公开(公告)号：US09459331B2

公开(公告)日：2016-10-04

申请号：US13984855

申请日：2012-02-01

申请人： Yosuke Otake ,  Yoshihisa Soutome ,  Ryota Sato ,  Yoshitaka Bito ,  Koji Hirata

发明人： Yosuke Otake ,  Yoshihisa Soutome ,  Ryota Sato ,  Yoshitaka Bito ,  Koji Hirata

IPC分类号： G01R33/3415 ,  G01R33/36 ,  G01R33/422 ,  G01R33/34

CPC分类号： G01R33/365 ,  G01R33/34053 ,  G01R33/34069 ,  G01R33/34076 ,  G01R33/3415 ,  G01R33/3635 ,  G01R33/3657 ,  G01R33/3678 ,  G01R33/422

摘要： To provide a technique for sufficiently eliminating magnetic coupling between RF coils and improving image quality when a multi-element multi-tuned RF coil is used as a receive RF coil for an MRI device. In the invention, each of RF coils which constitute a multi-element multi-tuned RF coil which is used as a receive RF coil for an MRI device is provided with an inter-coil magnetic coupling prevention circuit which resonates at each frequency to which each RF coil is tuned and provides a high impedance. The inter-coil magnetic coupling prevention circuit adjusts an inductor and a capacitor so that both of a circuit on the side of a pre-amplifier viewed from both ends of a signal reception circuit and a circuit on the side of the signal reception circuit viewed from both ends of a serial resonance circuit connected to the pre-amplifier resonate at a plurality of frequencies to which the respective RF coils are tuned.

摘要翻译： 提供一种用于充分消除RF线圈之间的磁耦合并且当多元素多调谐RF线圈用作MRI装置的接收RF线圈时提高图像质量的技术。 在本发明中，构成用作MRI装置的接收RF线圈的多元素多调谐RF线圈的每个RF线圈都设置有线圈间磁耦合防止电路，该电路在每个频率下共振， RF线圈被调谐并提供高阻抗。 线圈间磁耦合防止电路调整电感器和电容器，使得从信号接收电路的两端观看的前置放大器侧的电路和从信号接收电路侧观察的电路 连接到前置放大器的串联谐振电路的两端以相应的RF线圈调谐到的多个频率谐振。

公开(公告)号：US09091744B2

公开(公告)日：2015-07-28

申请号：US13697122

申请日：2011-05-02

申请人： Satoshi Hirata ,  Yoshitaka Bito

发明人： Satoshi Hirata ,  Yoshitaka Bito

IPC分类号： G01V3/00 ,  G01R33/485 ,  G01R33/483 ,  G01R33/56 ,  G01R33/561

CPC分类号： G01R33/485 ,  G01R33/4833 ,  G01R33/5607 ,  G01R33/5617

摘要： An object of the present invention is to provide a measuring technique which allows in the MRS measurement to suppress with a high degree of precision, incorporation of a signal of unwanted compounds which hinders measurement of a measurement object signal, independent of an imaging object region and the measurement object signal, thereby obtaining a stable and favorable signal spectrum. In the MRS measuring sequence, a spectrum selective inversion RF pulse, having a narrow band characteristic for selectively inverting only a signal peak of a compounds to be suppressed, and phase dispersion-refocusing GC pulses are applied at least one of before and after a region selective RF pulse. This MRS measuring sequence is repeated while changing the echo time TE at predetermined intervals, and nuclear magnetic resonance signals being obtained by the repetition are integrated. The amount of the spectrum selective inversion RF pulse to be applied may be changed according to the echo time TE.

摘要翻译： 本发明的目的是提供一种测量技术，其允许在MRS测量中以高精确度抑制，不依赖于成像对象区域而引入妨碍测量对象信号的测量的不想要的化合物的信号，以及 测量对象信号，从而获得稳定和有利的信号频谱。 在MRS测量序列中，具有用于选择性地仅反转待抑制的化合物的信号峰的窄带特性和相位色散重新聚焦GC脉冲的频谱选择性反转RF脉冲施加在区域之前和之后的至少一个 选择性RF脉冲。 在以预定间隔改变回波时间TE的同时重复该MRS测量序列，并且通过重复获得的核磁共振信号被积分。 可以根据回波时间TE改变要施加的频谱选择性反转RF脉冲的量。

公开(公告)号：US08547101B2

公开(公告)日：2013-10-01

申请号：US13123299

申请日：2009-07-22

申请人： Satoshi Hirata ,  Yoshitaka Bito

发明人： Satoshi Hirata ,  Yoshitaka Bito

IPC分类号： G01V3/00

CPC分类号： G01R33/485 ,  G01R33/4833 ,  G01R33/5617

摘要： In MRS measurement using magnetic resonance highly precise results are efficiently obtained with coincidence of axes with axes in positioning image. In measurement according to the PRESS method for a plurality of regions each localized (specified) with a set of perpendicularly intersecting three slices, wherein one or two slices are common to the sets of three slices localizing the regions, and slices not common do not intersect, a slice not common to those of a region to be selectively excited is excited with a radio frequency magnetic field of which phase is different by 180 degrees from that of a radio frequency magnetic field used for exciting the region to be selectively excited a number of times equal to the number of common slices, and during the measurement of the region to be selectively excited, a group of regions other than the region to be selectively excited are thermally equilibrated.

摘要翻译： 在使用磁共振的MRS测量中，通过定位图像中的轴与轴的重合而有效地获得高精度结果。 在根据PRESS方法对多个区域进行测量，每个区域具有一组垂直相交的三个片段（指定），其中一个或两个切片对于定位该区域的三个切片的组是共同的，并且不共同的切片不相交 与被选择性地激励的区域不共同的切片被与用于激励该区域的射频磁场的相位相差180度的射频磁场激发，以选择性地激发多个 时间等于公共切片的数量，并且在要选择性激发的区域的测量期间，除了要选择性激发的区域之外的一组区域被热平衡。

公开(公告)号：US20130221968A1

公开(公告)日：2013-08-29

申请号：US13877702

申请日：2011-10-06

申请人： Hideta Habara ,  Yoshitaka Bito ,  Hisaaki Ochi ,  Yoshihisa Soutome ,  Masayoshi Dohata ,  Tetsuhiko Takahashi ,  Hiroyuki Takeuchi

发明人： Hideta Habara ,  Yoshitaka Bito ,  Hisaaki Ochi ,  Yoshihisa Soutome ,  Masayoshi Dohata ,  Tetsuhiko Takahashi ,  Hiroyuki Takeuchi

IPC分类号： G01R33/34

CPC分类号： G01R33/34092 ,  G01R33/288 ,  G01R33/34046 ,  G01R33/3456 ,  G01R33/3657 ,  G01R33/422 ,  H01Q9/065 ,  H01Q21/20

摘要： There is provided a technique for suppressing increase of SAR without sacrificing sensitivity in RF coils used in MRI apparatuses. The present invention provides an antenna device comprising a sheet-shaped conductor and a ribbon-shaped conductor disposed on the subject side with respect to the sheet-shaped conductor with a predetermined distance from the sheet-shaped conductor. The ribbon-shaped conductor has a meandering shape, and is adjusted so as to resonate at transmission and reception frequencies, and it is constituted so that distance to the sheet-shaped conductor becomes smaller at both end part thereof along the static magnetic field direction compared with the distance to the sheet-shaped conductor at the center thereof. Moreover, the ribbon-shaped conductor is constituted so as to have a smaller width, as the distance to the sheet-shaped conductor becomes smaller.

摘要翻译： 提供了抑制SAR增加的技术，而不牺牲MRI装置中使用的RF线圈的灵敏度。 本发明提供了一种天线装置，其包括片状导体和布置在与片状导体相距预定距离的片状导体的被检体侧的带状导体。 带状导体具有曲折形状，并且被调整为在发送和接收频率下谐振，并且其构造成使得沿着静磁场方向在其两端部处的与片状导体的距离变小 与其中心的片状导体的距离。 此外，随着与片状导体的距离变小，带状导体构成为具有较小的宽度。

公开(公告)号：US20120301007A1

公开(公告)日：2012-11-29

申请号：US13577355

申请日：2011-01-28

申请人： Toru Shirai ,  Yoshitaka Bito

发明人： Toru Shirai ,  Yoshitaka Bito

IPC分类号： G06K9/36

CPC分类号： G01R33/4828 ,  A61B5/055 ,  A61B5/4869 ,  A61B5/4872

摘要： Water/fat separation imaging is performed by an MRI device, even if the measurement is not performed with such echo times that the phases of water and fat signals become in-phase or out-of-phase. A determination is made as to which of two obtained separation images is a water image or a fat image. Two water/fat ratio maps are calculated from two original images obtained with such two echo times that phase differences of water and fat signals do not become positive and negative values, and do not becomes integral multiples of π. Two phase maps are calculated from the two water/fat ratio maps and are combined to calculate two minimum phase difference maps showing minimum spatial phase difference. From dispersion in differential maps obtained by spatially differentiating the minimum phase difference maps, a correct minimum phase difference map is determined, and is used to perform phase correction of the original image.

摘要翻译： 水分/脂肪分离成像由MRI装置进行，即使不进行水分和脂肪信号的相位成为同相或异相的回波时间的测量。 确定两个获得的分离图像中的哪一个是水图像或胖图像。 从两个回波时间获得的两个原始图像计算出两个水/脂肪比例图，其中水分和脂肪信号的相位差不会变为正值和负值，并不成为＆pgr的整数倍。 两个相位图由两个水/脂肪比图计算，并被组合以计算显示最小空间相位差的两个最小相位差图。 从通过空间微分最小相位差图获得的差分图中的色散，确定正确的最小相位差图，并用于执行原始图像的相位校正。

公开(公告)号：US08193810B2

公开(公告)日：2012-06-05

申请号：US12292449

申请日：2008-11-19

申请人： Yosuke Otake ,  Yoshihisa Soutome ,  Koji Hirata ,  Yoshitaka Bito

发明人： Yosuke Otake ,  Yoshihisa Soutome ,  Koji Hirata ,  Yoshitaka Bito

IPC分类号： G01V3/00

CPC分类号： G01R33/34046 ,  G01R33/34053 ,  G01R33/34069 ,  G01R33/341 ,  G01R33/3415 ,  G01R33/3635

摘要： An RF coil having at least three different resonance frequencies, wherein one of the resonance frequencies is adjusted to be a frequency fA of a magnetic resonance signal generated by a test subject, and the coil is adjusted so that ratio of difference between the frequency fA and a first frequency fB lower than fA and nearest to fA among the resonance frequencies (fA−fB), and difference between the frequency fA and a second resonance frequency fC higher than fA and nearest to the frequency fA among the resonance frequencies (fC−fA), should be from 0.5 to 2.0. There is provided a technique for receiving magnetic resonance signals always with high detection efficiency by an RF coil of an MRI apparatus even if significant loss is caused in the RF coil, or test subject is changed.

摘要翻译： 具有至少三个不同谐振频率的RF线圈，其中谐振频率之一被调整为由测试对象产生的磁共振信号的频率fA，并且调节线圈，使得频率fA与 在谐振频率（fA-fB）中比fA低且最接近fA的第一频率fB，以及频率fA与谐振频率（fC-fA）之间的最接近频率fA的fA的第二谐振频率fC之间的差 ），应为0.5〜2.0。 提供了一种用于通过MRI装置的RF线圈始终具有高检测效率的磁共振信号的技术，即使在RF线圈中引起显着的损失，或者测试对象发生变化。

公开(公告)号：US20110196225A1

公开(公告)日：2011-08-11

申请号：US13123299

申请日：2009-07-22

申请人： Satoshi Hirata ,  Yoshitaka Bito

发明人： Satoshi Hirata ,  Yoshitaka Bito

IPC分类号： A61B5/055

CPC分类号： G01R33/485 ,  G01R33/4833 ,  G01R33/5617

摘要： In the MRS measurement using magnetic resonance for performing measurement of two regions in the same section, highly precise results are efficiently obtained with coincidence of axes with axes in positioning image. In measurement according to the PRESS method for a plurality of regions each localized (specified) with a set of perpendicularly intersecting three slices, wherein one or two slices are common to the sets of three slices localizing the regions, and slices not common do not intersect, a slice not common to those of a region to be selectively excited is excited with a radio frequency magnetic field of which phase is different by 180 degrees from that of a radio frequency magnetic field used for exciting the region to be selectively excited a number of times equal to the number of common slices, and during the measurement of the region to be selectively excited, a group of regions other than the region to be selectively excited are thermally equilibrated.

摘要翻译： 在使用磁共振进行MRS测量的同一部分中的两个区域的测量中，通过定位图像中的轴与轴的一致性有效地获得高精度的结果。 在根据PRESS方法对多个区域进行测量，每个区域具有一组垂直相交的三个片段（指定），其中一个或两个切片对于定位该区域的三个切片的组是共同的，并且不共同的切片不相交 与被选择性地激励的区域不共同的切片被与用于激励该区域的射频磁场的相位相差180度的射频磁场激发，以选择性地激发多个 时间等于公共切片的数量，并且在要选择性激发的区域的测量期间，除了要选择性激发的区域之外的一组区域被热平衡。

公开(公告)号：US20110121834A1

公开(公告)日：2011-05-26

申请号：US13054474

申请日：2009-07-22

申请人： Yoshihisa Soutome ,  Hideta Habara ,  Yoshitaka Bito

发明人： Yoshihisa Soutome ,  Hideta Habara ,  Yoshitaka Bito

IPC分类号： G01R33/44

CPC分类号： G01R33/365 ,  G01R33/3415 ,  G01R33/3657

摘要： There is provided a high-frequency coil of an MRI device, which can easily and highly reproducibly reduce electromagnetic coupling between adjacent surface coils among a plurality of surface coils disposed with intervals. An electromagnetic decoupling coil that can generate a magnetic flux for canceling a magnetic flux generated by one of the adjacent surface coils and interlinking with the other surface coil is disposed between the adjacent surface coils. The electromagnetic decoupling coil is provided with a capacitor, and is tuned by means of the capacitor so that the electromagnetic coupling should be minimized in such a range that the resonance frequency thereof should be lower than the resonance frequency of the surface coils.

摘要翻译： 提供了一种MRI装置的高频线圈，其可以容易且高度可重复地减少间隔设置的多个表面线圈中的相邻表面线圈之间的电磁耦合。 可以在相邻的表面线圈之间设置电磁去耦线圈，该电磁去耦线圈可以产生用于消除由相邻的表面线圈之一产生的磁通并与另一个表面线圈相互连接的磁通量。 电磁去耦线圈设置有电容器，并通过电容器进行调谐，使得电磁耦合应在其共振频率应低于表面线圈的谐振频率的范围内最小化。

公开(公告)号：US20100272337A1

公开(公告)日：2010-10-28

申请号：US12741086

申请日：2008-07-07

申请人： Toru Shirai ,  Yoshitaka Bito ,  Yukari Yamamoto ,  Satoshi Hirata

发明人： Toru Shirai ,  Yoshitaka Bito ,  Yukari Yamamoto ,  Satoshi Hirata

IPC分类号： G06K9/00

CPC分类号： G01R33/56518 ,  G01R33/485 ,  G01R33/5618

摘要： While removing signals unnecessary for measuring signals from a metabolite, data required for eddy current correction are obtained in a short period of time. Signals from an unnecessary substance which is not an object of the measurement are removed, and phase data for correcting spectral distortion caused by an eddy current are obtained by a single measurement. Two kinds of frequency-selective pulses of which intensities are adjusted so that the signals from the unnecessary substance should have the same absolute values of intensities and opposite polarities are applied with changing intensities for every phase encoding for at least one axis, and the obtained signals are arranged in a k-space. By removing aliasing of image data obtained from the k-space data, signals from an unnecessary substance are removed, and phase data for eddy current correction are calculated by using a part of the k-space data.

摘要翻译： 在消除从代谢物测量信号所不必要的信号的同时，在短时间内获得涡流校正所需的数据。 除去不是测量对象的不必要物质的信号，并且通过单次测量获得用于校正由涡流引起的光谱失真的相位数据。 调整强度的两种频率选择脉冲，使得来自不需要的物质的信号应具有相同的强度绝对值和相反的极性，对于至少一个轴的每个相位编码的变化强度，并且获得的信号 被布置在k空间中。 通过去除从k空间数据获得的图像数据的混叠，去除来自不需要的物质的信号，并且通过使用k空间数据的一部分来计算用于涡流校正的相位数据。

公开(公告)号：US20070271214A1

公开(公告)日：2007-11-22

申请号：US11798889

申请日：2007-05-17

申请人： Shigeo Sumino ,  Tomohiro Yasuda ,  Yoshitaka Bito ,  Yoshiki Niwa

发明人： Shigeo Sumino ,  Tomohiro Yasuda ,  Yoshitaka Bito ,  Yoshiki Niwa

IPC分类号： G06F17/30

CPC分类号： G06F19/3456 ,  G06F16/40 ,  G06F19/326

摘要： A clinical trial support system suitable for the investigation of an adverse event or the like. A clinical trial database stores: information about sponsors; information about trial sites; product information including the product names, classification, chemical structure, and pharmacokinetics of trial drugs; trial information including trial name, target disease, phase, and completed status; contract information including trial site name, contracted number of cases, and completed status; trial subject information including sex, birth of date, height, weight, and completed status; and visit information including visit date, inspection result, and medical imaging data. An information control unit distributes a search interface for the analysis of an adverse event to the trial sponsor and a retrieval result to the trial site.

摘要翻译： 适用于不良事件等的调查的临床试验支援系统。 临床试验数据库存储：关于赞助商的信息; 有关试验场的信息; 产品信息，包括试药的产品名称，分类，化学结构和药代动力学; 试用信息包括试验名称，目标疾病，阶段和完成状态; 合同信息包括试验地点名称，合同案件数量和完成情况; 试验主题信息包括性别，出生日期，身高，体重和完成状态; 访问信息，包括访问日期，检查结果和医学影像数据。 信息控制单元将用于分析不良事件的搜索界面分发给试用发起者，并将检索结果分发到试用站点。