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71.发明授权Introducer sheath having a hemostasis valve with an adhesive means for attachment to the skin 有权引导器护套具有止血阀，其具有用于附接到皮肤的粘合装置公开(公告)号：US08262625B1
公开(公告)日：2012-09-11
申请号：US13105043
申请日：2011-05-11
CPC分类号： A61M25/0662 , A61M25/0097 , A61M25/02 , A61M2025/0266 , A61M2025/028
摘要： An introducer sheath for placement of a tubular shaft into the vascular system of a human subject. The introducer sheath has a tubular shaft, a side arm, and a hemostasis valve placed at a proximal portion of the introducer sheath. The hemostasis valve has an adhesive pad formed integral with the shell of the hemostasis valve. The adhesive pad is designed to attach and detach a proximal section of the introducer sheath to and from the skin of the human subject.
摘要翻译： 用于将管状轴放置到人类受试者的血管系统中的导引鞘。 引导器鞘具有管状轴，侧臂和放置在导引鞘的近端部分处的止血阀。 止血阀具有与止血阀壳体一体形成的粘合垫。 粘合垫被设计成将引导器护套的近端部分附着和分离到人类受试者的皮肤上和从皮肤上分离。
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公开(公告)号：US5011490A
公开(公告)日：1991-04-30
申请号：US447187
申请日：1989-12-07
CPC分类号： A61B17/32075
摘要： An Endoluminal Tissue Excision Catheter (ETEC) is described which is capable of excising obstructive tissue from a vessel in a living body. The ETEC system operates by first passing a guide wire through the vessel and beyond the obstructive tissue. The ETEC catheter is then advanced over the guide wire until its distal end lies beyond the obstructive tissue. A closing catheter portion of ETEC is then pulled back from a cut/collect catheter portion of the ETEC thus exposing a cutting edge located at the proximal end of a cylindrical cutting blade located at a distal portion of the cut/collect catheter. A rotating means is then attached to the cut/collect catheters'3 s proximal end. The cut/collect catheter is then pulled back in a retrograde direction while rotating, thus cutting and collecting the excised obstructive tissue into a tissue collection chamber that is formed within the cylindrical cutting blade. The entire ETEC system including the cut/collect and closing catheters and the guide wire is then removed from the vessel. Means are provided to flush the collected tissue out of the tissue collection chamber after the ETEC catheter is outside of the living body.
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73.发明授权Guide wire following tunneling catheter system and method for transluminal arterial atherectomy 失效导丝跟随隧道导管系统和腔内动脉粥样斑块切除术的方法
公开(公告)号：US4898575A
公开(公告)日：1990-02-06
申请号：US205541
申请日：1988-06-10
CPC分类号： A61B17/3207 , A61B17/22012 , A61B18/14 , A61B2017/22038 , A61B2217/005
摘要： An atherectomy catheter is advanced over a guide wire in the anterograde direction to the site of an arterial stenosis. The distal end of the catheter is centered around the guide wire which has been previously advanced through the stenotic lumen. The catheter is then advanced over the guide wire with its sharpened distal end cutting through the stenosis. The atherectomy catheter can also employ rotation or vibration or an electrocautery current to enhance the catheter's cutting action. Suction applied at the catheter's proximal end is used to enhance the collection of plaque cut from the stenosis at the catheter's distal end so that the cut plaque enters a single passageway that lies between the outer surface of the guide wire and the inner surface of the cylindrical catheter.
摘要翻译： 动脉粥样硬化切除术导管沿横行方向前进到导管位于动脉狭窄部位。 导管的远端围绕先前通过狭窄管腔前进的引导线居中。 然后将导管推过导丝，其尖锐的远端切穿狭窄。 粥样斑块切除术导管还可以采用旋转或振动或电灼电流来增强导管的切割动作。 在导管的近端施加的吸力用于增强从导管远端的狭窄切割的斑块的收集，使得切割的斑块进入位于导丝的外表面和圆柱形内表面之间的单个通道 导管。
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公开(公告)号：US08535294B2
公开(公告)日：2013-09-17
申请号：US13150308
申请日：2011-06-01
IPC分类号： A61M25/00
CPC分类号： A61M25/0054 , A61M25/0045 , A61M25/005
摘要： The present invention is a carotid sheath that has a proximal portion that is stiffer than the distal portion of the sheath as a result of the proximal portion having a higher durometer of the outer plastic coating of the sheath's proximal portion with a lower durometer for the plastic coating on the more flexible distal portion of the sheath. Another means to increase the flexibility of the sheath's distal portion compared to a stiffer proximal portion is by having a slightly smaller outside diameter for the outer plastic coating of the distal portion of the sheath. A more flexible distal portion of the sheath allows easier access for angiography, angioplasty or stenting when the sheath is used to access the tortuous path encountered when entering the carotid arteries.
摘要翻译： 本发明是一种颈动脉鞘，其具有比鞘的远端部更硬的近端部分，因为近端部分具有较高硬度的护套近端部分的塑料涂层，其中较低的硬度计用于塑料 涂覆在护套的更柔性的远端部分上。 与较硬的近端部分相比，增加护套远端部分的灵活性的另一种手段是通过对鞘的远侧部分的外部塑料涂层具有略小的外径。 当护套用于进入进入颈动脉期间遇到的曲折路径时，鞘的更柔性的远侧部分允许更容易地进行血管造影，血管成形术或支架置入。
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公开(公告)号：US5167644A
公开(公告)日：1992-12-01
申请号：US656591
申请日：1991-02-19
摘要： A sheath for percutaneous insertion into an artery includes a manually insertable sealing tab having a flexible hinge molded onto the sheath near its proximal end. The tab includes a cylindrically shaped stopper that can be inserted into the sheath's proximal end to prevent blood loss when there is no catheter inserted into the sheath. The stopper design allows a guide wire to remain in place or be advanced or pulled out of the sheath when the stopper is in place to seal the sheath's proximal end.
摘要翻译： 用于经皮插入动脉的鞘包括可手动插入的密封片，其具有在其近端附近模制到护套上的柔性铰链。 翼片包括一个圆柱形的止动器，可以插入护套的近端，以防止当没有导管插入护套时失血。 止动器设计允许导线保持在适当位置，或者当止动器就位以密封护套的近端时，引导线保持在适当位置或被推进或拉出护套。
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76.发明授权
公开(公告)号：US5059166A
公开(公告)日：1991-10-22
申请号：US448691
申请日：1989-12-11
IPC分类号： A61B17/00 , A61F2/00 , A61F2/82 , A61F2/88 , A61K51/12 , A61L31/14 , A61M36/00 , A61M36/04 , A61N5/10
CPC分类号： A61F2/82 , A61F2/0077 , A61F2/88 , A61K51/1282 , A61L31/14 , A61N5/1002 , A61F2210/0095
摘要： Intra-arterial stents are frequently used subsequent to balloon angioplasty to maintain arterial patency. The most frequent cause for failure to maintain patency is the rapid growth of the injured arterial tissue through the openings in the stent, which rapid growth is called "intimal hyperplasia." Since irradiation from a radioisotope source is capable of selectively inhibiting the growth of hyperproliferating cells as compared with normal cells, a radioisotope material which forms part of the stent can be used to decrease the rate of arterial reclosure. The radioisotope could be placed inside the stent, alloyed into the metal from which the stent is made, or preferably, it can be coated onto the stent's exterior surface. Beta emitting radioisotopes having a half-life between 1 and 100 days would be best suited as a stent coating because of their comparatively short range of action within human tissue, and because of their comparatively short half-life. An anti-thrombogenic coating placed on the outer surface of the radioisotope stent would further reduce arterial reclosure by decreasing stent thrombogenicity.
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公开(公告)号：US20130184735A1
公开(公告)日：2013-07-18
申请号：US13349060
申请日：2012-01-12
IPC分类号： A61M29/00
CPC分类号： A61M29/00 , A61M25/0662 , A61M2025/0183 , A61M2025/0188 , A61M2025/0681
摘要： Dilators and sheaths for use in minimally invasive vascular therapy are disclosed. In some embodiments, the dilators include a slot that accesses a guidewire lumen within the dilator. These slots facilitate rapid exchange of one dilator for another. In another embodiment, a dilator is sufficiently stiff to facilitate entry, but also designed to facilitate placement of the dilator along a tortuous path.
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公开(公告)号：US5484425A
公开(公告)日：1996-01-16
申请号：US321806
申请日：1994-10-12
IPC分类号： A61M25/00 , A61M25/06 , A61M25/098
CPC分类号： A61M25/0662 , A61M25/005 , A61M25/0054 , A61M2025/0081 , A61M25/0053
摘要： This invention provides a non-kinking and thin-walled introducer sheath (10) having a flat wire metal coil (12) that lies within a plastic covering (20) fitted onto the exterior surface of the flat wire metal coil (12) and extends into a space between adjacent turns of the flat wire metal coil (12) without covering the interior surface. Each turn of the flat wire metal coil (12) has a thickness within the range between 0.75-3.0 mils with a width to thickness ratio lying between 12 and 80. A plastic adapter (30) is provided and is located at a proximal end of the sheath (10) for inserting guide wires through the sheath (10) into a vessel.
摘要翻译： 本发明提供一种具有扁平线金属线圈（12）的非扭结和薄壁引导器护套（10），该扁平线金属线圈（12）位于安装在扁平线金属线圈（12）的外表面上的塑料覆盖物（20）内并延伸 进入扁平线金属线圈（12）的相邻匝之间的空间，而不覆盖内表面。 扁平线金属线圈（12）的每一圈的厚度在0.75-3.0密耳之间的范围内，宽度与厚度之比位于12和80之间。提供塑料适配器（30）并且位于 所述护套（10）用于将引导线穿过所述护套（10）插入容器中。
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79.发明授权Use of a stent with the capability to inhibit malignant growth in a vessel such as a biliary duct 失效使用具有抑制诸如胆管的血管中恶性生长能力的支架
公开(公告)号：US5176617A
公开(公告)日：1993-01-05
申请号：US779641
申请日：1991-10-21
IPC分类号： A61B19/00 , A61F2/00 , A61F2/82 , A61F2/88 , A61K51/12 , A61L31/14 , A61L31/16 , A61M36/12 , A61N5/10
CPC分类号： A61F2/88 , A61F2/0077 , A61F2/82 , A61K51/1282 , A61L31/14 , A61L31/16 , A61N5/1002 , A61F2210/0095 , A61L2300/416 , A61L2300/44 , A61N2005/1089
摘要： It is well known that radiation therapy can reduce the proliferation of rapidly growing cancer cells is a malignant tumor. The present invention utilizes a radioisotope which is integral to a stent which can irradiate the tissue in close proximity to the implantation site of the stent in order to reduce the rapid growth of malignant cells in a vessel, such as a bile duct while simultaneously maintaining vessel patency. The radioisotope could be place inside the stent, alloyed into the metal from which the stent is made, or preferably, it can be coated onto the stent's exterior surface.
摘要翻译： 众所周知，放射治疗可以减少快速生长的癌细胞的增殖是恶性肿瘤。 本发明利用放射性同位素，该放射性同位素可以在靠近支架植入部位照射组织的支架上成一体，以便减少容器如胆管中的恶性细胞的快速生长，同时保持血管 通畅 放射性同位素可以放置在支架内，合金化成制造支架的金属，或者优选地，其可以涂覆在支架的外表面上。
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公开(公告)号：US4765332A
公开(公告)日：1988-08-23
申请号：US885139
申请日：1986-07-14
CPC分类号： A61B17/32075 , A61B2017/22038
摘要： An atherectomy apparatus and method is disclosed for the purpose of surgical excision of atheromas which typically consist of plaque deposits that cause narrowing (stenosis) of an artery. The apparatus, called a pullback atherectomy catheter, cuts and collects obstructive material into a collection chamber as the catheter is pulled back through obstructive material within a human vessel such as an artery.
摘要翻译： 公开了用于手术切除动脉粥样化的目的的粥样斑块切除装置和方法，其通常由导致动脉狭窄（狭窄）的斑块沉积物组成。 被称为回拉式动脉粥样硬化斑块切除术导管的装置在导管通过诸如动脉之类的人容器内的阻塞物质被拉回时将切割并收集阻塞物质到收集室中。
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