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    DUCT ARCHITECTURE FOR REGULATING CLIMATE ZONE IN A VEHICLE
    2.
    发明申请
    DUCT ARCHITECTURE FOR REGULATING CLIMATE ZONE IN A VEHICLE 审中-公开
    用于调节车辆中的气候区的导管结构

    公开(公告)号：US20100216387A1

    公开(公告)日：2010-08-26

    申请号：US12389400

    申请日：2009-02-20

    申请人： Mukesh Kumar ,  Paul Bryan Hoke

    发明人： Mukesh Kumar ,  Paul Bryan Hoke

    IPC分类号： B60H1/34 ,  F24F13/10

    CPC分类号： B60H1/26 ,  B60H1/00564 ,  F24F13/10

    摘要： A climate control duct architecture having articulated and controlled interior surfaces to deliver variable and controllable airflow to target zones in the vehicle upon demand. By creating zone climates within the vehicle and providing conditioned airflow to only desired vehicle seating positions, the volume of necessary airflow is minimized, the need for cooling is reduced, and flexibility of the system is created. The interior surface may be mechanically or electrically controlled and may be situated in the common central “octopus” duct.

    摘要翻译： 一种气候控制管道结构，具有铰接和受控的内表面，以根据需要将可变且可控的气流输送到车辆中的目标区域。 通过在车辆内部产生区域气候并将调节气流提供给仅仅期望的车辆座位位置，所需的气流量被最小化，减少了冷却的需要，并且产生了系统的灵活性。 内表面可以是机械或电气控制的并且可以位于公共中央“章鱼”管道中。

    Airflow control in floor mode for vehicle with multiple seating rows
    3.
    发明授权
    Airflow control in floor mode for vehicle with multiple seating rows 有权
    具有多个座位排的车辆的地面模式下的气流控制

    公开(公告)号：US09102215B2

    公开(公告)日：2015-08-11

    申请号：US13274729

    申请日：2011-10-17

    申请人： Mukesh Kumar ,  Paul B. Hoke ,  Martha E. Nefcy ,  David Wong

    发明人： Mukesh Kumar ,  Paul B. Hoke ,  Martha E. Nefcy ,  David Wong

    IPC分类号： B60H1/00 ,  F28F27/00 ,  F24F11/00

    CPC分类号： B60H1/00842 ,  B60H1/00021 ,  B60H1/00735 ,  B60H1/00742 ,  B60H2001/002 ,  F24F11/30 ,  F24F2110/00 ,  F24F2110/10 ,  F24F2120/10

    摘要： A comfort system is provided for a motor vehicle. A seat occupancy sensor determines whether a third row zone is occupied. At least one flow controller is provided in the floor duct for controllably supplying the conditioned airflow to at least the third row outlet. If the third row zone is occupied, then a second row outlet and the third row outlet are turned on to supply a conditioned airflow to a front seat zone, a second row zone, and the third row zone. If the third row zone is not occupied, then the third row outlet is closed off. If the second row zone is not occupied, then the second and third row outlets are closed off. If occupied, then the second row outlet is turned on until a desired comfort level is achieved in the second row zone.

    摘要翻译： 为汽车提供舒适系统。 座椅占用传感器确定第三行区域是否被占用。 至少一个流量控制器设置在地板管道中，用于可控地将经调节的气流提供给至少第三排出口。 如果第三排区域被占用，则第二排出口和第三排出口被打开以向前排座位区域，第二排区域和第三行区域提供经调节的气流。 如果第三排区域未被占用，则第三行出口被关闭。 如果第二行区域未被占用，则第二和第三行出口被关闭。 如果被占用，则第二排出口被打开，直到在第二行区域中达到期望的舒适度。

    Air ducts formed in automotive structural members
    4.
    发明授权
    Air ducts formed in automotive structural members 有权
    在汽车结构件中形成的空气管道

    公开(公告)号：US08641134B2

    公开(公告)日：2014-02-04

    申请号：US13437423

    申请日：2012-04-02

    申请人： Robert S. Sawyer ,  Mukesh Kumar ,  Martha E. Nefcy

    发明人： Robert S. Sawyer ,  Mukesh Kumar ,  Martha E. Nefcy

    IPC分类号： B60H1/24

    CPC分类号： B60H1/00564 ,  B60H1/245 ,  B60H1/246

    摘要： An air duct for an automotive vehicle is blow molded with an elongated, hollow structural member to be used as a portion of a body of the vehicle. The structural member has an inner wall defining an elongated cavity communicating with first and second access holes at respective longitudinal positions along the structural member. A parison comprised of a thermally insulating material is inserted into the internal cavity. A source of inflation gas is connected to a mouth portion or the parison. The parison is heated and inflated within the internal cavity to an expanded shape to form the air duct disposed against the inner wall and spanning the first and second access holes. The air duct at one of the access holes is configured as an air inlet. The air duct at the other one of the access holes is configured as an air outlet.

    摘要翻译： 用于机动车辆的空气管道是吹塑成型的，具有细长的中空结构件，用作车身的一部分。 结构构件具有限定在沿着结构构件的各个纵向位置处与第一和第二进入孔连通的细长腔的内壁。 将由隔热材料构成的型坯插入内部空腔。 膨胀气体源连接到口部或型坯。 型坯在内腔内被加热膨胀成扩张形状，以形成靠在内壁上并横跨第一和第二进入孔的空气通道。 一个进入孔的空气管道被构造为空气入口。 在另一个进入孔的空气管道被配置为空气出口。

    Air Ducts Formed in Automotive Structural Members
    5.
    发明申请
    Air Ducts Formed in Automotive Structural Members 有权
    空气管道组成汽车结构件

    公开(公告)号：US20130257106A1

    公开(公告)日：2013-10-03

    申请号：US13437423

    申请日：2012-04-02

    申请人： Robert S. Sawyer ,  Mukesh Kumar ,  Martha E. Nefcy

    发明人： Robert S. Sawyer ,  Mukesh Kumar ,  Martha E. Nefcy

    IPC分类号： B60H1/26 ,  B29C49/22

    CPC分类号： B60H1/00564 ,  B60H1/245 ,  B60H1/246

    摘要： An air duct for an automotive vehicle is blow molded with an elongated, hollow structural member to be used as a portion of a body of the vehicle. The structural member has an inner wall defining an elongated cavity communicating with first and second access holes at respective longitudinal positions along the structural member. A parison comprised of a thermally insulating material is inserted into the internal cavity. A source of inflation gas is connected to a mouth portion or the parison. The parison is heated and inflated within the internal cavity to an expanded shape to form the air duct disposed against the inner wall and spanning the first and second access holes. The air duct at one of the access holes is configured as an air inlet. The air duct at the other one of the access holes is configured as an air outlet.

    摘要翻译： 用于机动车辆的空气管道是吹塑成型的，具有细长的中空结构件，用作车身的一部分。 结构构件具有限定在沿着结构构件的各个纵向位置处与第一和第二进入孔连通的细长腔的内壁。 将由隔热材料构成的型坯插入内部空腔。 膨胀气体源连接到口部或型坯。 型坯在内腔内被加热膨胀成扩张形状，以形成靠在内壁上并横跨第一和第二进入孔的空气通道。 一个进入孔的空气管道被构造为空气入口。 在另一个进入孔的空气管道被配置为空气出口。

    Modular Junction Seal Of An Orthopedic Implant
    6.
    发明申请
    Modular Junction Seal Of An Orthopedic Implant 有权
    矫形植入物的模块接头密封

    公开(公告)号：US20130204389A1

    公开(公告)日：2013-08-08

    申请号：US13366510

    申请日：2012-02-06

    申请人： Mukesh Kumar ,  Robert M. Ronk ,  Daniel E. Williamson

    发明人： Mukesh Kumar ,  Robert M. Ronk ,  Daniel E. Williamson

    IPC分类号： A61F2/32

    CPC分类号： A61F2/3609 ,  A61F2002/30332 ,  A61F2002/30589 ,  A61F2002/30682 ,  A61F2002/365

    摘要： A seal for preventing a bodily fluid from penetrating an orthopedic implant comprising a tapered section adapted to conformingly mate to a stem of a first implant component, and a collar section extending from and circumferentially surrounding a portion of the tapered section, the collar section adapted to mate to a base of a second implant component such that the tapered section and collar section define an opening therethrough configured to receive the first implant component.

    摘要翻译： 一种用于防止体液穿透整形外科植入物的密封件，包括适于与第一植入部件的杆顺从地配合的锥形部分，以及从锥形部分的一部分延伸并周向围绕锥形部分的颈环部分， 配合到第二植入部件的基部，使得锥形部分和凸缘部分限定通过其构造成接收第一植入部件的开口。

    DRUG DELIVERY AND DIAGNOSTIC SYSTEM FOR ORTHOPEDIC IMPLANTS
    7.
    发明申请
    DRUG DELIVERY AND DIAGNOSTIC SYSTEM FOR ORTHOPEDIC IMPLANTS 有权
    用于正交植入物的药物递送和诊断系统

    公开(公告)号：US20110218644A1

    公开(公告)日：2011-09-08

    申请号：US13039362

    申请日：2011-03-03

    申请人： Jason Meridew ,  Mukesh Kumar ,  Tayler E. Kreider

    发明人： Jason Meridew ,  Mukesh Kumar ,  Tayler E. Kreider

    IPC分类号： A61M25/04 ,  A61F2/36

    CPC分类号： A61M5/14 ,  A61F2/34 ,  A61F2/3662 ,  A61F2/389 ,  A61F2002/3068 ,  A61F2002/368 ,  A61F2002/3694 ,  A61M5/14276 ,  A61M39/0208 ,  A61M2205/3523 ,  A61M2210/086

    摘要： A drug delivery and diagnostic system can include an orthopedic implant having an outer attachment surface. A conduit can be coupled to the outer attachment surface. The conduit can have an inlet and a plurality of perforations formed along a length thereof. The conduit can be adapted to pass fluid between the inlet and the perforations. A subcutaneous port can be fluidly coupled to the inlet and be adapted to communicate fluid through the inlet, along the conduit and out of the perforations around and along the outer attachment surface of the orthopedic implant.

    摘要翻译： 药物递送和诊断系统可以包括具有外部附接表面的矫形植入物。 管道可以联接到外部附接表面。 导管可以具有沿其长度形成的入口和多个穿孔。 导管可适于在入口和穿孔之间传递流体。 皮下端口可以流体地联接到入口，并且适于沿着导管和通过整形外科植入物的外部附接表面的穿孔穿过入口传送流体。

    COMPOSITIONS COMPRISING ANTI-ICAM-1 ANTIBODIES
    8.
    发明申请
    COMPOSITIONS COMPRISING ANTI-ICAM-1 ANTIBODIES 审中-公开
    包含抗ICAM-1抗体的组合物

    公开(公告)号：US20110052601A1

    公开(公告)日：2011-03-03

    申请号：US12390246

    申请日：2009-02-20

    申请人： Shyam S. Mohapatra ,  Aruna Behera ,  Hiroto Matsuse ,  Mukesh Kumar

    发明人： Shyam S. Mohapatra ,  Aruna Behera ,  Hiroto Matsuse ,  Mukesh Kumar

    IPC分类号： A61K39/42 ,  A61P11/00 ,  A61P31/12

    CPC分类号： C12N15/1138 ,  C12N15/111 ,  C12N2310/11 ,  C12N2320/32

    摘要： There is provided a method of preventing a respiratory infection by administering an effective amount of an agent for regulating ICAM-1 expression. Also provided is a composition for the prevention of respiratory infection including an agent which regulates ICAM expression. method of preventing RSV infection by administering an effective amount of an agent that interferes with the binding of RSV to ICAM-1. A method of preventing RSV infection by administering an effective amount of an agent that down regulates the expression of ICAM-1, thereby decreasing RSV binding to ICAM-1 is also provided. There is provided a method of treating RSV infection by administering an effective amount of an agent for down regulating ICAM-1 expression. A method of blocking RSV-ICAM-1 interaction by administering an effective amount of agents for blocking ICAM sites of binding is provided. Also provided is a compound for blocking RSV-ICAM-1 interaction including an agent for blocking ICAM sites of binding.

    摘要翻译： 提供了一种通过施用有效量的用于调节ICAM-1表达的试剂来预防呼吸道感染的方法。 还提供了用于预防呼吸道感染的组合物，包括调节ICAM表达的药剂。 通过施用有效量的妨碍RSV与ICAM-1的结合的试剂来预防RSV感染的方法。 还提供了通过施用有效量的下调ICAM-1的表达的试剂，从而降低RSV与ICAM-1的结合来预防RSV感染的方法。 提供了通过施用有效量的用于下调ICAM-1表达的试剂来治疗RSV感染的方法。 提供了通过施用有效量的阻断ICAM结合位点的试剂阻断RSV-ICAM-1相互作用的方法。 还提供了用于阻断RSV-ICAM-1相互作用的化合物，其包括用于阻断结合的ICAM位点的试剂。

    Tibial Tray Having a Reinforcing Member
    9.
    发明申请
    Tibial Tray Having a Reinforcing Member 审中-公开
    胫骨托具有加强构件

    公开(公告)号：US20100100191A1

    公开(公告)日：2010-04-22

    申请号：US12579479

    申请日：2009-10-15

    申请人： Brian M. May ,  Mukesh Kumar

    发明人： Brian M. May ,  Mukesh Kumar

    IPC分类号： A61F2/38 ,  A61B17/56

    CPC分类号： A61F2/389 ,  A61F2/30767 ,  A61F2/30965 ,  A61F2002/30769 ,  A61F2002/30879 ,  A61F2002/30881 ,  A61F2002/30883 ,  A61F2002/30884 ,  A61F2002/3092 ,  A61F2240/001 ,  A61F2310/00023 ,  A61F2310/00179

    摘要： A knee joint prosthesis can include a tibial component that can have a tibial tray. The tibial tray can include a platform-like tray that defines a superior surface and an inferior surface. The platform-like tray can have a tray perimeter and a raised wall formed on the inferior surface. The raised wall can be offset inboard relative to the tray perimeter. Porous material can be disposed on the inferior surface of the platform-like tray at a location generally between the raised wall and the tray perimeter.

    摘要翻译： 膝关节假体可以包括可具有胫骨托的胫骨部件。 胫骨托可包括限定上表面和下表面的平台状托盘。 平台状托盘可以具有托盘周边和形成在下表面上的凸起壁。 凸起的壁可以相对于托盘周边在内侧偏移。 多孔材料可以在通常在凸起壁和托盘周边之间的位置处设置在平台状托盘的下表面上。