公开(公告)号：US20070161969A1

公开(公告)日：2007-07-12

申请号：US10587507

申请日：2005-01-28

Applicant: Erik Andersen

Inventor： Erik Andersen

IPC: A61M39/10 ,  A61M39/00 ,  A61M25/16 ,  A61M25/18

CPC classification number: A61M25/00 ,  A61M25/0113 ,  A61M25/02 ,  A61M25/09041 ,  A61M39/06 ,  A61M2025/09125

Abstract: A device for securing one or more guide wires (112,114) or intravascular catheters in relation to a connector (100) of a haemostatic valve assembly as used for example in angioplasty, comprises a frame with a body portion (120) and holders (130;132) for securing the connector in relation to the body portion. A locking mechanism secures the one or more guide wires or catheters in relation to the frame when the guide wires or catheters extend through the connector, the guide wires or catheters being intended to guide balloon catheters and/or stents to an artery treatment site. In one embodiment, the locking mechanism comprises two slidable members (142;144) for pressing the guide wires or catheters against an abutment surface, which may be flexible to provide a secure securing of the guide wires or catheters. Alternatively, there may be provided spring-biased or eccentrically, rotationally mounted locking members.

Abstract translation: 用于例如在血管成形术中使用的用于固定一个或多个导丝（112,114）或血管内导管相对于止血阀组件的连接器（100）的装置包括具有主体部分（120）和支架（130; 132），用于相对于主体部分固定连接器。 当导丝或导管穿过连接器延伸时，锁定机构相对于框架固定一个或多个导丝或导管，导丝或导管旨在将球囊导管和/或支架引导到动脉治疗部位。 在一个实施例中，锁定机构包括用于将引导线或导管压靠在邻接表面上的两个可滑动构件（142; 144），该邻接表面可以是柔性的，以提供引导线或导管的牢固固定。 或者，可以提供弹簧偏置或偏心的，旋转地安装的锁定构件。

公开(公告)号：US20050069896A1

公开(公告)日：2005-03-31

申请号：US10661398

申请日：2003-09-12

Applicant: H. Horvitz ,  Craig Ceol ,  Erik Andersen

Inventor： H. Horvitz ,  Craig Ceol ,  Erik Andersen

IPC: A01K67/00 ,  A61K20060101 ,  C07K14/47 ,  C07K16/18 ,  C12N1/00 ,  C12N5/10 ,  C12N15/11 ,  C12N15/12 ,  C12N15/63 ,  C12Q1/02 ,  C12Q1/68 ,  G01N33/00 ,  G01N33/574

CPC classification number: C07K14/47

Abstract: In general, the invention provides methods and compositions useful in the treatment of a neoplasia. These compositions include new components of the Rb pathway that function in chromatin remodeling and antagonize Ras signaling.

Abstract translation: 通常，本发明提供了可用于治疗瘤形成的方法和组合物。 这些组合物包括在染色质重塑和拮抗Ras信号传导中起作用的Rb通路的新成分。

公开(公告)号：US20050027249A1

公开(公告)日：2005-02-03

申请号：US10842848

申请日：2004-05-11

Applicant: Nikolaus Reifart ,  Erik Andersen ,  John Abele ,  Sandra Tartaglino ,  Timothy Wheeler

Inventor： Nikolaus Reifart ,  Erik Andersen ,  John Abele ,  Sandra Tartaglino ,  Timothy Wheeler

IPC: A61M29/02 ,  A61M29/00

CPC classification number: A61M25/104 ,  A61M2025/0063 ,  A61M2025/0183 ,  A61M2025/1079

Abstract: A stiffenable balloon catheter assembly capable of being converted from an “over-the-wire” mode with respect to a guidewire extending therethrough to a “rapid-exchange” mode with respect to a guidewire extending therethrough, and vice versa. The catheter has a plurality of lumens, one lumen however, having a side opening with an obstructable galp, the orientation of which, determines the utilization “mode” of the catheter assembly. Stiffening stylets may be adjustably locked into the lumens, depending upon the “mode”, to control the stiffness of the catheter assembly during its utilization within a patient.

Abstract translation: 相对于延伸穿过其中的导丝线，相对于延伸穿过其的导丝线，可以从“线上”模式转换成“快速交换”模式的可加强气球导管组件，反之亦然。 导管具有多个管腔，但是，一个管腔具有一个具有阻塞性隆起的侧开口，其取向决定了导管组件的利用“模式”。 取决于“模式”，加强样式可以可调节地锁定到腔中，以在患者体内使用期间控制导管组件的刚度。

公开(公告)号：US20050002371A1

公开(公告)日：2005-01-06

申请号：US10795282

申请日：2004-03-09

Applicant: Erik Andersen

Inventor： Erik Andersen

IPC: H04L12/28 ,  H04L12/46 ,  H04L12/56

CPC classification number: H04L49/9021 ,  H04L47/10 ,  H04L47/15 ,  H04L47/21 ,  H04L49/90 ,  H04L49/9042 ,  H04L2012/5665

Abstract: A method of handling data in a memory of a network device is disclosed. The method includes the steps of storing portions of a datagram, being handled by a network device, in a memory, where the memory comprises two logic memory blocks, storing at least two pointers with the portions of the datagram in the memory, where one of the at least two pointers points to a next portion of the memory to be accessed, retrieving the portions of the datagram and the at least two pointers when the network device is ready to act on the datagram, polling a register to determine which of the at least two pointers actually points to the next portion, retrieving the next portion, when necessary and acting on the datagram based on the processing of the datagram by the network device.

Abstract translation: 公开了一种在网络设备的存储器中处理数据的方法。 该方法包括以下步骤：将由网络设备处理的数据报的部分存储在存储器中，其中存储器包括两个逻辑存储器块，将至少两个指针与数据报的部分存储在存储器中，其中， 所述至少两个指针指向要访问的存储器的下一部分，当所述网络设备准备好对所述数据报进行操作时，检索所述数据报的部分和所述至少两个指针，轮询寄存器以确定所述存储器中的哪一个 至少两个指针实际上指向下一部分，在必要时检索下一部分，并且基于网络设备对数据报的处理而对数据报进行操作。

公开(公告)号：US06542977B1

公开(公告)日：2003-04-01

申请号：US09607666

申请日：2000-06-30

Applicant: Erik Andersen

Inventor： Erik Andersen

IPC: G06F1202

CPC classification number: H04L49/9047 ,  H04L49/90

Abstract: A method and apparatus for combining cost effectiveness of data signal ports sharing a common memory storage device with reliable data signal communication of data signal ports each having a dedicated memory storage device. In one embodiment, data signals are received at a number of data signal ports of a data signal communication platform. A data signal bandwidth capability of a memory storage device of the data communication platform is determined. Once the data signal bandwidth capability of the memory storage device is determined, the memory storage device is segmented to improve utilization of the data signal bandwidth capability. As a result, cost effectiveness of data signal ports sharing a common memory storage device and reliability of data signal communication of data signal ports each having a dedicated memory storage device is combined.

公开(公告)号：US06511474B1

公开(公告)日：2003-01-28

申请号：US09614360

申请日：2000-07-12

Applicant: Erik Andersen

Inventor： Erik Andersen

IPC: A61J1500

CPC classification number: A61M25/0068 ,  A61J15/00 ,  A61J15/0007 ,  A61J15/0026 ,  A61M25/0069 ,  A61M25/007 ,  A61M2025/0073

Abstract: The present invention is a bolus for an enteral feeding tube, or catheter, that is capable of being used in an over-the-wire intubation procedure as well as other intubation procedures. The bolus has a generally tubular body defining a sidewall, a proximal end tube opening capable of being connected to a distal end of the enteral feeding tube, and a generally rounded terminal end having a flattened tip. The bolus includes a fluid opening within the sidewall of the bolus between the proximal end opening and the terminal end of the bolus. An interior surface of the sidewall opposite the fluid opening is curved and slopes upwardly toward a distal end of the fluid opening. The curved interior surface and the fluid opening configuration allows for fluid flow that approximates the fluid flow rate characteristics of an open-ended tube. The fluid opening is biased toward the terminal end of the bolus thereby defining an elongated collar portion adjacent the proximal end tube opening of the bolus. The terminal end of the bolus has an aperture therethrough that forms a stylet passage in communication with the fluid opening. The stylet passage is sized to allow a stylet to pass therethrough when the tube is used in an over-the-wire intubation procedure.

公开(公告)号：US06355070B1

公开(公告)日：2002-03-12

申请号：US09648245

申请日：2000-08-25

Applicant: Erik Andersen ,  Ernst Peter Strecker

Inventor： Erik Andersen ,  Ernst Peter Strecker

IPC: A61F206

CPC classification number: A61F2/90 ,  A61F2/0077 ,  A61F2/95 ,  A61F2/958 ,  A61F2002/046 ,  A61F2210/0019 ,  A61F2210/0076 ,  A61F2230/0013 ,  A61F2230/0078 ,  A61F2250/0039 ,  D04B1/225 ,  D10B2509/06 ,  Y10S623/902

Abstract: A stent for reinforcement of the lumen of a peristaltic organ is formed by knitting preferably a nitinol wire into a pattern of overlapping loops selected such that from a relaxed state each row of loops may shift axially relative to and independently of the rows on either side. This local lengthening and shortening accommodate peristalsis of the organ without migrating within the organ. A stent is also shown which comprises two resilient cylindrical mesh layers and a semi-permeable compliant membrane such as expanded polytetrafluoroethylene, sandwiched between. The two mesh layers may be knit of a flexible filament, and the knit may be configured so that the stent can adapt to peristalsis of the body lumen. A method is also shown of manufacturing a delivery system for a resilient tubular device such as a stent so that the device can be inserted into the body in a substantially reduced diameter. The method uses a confining block having a bore and a slot leading into the bore. The tubular device is pinched and inserted into the bore and the slot, two mandrels are inserted into the bore, one inside the device and one outside and the mandrels are revolved about each other to roll the device on itself.

Abstract translation: 用于加强蠕动器官腔的支架通过优选地将镍钛诺丝编织成选择的重叠环的图案形成，使得从松弛状态，每排环可以相对于且独立于任一侧的行而轴向移动。 这种局部延长和缩短容纳器官的蠕动，而不会在器官内迁移。 还示出了一种支架，其包括两个弹性圆柱形网眼层和夹在其间的半透性柔顺膜，例如膨胀聚四氟乙烯。 两个网眼层可以是柔性细丝的编织物，并且针织物可以被配置成使得支架能够适应体腔的蠕动。 还示出了制造用于诸如支架的弹性管状装置的输送系统的方法，使得该装置可以以基本上减小的直径插入到体内。 该方法使用具有孔的限制块和通向孔的槽。 管状装置被夹持并插入孔和槽中，两个心轴插入孔中，一个在装置内部和一个外部，并且心轴彼此旋转以在其自身上滚动装置。

公开(公告)号：US5931812A

公开(公告)日：1999-08-03

申请号：US808042

申请日：1997-03-04

Applicant: Erik Andersen ,  Ib Jorgensen

Inventor： Erik Andersen ,  Ib Jorgensen

IPC: A61M25/00 ,  A61M29/02 ,  A61M29/00

CPC classification number: A61M25/104 ,  A61M2025/0063 ,  A61M2025/0183

Abstract: The invention features a catheter having a stylet that increases columnar strength and axial force transmission ("pushability") of the catheter shaft. This aspect of the invention features the stylet extending distally beyond an exit port which is used in rapid catheter exchange and being embedded in the catheter shaft, there being a stress-transferring relationship between the exterior of the stylet and the substance defining the shaft at least in the vicinity of the exit port, the stylet with the embedded relationship increasing the columnar strength of the shaft in the region of the port and increasing the pushability of the catheter.

Abstract translation: 本发明的特征在于具有提高导管轴的柱状强度和轴向力传递（“推动性”）的探针的导管。 本发明的这个方面的特征在于，探针的远端延伸超过用于快速导管交换并且嵌入在导管轴中的出口，在探针的外部和至少限定轴的物质之间存在应力传递关系 在出口附近，具有嵌入关系的探针增加了在该区域中的轴的柱状强度并增加了导管的推动性。

公开(公告)号：US5833275A

公开(公告)日：1998-11-10

申请号：US346471

申请日：1994-11-29

Applicant: Erik Andersen

Inventor： Erik Andersen

IPC: F16L37/00 ,  F16L37/084 ,  F16L37/08

CPC classification number: A61M39/0247 ,  F16L37/008 ,  F16L37/084 ,  A61M2039/0261 ,  A61M2039/027 ,  A61M2039/0282 ,  A61M2039/0297 ,  A61M2039/1016 ,  A61M2039/1027 ,  A61M2039/1094 ,  A61M39/1011

Abstract: An apparatus for connecting tubing which comprises a connector body having an inner lumen and an outer surface, a connector sleeve having an inner surface which defines a passageway, at least a portion of the connector body insertable into the connector sleeve and the surfaces thereof in slidable engagement, a shoulder and a latch on the surfaces in slidable engagement, and the latch positioned to engage with the shoulder to lock the connector body inserted within the connector sleeve.

Abstract translation: 一种用于连接管道的装置，其包括具有内腔和外表面的连接器主体，连接器套筒，其具有限定通道的内表面，所述连接器主体的至少一部分可插入到连接器套筒中，并且其表面可滑动 接合，肩部和闩锁在表面上可滑动接合，并且闩锁定位成与肩部接合以锁定插入连接器套筒内的连接器主体。

公开(公告)号：US5662713A

公开(公告)日：1997-09-02

申请号：US528061

申请日：1995-09-14

Applicant: Erik Andersen ,  Ernst Peter Strecker

Inventor： Erik Andersen ,  Ernst Peter Strecker

IPC: A61F2/00 ,  A61F2/04 ,  A61F2/90 ,  A61F2/06

CPC classification number: A61F2/90 ,  A61F2/95 ,  A61F2/958 ,  D04B1/225 ,  A61F2/0077 ,  A61F2002/046 ,  A61F2210/0019 ,  A61F2210/0076 ,  A61F2230/0013 ,  A61F2230/0078 ,  A61F2250/0039 ,  D10B2509/06 ,  Y10S623/902

Abstract: A stent for reinforcement of the lumen of a peristaltic organ is formed by knitting preferably a nitinol wire into a pattern of overlapping loops selected such that from a relaxed state each row of loops may shift axially relative to and independently of the rows on either side. This local lengthening and shortening accommodate peristalsis of the organ without migrating within the organ. A stent is also shown which comprises two resilient cylindrical mesh layers and a semi-permeable compliant membrane such as expanded polytetrafluoroethylene, sandwiched between. The two mesh layers may be knit of a flexible filament, and the knit may be configured so that the stent can adapt to peristalsis of the body lumen. A method is also shown of manufacturing a delivery system for a resilient tubular device such as a stent so that the device can be inserted into the body in a substantially reduced diameter. The method uses a confining block having a bore and a slot leading into the bore. The tubular device is pinched and inserted into the bore and the slot, two mandrels are inserted into the bore, one inside the device and one outside and the mandrels are revolved about each other to roll the device on itself.

Abstract translation: 用于加强蠕动器官腔的支架通过优选地将镍钛诺丝编织成选择的重叠环的图案形成，使得从松弛状态，每排环可以相对于且独立于任一侧的行而轴向移动。 这种局部延长和缩短容纳器官的蠕动，而不会在器官内迁移。 还示出了一种支架，其包括两个弹性圆柱形网眼层和夹在其间的半透性柔顺膜，例如膨胀聚四氟乙烯。 两个网眼层可以是柔性细丝的编织物，并且针织物可以被配置成使得支架能够适应体腔的蠕动。 还示出了制造用于诸如支架的弹性管状装置的输送系统的方法，使得该装置可以以基本上减小的直径插入到体内。 该方法使用具有孔的限制块和通向孔的槽。 管状装置被夹持并插入孔和槽中，两个心轴插入孔中，一个在装置内部和一个外部，并且心轴彼此旋转以在其自身上滚动装置。