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    NEURAL STIMULATION SYSTEM PROVIDING AUTO ADJUSTMENT OF STIMULUS OUTPUT AS A FUNCTION OF SENSED IMPEDANCE
    77.
    发明申请
    NEURAL STIMULATION SYSTEM PROVIDING AUTO ADJUSTMENT OF STIMULUS OUTPUT AS A FUNCTION OF SENSED IMPEDANCE 审中-公开
    神经刺激系统提供刺激输出的自动调整作为感测阻抗的功能

    公开(公告)号：US20100262209A1

    公开(公告)日：2010-10-14

    申请号：US12783187

    申请日：2010-05-19

    申请人： John D.H. King ,  James R. Thacker

    发明人： John D.H. King ,  James R. Thacker

    IPC分类号： A61N1/36

    CPC分类号： A61N1/36139 ,  A61N1/08 ,  A61N1/36071 ,  A61N1/3615

    摘要： A neural stimulation system automatically corrects or adjusts the stimulus magnitude (stimulation energy) in order to maintain a comfortable and effective stimulation therapy. Because the changes in impedance associated with the electrode-tissue interface can indicate obstruction of current flow and positional lead displacement, lead impedance can indicate the quantity of electrical stimulation energy that should be delivered to the target neural tissue to provide corrective adjustment. Hence, a change in impedance or morphology of an impedance curve may be used in a feedback loop to indicate that the stimulation energy needs to be adjusted and the system can effectively auto correct the magnitude of stimulation energy to maintain a desired therapeutic effect.

    摘要翻译： 神经刺激系统自动校正或调整刺激量（刺激能量），以保持舒适有效的刺激疗法。 由于与电极 - 组织界面相关的阻抗变化可以指示电流和位置引线位移的阻塞，所以引线阻抗可以指示应该传送到目标神经组织的电刺激能量的量以提供校正调整。 因此，可以在反馈回路中使用阻抗曲线的阻抗或形态的变化，以指示需要调整刺激能量，并且系统能够有效地自动校正刺激能量的大小以维持所需的治疗效果。

    SYSTEM AND METHOD FOR DETERMINING APPROPRIATE STEERING TABLES FOR DISTRIBUTING STIMULATION ENERGY AMONG MULTIPLE NEUROSTIMULATION ELECTRODES
    78.
    发明申请
    SYSTEM AND METHOD FOR DETERMINING APPROPRIATE STEERING TABLES FOR DISTRIBUTING STIMULATION ENERGY AMONG MULTIPLE NEUROSTIMULATION ELECTRODES 审中-公开
    用于确定多个神经网络电极分布刺激能量的适当转向表的系统和方法

    公开(公告)号：US20100121409A1

    公开(公告)日：2010-05-13

    申请号：US12614942

    申请日：2009-11-09

    申请人： Sridhar Kothandaraman ,  Carla Mann Woods ,  Kerry Bradley ,  James R. Thacker ,  Sivakumar Karnati

    发明人： Sridhar Kothandaraman ,  Carla Mann Woods ,  Kerry Bradley ,  James R. Thacker ,  Sivakumar Karnati

    IPC分类号： A61N1/08

    CPC分类号： A61N1/37247 ,  A61N1/36071 ,  A61N1/36157 ,  A61N1/36185 ,  A61N1/37264

    摘要： A method, computer medium, and system for programming a control device are provided. The control device is configured for controlling electrical stimulation energy provided to a plurality of electrode leads that are physically implanted within a patient in a side-by-side lead configuration. Electrical energy is conveying from the electrode leads to create a stimulation region within the patient. The stimulation region is automatically shifted along the electrode leads (e.g., by selecting and using at least one navigation table) in accordance with an electrical current shifting pattern that is based on a stagger of the side-by-side lead configuration. At least one stimulation parameter set is selected based on the effectiveness of the shifted stimulation region, and the control device is programmed with the selected stimulation parameter set(s).

    摘要翻译： 提供了一种用于编程控制装置的方法，计算机介质和系统。 控制装置被配置为用于控制提供给以并排引线配置物理地植入患者体内的多个电极引线的电刺激能量。 电能从电极引线输送以在患者体内产生刺激区域。 刺激区域沿着电极引线自动移位（例如，通过选择和使用至少一个导航表），该电流移动模式是基于并排引线配置的交错。 基于移位的刺激区域的有效性来选择至少一个刺激参数集合，并且使用所选择的刺激参数集编程控制装置。

    Apparatus and method for determining the relative position and orientation of neurostimulation leads
    79.
    发明授权
    Apparatus and method for determining the relative position and orientation of neurostimulation leads 有权
    用于确定神经刺激导联的相对位置和取向的装置和方法

    公开(公告)号：US07684869B2

    公开(公告)日：2010-03-23

    申请号：US11342989

    申请日：2006-01-30

    申请人： Kerry Bradley ,  James R. Thacker

    发明人： Kerry Bradley ,  James R. Thacker

    IPC分类号： A61N1/00

    CPC分类号： A61N1/08 ,  A61B5/053 ,  A61N1/0551

    摘要： Interelectrode impedance or electric field potential measurements are used to determine the relative orientation of one lead to other leads in the spinal column or other body/tissue location. Interelectrode impedance is determined by measuring impedance vectors. The value of the impedance vector is due primarily to the electrode-electrolyte interface, and the bulk impedance between the electrodes. The bulk impedance between the electrodes is, in turn, made up of (1) the impedance of the tissue adjacent to the electrodes, and (2) the impedance of the tissue between the electrodes. In one embodiment, the present invention makes both monopolar and bipolar impedance measurements, and then corrects the bipolar impedance measurements using the monopolar measurements to eliminate the effect of the impedance of the tissue adjacent the electrodes. The orientation and position of the leads may be inferred from the relative minima of the corrected bipolar impedance values. These corrected impedance values may also be mapped and stored to facilitate a comparison with subsequent corrected impedance measurement values. Such comparison allows a determination to be made as to whether the lead position and/or orientation has changed appreciably over time. In another embodiment, one or more electrodes are stimulated and the resulting electric field potential on the non-stimulated electrodes is measured. Such field potential measurements provide an indication of the relative orientation of the electrodes. Once known, the relative orientation may be used to track lead migration, to setup stimulation configurations and parameters for nominal stimulation and/or navigation. Also, such measurements allow automatic adjustment of stimulation energy to a previously-defined optimal potential field in the case of lead migration or postural changes.

    摘要翻译： 使用内电极阻抗或电场电位测量来确定一个引线与脊柱或其他身体/组织位置中的其它引线的相对取向。 内部电阻阻抗通过测量阻抗矢量来确定。 阻抗矢量的值主要是由于电极 - 电解质界面和电极之间的体阻抗。 电极之间的体阻抗又由（1）与电极相邻的组织的阻抗，和（2）电极之间的组织的阻抗构成。 在一个实施例中，本发明进行单极性和双极性阻抗测量，然后使用单极测量来校正双极性阻抗测量，以消除邻近电极的组织的阻抗的影响。 引线的取向和位置可以从校正的双极性阻抗值的相对最小值推断。 这些校正的阻抗值也可以被映射和存储，以便于与随后校正的阻抗测量值进行比较。 这样的比较允许确定引导位置和/或取向是否随时间明显变化。 在另一个实施例中，刺激一个或多个电极，并且测量未受激电极上产生的电场电位。 这种场电位测量提供了电极的相对取向的指示。 一旦知道，相对取向可用于跟踪引线迁移，设置用于标称刺激和/或导航的刺激配置和参数。 此外，这样的测量允许在铅迁移或姿势变化的情况下将刺激能量自动调整到先前定义的最佳势场。

    SYSTEM AND METHOD OF RAPID, COMFORTABLE PARAMETER SWITCHING IN SPINAL CORD STIMULATION
    80.
    发明申请
    SYSTEM AND METHOD OF RAPID, COMFORTABLE PARAMETER SWITCHING IN SPINAL CORD STIMULATION 有权
    系统和方法快速，舒适的参数切换在脊髓刺激

    公开(公告)号：US20090281599A1

    公开(公告)日：2009-11-12

    申请号：US12506827

    申请日：2009-07-21

    申请人： James R. Thacker ,  John D.H. King ,  Kerry Bradley

    发明人： James R. Thacker ,  John D.H. King ,  Kerry Bradley

    IPC分类号： A61N1/08

    CPC分类号： A61N1/36071 ,  A61N1/0551

    摘要： A system and method for rapidly switching stimulation parameters of a Spinal Cord Stimulation (SCS) system increases the number of stimulation parameter sets that may be tested during a fitting procedure, or alternatively, reduces the time required for the fitting procedure. The switching method comprises selecting a new stimulation parameter set, and setting the initial stimulation levels to levels at or just below an estimated perception threshold of the patient. The estimated perception level is based on previous stimulation results. The stimulation level is then increased to determine a minimum stimulation level for effective stimulation, and/or an optimal stimulation level, and/or a maximum stimulation level, based on patient perception.

    摘要翻译： 用于快速切换脊髓刺激（SCS）系统的刺激参数的系统和方法增加了在拟合过程期间可以测试的刺激参数集的数量，或者替代地减少了拟合过程所需的时间。 切换方法包括选择新的刺激参数集合，以及将初始刺激水平设置为等于或低于估计的患者感知阈值的水平。 估计的感知水平是基于以前的刺激结果。 然后根据患者的感知，增加刺激水平以确定有效刺激的最小刺激水平和/或最佳刺激水平和/或最大刺激水平。