Antibodies to human carboxypeptidase B and methods of use thereof
    73.
    发明授权
    Antibodies to human carboxypeptidase B and methods of use thereof 失效
    人类羧肽酶B的抗体及其使用方法

    公开(公告)号:US5474901A

    公开(公告)日:1995-12-12

    申请号:US277540

    申请日:1994-07-19

    摘要: A novel polypeptide, designated plasma carboxypeptidase B (PCPB), has been purified from human plasma. It has been cloned from a human liver cDNA library using PCR amplification. Provided herein is nucleic acid encoding PCPB useful in diagnostics and in the recombinant preparation of PCPB. PCPB is used in the preparation and purification of antibodies thereto, in the purification of plasminogen, in the inhibition of plasminogen activation by t-PA in the presence of fibrinogen, and in diagnostic assays.

    摘要翻译: 已经从人血浆中纯化了一种称为血浆羧肽酶B(PCPB)的新型多肽。 使用PCR扩增从人肝cDNA文库克隆。 本文提供了编码PCPB的核酸,其可用于诊断和PCPB的重组制备。 PCPB用于制备和纯化其中的纤维蛋白溶酶原的抗体,在纤维蛋白原存在下通过t-PA抑制纤溶酶原激活,以及在诊断测定中。

    Plasma carboxypeptidase
    74.
    发明授权
    Plasma carboxypeptidase 失效
    血浆羧肽酶

    公开(公告)号:US5364934A

    公开(公告)日:1994-11-15

    申请号:US167727

    申请日:1993-12-15

    摘要: A novel polypeptide, designated plasma carboxypeptidase B (PCPB), has been purified from human plasma. It has been cloned from a human liver cDNA library using PCR amplification. Provided herein is nucleic acid encoding PCPB useful in diagnostics and in the recombinant preparation of PCPB. PCPB is used in the preparation and purification of antibodies thereto, in the purification of plasminogen, in the inhibition of plasminogen activation by t-PA in the presence of fibrinogen, and in diagnostic assays.

    摘要翻译: 已经从人血浆中纯化了一种称为血浆羧肽酶B(PCPB)的新型多肽。 使用PCR扩增从人肝cDNA文库克隆。 本文提供了编码PCPB的核酸,其可用于诊断和PCPB的重组制备。 PCPB用于制备和纯化其中的纤维蛋白溶酶原的抗体,在纤维蛋白原存在下通过t-PA抑制纤溶酶原激活,以及在诊断测定中。

    Human plasma carboxypeptidase B
    75.
    发明授权
    Human plasma carboxypeptidase B 失效
    人血浆羧肽酶B

    公开(公告)号:US5206161A

    公开(公告)日:1993-04-27

    申请号:US649591

    申请日:1991-02-01

    摘要: A novel polypeptide, designated plasma carboxypeptidase B (PCPB), has been purified from human plasma. It has been cloned from a human liver cDNA library using PCR amplification. Provided herein is nucleic acid encoding PCPB useful in diagnostics and in the recombinant preparation of PCPB. PCPB is used in the preparation and purification of antibodies thereto, in the purification of plasminogen, in the inhibition of plasminogen activation by t-PA in the presence of fibrinogen, and in diagnostic assays.

    摘要翻译: 已经从人血浆中纯化了一种称为血浆羧肽酶B(PCPB)的新型多肽。 使用PCR扩增从人肝cDNA文库克隆。 本文提供了编码PCPB的核酸,其可用于诊断和PCPB的重组制备。 PCPB用于制备和纯化其中的纤维蛋白溶酶原的抗体,在纤维蛋白原存在下通过t-PA抑制纤溶酶原激活,以及在诊断测定中。