公开(公告)号：US08049439B2

公开(公告)日：2011-11-01

申请号：US12363607

申请日：2009-01-30

申请人： Bin Zhao ,  Jack W. Cornish ,  Brian B. Horng ,  Victor K. Lee ,  Andrew M. Kameya

发明人： Bin Zhao ,  Jack W. Cornish ,  Brian B. Horng ,  Victor K. Lee ,  Andrew M. Kameya

IPC分类号： H05B37/02

CPC分类号： H05B33/0815 ,  H05B33/0827 ,  Y02B20/347

摘要： A voltage source provides an output voltage to drive a plurality of light emitting diode (LED) strings. A LED driver adjusts the level of the output voltage so as to maintain the lowest tail voltage of the LED strings at or near a predetermined threshold voltage so as provide sufficient headroom voltages for current regulators for the LED strings. The LED driver operates in an operational mode and a calibration mode, which can be implemented in parallel with, or part of, the operational mode. During the calibration mode, the LED driver determines, for each LED string, a code value representative of the level of the output voltage necessary to maintain the tail voltage of the corresponding LED string at or near the predetermined threshold voltage. In the operational mode, the code values from the calibration mode are used to control the voltage source to provide an appropriate level for the output voltage.

摘要翻译： 电压源提供输出电压以驱动多个发光二极管（LED）串。 LED驱动器调节输出电压的电平，以便将LED串的最低尾电压保持在预定阈值电压处或接近预定阈值电压，以便为LED串的电流调节器提供足够的净空电压。 LED驱动器在操作模式和校准模式下操作，其可以与操作模式并行或部分实现。 在校准模式期间，LED驱动器针对每个LED串确定代表将相应LED串的尾部电压维持在或接近预定阈值电压所需的输出电压电平的代码值。 在操作模式下，来自校准模式的代码值用于控制电压源以为输出电压提供适当的电平。

公开(公告)号：US08035315B2

公开(公告)日：2011-10-11

申请号：US12340985

申请日：2008-12-22

申请人： Bin Zhao ,  Jack W. Cornish ,  Brian B. Horng ,  Andrew M. Kameya ,  Jan Krellner ,  Kenneth C. Kwok ,  Victor K. Lee ,  Weizhuang W. Xin

发明人： Bin Zhao ,  Jack W. Cornish ,  Brian B. Horng ,  Andrew M. Kameya ,  Jan Krellner ,  Kenneth C. Kwok ,  Victor K. Lee ,  Weizhuang W. Xin

IPC分类号： H05B37/02 ,  G09G5/00

CPC分类号： H05B33/0818 ,  H05B33/0827 ,  H05B33/0851

摘要： Power management in a light emitting diode (LED) system having a plurality of LED strings is disclosed. A voltage source provides an output voltage to drive a plurality of LED strings. An LED driver implements a feedback mechanism to monitor the tail voltages of the active LED strings to identify the minimum tail voltage and adjust the output voltage of the voltage source based on the lowest tail voltage. A loop calibration module of the LED driver calibrates the feedback mechanism of the LED driver based on a relationship between a digital code value used to generate a particular output voltage and another digital code value generated based on the minimum tail voltage resulting from the particular output voltage.

摘要翻译： 公开了具有多个LED串的发光二极管（LED）系统中的电源管理。 电压源提供输出电压以驱动多个LED串。 LED驱动器实现反馈机制来监测有源LED串的尾部电压以识别最小尾电压，并且基于最低的尾部电压来调节电压源的输出电压。 LED驱动器的回路校准模块基于用于产生特定输出电压的数字代码值与基于由特定输出电压产生的最小尾部电压产生的另一数字代码值之间的关系来校准LED驱动器的反馈机制 。

公开(公告)号：US07843242B1

公开(公告)日：2010-11-30

申请号：US12537692

申请日：2009-08-07

申请人： Bin Zhao

发明人： Bin Zhao

IPC分类号： H03K3/017

CPC分类号： G06F1/025 ,  H03K5/15013 ,  H03K7/08

摘要： A pulse width modulation (PWM) signal generator generates multiple output PWM signals from an input PWM signal, whereby each output PWM signal has a frequency and duty ratio substantially similar to the input PWM signal and each output PWM signal is phase-shifted in relation to the other output PWM signals. The PWM signal generator samples a PWM cycle of the input PWM signal to determine various PWM parameters representative of the duration of the active portion of the sampled PWM cycle and the total duration of the sampled PWM cycle. The PWM signal generator then uses the PWM parameters to generate corresponding PWM cycles for the output PWM signals using a set of two independent counters. This process of sampling a PWM cycle of the input PWM signal and generating the output PWM signals based on the PWM parameters resulting from the sampling process can be repeated for one or more iterations.

摘要翻译： 脉冲宽度调制（PWM）信号发生器从输入PWM信号产生多个输出PWM信号，由此每个输出PWM信号的频率和占空比基本上类似于输入的PWM信号，并且每个输出PWM信号相对于 另外输出PWM信号。 PWM信号发生器对输入PWM信号的PWM周期进行采样，以确定表示采样PWM周期的有效部分的持续时间和采样PWM周期的总持续时间的各种PWM参数。 PWM信号发生器然后使用PWM参数来使用一组两个独立计数器为输出PWM信号产生相应的PWM周期。 对采样过程产生的PWM参数进行采样输入PWM信号的PWM周期并产生输出PWM信号的过程可重复进行一次或多次迭代。

公开(公告)号：US20100201279A1

公开(公告)日：2010-08-12

申请号：US12690972

申请日：2010-01-21

申请人： Bin Zhao

发明人： Bin Zhao

IPC分类号： H05B37/02

CPC分类号： H05B33/0818 ,  H05B33/0857

摘要： A light emitting diode (LED) system implements a power management technique. The LED system includes a plurality of LED drivers connected in series, each LED driver configured to regulate the current flowing through a corresponding subset of a plurality of LED strings. Each LED driver determines the tail voltages of the one or more LED strings of the corresponding subset. Each LED driver, except for the first LED driver in the series, also receives a voltage representative of the minimum tail voltage of the other subsets regulated by the upstream LED drivers. Each LED driver then provides the lowest of the voltage received from the upstream LED driver and the one or more tail voltages of the corresponding subset to the downstream LED driver. In this manner a voltage representative of the minimum tail voltage of the plurality of LED strings is cascaded through the series. A feedback controller monitors the minimum tail voltage represented by this cascaded voltage and accordingly adjusts an output voltage provided to the head ends of the plurality of LED strings.

摘要翻译： 发光二极管（LED）系统实现电源管理技术。 LED系统包括串联连接的多个LED驱动器，每个LED驱动器配置成调节流过多个LED串的相应子集的电流。 每个LED驱动器确定相应子集的一个或多个LED串的尾部电压。 除了该系列中的第一个LED驱动器之外，每个LED驱动器还接收代表由上游LED驱动器调节的其他子集的最小尾电压的电压。 然后，每个LED驱动器将从上游LED驱动器接收的最低电压和相应子集的一个或多个尾部电压提供给下游LED驱动器。 以这种方式，表示多个LED串的最小尾电压的电压通过该系列级联。 反馈控制器监视由该级联电压表示的最小尾电压，并相应地调节提供给多个LED串的头端的输出电压。

公开(公告)号：US07713709B2

公开(公告)日：2010-05-11

申请号：US11724983

申请日：2007-03-16

申请人： Joleen White ,  Lisa Argento Flay ,  Erik Foehr ,  Gary Taniguchi ,  William S. Prince ,  Bin Zhao

发明人： Joleen White ,  Lisa Argento Flay ,  Erik Foehr ,  Gary Taniguchi ,  William S. Prince ,  Bin Zhao

IPC分类号： G01N33/53

CPC分类号： G01N33/6854 ,  G01N33/573 ,  G01N2333/924

摘要： The present invention relates to methods for screening body fluids or tissues for antibodies, including neutralizing and isotype-specific antibodies, against lysosomal enzymes administered as part of enzyme replacement therapy.

摘要翻译： 本发明涉及用于针对作为酶替代疗法的一部分而施用的溶酶体酶筛选用于抗体的体液或组织的方法，包括中和和同种型特异性抗体。

公开(公告)号：US20090315481A1

公开(公告)日：2009-12-24

申请号：US12363294

申请日：2009-01-30

申请人： Bin Zhao

发明人： Bin Zhao

IPC分类号： H05B37/02

CPC分类号： H05B33/0815 ,  H05B33/0857

摘要： Disclosed are example open channel detection techniques at a light emitting diode (LED) driver of an LED system. The LED driver does not enable its LED channels before normal operation so as to inhibit current flow through the LED channels during start-up. While the LED channels are disabled, the LED driver compares the voltages at the LED channel inputs with a predetermined voltage to determine whether an operational LED string of an associated LED panel is connected to the LED channel. In the event that an LED channel is determined to be an “open” channel, the LED driver further disables the LED channel for the following normal operational mode. Otherwise, if the LED channel is determined to be connected to an operational LED string, the LED driver enables the LED channel for the normal operational mode, during which the LED channel can be selectively activated for light output subject to display data for the LED panel.

摘要翻译： 公开了LED系统的发光二极管（LED）驱动器处的示例性开放通道检测技术。 LED驱动器在正常操作之前不能使能其LED通道，以便在启动期间禁止通过LED通道的电流。 当LED通道被禁用时，LED驱动器将LED通道输入端的电压与预定电压进行比较，以确定相关LED面板的工作LED串是否连接到LED通道。 在LED通道确定为“开路”通道的情况下，LED驱动器进一步禁用LED通道用于以下正常操作模式。 否则，如果LED通道被确定为连接到可操作的LED串，则LED驱动器使得LED通道能够进入正常操作模式，在此期间LED通道可以选择性地激活以进行LED输出的显示数据 。

公开(公告)号：US07584370B2

公开(公告)日：2009-09-01

申请号：US11473351

申请日：2006-06-22

申请人： Bin Zhao

发明人： Bin Zhao

IPC分类号： G06F1/26 ,  H03K17/00

CPC分类号： H03K19/018557 ,  H03K17/063 ,  H03K17/102 ,  H03K17/687

摘要： A semiconductor network is interposed between first and second multiple-port interfaces each having high-voltage, intermediate-voltage and ground ports to form a switch assembly. The assembly includes a primary switch circuit, a support network, internal and external-port circuits and internal and external-port control circuits. The primary switch circuit is coupled to high-voltage ports of the multiple-port interfaces and to the support network. The internal and external-port circuits are coupled to intermediate-voltage ports of the multiple-port interfaces, the internal and external-port control circuits and the support network. The internal-port control circuit is coupled to the internal-port circuit, the support network and a ground port of a first multiple-port interface. The external-port control circuit is coupled to the external-port circuit, the support network and a ground port of the second multiple-port interface. The assembly has a low-leakage current in both open and closed states when exposed to a range of high voltages.

摘要翻译： 半导体网络介于第一和第二多端口接口之间，每个端口具有高电压，中间电压和接地端口以形成开关组件。 组件包括主开关电路，支撑网络，内部和外部端口电路以及内部和外部端口控制电路。 主开关电路耦合到多端口接口的高压端口和支持网络。 内部和外部端口电路耦合到多端口接口的中压端口，内部和外部端口控制电路和支持网络。 内部端口控制电路耦合到内部端口电路，支持网络和第一多端口接口的接地端口。 外部端口控制电路耦合到外部端口电路，支持网络和第二多端口接口的接地端口。 当暴露于一定范围的高电压时，组件在打开和关闭状态都具有低漏电流。

公开(公告)号：US20070279023A1

公开(公告)日：2007-12-06

申请号：US11448651

申请日：2006-06-06

申请人： Bin Zhao

发明人： Bin Zhao

IPC分类号： G05F1/00

CPC分类号： H02M3/07

摘要： According to one exemplary embodiment, a voltage up-conversion circuit includes a modulated voltage generator circuit, where the modulated voltage generator circuit is configured to receive an input voltage and generate a modulated voltage, and where the modulated voltage generator circuit includes at least one transistor. The voltage up-conversion circuit further includes a switching circuit coupled to the modulated voltage generator circuit, where the switching circuit is configured to couple the modulated voltage to a load capacitor when the modulated voltage is at a high level and decouple the modulated voltage to the load capacitor when the modulated voltage is at a low level. In the voltage up-conversion circuit, the load capacitor reaches a voltage greater a breakdown voltage of the at least one transistor in the modulated voltage generator circuit. The breakdown voltage can be a reliability breakdown voltage.

摘要翻译： 根据一个示例性实施例，电压上变换电路包括调制电压发生器电路，其中调制电压发生器电路被配置为接收输入电压并产生调制电压，并且其中调制电压发生器电路包括至少一个晶体管 。 电压上变换电路还包括耦合到调制电压发生器电路的开关电路，其中开关电路被配置为当调制电压处于高电平时将调制电压耦合到负载电容器，并将调制电压去耦到 当调制电压处于低电平时加载电容。 在电压上变换电路中，负载电容器达到调制电压发生器电路中至少一个晶体管的击穿电压更大的电压。 击穿电压可以是可靠性击穿电压。

公开(公告)号：US20050086556A1

公开(公告)日：2005-04-21

申请号：US10987245

申请日：2004-11-12

申请人： Min Zhu ,  Bin Zhao

发明人： Min Zhu ,  Bin Zhao

IPC分类号： H04L1/22 ,  H04L29/06 ,  H04L29/08 ,  H04L29/14 ,  G06F15/16

CPC分类号： H04L1/22 ,  H04L67/1002 ,  H04L67/1008 ,  H04L67/1012 ,  H04L67/1029 ,  H04L67/1031 ,  H04L69/40

摘要： A distributed collaborative computer system is provided that comprises a plurality of server computers interconnected via a high-speed link. Client computers can connect to any available server computer and start or join a conference hosted on either the server computer to which the client computer is connected or any other server in the system. As a result, the system and method of the present invention is easily scalable to support an arbitrary number of participants to a conference by merely adding the appropriate number of server computers to the system. In addition, by replicating the conference information on more than one server computer, the single point of failure limitation is eliminated. In fact, if a server hosting or participating in a conference malfunctions, the failure is detected by other server computers and the client computer is able to reconnect to the conference through a new server computer.

摘要翻译： 提供了一种分布式协同计算机系统，其包括通过高速链路互连的多个服务器计算机。 客户端计算机可以连接到任何可用的服务器计算机，并启动或加入在与客户端计算机连接的服务器计算机或系统中的任何其他服务器上托管的会议。 结果，本发明的系统和方法可以容易地扩展，以通过仅仅将适当数量的服务器计算机添加到系统来支持会议的任意数量的参与者。 另外，通过在多台服务器计算机上复制会议信息，消除了单点故障限制。 事实上，如果托管或参与会议的服务器发生故障，则其他服务器计算机检测到故障，客户端计算机能够通过新的服务器计算机重新连接到会议。

公开(公告)号：US20050013869A1

公开(公告)日：2005-01-20

申请号：US10622316

申请日：2003-07-18

申请人： Cheng Chaw ,  Yi-Yan Yang ,  Shabbir Moochhala ,  Donna Tan ,  Bin Zhao

发明人： Cheng Chaw ,  Yi-Yan Yang ,  Shabbir Moochhala ,  Donna Tan ,  Bin Zhao

IPC分类号： A61K9/16 ,  A61K9/22 ,  A61K9/50

CPC分类号： A61K9/1647

摘要： The invention provides microparticles for sustained release formulation for physostigmine, pyridostigmine and other therapeutically active carbamates. The microparticles comprise the active compound and a biodegradable polymer such as polyester, poly(phosphate), poly(anhydride), poly(ortho ester), or mixture thereof. In one embodiment, the polymer is poly(d,l-lactide-co-glycolide). The desired release pattern of the active compound may be readily attained by varying the type and amount of the polymer used, including by using a mixture of two polymers, one of which is more hydrophobic. The invention also provides a method of preparing the microparticles and in one embodiment, the microparticles may be prepared by spray drying.

摘要翻译： 本发明提供用于毒扁豆黄素，吡斯的明和其他治疗活性氨基甲酸酯的持续释放制剂的微粒。 微粒包括活性化合物和可生物降解的聚合物如聚酯，聚（磷酸酯），聚（酸酐），聚（原酸酯）或其混合物。 在一个实施方案中，聚合物是聚（d，l-丙交酯 - 共 - 乙交酯）。 通过改变所用聚合物的类型和量可以容易地获得所需的活性化合物的释放模式，包括通过使用两种聚合物的混合物，其中一种是更疏水的。 本发明还提供了制备微粒的方法，在一个实施方案中，微粒可以通过喷雾干燥制备。