公开(公告)号：US20070191289A1

公开(公告)日：2007-08-16

申请号：US10591757

申请日：2005-03-03

申请人： Nobuhiko Fushimi ,  Hirotaka Teranishi ,  Kazuo Shimizu ,  Shigeru Yoneku ,  Fumiaki Ito ,  Masayuki Isaji

发明人： Nobuhiko Fushimi ,  Hirotaka Teranishi ,  Kazuo Shimizu ,  Shigeru Yoneku ,  Fumiaki Ito ,  Masayuki Isaji

IPC分类号： A61K31/7052 ,  C07H15/02

CPC分类号： A61K31/7056 ,  A61K31/706 ,  C07H17/02

摘要： The present invention provides nitrogen-containing fused-ring derivatives represented by the following general formula, or pharmaceutically acceptable salts thereof, or prodrugs thereof, which exhibit an excellent inhibitory activity in human SGLT and are useful as agents for the prevention or treatment of a disease associated with hyperglycemia such as diabetes, postprandial hyperglycemia, impaired glucose tolerance, diabetic complications or obesity, in the formula R1 represent H, an optionally substituted alkyl group, analkenyl group, etc.; R2 represent H, a halogen atom or an alkyl group; R3 and R4 represent H, OH, a halogen atom, an optionally substituted alkyl group, etc.; Y represents CH or N; Q represents alkylene, alkenylene, etc.; ring A represents an aryl group or a heteroaryl group; G represents a group represented by the following general formula (G-1) or (G-2) (in which E1 represents H, F or OH; and E2 represents H, F, a methyl group, etc.), and pharmaceutical compositions comprising the same, and pharmaceutical uses thereof.

摘要翻译： 本发明提供由以下通式表示的含氮稠环衍生物或其药学上可接受的盐或其前药，其在人SGLT中表现出优异的抑制活性，并且可用作预防或治疗疾病的药剂 与糖尿病，餐后高血糖症，葡萄糖耐量降低，糖尿病并发症或肥胖症等高血糖相关，其中R 1表示H，任选取代的烷基，断链基等; R 2表示H，卤素原子或烷基; R 3和R 4代表H，OH，卤素原子，任选取代的烷基等; Y表示CH或N; Q表示亚烷基，亚烯基等; 环A表示芳基或杂芳基; G表示由以下通式（G-1）或（G-2）表示的基团（其中E H表示H，F或OH;以及E < 表示H，F，甲基等），以及含有它们的药物组合物及其药物用途。

公开(公告)号：US07192130B2

公开(公告)日：2007-03-20

申请号：US10752511

申请日：2004-01-08

申请人： Kazuo Shimizu ,  Osamu Machida

发明人： Kazuo Shimizu ,  Osamu Machida

IPC分类号： B41J2/175 ,  B41J2/04

CPC分类号： B41J2/14145 ,  B41J2/17523 ,  B41J2/17563 ,  B41J2002/14403

摘要： An ink jet head includes: a pressure chamber that stores an ink and has an orifice; a filter plate including a through hole portion and a filter portion, the through hold portion disposed separately from the filter portion with a certain gap; a supply unit that supplies the ink through the filter portion to the pressure chamber; and a jetting unit that jets ink droplets through the orifice from the pressure chamber. The filter portion is formed to have a first aperture ratio. At least one through hole is formed on the through hole potion so that the filter portion has a second aperture ratio. The first aperture ratio is smaller than the second aperture ratio.

摘要翻译： 喷墨头包括：储存油墨并具有孔口的压力室; 所述过滤板包括通孔部分和过滤器部分，所述通过保持部分与所述过滤器部分分开设置有一定间隙; 供应单元，其通过过滤器部分将油墨供应到压力室; 以及喷射单元，其从压力室喷射墨滴通过孔口。 过滤器部分形成为具有第一孔径比。 在通孔部分上形成至少一个通孔，使得过滤器部分具有第二孔径比。 第一开口率小于第二开口率。

公开(公告)号：US06527375B2

公开(公告)日：2003-03-04

申请号：US10002106

申请日：2001-12-05

申请人： Shinya Kobayashi ,  Takahiro Yamada ,  Kunio Satou ,  Kazuo Shimizu ,  Hitoshi Kida

发明人： Shinya Kobayashi ,  Takahiro Yamada ,  Kunio Satou ,  Kazuo Shimizu ,  Hitoshi Kida

IPC分类号： B41J206

CPC分类号： B41J2/09

摘要： A single dot on a recording medium is formed by dots of a plurality of ink droplets ejected from different orifices 201 of a head 107. For example, four dots are formed overlapping one on the other to form a single dot. In order to suppress unevenness in ink density of a recording image due to undesirably shifted impact positions of these dots, impact positions of the dots for the single dots are shifted to the right and left on purpose by ¼-dot-worth of distance for each, that is, ½-dot-worth of distance in total. This printing method has a good effect on controlling noise element, which has a high special frequency and causes uneven ink density.

摘要翻译： 记录介质上的单个点由从头部107的不同孔201喷出的多个墨滴的点形成。例如，四个点形成为彼此重叠以形成单个点。 为了抑制由于这些点的不期望的偏移冲击位置引起的记录图像的墨水浓度的不均匀性，单个点的点的冲击位置向右和向左移动，每个点的距离为1/4点 ，即总共有1/2点的距离。 这种打印方法对控制噪声要素具有很好的效果，具有高特殊频率并导致油墨密度不均匀。

公开(公告)号：US06508537B2

公开(公告)日：2003-01-21

申请号：US09925603

申请日：2001-08-10

申请人： Takahiro Yamada ,  Shinya Kobayashi ,  Kunio Satou ,  Katsunori Kawasumi ,  Kazuo Shimizu ,  Hitoshi Kida

发明人： Takahiro Yamada ,  Shinya Kobayashi ,  Kunio Satou ,  Katsunori Kawasumi ,  Kazuo Shimizu ,  Hitoshi Kida

IPC分类号： B41J2155

CPC分类号： B41J2/155 ,  B41J2/085 ,  B41J2/09 ,  B41J2202/20

摘要： An ink jet recording device 10 includes a plurality of head modules 210 each formed with a plurality of nozzles for forming dots on a recording sheet 100. When the assembly of the head modules 210 has any positional error, recorded dots will shift to undesirable positions. However, the ink jet recording device 10 of the present invention adjust the dot forming positions to desirable positions in an electrical manner without actually and mechanically moving the head modules 210, both in directions perpendicular to and parallel with a nozzle line.

公开(公告)号：US06328397B1

公开(公告)日：2001-12-11

申请号：US09390669

申请日：1999-09-07

申请人： Kazuo Shimizu ,  Takuji Torii ,  Nobuhiro Noto ,  Yoshitaka Akiyama ,  Masatoshi Sakata ,  Shigenori Suematsu

发明人： Kazuo Shimizu ,  Takuji Torii ,  Nobuhiro Noto ,  Yoshitaka Akiyama ,  Masatoshi Sakata ,  Shigenori Suematsu

IPC分类号： B41J2938

CPC分类号： B41J2/04508 ,  B41J2/04573 ,  B41J2/04581 ,  B41J2/04588

摘要： To eliminate influence of cross-talk in an on-demand multi-nozzle ink jet head, drive pulses to be applied to piezoelectric elements for driving nozzles aligned in a row are individually adjusted so that the nozzles eject ink droplets at the same speed when the nozzles are driven simultaneously. To the piezoelectric elements which are deactuated during printing, a dummy drive pulse having a voltage level in a range from 50 to 75% of a minimum voltage for ejecting an ink droplet is applied, whereby the ejection speed achieved when individual nozzles are driven approaches the ejection speed achieved when all nozzles are driven simultaneously. As such, the print quality is improved.

摘要翻译： 为了消除按需多喷嘴喷墨头中的串扰的影响，单独调整要施加到用于驱动排列成行的喷嘴的压电元件的驱动脉冲，使得喷嘴以相同的速度喷射墨滴 喷嘴同时驱动。 对于在打印期间被去激活的压电元件，施加具有用于喷射墨滴的最小电压的50至75％范围内的电压电平的虚拟驱动脉冲，由此在驱动各个喷嘴时实现的喷射速度接近 所有喷嘴同时驱动时的喷射速度。 因此，打印质量得到改善。

公开(公告)号：US5681463A

公开(公告)日：1997-10-28

申请号：US608215

申请日：1996-02-28

申请人： Kazuo Shimizu ,  Satoru Matumoto ,  Makoto Nakagawa ,  Masashi Endo

发明人： Kazuo Shimizu ,  Satoru Matumoto ,  Makoto Nakagawa ,  Masashi Endo

IPC分类号： B01D61/14 ,  A61J1/14 ,  B01D61/18 ,  B01D63/02 ,  C02F1/00 ,  C02F1/28 ,  C02F1/44 ,  C02F9/00

CPC分类号： C02F1/003 ,  B01D61/18 ,  A61J1/145 ,  A61J1/1456 ,  A61J1/1468 ,  C02F2307/02

摘要： A portable liquid purifying device for dispensing a liquid, which includes a squeezable bottle made of a soft material and containing a mass of the liquid, a filtering member removably engaging a bottleneck of the bottle, and a cover assembly for covering a spout formed through the filtering member so as to fluid-tightly close the spout. The filtering member has a first section which accommodates activated carbon, and a second section which accommodates a micro-porous membrane filter including hollow fibers, the first and second sections being disposed in series so that the liquid delivered out of the bottle passes through the first and second sections in this order. The filtering member is fluid-tightly and air-tightly attached to the bottleneck such that the filtering member does not protrude past the bottleneck. The cover assembly has a first position for fluid-tightly closing the spout, and a second position for opening the spout so as to permit the liquid to flow out of the device.

摘要翻译： 一种用于分配液体的便携式液体净化装置，其包括由柔软材料制成并容纳液体的可挤压瓶子，可移除地接合瓶子瓶颈的过滤构件和用于覆盖通过所述瓶子形成的喷口的盖组件 过滤构件，以流体密封出口。 过滤构件具有容纳活性炭的第一部分和容纳包含中空纤维的微孔膜过滤器的第二部分，第一和第二部分串联设置，使得从瓶中排出的液体通过第一部分 和第二部分。 过滤构件流体密封并气密地附接到瓶颈，使得过滤构件不突出超过瓶颈。 盖组件具有用于流体密封出口的第一位置和用于打开喷口以允许液体流出设备的第二位置。

公开(公告)号：US5494146A

公开(公告)日：1996-02-27

申请号：US267355

申请日：1994-06-29

申请人： Hironobu Kurosawa ,  Toshitomo Kuwabara ,  Kazuo Shimizu

发明人： Hironobu Kurosawa ,  Toshitomo Kuwabara ,  Kazuo Shimizu

IPC分类号： G07D5/08 ,  G07D11/00

CPC分类号： G07D5/00

摘要： A coin selector for use in a coin mechanism of vending machines and the like is disclosed. The coin selector includes a device which determines whether a deposited coin is real or fake, and a movable gate which selectively conducts the deposited coin into a real coin chute or a fake coin chute in response to an operational result of the determining device. A detector is positioned upstream of the entrances to the real coin chute and the fake coin chute, and outputs an electrical signal which is dependent upon the position of the gate and the moving condition of the coin as it passes by the detector. The coin selector further includes a judging circuit which receives the output from the detector and determines whether the gate is in position to conduct the coin into the real coin chute or the fake coin chute. The judging circuit independently determines, based on the assumption that the gate is position to conduct the coin into the real coin chute, whether it can be concluded that the coin was in position to go into the real coin chute. If it is determined both that the gate was in position to conduct the coin into the real coin chute and that the coin was in position to be so conducted, the judging circuit outputs a signal indicating that the coin went into the real coin chute.

摘要翻译： 公开了一种用于自动售货机等的硬币机构的硬币选择器。 硬币选择器包括一个确定存放的硬币是真实的还是假的装置，以及可移动的门，其可以响应于确定装置的操作结果选择性地将存放的硬币导入真正的硬币滑槽或假的硬币槽。 探测器位于真实的硬币槽和假硬币槽的入口的上游，并输出取决于门的位置和硬币通过检测器的移动状态的电信号。 硬币选择器还包括判断电路，其接收来自检测器的输出，并且确定门是否位于将硬币导入真实的硬币滑槽或假硬币滑槽中。 判断电路基于假设门将硬币进入真实硬币槽的假设独立地确定，是否可以得出结论，硬币能够进入真正的硬币槽。 如果确定门处于将硬币进入真实硬币槽的位置，并且硬币处于如此导通的位置，则判断电路输出指示硬币进入真实硬币槽的信号。

公开(公告)号：US5386281A

公开(公告)日：1995-01-31

申请号：US64805

申请日：1993-05-21

申请人： Masao Mitani ,  Kazuo Shimizu

发明人： Masao Mitani ,  Kazuo Shimizu

IPC分类号： G03G15/20 ,  G03G21/00

CPC分类号： G03G15/2064

摘要： A thermal fixing device including a pair of rotating rollers which are press-contacted to each other, a heating section associated with at least one of the rollers and an image supporter having an unfixed toner image which is passed through a gap between the rollers so that the unfixed toner image is thermally (melt) fixed, the heating section having an integral structure type heating and cooling device which includes a cooler and a heater acting as a support, and wherein the fixing device further includes a thin endless metal belt which rotates while contacting the integral structure type device and which has a non-adhesive film on the outer surface of the belt, and a drive roller which drives the endless metal belt for rotation while applying tension to the endless metal belt. The surface temperature at a portion where the endless metal belt is in pressure-contact with the image supporter is first increased to a temperature (Tm) near the melting point of the toner and then cooled so that the image supporter can be stripped prior to the endless metal belt, and so that the temperature is higher than the glass transition point of the toner and lower than the softening point of the toner.

摘要翻译： 一种热定影装置，包括彼此压接的一对旋转辊，与至少一个辊相关联的加热部分和具有通过辊之间的间隙的未定影调色剂图像的图像载体，使得 未定影的调色剂图像被热（熔融）固定，加热部分具有包括冷却器和作为支撑件的加热器的整体结构型加热和冷却装置，并且其中定影装置还包括薄的环形金属带，其旋转同时 接触一体结构型装置，并且在带的外表面上具有非粘性膜;以及驱动辊，其驱动环形金属带旋转同时向环形金属带施加张力。 首先将环形金属带与图像载体压力接触的部分的表面温度升高到接近调色剂熔点的温度（Tm），然后冷却，使图像支持体在 并且使得温度高于调色剂的玻璃化转变点并低于调色剂的软化点。

公开(公告)号：USD353146S

公开(公告)日：1994-12-06

申请号：US7236

申请日：1993-04-16

申请人： Tadahiro Yaguchi ,  Hirohide Shimizu ,  Kazuo Shimizu

设计人： Tadahiro Yaguchi ,  Hirohide Shimizu ,  Kazuo Shimizu

公开(公告)号：US5089456A

公开(公告)日：1992-02-18

申请号：US606281

申请日：1990-10-31

申请人： Kazuyuki Maeda ,  Fujio Mizukami ,  Shuichi Niwa ,  Makoto Toba ,  Kazuo Shimizu

发明人： Kazuyuki Maeda ,  Fujio Mizukami ,  Shuichi Niwa ,  Makoto Toba ,  Kazuo Shimizu

IPC分类号： C01B33/26 ,  C04B35/195 ,  C04B35/624 ,  C07F7/02

CPC分类号： C01B33/26 ,  C04B35/195 ,  C04B35/624

摘要： A process for preparing a cordierite, which includes dissolving a silicon compound, an aluminum compound and a magnesium compound in a molar ratio of 1:0.7 to 1:0.3 to 0.5 in a complexing agent represented by the formula R(OCH.sub.2 CH.sub.2).sub.n OH, wherein R is an alkyl group and n is an integer of 1 to 4; heating the resulting solution to bring about a ligand exchange reaction of the silicon compound, aluminum compound and magnesium compound with the complexing agent; conducting hydrolysis to form a gel; drying the gel and sintering the dried gel at 800.degree. to 1450.degree. C.

摘要翻译： 一种制备堇青石的方法，其包括在由式R（OCH 2 CH 2）nOH表示的络合剂中将摩尔比为1:0.7至1:0.3至0.5的硅化合物，铝化合物和镁化合物溶解，其中 R为烷基，n为1〜4的整数。 加热所得溶液以引起硅化合物，铝化合物和镁化合物与络合剂的配体交换反应; 进行水解以形成凝胶; 干燥凝胶并将干燥的凝胶烧结在800°至1450℃。