公开(公告)号：US20020187288A1

公开(公告)日：2002-12-12

申请号：US09879023

申请日：2001-06-11

Applicant: Advanced Cardiovascular Systems, Inc.

Inventor： Florencia Lim ,  Christopher J. Buchko ,  Ashok A. Shah ,  Murthy V. Simhambhatla

IPC: B32B001/08

CPC classification number: A61L31/146 ,  A61F2/07 ,  A61F2002/072 ,  A61L27/18 ,  A61L27/56 ,  A61L29/06 ,  A61L29/146 ,  A61L31/06 ,  Y10T428/1334 ,  Y10T428/139 ,  C08L75/04

Abstract: A medical device, and particularly an intracorporeal device for therapeutic or diagnostic use, comprising a silicone polyurethane. One embodiment of the invention is a medical device having a body formed of melt process extruded, porous silicone polyurethane material. In a method of the invention, the silicone polyurethane is combined with a porogen and then melt process extruded into a desired shape such as a tubular body. The porogen is then extracted from the extrudate, to form the extruded, melt processed, porous silicone polyurethane tubular body. The medical device, such as a stent cover, vascular graft, or catheter balloon, formed of the silicone polyurethane has excellent biostability, strength, and flexibility.

Abstract translation: 医疗装置，特别是用于治疗或诊断用途的体内器械，其包含硅氧烷聚氨酯。 本发明的一个实施方案是具有由熔融加工挤出的多孔硅氧烷聚氨酯材料形成的主体的医疗装置。 在本发明的方法中，将硅氧烷聚氨酯与致孔剂组合，然后熔融加工成挤出成所需形状如管状体。 然后从挤出物中提取致孔剂，以形成挤出的熔融加工的多孔硅氧烷聚氨酯管体。 由硅氧烷聚氨酯形成的医疗装置，例如支架盖，血管移植物或导管球囊具有优异的生物稳定性，强度和柔韧性。