中科微点-全球专利检索

  1. Login
  2. Sign Up

Search Results

161 records (took 0.017 seconds)

    Synthesis, polymerization and quaternization of N-substituted acrylamidines
    74.
    发明授权
    Synthesis, polymerization and quaternization of N-substituted acrylamidines 失效
    N-取代的丙烯酰胺的合成，聚合和季铵化

    公开(公告)号：US3954863A

    公开(公告)日：1976-05-04

    申请号：US358357

    申请日：1973-05-08

    Applicant: Robert Fuks

    Inventor： Robert Fuks

    IPC: C08F26/02 ,  C07C123/00

    CPC classification number: C08F26/02 ,  Y10S526/923

    Abstract: N-substituted acrylamidines, a new class of acrylic monomers, are synthesized by the process of this invention which comprises successively contacting with an acrylonitrile or derivative thereof (a) a Lewis acid catalyst, (b) an alkyl halide and (c) an amine. Novel polyacrylamidines as well as quaternary salts of polyacrylamidines are disclosed. Due to their basic nature the N-substituted acrylamidines are useful for introducing basic groups into polymers.

    Abstract translation: 通过本发明的方法合成N-取代的丙烯酰胺，一类新的丙烯酸类单体，其包括与丙烯腈或其衍生物（a）路易斯酸催化剂，（b）烷基卤和（c）胺 。 公开了新型聚丙烯酰胺和聚丙烯酰胺的季盐。 由于其基本性质，N-取代的丙烯酰胺可用于将碱性基团引入聚合物。

    N,n{40 ,n{41 ,n{41 {40 -tetrasubstituted malonamidines and salts
    75.
    发明授权
    N,n{40 ,n{41 ,n{41 {40 -tetrasubstituted malonamidines and salts 失效
    N，n {40，n {41，n {41 {40-四取代的丙二酰胺和盐

    公开(公告)号：US3929882A

    公开(公告)日：1975-12-30

    申请号：US21793372

    申请日：1972-01-13

    Applicant: DU PONT

    Inventor： HERKES FRANK EDWARD

    IPC: C07D235/20 ,  C07C123/00

    CPC classification number: C07D235/20

    Abstract: WHEREIN: R and R'', alike or different, are selected from hydrocarbyl groups of 1 to 14 carbons and monosubstituted hydrocarbyl groups of 1 to 14 carbons, adjacent R'' groups can be a hydrocarbyl 2 carbon chain diradical, and X is chlorine or fluorine. Also disclosed are the free bases formed by treating the salt with a base. The salt compounds are prepared by reaction of RC(CF2X) CF2 with a primary amine.
    Disclosed herein are compounds (salts) of the formula

    Abstract translation: 本文公开的是下式的化合物（盐）：WHEREIN：

    Aminophenylamidines, their production and their pharmaceutical use
    76.
    发明授权
    Aminophenylamidines, their production and their pharmaceutical use 失效
    氨基苯基脒，其生产及其药用

    公开(公告)号：US3911010A

    公开(公告)日：1975-10-07

    申请号：US39869273

    申请日：1973-09-19

    Applicant: BAYER AG

    Inventor： WOLLWEBER HARTMUND ,  FLUCKE WINFRIED

    IPC: C07C259/14 ,  C07D209/42 ,  C07C123/00

    CPC classification number: C07C259/14 ,  C07D209/42

    Abstract: The present invention relates to new aminophenylamidines, to processes for their production, and to their pharmaceutical use. These new compounds are useful as paraciticides, especially as anthelmintics. Some acylaminophenylformamidines, such as N-(p-acetamidophenyl)N'',N''-dimethylformamidine (U.S. Pat. No. 3,184,482) and N-phenylacetamidines, such as N-(p-chlorophenyl)-N'',N''dimethylacetamidine, are already known. These compounds are however inactive against the helminths mentioned below.

    Abstract translation: 本发明涉及新的氨基苯基脒，其制备方法及其药物用途。 这些新化合物可用作杀螨剂，特别是作为驱肠虫剂。

    Chlorinated mandelamidines
    77.
    发明授权
    Chlorinated mandelamidines 失效
    氯化扁桃酰脒

    公开(公告)号：US3899533A

    公开(公告)日：1975-08-12

    申请号：US41777273

    申请日：1973-11-21

    Applicant: ORSYMONDE

    Inventor： SOUCHARD MADDY

    IPC: C07C67/00 ,  C07C239/00 ,  C07C257/14 ,  C07C259/14 ,  C07D213/79 ,  C07D233/22 ,  C07D239/06 ,  C07C123/00

    CPC classification number: C07D239/06 ,  C07C259/14 ,  C07D233/22

    Abstract: New chlorinated derivatives of mandelamidine and acid addition salts thereof are produced by reacting a mandeliminoalkyl ether of the formula

    in which A is alkyl lower alkyl group, preferably C1-C2, and X, Y, Z represent H or Cl, one at least of the X, Y and Z being a chlorine atom, or one of the acid addition salts of the said mandeliminoalkyl ether, preferably the hydrochloride, with an amine of the formula

    Abstract translation: 通过使式NH CHOH-C ANGLE OA的烷基亚氨基烷基醚（其中A是烷基低级烷基，优选C 1 -C 2）与X，Y，Z表示H或Cl 至少X，Y和Z中的至少一个为氯原子，或所述扁桃酰烷基醚，优选盐酸盐的酸加成盐之一与式HNR1R'2的胺，其中R1如上定义， R'2表示氢原子，C1-C5低级烷基，NH2基，OH基，R'2可以是（CH2）nNH2基，其中n是2的整数 或当R1 = H时为3，如果需要，当R2不同于OH时，由此获得的产物进行用于引入基团R =酰基的酯化反应。 这些新衍生物特别适用于治疗高血压。

    Pseudothiuronium compounds
    78.
    发明授权
    Pseudothiuronium compounds 失效
    假硫脲化合物

    公开(公告)号：US3891704A

    公开(公告)日：1975-06-24

    申请号：US31830272

    申请日：1972-12-26

    Applicant: RORER INC WILLIAM H

    Inventor： DIAMOND JULIUS

    IPC: C07C335/32 ,  C07C123/00

    CPC classification number: C07C335/32 ,  Y10S514/927

    Abstract: Novel pseudothiuronium compounds and processes for their preparation are described. These compounds have gastric antisecretory, spasmolytic and anti-ulcerogenic properties. A method for the treatment of gastrointestinal hyperacidity and ulceration is also disclosed.

    Abstract translation: 描述了新颖的假硫脲化合物及其制备方法。 这些化合物具有胃的抗分泌，解痉和抗溃疡的特性。 还公开了治疗胃肠胃酸过多和溃疡的方法。

    {107 -(3-Hydroxyphenyl)substituted amidines and derivatives thereof as anthelmintic agents
    79.
    发明授权
    {107 -(3-Hydroxyphenyl)substituted amidines and derivatives thereof as anthelmintic agents 失效
    {107-（3-羟基苯基）取代的脒及其衍生物作为驱肠剂

    公开(公告)号：US3891698A

    公开(公告)日：1975-06-24

    申请号：US7577670

    申请日：1970-09-25

    Applicant: PFIZER

    Inventor： MCFARLAND JAMES W

    IPC: C07C59/52 ,  C07C65/03 ,  C07C259/14 ,  C07D233/22 ,  C07D233/24 ,  C07D239/06 ,  C07C123/00

    CPC classification number: C07D239/06 ,  C07C59/52 ,  C07C65/03 ,  C07C259/14 ,  C07D233/22 ,  C07D233/24

    Abstract: The preparation and anthelmintic properties of certain omega (3-R-O-phenyl) substituted cyclic and acyclic amidines; namely, 1,4,5,6-tetrahydro-2-(2-(3-R-O-phenyl)ethyl)pyrimidines, 1,4,5,6tetrahydro-2-(2-(3-R-O-phenyl)vinyl)pyrimidines and the corresponding 2-imidazolines; and N-methyl-N-substituted 3-(3-RO-phenyl) propionamidines and the corresponding acrylamidines wherein R-O- is hydroxy or a group convertible to hydroxy, is described.

    Abstract translation: 某些ω-（3-R-O-苯基）取代的环状和非环状脒的制备和驱虫特性; 即1,4,5,6-四氢-2- [2-（3-RO-苯基）乙基]嘧啶，1,4,5,6-四氢-2- [2-（3-RO-苯基） 乙烯基]嘧啶和相应的2-咪唑啉; 和N-甲基-N-取代的3-（3-R-O-苯基）丙酰胺和其中R-O-是羟基或可转化成羟基的基团的相应的丙烯酰胺。

    (di-(ortho substituted)-phenyl)alkylisothiosemicarbazides and derivatives
    80.
    发明授权
    (di-(ortho substituted)-phenyl)alkylisothiosemicarbazides and derivatives 失效
    （DI-（ORTHO取代） - 苯基）烷基硫代酪氨酸和衍生物

    公开(公告)号：US3845125A

    公开(公告)日：1974-10-29

    申请号：US36330273

    申请日：1973-05-23

    Applicant: SEARLE & CO

    Inventor： TWEIT R

    IPC: C07C337/08 ,  C07C67/00 ,  C07C325/00 ,  C07C123/00

    CPC classification number: C07C335/32 ,  Y10S514/821

    Abstract: 1. A MEMBER SELECTED FROM THE GROUP CONSISTING OF COMPOUNDS OF THE FORMULA (2-X2,4-X1,6-X3-PHENYL)-(CH2)N-S-C(-NH2)=N-N=R WHEREIN X1 IS HYDROGEN, HALO, OR LOWER ALKYL; X2 AND X3 ARE HALO OR LOWER ALKYL; N=1-7; AND R IS H2 OR AN ALKYLIDENE RADICAL OF THE FORMULA

    =C(-R1)-R2

    WHEREIN A1 AND A2 ARE LOWER ALKYL OR PHENYL, OR A1 AND A2 ARE TAKEN TOGETHER TO FORM CYCLOALKYLENE RADICALS HAVING 5-12 CARBON ATOMS AND SALTS THEREOF OF PHARMACEUTICALLY ACCEPTABLE ACIDS.

Patent Agency Ranking