公开(公告)号：US20030032921A1

公开(公告)日：2003-02-13

申请号：US09924783

申请日：2001-08-07

申请人： Advanced Cardiovascular Systems, Inc.

发明人： Jacky G. Duchamp

IPC分类号： A61M029/00

CPC分类号： A61M25/1036 ,  A61M25/001 ,  A61M25/0069 ,  A61M25/1006 ,  A61M2025/1093

摘要： A balloon catheter having a distal end, including an elongated catheter shaft having a proximal end, a distal end, a proximal shaft section, a distal shaft section, a guidewire receiving lumen extending along at least a portion thereof to a port at the catheter shaft distal end, and an inflation lumen; a balloon on the distal catheter shaft section and having an inflatable interior in fluid communication with the inflation lumen, proximal and distal ends, a proximal balloon shaft section adjacent the balloon proximal end, and a distal balloon shaft section adjacent the balloon distal end and being adhesively secured to the catheter shaft; and a tip member on the distal end of the catheter having proximal and distal ends; and being in fluid communication with the catheter shaft guidewire receiving lumen; the proximal end adhesively joined to the balloon distal shaft section and the catheter shaft.

摘要翻译： 一种气囊导管，其具有远端，包括细长的导管轴，其具有近端，远端，近端轴部分，远端轴部分，沿其至少一部分延伸到导管轴端口处的导丝接收腔 远端和充气腔; 在远侧导管轴部分上的气囊，并且具有与充气腔，近端和远端流体连通的可充气内部，邻近球囊近端的近端球轴部分和与球囊远端相邻的远端球轴部分， 粘合地固定到导管轴; 并且在所述导管的远端上具有近端和远端的尖端构件; 并且与导管轴导丝接收管腔流体连通; 所述近端粘合地接合到所述球囊远侧轴部和所述导管轴。

公开(公告)号：US20020187288A1

公开(公告)日：2002-12-12

申请号：US09879023

申请日：2001-06-11

申请人： Advanced Cardiovascular Systems, Inc.

发明人： Florencia Lim ,  Christopher J. Buchko ,  Ashok A. Shah ,  Murthy V. Simhambhatla

IPC分类号： B32B001/08

CPC分类号： A61L31/146 ,  A61F2/07 ,  A61F2002/072 ,  A61L27/18 ,  A61L27/56 ,  A61L29/06 ,  A61L29/146 ,  A61L31/06 ,  Y10T428/1334 ,  Y10T428/139 ,  C08L75/04

摘要： A medical device, and particularly an intracorporeal device for therapeutic or diagnostic use, comprising a silicone polyurethane. One embodiment of the invention is a medical device having a body formed of melt process extruded, porous silicone polyurethane material. In a method of the invention, the silicone polyurethane is combined with a porogen and then melt process extruded into a desired shape such as a tubular body. The porogen is then extracted from the extrudate, to form the extruded, melt processed, porous silicone polyurethane tubular body. The medical device, such as a stent cover, vascular graft, or catheter balloon, formed of the silicone polyurethane has excellent biostability, strength, and flexibility.

摘要翻译： 医疗装置，特别是用于治疗或诊断用途的体内器械，其包含硅氧烷聚氨酯。 本发明的一个实施方案是具有由熔融加工挤出的多孔硅氧烷聚氨酯材料形成的主体的医疗装置。 在本发明的方法中，将硅氧烷聚氨酯与致孔剂组合，然后熔融加工成挤出成所需形状如管状体。 然后从挤出物中提取致孔剂，以形成挤出的熔融加工的多孔硅氧烷聚氨酯管体。 由硅氧烷聚氨酯形成的医疗装置，例如支架盖，血管移植物或导管球囊具有优异的生物稳定性，强度和柔韧性。

公开(公告)号：US20020142039A1

公开(公告)日：2002-10-03

申请号：US09822952

申请日：2001-03-30

申请人： Advanced Cardiovascular Systems, Inc.

发明人： Charles David Claude

IPC分类号： A61K009/14

CPC分类号： A61K9/0024

摘要： The present invention includes a drug release system. The drug release system comprises a bulk polymer phase and a polymeric drug-enriched phase within the bulk polymer phase. At least one drug is incorporated into the drug-enriched phase.

摘要翻译： 本发明包括药物释放系统。 药物释放系统包括本体聚合物相和本体聚合物相内的聚合物药物富集相。 至少一种药物掺入药物富集阶段。

公开(公告)号：US20020082550A1

公开(公告)日：2002-06-27

申请号：US10001878

申请日：2001-11-19

申请人： Advanced Cardiovascular Systems, Inc.

发明人： Rasean L. Hamilton ,  Teresita R. Baerga

IPC分类号： A61M029/00

CPC分类号： A61M25/0069 ,  A61M2025/0081 ,  A61M2025/1093

摘要： An intraluminal catheter comprising an elongated catheter shaft having proximal and distal ends and at least one lumen, and a tip member on a distal end of the catheter having a proximal end spaced distally apart from the distal end of the catheter shaft.

公开(公告)号：US20020077691A1

公开(公告)日：2002-06-20

申请号：US09740116

申请日：2000-12-18

申请人： ADVANCED CARDIOVASCULAR SYSTEMS, INC.

发明人： John C. Nachtigall

IPC分类号： A61F002/06

CPC分类号： A61F2/966 ,  A61F2/90 ,  A61F2/95 ,  A61F2002/821

摘要： An expandable stent to be positioned and implanted at the intersection of a great vessel and a branch vessel. A deployable stop engages the wall of the great vessel surrounding the ostium and the stent body extends into and is implanted in a branch vessel. A sheath holds the stent in a compressed state during delivery and a retainer holds the stop in an undeployed position while the delivery system is advanced to a desired location at the intersection of the great vessel and the branch vessel.

摘要翻译： 可扩张的支架被定位和植入在大血管和分支血管的交叉处。 可展开的止动件接合围绕口的大容器的壁，并且支架体延伸到并且植入分支容器中。 护套在输送期间将支架保持在压缩状态，并且保持器将止挡保持在未部署位置，同时输送系统前进到大血管和分支血管的交叉点处的期望位置。

公开(公告)号：US20010011158A1

公开(公告)日：2001-08-02

申请号：US09815912

申请日：2001-03-23

申请人： Advanced Cardiovascular Systems, Inc.

发明人： Johathan M. Howland

IPC分类号： A61B005/00

CPC分类号： A61M25/09 ,  A61M2025/09175

摘要： A method of joining two members of a medical device wherein at least one of the members has a thin layer of joinable material deposited on the surface thereof by vapor deposition, preferably, physical vapor deposition. A guidewire for advancement of intraluminal medical devices may be manufactured by depositing a thin layer of joinable material on the surface of a component which is made from a reactive alloy with a tenacious oxide layer. The thin layer of joinable material facilitates joining difficult to bond materials with other components of the guidewire. Physical vapor deposition may also be used to treat components of medical devices, such as distal guidewire segments, in order to alter their mechanical properties. Specifically, a pseudoelastic alloy segment may be made shapeable by vapor deposition of a non-pseudoelastic metal thereon.