligned by registering the alignment figures with each other. The sacrificial portions are removed from each of the sheets, which are secured together and positioned in a capacitor housing. Each sheet may include two major portions joined by the sacrificial portion, so that each major portion may become part of a separate capacitor stack after the sacrificial portion is removed, doubling manufacturing throughput.

摘要翻译： 一种用于制造用于可植入心脏除颤器的电容器的方法，通过形成具有相同轮廓的一组导电片材具有牺牲部分。 在每个片材中形成对准图，并且通过将对准图彼此对准来堆叠和对准片材。 牺牲部分从固定在一起并定位在电容器壳体中的每个片材中移除。 每个片材可以包括由牺牲部分连接的两个主要部分，使得在牺牲部分被去除之后，每个主要部分可以成为单独的电容器堆叠的一部分，使制造生产量翻倍。

公开(公告)号：US5542173A

公开(公告)日：1996-08-06

申请号：US388766

申请日：1995-02-15

申请人： Craig E. Mar ,  Benjamin D. Pless ,  M. Elizabeth Bush

发明人： Craig E. Mar ,  Benjamin D. Pless ,  M. Elizabeth Bush

IPC分类号： A61N1/04 ,  A61N1/05 ,  H01R43/00

CPC分类号： A61N1/0563 ,  Y10T29/49117

摘要： An implantable defibrillator lead comprises a flexible core onto which is wound helically wound coils to form an electrode. These electrode coils are partially encapsulated by a flexible matrix which holds them in their wrapped position around the core. Due to its coiled coil structure, this electrode provides improved flexibility, and can be used endocardially, intravascularly, epicardially, or subcutaneously. The electrode may function alternately as a defibrillation electrode and as a sensing electrode in a lead with a separate pacing electrode.

摘要翻译： 可植入除颤器引线包括柔性芯，绕线圈缠绕在其上以形成电极。 这些电极线圈被柔性矩阵部分封装，将它们保持在围绕芯的缠绕位置。 由于其螺旋线圈结构，该电极提供改善的柔性，并且可以在心内膜，血管内，心外膜或皮下使用。 电极可以作为除颤电极交替地起作用，并且作为具有单独的起搏电极的引线中的感测电极。

公开(公告)号：US5531765A

公开(公告)日：1996-07-02

申请号：US275852

申请日：1994-07-15

申请人： Benjamin D. Pless

发明人： Benjamin D. Pless

IPC分类号： A61N1/39

CPC分类号： A61N1/3956 ,  A61N1/3906 ,  A61N1/3912

摘要： A programmable implantable medical device utilizable for delivering a configurable defibrillation waveform to a patient's heart. The device includes defibrillation electrode means adapted to be connected to the heart for delivering a multiphasic defibrillation waveform thereto. A programmable waveform generator connected to the heart generates the biphasic waveform such that the first phase of the defibrillation waveform has programmed tilt and the second phase has a duration which is a function of the duration of the first phase.

摘要翻译： 一种可编程可植入医疗装置，其可用于将可配置的除颤波形传送至患者的心脏。 所述装置包括适于连接到心脏的除颤电极装置，用于向其递送多相除颤波形。 连接到心脏的可编程波形发生器产生双相波形，使得除颤波形的第一相位具有编程倾斜，并且第二相位具有作为第一相持续时间的函数的持续时间。

公开(公告)号：US5489293A

公开(公告)日：1996-02-06

申请号：US221343

申请日：1994-03-31

申请人： Benjamin D. Pless ,  Rose A. Province

发明人： Benjamin D. Pless ,  Rose A. Province

IPC分类号： A61N1/39

CPC分类号： A61N1/3956 ,  A61N1/3912 ,  A61N1/3987

摘要： The present invention provides an apparatus and method for cardiac defibrillation which utilizes a lower voltage defibrillation output to depolarize the myocardial cells by providing a rapid sequence of defibrillation shocks synchronized with sensed sequential cardiac events or features during an arrhythmia. Each shock may be a conventional monophasic or biphasic pulse. Each of the shocks may be relatively short in duration, i.e. on the order of 0.5 to 3 milliseconds or may be relatively long, i.e. up to about 100 milliseconds. The amplifiers of the sensing circuitry are particularly adapted quickly recover to after each shock is delivered to allow synchronization of the next shock to the next cardiac feature. This is accomplished by using broad band amplifiers which have DC-baseline restoration capability in order to eliminate offsets caused by a preceding shock. A microprocessor in the pulse generator delivers a programmed number of pulses synchronized to the ECG. If a first sequence fails to terminate the arrhythmia, another sequence is delivered at a higher voltage and/or additional pulses are added to the sequence.

摘要翻译： 本发明提供一种用于心脏除颤的装置和方法，其利用较低电压除颤输出来通过在心律失常期间提供与感测的顺序心脏事件或特征同步的快速顺序的除颤休克来去极化心肌细胞。 每次冲击可能是常规的单相或双相脉冲。 每个冲击的持续时间可能相对较短，即在0.5至3毫秒的量级，或者可能相对较长，即高达约100毫秒。 感测电路的放大器特别适合于在每次电击被输送之后快速恢复以允许下一次震动与下一个心脏特征的同步。 这是通过使用具有直流基线恢复能力的宽带放大器来实现的，以便消除由先前的冲击引起的偏移。 脉冲发生器中的微处理器传送与心电图同步的编程数量的脉冲。 如果第一序列不能终止心律失常，则在较高电压下递送另一个序列，和/或将附加脉冲加到序列中。

公开(公告)号：US5447518A

公开(公告)日：1995-09-05

申请号：US114574

申请日：1993-08-31

申请人： Benjamin D. Pless

发明人： Benjamin D. Pless

IPC分类号： A61N1/39

CPC分类号： A61N1/3956 ,  A61N1/3912 ,  A61N1/3987

摘要： An implantable cardioverter/defibrillator and method for its use. A sensing electrode provides an ECG signal to the defibrillator, this signal is amplified and evaluated for the presence of a tachyarrhythmia. The phase of the ECG signal is sensed during a detected fibrillation or tachycardia and this determines the phase of the stimulating output signals. The ECG may be continuously sensed during the application of the defibrillating output and each output is held constant until a threshold crossing of the ECG is detected, whereupon the defibrillating output is changed. The system may also be configured to generate outputs in response to the ECG signal exceeding one or more thresholds. The defibrillating output is generated as a constant current output. The ECG amplifier compensates for a resultant offset voltage with an autozero loop. The specific lead configuration and the patient's condition are considered in programming the amplitude and polarity of the defibrillation output. In an alternative embodiment, the phase of the ECG signal is detected and an output of predetermined duration is delivered. In this configuration, it is not necessary to sense the ECG during the output. The system may also be used in a preconditioning mode wherein the phase related output is followed by a conventional high voltage monophasic or biphasic defibrillation waveform. The ECG is monitored for return to normal rhythm and the output stimulation is discontinued when normal rhythm is restored.

摘要翻译： 一种植入式心律转复除颤器及其使用方法。 感测电极向除颤器提供ECG信号，该信号被放大并评估是否存在快速性心律失常。 在检测到的原纤维化或心动过速期间感测ECG信号的相位，并且这确定了刺激输出信号的相位。 可以在施加去纤颤输出期间连续感测ECG，并且每个输出保持恒定，直到检测到ECG的阈值交叉，从而改变除颤输出。 该系统还可被配置为响应于超过一个或多个阈值的ECG信号而产生输出。 除颤输出产生为恒定电流输出。 ECG放大器利用自动调零回路补偿合成偏移电压。 在对除颤输出的幅度和极性进行编程时，考虑了具体的引线配置和患者状况。 在替代实施例中，检测ECG信号的相位并传送预定持续时间的输出。 在该配置中，在输出期间不需要感测ECG。 该系统还可以以预处理模式使用，其中相位相关输出之后是传统的高电压单相或双相除颤波形。 监测ECG以恢复正常的节律，并且当恢复正常节律时输出刺激被停止。

公开(公告)号：US5439485A

公开(公告)日：1995-08-08

申请号：US126619

申请日：1993-09-24

申请人： Craig E. Mar ,  Benjamin D. Pless ,  M. Elizabeth Bush

发明人： Craig E. Mar ,  Benjamin D. Pless ,  M. Elizabeth Bush

IPC分类号： A61N1/04 ,  A61N1/05 ,  A61N1/36

CPC分类号： A61N1/0563 ,  Y10T29/49117

摘要： An implantable defibrillator lead comprises a flexible core onto which is wound helically wound coils to form an electrode. These electrode coils are partially encapsulated by a flexible matrix which holds them in their wrapped position around the core. Due to its coiled coil structure, this electrode provides improved flexibility, and can be used endocardially, intravascularly, epicardially, or subcutaneously. The electrode may function alternately as a defibrillation electrode and as a sensing electrode in a lead with a separate pacing electrode.

摘要翻译： 可植入除颤器引线包括柔性芯，绕线圈缠绕在其上以形成电极。 这些电极线圈被柔性矩阵部分封装，将它们保持在围绕芯的缠绕位置。 由于其螺旋线圈结构，该电极提供改善的柔性，并且可以在心内膜，血管内，心外膜或皮下使用。 电极可以作为除颤电极交替地起作用，并且作为具有单独的起搏电极的引线中的感测电极。

公开(公告)号：US5025172A

公开(公告)日：1991-06-18

申请号：US476932

申请日：1990-02-08

申请人： Kenneth J. Carroll ,  Benjamin D. Pless

发明人： Kenneth J. Carroll ,  Benjamin D. Pless

IPC分类号： A61N1/39 ,  H03H19/00

CPC分类号： A61N1/3931 ,  H03H19/004

摘要： An implantable cardiac defibrillator employing a switched capacitor filter stage having charge steering resistors connected in series with corresponding switched capacitors that are coupled to a sensitive node of an operational amplifier. The stored channel charges in associated switches when they are tuned off are directed away from the sensitive node. The switches associated with the switched capacitors are operated by control signals having a generally trapezoidal shaped waveform so as to slowly turn off the same, thereby reducing clock feedthrough and charge injection induced offset voltage on the output of the operational amplifier.

摘要翻译： 一种可植入心脏除颤器，其采用开关电容器滤波器级，其具有与耦合到运算放大器的敏感节点的相应开关电容器串联连接的电荷转向电阻器。 相关交换机关闭时存储的信道费用远离敏感节点。 与开关电容器相关联的开关由具有大致梯形波形的控制信号操作，以便缓慢关闭开关电容器，从而减少运算放大器的输出端上的时钟馈通和电荷注入引起的失调电压。