摘要:
An ice prevention network comprising a plurality of non-overlapping heater elements arranged in a grid along an airfoil is provided, powered by a multiphase power source, each phase powering selected heater elements that can selectively be powered on and powered off. The grid has a number of zones extending along the airfoil perpendicular to the airflow over the airfoil and a number of sections extending along the surface of the airfoil parallel to the airflow over the airfoil. Each of the heater elements is assigned to a single power phase and arranged such that an arbitrary section may be deactivated without causing a phase imbalance of more than one heating unit and such that a single zone may be activated without causing a phase imbalance of more than one heating unit.
摘要:
A climate control duct architecture having articulated and controlled interior surfaces to deliver variable and controllable airflow to target zones in the vehicle upon demand. By creating zone climates within the vehicle and providing conditioned airflow to only desired vehicle seating positions, the volume of necessary airflow is minimized, the need for cooling is reduced, and flexibility of the system is created. The interior surface may be mechanically or electrically controlled and may be situated in the common central “octopus” duct.
摘要:
Implantable compositions capable of providing release of bioactive agents according to a predetermined release profile and methods for their use. Such compositions include at least one ceramic substrate; a bioactive substance loaded on a surface of a said ceramic substrate forming a loaded surface zone operable to release said bioactive substance according to a release profile under physiological conditions; and a biodegradable polymer having an in vivo degradation period, forming a continuous or discontinuous coating on an area of a said ceramic substrate. The composition comprises at least two said loaded surface zones having different release profiles, or at least two said coatings having different in vivo degradation periods.
摘要:
A stabilized pharmaceutical composition of anticancer drug and a solvent like Polyethoxylated castor oil (cremophor) also containing any other suitable solubilizer suitable for human administration like dehydrated alcohol, is disclosed. Compositions prepared using this purified polyethoxylated castor oil enhance the stability of paclitaxel in such compositions.
摘要:
An effective prophylactic mucosal gene expression vaccine (GXV), made up of a cocktail of at least 4 different plasmid DNAs encoding corresponding RSV antigens, coacervated with chitosan to formulate nanospheres. In a murine model of RSV infection, intranasal administration with GXV results in significant induction of RSV-specific antibodies, nasal IgA antibodies, cytotoxic T lymphocytes, and IFN-γ production in the lung and splenocytes. A single dose of GXV induces a drastic reduction of viral titers.
摘要:
A method for forming an acetabular shell includes providing a working surface such as a mandrel, and spraying the working surface with a first layer of material having a first composition such as aluminum oxide. After a suitable thickness is generated, the spray composition is gradually changed to other compositions having desired particle sizes and distribution. In one example, the composition is changed to a mixture of aluminum oxide and titanium oxide and/or titanium. As thickness builds up, the relative amount of aluminum oxide is decreased such that the composition is all titanium and titanium oxide. After a desired thickness is generated, the acetabular shell is extracted off the mandrel.
摘要:
This invention relates to an orally effective herbal extract-based composition having broad-spectrum anticancer activity, more specifically a method of treating, inhibiting and/or preventing malignant tumors of the colon, intestine, stomach, breast, melanoma, glioblastoma, lung, cervix, ovary, prostate, oral cavity, larynx, liver, pancreas, kidney, bladder, endothelial cells, leukemia and myeloma using a herbal extract of Zizyphus, rich in betulinic acid. An advantage of the extract is that the betulinic acid has low systemic toxicity. The extract inhibits Protein Kinase C activity of cancer cells and induces apoptosis.
摘要:
A flush and fill process is used to ready a fuel cell cooling circuit for initial use. An external flushing system relasably connected to the cooling circuit circulates flushing coolant through the cooling circuit to remove contaminants from the wetted surfaces of the cooling circuit before the fuel cell is put into use. The flushing system includes a pump for circulating the flushing coolant through the cooling circuit, filters for removing contaminants from the coolant and a heater for elevating the temperature of the coolant. Following the flushing process to remove contaminants, the flushing system is disconnected from the cooling circuit and the cooling circuit is filled with fresh coolant.
摘要:
According to one general aspect, a method may include replicating, to a software-as-a-service application, a plurality of pieces of master data from a physically remote master database. The method may also include converting the plurality of pieces of master data into one or more pieces of local data of the software-as-a-service application. The method may include changing one or more of either the pieces of master data or the pieces of local data. The method may further include synchronizing the changed pieces of either master data or local data between the remote master database and the software-as-a-service application.