摘要:
An improved and highly efficient method for the preparation of 2-R(R=alkyl, aryl, H) pyrroles from nitrites (RCN, R=alkyl, aryl) is described using Lewis acid activated donor-acceptor cyclopropanes to react with aliphatic, aromatic, branched, α,β-unsaturated, or otherwise functionalized nitrites in a cascade [3+2] dipolar cycloaddition, dehydration and tautomerization sequence.
摘要:
Described herein are methods of producing kinesins. In a preferred embodiment, the kinesins are produced from a prokaryote, most preferably, a bacterial cell. Bacterial expression offers several advantages over systems previously utilized, such as, for example, Bacculovirus. The yield of protein is higher, the cost of the expression setup is lower, and creation of alternative expression vectors is easier. The concern of copurifying a contaminating activity from the expression host is also eliminated since bacteria, in contrast to the bacculovirus expression system, do not have kinesin like proteins. Also described herein are purified kinesins, preferably unglycosylated and methods of use.
摘要:
Provided are a device and system for generating a low frequency alternating electric field, and a signal regulating method. The device for generating a low frequency alternating electric field includes: a direct current power supply module, an input control module, a transformer, an output control module, and a discharge module. An output end of the direct current power supply module is coupled with an input end of the input control module. An output end of the input control module is coupled with a primary side winding of the transformer, one end of a secondary side winding of the transformer is coupled with an input end of the output control module, an output end of the output control module is coupled with the discharge module, and the other end of the secondary side winding of the transformer is coupled with a ground equipotential point.
摘要:
A head up display can be used in an automotive application and provides information for viewing above a glareshield or dashboard. The head up display includes a waveguide combiner and a compact projector. The waveguide combiner is at least partially disposed above the glareshield or dashboard and can provide dual axis pupil expansion. The waveguide combiner can present conformal or near conformal information and vehicle instrumentation information.
摘要:
A TE011 cavity filter assembly is disclosed. The system includes at least one resonator operating in TE011 mode having a resonant frequency. The at least one resonator may include a cavity comprising an inner diameter and a cavity length. The at least one resonator may also include a first metal disc inside the cavity. The first metal disc may include a disc diameter and a void in the metal disc, which includes a void diameter and a void depth. The inner diameter of the cavity may be greater than the disc diameter creating a gap with a gap width and a gap depth. The TE011 cavity filter assembly may further include positive coupling.
摘要:
Provided herein are compounds of formula I: wherein A, B, X, R1, R2 and subscript n are as defined in the following disclosure. Compositions comprising the compounds are also provided, as well as methods for their use, for example, in treatment of type 2 diabetes and type 2 diabetes-related conditions.