公开(公告)号：US20110228908A1

公开(公告)日：2011-09-22

申请号：US13149724

申请日：2011-05-31

Applicant: Michael GERTNER ,  Steven D. Hansen ,  Erik Chell

Inventor： Michael GERTNER ,  Steven D. Hansen ,  Erik Chell

IPC: A61N5/10

CPC classification number: A61N5/1067 ,  A61B6/506 ,  A61B6/508 ,  A61N5/10 ,  A61N5/1001 ,  A61N5/1017 ,  A61N5/1045 ,  A61N5/1048 ,  A61N5/1049 ,  A61N5/1064 ,  A61N5/1065 ,  A61N5/1077 ,  A61N5/1084 ,  A61N2005/1019 ,  A61N2005/1022 ,  A61N2005/105 ,  A61N2005/1051 ,  A61N2005/1059 ,  A61N2005/1091 ,  A61N2005/1097

Abstract: A radiosurgery system is described that delivers a therapeutic dose of radiation to a target structure in a patient. Some embodiments provide that, among other targets, ocular structures are treated. In some embodiments, the position of an ocular structure is tracked and related to a radiosurgery system. In some embodiments, a treatment plan is utilized for a specific disease to be treated and/or structures to be avoided. In some embodiments, radiodynamic therapy is described in which radiosurgery is used in combination with other treatments and can be delivered concomitant with, prior to, or following other treatments.

Abstract translation: 描述了放射外科系统，其将治疗剂量的辐射递送到患者中的目标结构。 一些实施例提供了除了其它目标之外，治疗眼部结构。 在一些实施例中，追踪眼结构的位置并与放射外科系统有关。 在一些实施方案中，治疗计划用于待治疗的特定疾病和/或要避免的结构。 在一些实施例中，描述了放射外科手术与其他治疗组合使用的放射治疗疗法，并且可以在其它治疗之前，之前或之后进行递送。

公开(公告)号：US20110178783A1

公开(公告)日：2011-07-21

申请号：US12929228

申请日：2011-01-10

Applicant: Norman Ronald Smith ,  Ivan Daniel Meir ,  Gideon Matthew Hale ,  Robert Edward Howe

Inventor： Norman Ronald Smith ,  Ivan Daniel Meir ,  Gideon Matthew Hale ,  Robert Edward Howe

IPC: G06F17/10

CPC classification number: G06T17/205 ,  A61N5/1049 ,  A61N2005/105 ,  A61N2005/1059 ,  G06T7/30 ,  G06T7/593 ,  G06T7/75 ,  G06T7/85 ,  G06T17/10 ,  G06T2200/08

Abstract: Three camera rigs are connected by wiring to a computer. The computer is also connected to a treatment apparatus. A mechanical couch is provided as part of the treatment apparatus such that under the control of the computer the relative positions of the mechanical couch and the treatment apparatus may be varied. The camera rigs obtain video images of a patient lying on the mechanical couch the computer processes these images to generate a three-dimensional model of the surface of the patient which is utilized to position the patient relative to the treatment apparatus.

Abstract translation: 三台摄像机通过接线连接到电脑。 计算机也连接到处理设备。 提供了作为处理设备的一部分的机械沙发，使得在计算机的控制下，机械沙发和处理设备的相对位置可以变化。 相机钻机获得躺在机械沙发上的患者的视频图像，计算机处理这些图像以产生用于使患者相对于治疗设备定位的患者表面的三维模型。

公开(公告)号：US20110038456A1

公开(公告)日：2011-02-17

申请号：US12912557

申请日：2010-10-26

Applicant: Michael GERTNER

Inventor： Michael GERTNER

IPC: A61N5/10

CPC classification number: A61N5/1049 ,  A61B6/506 ,  A61B2017/306 ,  A61F9/009 ,  A61N5/1017 ,  A61N5/103 ,  A61N2005/105 ,  A61N2005/1056 ,  A61N2005/1091

Abstract: A portable orthovoltage radiotherapy system is described that is configured to deliver a therapeutic dose of radiation to a target structure in a patient. In some embodiments, inflammatory ocular disorders are treated, specifically macular degeneration. In some embodiments, the ocular structures are placed in a global coordinate system based on ocular imaging. In some embodiments, the ocular structures inside the global coordinate system lead to direction of an automated positioning system that is directed based on the ocular structures within the coordinate system.

Abstract translation: 描述了便携式正电压放射治疗系统，其被配置为将治疗剂量的辐射递送到患者中的目标结构。 在一些实施方案中，治疗炎症性眼部疾病，特别是黄斑变性。 在一些实施例中，将眼部结构置于基于眼睛成像的全局坐标系中。 在一些实施例中，全局坐标系内的目镜结构导致基于坐标系内的眼睛结构而被引导的自动定位系统的方向。

公开(公告)号：US20100254513A1

公开(公告)日：2010-10-07

申请号：US12755373

申请日：2010-04-06

Applicant: Michael Gertner

Inventor： Michael Gertner

IPC: A61N5/10

CPC classification number: A61N5/1049 ,  A61B6/506 ,  A61B2017/306 ,  A61F9/009 ,  A61N5/1017 ,  A61N5/103 ,  A61N2005/105 ,  A61N2005/1056 ,  A61N2005/1091

Abstract: A radiosurgery system is described that is configured to deliver a therapeutic dose of radiation to a target structure in a patient. In some embodiments, inflammatory ocular disorders are treated, specifically macular degeneration. In some embodiments, the ocular structures are placed in a global coordinate system based on ocular imaging. In some embodiments, the ocular structures inside the global coordinate system lead to direction of an automated positioning system that is directed based on the ocular structures within the coordinate system. In some embodiments, the position of the ocular structure is tracked and related to the status of the radiosurgery system. In some embodiments, a treatment plan is utilized in which beam energy and direction and duration of time for treatment is determined for a specific disease to be treated and/or structures to be avoided. In some embodiments, the structure is an eye and the eye is tracked by the system. In some embodiments, the eye is held in place and in some embodiments, the eye is fixed by the patient. In some embodiments, a fiducial is placed on the eye to aid in positioning. In some embodiments, a reflection off the eye is used to aid in positioning. In some embodiments, radiodynamic therapy is described in which radiosurgery is used in combination with other treatments and can be delivered concomitant with, prior to, or following other treatments.

公开(公告)号：US07697147B2

公开(公告)日：2010-04-13

申请号：US12132874

申请日：2008-06-04

Applicant: Johann Kindlein

Inventor： Johann Kindlein

IPC: G01B11/24

CPC classification number: A61B6/08 ,  A61B6/032 ,  A61B6/548 ,  A61B2090/366 ,  A61N5/1049 ,  A61N2005/105 ,  A61N2005/1059

Abstract: An apparatus for the representation of an area on the three-dimensional surface of a patient's body, with a control device which provides three-dimensional coordinates of at least one area to be represented on the surface of the patient's body, wherein the area pre-sets a desired intersection area of a radiation area on the surface of the patient's body, characterized in that at least one projection device featuring a laser is provided, by which the desired intersection area can be projected to the three-dimensional surface of the patient's body on the basis of the provided coordinates, while at least one laser beam generated by the laser can be guided along the contour of the desired intersection area sufficiently rapidly, so that the impression of a closed contour around the desired intersection area results.

Abstract translation: 一种用于表示患者身体的三维表面上的区域的装置，具有提供要表示在患者身体的表面上的至少一个区域的三维坐标的控制装置，其中， 设置患者身体表面上的辐射区域的期望的交叉区域，其特征在于，提供具有激光器的至少一个投影装置，通过该投影装置可以将期望的交叉区域投影到患者身体的三维表面 基于所提供的坐标，同时由激光器产生的至少一个激光束可以沿着期望的交叉区域的轮廓充分快速地被引导，从而导致围绕期望的交叉区域的封闭轮廓的印象。

公开(公告)号：US07693260B2

公开(公告)日：2010-04-06

申请号：US12100398

申请日：2008-04-09

Applicant: Michael Gertner ,  Steven D. Hansen

Inventor： Michael Gertner ,  Steven D. Hansen

IPC: A61N5/10

CPC classification number: A61N5/1067 ,  A61B6/506 ,  A61B6/508 ,  A61N5/10 ,  A61N5/1001 ,  A61N5/1017 ,  A61N5/1045 ,  A61N5/1048 ,  A61N5/1049 ,  A61N5/1064 ,  A61N5/1065 ,  A61N5/1077 ,  A61N5/1084 ,  A61N2005/1019 ,  A61N2005/1022 ,  A61N2005/105 ,  A61N2005/1051 ,  A61N2005/1059 ,  A61N2005/1091 ,  A61N2005/1097

Abstract: A radiosurgery system is described that delivers a therapeutic dose of radiation to a target structure in a patient. In some embodiments, inflammatory ocular disorders are treated, specifically macular degeneration. In some embodiments, ocular structures are placed in a global coordinate system, based on ocular imaging, which leads to direction of an automated positioning system. In some embodiments, the position of an ocular structure is tracked and related to a radiosurgery system. In some embodiments, a treatment plan is utilized for a specific disease to be treated and/or structures to be avoided. In some embodiments, a fiducial aids in positioning the system. In some embodiments, a reflection off the eye is used to aid in positioning. In some embodiments, radiodynamic therapy is described in which radiosurgery is used in combination with other treatments and can be delivered concomitant with, prior to, or following other treatments.

Abstract translation: 描述了放射外科系统，其将治疗剂量的辐射递送到患者中的目标结构。 在一些实施方案中，治疗炎症性眼部疾病，特别是黄斑变性。 在一些实施例中，眼睛结构被放置在基于眼睛成像的全局坐标系中，其导致自动定位系统的方向。 在一些实施例中，追踪眼结构的位置并与放射外科系统有关。 在一些实施方案中，治疗计划用于待治疗的特定疾病和/或要避免的结构。 在一些实施例中，基准有助于定位系统。 在一些实施例中，使用眼睛的反射来帮助定位。 在一些实施例中，描述了放射外科手术与其他治疗组合使用的放射治疗疗法，并且可以在其它治疗之前，之前或之后进行递送。

公开(公告)号：US20100067657A1

公开(公告)日：2010-03-18

申请号：US12538087

申请日：2009-08-07

Applicant: Michael Gertner ,  Steven D. Hansen ,  Erik Chell

Inventor： Michael Gertner ,  Steven D. Hansen ,  Erik Chell

IPC: A61N5/10

CPC classification number: A61N5/1067 ,  A61B6/506 ,  A61B6/508 ,  A61N5/10 ,  A61N5/1001 ,  A61N5/1017 ,  A61N5/1045 ,  A61N5/1048 ,  A61N5/1049 ,  A61N5/1064 ,  A61N5/1065 ,  A61N5/1077 ,  A61N5/1084 ,  A61N2005/1019 ,  A61N2005/1022 ,  A61N2005/105 ,  A61N2005/1051 ,  A61N2005/1059 ,  A61N2005/1091 ,  A61N2005/1097

Abstract: A radiosurgery system is described that is configured to deliver a therapeutic dose of radiation to a target structure in a patient. In some embodiments, inflammatory ocular disorders are treated, specifically macular degeneration. In some embodiments, other disorders or tissues of a body are treated with the dose of radiation. In some embodiments, the target tissues are placed in a global coordinate system based on ocular imaging. In some embodiments, the target tissues inside the global coordinate system lead to direction of an automated positioning system that is directed based on the target tissues within the coordinate system. In some embodiments, a treatment plan is utilised in which beam energy and direction and duration of time for treatment is determined for a specific disease to be treated and/or structures to be avoided. In some embodiments, a fiducial marker is used to identify the location of the target tissues. In some embodiments, radiodynamic therapy is described in which radiosurgery is used in combination with other treatments and can be delivered concomitant with, prior to, or following other treatments.

公开(公告)号：US07657303B2

公开(公告)日：2010-02-02

申请号：US10743531

申请日：2003-12-22

Applicant: Timothy P. Mate ,  Steven C. Dimmer

Inventor： Timothy P. Mate ,  Steven C. Dimmer

IPC: A61B5/05 ,  A61N5/10 ,  A61B19/00

CPC classification number: A61N5/1049 ,  A61B34/20 ,  A61B2034/2051 ,  A61B2034/2072 ,  A61B2090/3958 ,  A61N5/107 ,  A61N2005/105 ,  A61N2005/1051

Abstract: A system and method for accurately locating and tracking the position of a target, such as a tumor or the like, within a body. In one embodiment, the system is a target locating and monitoring system usable with a radiation delivery source that delivers selected doses of radiation to a target in a body. The system includes one or more excitable markers positionable in or near the target, an external excitation source that remotely excites the markers to produce an identifiable signal, and a plurality of sensors spaced apart in a known geometry relative to each other. A computer is coupled to the sensors and configured to use the marker measurements to identify a target isocenter within the target. The computer compares the position of the target isocenter with the location of the machine isocenter. The computer also controls movement of the patient and a patient support device so the target isocenter is co-incident with the machine isocenter before and during radiation therapy.

Abstract translation: 一种用于在身体内准确定位和跟踪诸如肿瘤等的靶的位置的系统和方法。 在一个实施例中，该系统是可与辐射递送源一起使用的目标定位和监测系统，其将选定剂量的辐射递送到身体中的目标。 该系统包括可定位在靶内或附近的一个或多个可激发标记，远程激发标记以产生可识别信号的外部激发源以及以已知几何形状相对于彼此间隔开的多个传感器。 计算机耦合到传感器并且被配置为使用标记测量来识别目标内的目标等角点。 计算机将目标等角点的位置与机器等角点的位置进行比较。 计算机还控制患者和患者支撑装置的运动，使得靶放射线与放射治疗之前和放射治疗期间的机器等角点共同入射。

公开(公告)号：US20100002837A1

公开(公告)日：2010-01-07

申请号：US12497437

申请日：2009-07-02

Applicant: Michael GERTNER ,  Steven D. Hansen

Inventor： Michael GERTNER ,  Steven D. Hansen

IPC: A61N5/10

CPC classification number: A61N5/1067 ,  A61B6/506 ,  A61B6/508 ,  A61N5/10 ,  A61N5/1001 ,  A61N5/1017 ,  A61N5/1045 ,  A61N5/1048 ,  A61N5/1049 ,  A61N5/1064 ,  A61N5/1065 ,  A61N5/1077 ,  A61N5/1084 ,  A61N2005/1019 ,  A61N2005/1022 ,  A61N2005/105 ,  A61N2005/1051 ,  A61N2005/1059 ,  A61N2005/1091 ,  A61N2005/1097

Abstract: A radiosurgery system is described that is configured to deliver a therapeutic dose of radiation to a target structure in a patient. In some embodiments, inflammatory ocular disorders are treated, specifically macular degeneration. In some embodiments, other disorders or tissues of a body are treated with the dose of radiation. In some embodiments, the target tissues are placed in a global coordinate system based on ocular imaging. In some embodiments, the target tissues inside the global coordinate system lead to direction of an automated positioning system that is directed based on the target tissues within the coordinate system. In some embodiments, a treatment plan is utilized in which beam energy and direction and duration of time for treatment is determined for a specific disease to be treated and/or structures to be avoided. In some embodiments, a fiducial marker is used to identify the location of the target tissues. In some embodiments, radiodynamic therapy is described in which radiosurgery is used in combination with other treatments and can be delivered concomitant with, prior to, or following other treatments.

Abstract translation: 描述了放射外科系统，其被配置为将治疗剂量的辐射递送到患者中的目标结构。 在一些实施方案中，治疗炎症性眼部疾病，特别是黄斑变性。 在一些实施方案中，身体的其它病症或组织用辐射剂量治疗。 在一些实施例中，目标组织基于眼睛成像被放置在全局坐标系中。 在一些实施例中，全局坐标系统内的目标组织导致基于坐标系统内的目标组织定向的自动定位系统的方向。 在一些实施例中，使用治疗计划，其中针对要治疗的特定疾病和/或要避免的结构确定束能量和治疗时间的方向和持续时间。 在一些实施方案中，使用基准标记来鉴定靶组织的位置。 在一些实施例中，描述了放射外科手术与其他治疗组合使用的放射治疗疗法，并且可以在其它治疗之前，之前或之后进行递送。

公开(公告)号：US20090251709A1

公开(公告)日：2009-10-08

申请号：US12132874

申请日：2008-06-04

Applicant: Johann Kindlein

Inventor： Johann Kindlein

IPC: G01B11/25 ,  G01B11/24

CPC classification number: A61B6/08 ,  A61B6/032 ,  A61B6/548 ,  A61B2090/366 ,  A61N5/1049 ,  A61N2005/105 ,  A61N2005/1059

Abstract: An apparatus for the representation of an area on the three-dimensional surface of a patient's body, with a control device which provides three-dimensional coordinates of at least one area to be represented on the surface of the patient's body, wherein the area pre-sets a desired intersection area of a radiation area on the surface of the patient's body, characterised in that at least one projection device featuring a laser is provided, by which the desired intersection area can be projected to the three-dimensional surface of the patient's body on the basis of the provided coordinates, while at least one laser beam generated by the laser can be guided along the contour of the desired intersection area sufficiently rapidly, so that the impression of a closed contour around the desired intersection area results.

Abstract translation: 一种用于表示患者身体的三维表面上的区域的装置，具有提供要表示在患者身体的表面上的至少一个区域的三维坐标的控制装置，其中， 设置患者身体表面上的辐射区域的期望的交叉区域，其特征在于，提供具有激光器的至少一个投影装置，通过该投影装置可以将期望的交叉区域投影到患者身体的三维表面 基于所提供的坐标，同时由激光器产生的至少一个激光束可以沿着期望的交叉区域的轮廓充分快速地被引导，从而导致围绕期望的交叉区域的封闭轮廓的印象。