公开(公告)号：US20070191904A1

公开(公告)日：2007-08-16

申请号：US11276107

申请日：2006-02-14

申请人： Imad Libbus ,  Jeffrey Stahmann

发明人： Imad Libbus ,  Jeffrey Stahmann

IPC分类号： A61N1/00

CPC分类号： A61N1/08 ,  A61B5/02055 ,  A61B5/0215 ,  A61B5/1116 ,  A61B5/4047 ,  A61B5/4519 ,  A61B5/686 ,  A61N1/05 ,  A61N1/056

摘要： This patent document discusses, among other things, apparatuses and methods including an expandable stimulation electrode with an integrated pressure sensor. In various examples, the apparatus further comprises a pulse generator, a controller, a posture sensor, or a physiological parameter sensor. When expanded, the electrode is adapted to abut a wall of a pulmonary artery, thereby providing an arterial anchor for the integrated pressure sensor. In addition, the expandable electrode provides a means to deliver baroreflex stimulation signals, generated by the pulse generator, to one or more baroreceptors in the arterial wall. Based on pressure sensor-provided signals indicative of an arterial blood pressure, the controller provides stimulation instructions to the pulse generator. The posture sensor may be used to normalize the pressure data or limit such data collection to a single posture orientation. In one example, the physiological parameter sensor includes a temperature sensor.

摘要翻译： 该专利文献尤其涉及包括具有集成压力传感器的可膨胀的刺激电极的装置和方法。 在各种示例中，该装置还包括脉冲发生器，控制器，姿态传感器或生理参数传感器。 当膨胀时，电极适于邻接肺动脉的壁，从而为集成压力传感器提供动脉锚。 此外，可扩张电极提供了将由脉冲发生器产生的压力反射刺激信号传递到动脉壁中的一个或多个压力感受器的装置。 基于压力传感器提供的指示动脉血压的信号，控制器向脉冲发生器提供刺激指令。 姿态传感器可用于对压力数据进行归一化或将这种数据收集限制到单个姿势取向。 在一个示例中，生理参数传感器包括温度传感器。

公开(公告)号：US20070106130A1

公开(公告)日：2007-05-10

申请号：US11619821

申请日：2007-01-04

申请人： John Hatlestsad ,  Qingsheng Zhu ,  Jeffrey Stahmann

发明人： John Hatlestsad ,  Qingsheng Zhu ,  Jeffrey Stahmann

IPC分类号： A61B5/00 ,  A61B5/08 ,  A61B5/05

CPC分类号： A61B5/0809 ,  A61B5/0816 ,  A61B5/1071 ,  A61B5/1116 ,  A61B5/1135 ,  A61B5/4806 ,  A61B5/6831 ,  A61B5/6846 ,  A61B5/686 ,  A61N1/36542

摘要： Systems and methods obtain information that allows detection of whether a patient suffers from congestion by monitoring a response of the patient to a recumbent position of the patient's body. The patient may be monitored to determine a respiration pattern for a non-recumbent position such as standing and a respiration pattern for a recumbent position such as lying down. The two patterns may be compared, either by a processing device or a physician, to determine a difference in the two respiration patterns. Furthermore, the congestion may be inferred from detecting an amount of time that the patient spends in a recumbent position or from detecting the recumbent angle that the patient obtains, either of which is presumed to indicate whether a recumbent position presents discomfort to the patient due to the presence of congestion.

摘要翻译： 系统和方法获得允许通过监视患者对患者身体的卧位的反应来检测患者是否患有拥塞的信息。 可以监测患者以确定用于躺卧位置的无卧位的呼吸模式，例如躺卧和躺卧位置的呼吸模式。 可以通过处理装置或医师来比较两种模式，以确定两种呼吸模式的差异。 此外，可以通过检测患者在躺卧位置中花费的时间量或从检测患者获得的躺卧角度来推断拥塞，其中任何一个被推定为指示躺卧位置是否由于患者的不适而给患者带来不适 拥堵的存在。

公开(公告)号：US20060271108A1

公开(公告)日：2006-11-30

申请号：US11135883

申请日：2005-05-24

申请人： Imad Libbus ,  Andrew Kramer ,  William Linder ,  Jeffrey Stahmann

发明人： Imad Libbus ,  Andrew Kramer ,  William Linder ,  Jeffrey Stahmann

IPC分类号： A61N1/36

CPC分类号： A61N1/36142 ,  A61N1/36114 ,  A61N1/36139 ,  A61N1/37

摘要： A neural stimulation system includes a safety control system that prevents delivery of neural stimulation pulses from causing potentially harmful effects. The neural stimulation pulses are delivered to one or more nerves to control the physiological functions regulated by the one or more nerves. Examples of such harmful effects include unintended effects in physiological functions associated with autonomic neural stimulation and nerve injuries caused by excessive delivery of the neural stimulation pulses.

公开(公告)号：US20060259086A1

公开(公告)日：2006-11-16

申请号：US11126490

申请日：2005-05-11

申请人： Yinghong Yu ,  Jiang Ding ,  Jeffrey Stahmann

发明人： Yinghong Yu ,  Jiang Ding ,  Jeffrey Stahmann

IPC分类号： A61N1/362

CPC分类号： A61N1/3682 ,  A61N1/3627 ,  A61N1/3706

摘要： Systems and methods to optimize atrioventricular delay during sensing or pacing of the atrium and for a plurality of sensed rates or pacing rates. In one example, a paced atrioventricular delay is calculated using a sensed atrioventricular interval and a paced atrioventricular interval. In another example, a plurality of paced atrioventricular delays for different pacing rates can be calculated. In another example embodiment, a plurality of sensed atrioventricular delays for different sensing rates can be calculated. Combinations of the various systems and methods are also possible.

摘要翻译： 在心房的感测或起搏期间以及多个感测速率或起搏速率下优化房室延迟的系统和方法。 在一个示例中，使用感测的房室间隔和起搏房室间隔来计算起搏房室延迟。 在另一个示例中，可以计算用于不同起搏速率的多个起搏房室延迟。 在另一示例性实施例中，可以计算用于不同感测速率的多个感测的房室延迟。 各种系统和方法的组合也是可能的。

公开(公告)号：US20060052830A1

公开(公告)日：2006-03-09

申请号：US11268284

申请日：2005-11-03

申请人： Julio Spinelli ,  Qingsheng Zhu ,  Jeffrey Stahmann ,  Andrew Kramer

发明人： Julio Spinelli ,  Qingsheng Zhu ,  Jeffrey Stahmann ,  Andrew Kramer

IPC分类号： A61N1/39

CPC分类号： A61N1/3622 ,  A61N1/3684

摘要： A system, method, or device classifies an arrhythmia according to the temporal order in which a depolarization wave associated with a particular heart contraction is received at a plurality of electrodes. One or more antiarrhythmia therapies is mapped to each arrhythmia classification. When a particularly classified arrhythmia is detected, the correspondingly mapped therapy list is selected and an appropriate antiarrhythmia therapy delivered. In one example, the particular therapy delivered in response to an arrhythmia depends at least in part on its historical success in treating arrhythmias of that classification.

公开(公告)号：US20060025827A1

公开(公告)日：2006-02-02

申请号：US11236192

申请日：2005-09-27

申请人： John Hatlesad ,  Quingsheng Zhu ,  Jeffrey Stahmann

发明人： John Hatlesad ,  Quingsheng Zhu ,  Jeffrey Stahmann

IPC分类号： A61N1/36 ,  A61B5/02 ,  A61B7/00

CPC分类号： A61B7/003 ,  A61N1/36514 ,  A61N1/36535

摘要： Adventitious lung sounds indicative of lung congestion are detected using an implantable sensor. The sensor is adapted to be positioned adjacent to a pulmonary system and to output signals indicative of lung sounds in response to pulmonary system activity. A controller receives the signals and processes the signals to detect the presence of adventitious lung sounds. A respiratory cycle sensor operating in conjunction with the lung-sound sensor enables classification of an adventitious lung sound according to its time occurrence within the respiratory cycle. Posture sensing in conjunction with lung-sound sensing provides valuable additional information as to the severity of the lung congestion.

公开(公告)号：US20060004418A1

公开(公告)日：2006-01-05

申请号：US11218865

申请日：2005-09-02

申请人： Jeffrey Stahmann ,  Andrew Kramer ,  James Gilkerson ,  Lorenzo DiCarlo ,  Rene Wentkowski

发明人： Jeffrey Stahmann ,  Andrew Kramer ,  James Gilkerson ,  Lorenzo DiCarlo ,  Rene Wentkowski

IPC分类号： A61N1/362

CPC分类号： A61N1/3627 ,  A61N1/3684

摘要： A method and system for managing refractory periods in a cardiac rhythm management device configured for biventricular or biatrial sensing. Refractory periods for each channel of the pacemaker are provided by interval timers that are triggered by sensed or paced events in order to prevent misinterpretation of sensing signals.

公开(公告)号：US20050228454A1

公开(公告)日：2005-10-13

申请号：US11142165

申请日：2005-06-01

申请人： Andrew Kramer ,  Jeffrey Stahmann ,  Veerichetty Kadhiresan

发明人： Andrew Kramer ,  Jeffrey Stahmann ,  Veerichetty Kadhiresan

IPC分类号： A61N1/362 ,  A61N1/365 ,  A61N1/368

CPC分类号： A61N1/3627 ,  A61N1/36521 ,  A61N1/36542 ,  A61N1/3682 ,  A61N1/3684

摘要： A method of optimizing cardiac resynchronization therapy delay over a patient's full range of activity for use in operating an implantable cardiac pacing device and such a device are disclosed. The method includes measuring selected conduction time between selected sites in the heart for a plurality of beats and logging the values on a periodic repeating programmable basis to produce cumulative data and constructing a current template of conduction time in relation to one or more other sensed parameters of interest over a desired range of patient activity levels. The current template is used to derive suggested optimum pacing timing.

公开(公告)号：US20050137629A1

公开(公告)日：2005-06-23

申请号：US10730760

申请日：2003-12-08

申请人： John Dyjach ,  Jeffrey Stahmann

发明人： John Dyjach ,  Jeffrey Stahmann

IPC分类号： A61B5/04 ,  A61N1/362 ,  A61N1/368 ,  A61N1/37

CPC分类号： A61N1/3627 ,  A61N1/3684 ,  A61N1/37

摘要： One aspect relates to a method to provide trended measurement of cardiac resynchronization therapy (CRT). In various embodiments of the method, data related to a status of a prescribed cardiac resynchronization therapy (CRT) in a cardiac rhythm management (CRM) device is recorded, and the data is processed into trended data useful for assessing the status of the prescribed CRT. The trended data is presented for use to assess the status of the prescribed CRT and assist with determining programming adjustments for improving the prescribed CRT. Other aspects are provided herein.

摘要翻译： 一个方面涉及提供心脏再同步治疗（CRT）的趋势测量的方法。 在该方法的各种实施例中，记录与心律管理（CRM）装置中的规定的心脏再同步治疗（CRT）的状态相关的数据，并且将该数据处理成用于评估规定的CRT的状态的趋势数据 。 趋势数据被提供用于评估规定的CRT的状态，并协助确定编程调整以改善规定的CRT。 本文提供了其他方面。

公开(公告)号：US20050137626A1

公开(公告)日：2005-06-23

申请号：US10742574

申请日：2003-12-19

申请人： Joseph Pastore ,  Jeffrey Stahmann

发明人： Joseph Pastore ,  Jeffrey Stahmann

IPC分类号： A61B5/113 ,  A61M31/00 ,  A61N1/362

CPC分类号： A61N1/3627 ,  A61B5/1135 ,  A61M31/002

摘要： A cardiac rhythm management system detects a condition indicative of acute decompensated heart failure and, in response, delivering a drug therapy. The system includes an implantable device communicating with a transdermal drug delivery device. The transdermal drug delivery device delivers a pharmaceutical substance in response to a detection of the condition by the implantable device. In one example, the implantable device detects the condition by monitoring a hemodynamic performance. In another example, the implantable device detects the condition by sensing a signal indicative of decompensation.

摘要翻译： 心律管理系统检测指示急性失代偿性心力衰竭的病症，并作为响应递送药物治疗。 该系统包括与透皮药物递送装置连通的可植入装置。 透皮药物递送装置响应于通过可植入装置检测到病症而递送药物物质。 在一个示例中，可植入装置通过监测血液动力学性能来检测状况。 在另一示例中，可植入装置通过感测指示失代偿的信号来检测该状况。