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81.发明申请公开(公告)号：US20170239214A1
公开(公告)日：2017-08-24
申请号：US15503968
申请日：2015-10-13
Applicant: The Asan Foundation
Inventor： Ki Up Lee , Joong Yeol Park , Eun Hee Koh , Jung Eun Jang , In Kyu Lee
IPC: A61K31/385 , A23L33/175 , A23L33/12 , A23L33/00 , A61K31/198 , A61K9/00
CPC classification number: A61K31/385 , A23L33/10 , A23L33/12 , A23L33/175 , A23L33/40 , A23V2002/00 , A61K9/0019 , A61K9/0095 , A61K9/08 , A61K9/145 , A61K9/2018 , A61K9/4858 , A61K31/198 , A23V2200/332 , A23V2250/026 , A23V2250/0634 , A23V2250/156 , A23V2250/1578 , A23V2250/1592 , A23V2250/16 , A23V2250/161 , A23V2250/1618 , A23V2250/1642 , A23V2250/702 , A23V2250/7042 , A23V2250/7044 , A23V2250/7052 , A23V2250/7056 , A23V2250/706 , A23V2250/708 , A23V2250/712 , A23V2250/72
Abstract: The present invention provides a composition containing α-lipoic acid and N-acetylcysteine as active ingredients. The mixed composition of α-lipoic acid and N-acetylcysteine of the present invention can reduce a risk of side effects due to drugs with synergetic effects due to merge administration of two drugs, and can be usefully used for preventing or treating obesity with excellent effects of inhibiting a weight gain compared to each single composition containing α-lipoic acid or N-acetylcysteine.
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82.发明申请METHOD FOR DISTINGUISHING PULMONARY ARTERY AND PULMONARY VEIN, AND METHOD FOR QUANTIFYING BLOOD VESSELS USING SAME 有权肺动脉血管和肺动脉分离术的方法及使用其定量血管的方法公开(公告)号：US20160117814A1
公开(公告)日：2016-04-28
申请号：US14881817
申请日：2015-10-13
Applicant: The Asan Foundation
Inventor： Nam Kug Kim , Joon Beom Seo , Se Youn Park , Sang Min Lee
CPC classification number: G06T7/0012 , A61B6/032 , A61B6/504 , A61B6/5217 , G06K9/4604 , G06K9/4638 , G06K9/469 , G06K9/52 , G06K9/6267 , G06K9/6857 , G06K2009/4666 , G06K2209/051 , G06T2200/04 , G06T2207/30061 , G06T2207/30101
Abstract: A method for distinguishing between pulmonary arteries and pulmonary veins and a method for quantifying blood vessels are disclosed. The method for distinguishing between pulmonary arteries and pulmonary veins includes: forming a set of pulmonary vessels for points corresponding to pulmonary vessels, wherein each of the points of the set of pulmonary vessels has weight information; forming a tree from the points of the set of pulmonary vessels by using the weight information; and distinguishing between the pulmonary arteries and the pulmonary veins by separating the tree into a plurality of regions. The method for quantifying blood vessels includes: extracting blood vessels as a three-dimensional set of voxels based on medical images of an organ; finding the voxels of blood vessels included in a region of interest of the organ; and quantifying length information of the blood vessels by using the found voxels.
Abstract translation: 公开了一种用于区分肺动脉和肺静脉的方法以及用于定量血管的方法。 用于区分肺动脉和肺静脉的方法包括：形成一组对应于肺血管的点的肺血管，其中该组肺动脉血管的每个点具有体重信息; 通过使用权重信息从该组肺血管的点形成树; 并通过将树分离成多个区域来区分肺动脉和肺静脉。 量化血管的方法包括：基于器官的医学图像将血管提取为三维体素组; 找到包含在器官感兴趣区域的血管的体素; 以及通过使用发现的体素来量化血管的长度信息。
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83.发明申请MARKER COMPOSITION COMPRISING S1P PROTEIN FOR PREDICTION OF RISK IN OSTEOPOROTIC FRACTURE AND OSTEOPOROSIS 审中-公开包含S1P蛋白质的标记物组合物，用于预测OSTEOPOROTIC FRACTURE和OSTEOPOSOSIS的风险公开(公告)号：US20130331282A1
公开(公告)日：2013-12-12
申请号：US13865688
申请日：2013-04-18
Applicant: THE ASAN FOUNDATION
Inventor： Jung Min Koh , Ghi Su Kim , Seung Hun Lee , Beom Jun Kim
CPC classification number: G01N33/92 , C07K14/47 , C07K16/18 , G01N33/6893 , G01N2405/08 , G01N2800/108
Abstract: Disclosed herein is a marker composition that includes sphingosine 1-phosphate (S1P) protein and that may be used to predict the risk of fracture or osteoporosis; a kit that includes an antibody that specifically binds to the S1P protein and that can be used to predict the risk of fracture or osteoporosis; and a method that can be used to obtain information that allows prediction of the risk of fracture or osteoporosis and includes measurements of S1P protein concentrations by measuring the binding of a S1P-specific antibody to S1P protein. The S1P protein disclosed herein is highly expressed in individuals with fracture, regardless of their bone mineral density. Accordingly, it may be useful as a biomarker of the risk of fracture or osteoporosis.
Abstract translation: 本文公开了包含鞘氨醇1-磷酸（S1P）蛋白质并可用于预测骨折或骨质疏松症风险的标记物组合物; 包括特异性结合S1P蛋白并可用于预测骨折或骨质疏松症风险的抗体的试剂盒; 以及可用于获得允许预测骨折或骨质疏松症风险的信息的方法，并且包括通过测量S1P特异性抗体与S1P蛋白的结合来测量S1P蛋白浓度。 本文公开的S1P蛋白质在具有骨折的个体中高度表达，而不管其骨矿物质密度如何。 因此，作为骨折或骨质疏松症风险的生物标志物可能是有用的。
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公开(公告)号：US20250041046A1
公开(公告)日：2025-02-06
申请号：US18715840
申请日：2022-12-02
Inventor： Hun LEE , Chang Mo HWANG
Abstract: The present disclosure relates to a corneal endothelial tissue transplantation system for easily and precisely moving corneal endothelial tissue inserted into an anterior chamber of an eyeball. To this end, the corneal endothelial tissue transplantation system according to an embodiment of the present disclosure includes a tissue carrier to which cultured corneal endothelial tissue is attached and which is inserted into an anterior chamber of an eyeball, a magnetic field generation module including at least one magnetic field generator which generates a magnetic field for moving the tissue carrier, and a support plate which supports the magnetic field generator, and a user input module which receives an input signal for controlling the magnetic field generator from a user.
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公开(公告)号：US20250035632A1
公开(公告)日：2025-01-30
申请号：US18707174
申请日：2022-11-11
Applicant: INSTITUT PASTEUR KOREA , THE ASAN FOUNDATION , UNIVERSITY OF ULSAN FOUNDATION FOR INDUSTRY COOPERATION
Inventor： Kang Mo KIM , Haeng Ran SEO , Su-Yeon LEE , Jin-Sun KIM , Yeonhwa SONG , Sanghwa KIM
IPC: G01N33/574
Abstract: The present invention relates to a method, a composition, and a kit for preoperative prediction of prognosis after liver cancer surgery at an early stage by detecting, in a blood sample obtained from a liver cancer patient prior to surgery, an SORD marker, or an SORD marker together with an AFP marker.
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Patent Agency Ranking
公开(公告)号：US20250005746A1
公开(公告)日：2025-01-02
申请号：US18681973
申请日：2021-12-06
Inventor： Jihoon KWEON , Joong-Ho AHN , Yeonjoo CHOI , Keunwoo PARK , Jihye CHAE
Abstract: A tympanum image processing apparatus may comprise: a processor which extracts, from a tympanum image, a tympanum outline of the tympanum image and earwax region of the tympanum image by using a first machine learning model, obtains, on the basis of the tympanum outline of the tympanum image, a target image of the entire tympanum, a tympanum outline of the target image, and earwax region of the target image, and generates a transformed image in which an abnormal region of the target image is changed to a normal region; and a display which displays at least one of the transformed image and the target image so that a tympanum region of the transformed image is aligned at a position corresponding to the position of a tympanum region of the target image.
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公开(公告)号：US20240417474A1
公开(公告)日：2024-12-19
申请号：US18704793
申请日：2022-10-24
Inventor： Su Hwan CHANG , Jong Won LEE , Sae Byul LEE , Eun Young CHOI , Yong Sub KIM , Geon Yeong KIM , Su Min SON
Abstract: An antibody derived from a cancer survivor and use thereof. More particularly, among antibodies derived from survivors of 5 or more years from breast cancer surgery, an antibody showing high binding strength to cancer cells and having an inhibitory effect on the growth and migration of cancer cells is selected to identify an antigen of the antibody. The antibody is then highly likely to contribute to the survival of cancer patients and unlikely to cause adverse effects upon administration, and thus, can be widely used clinically for preventing and treating cancer and inhibiting metastasis.
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公开(公告)号：US20240395157A1
公开(公告)日：2024-11-28
申请号：US18757699
申请日：2024-06-28
Applicant: NUNAPS INC. , THE ASAN FOUNDATION , UNIVERSITY OF ULSAN FOUNDATION FOR INDUSTRY COOPERATION
Inventor： Dong Wha KANG , Inseok PARK , Hagyun CHOI , Yong Hoe RYU
Abstract: Disclosed are a cognitive training providing apparatus and a method thereof. The cognitive training providing apparatus includes a display module, a memory that stores health status information of a trainee, pieces of multimedia content, and a plurality of training tasks, an input module that receives a response of the trainee, and a control module that selects first multimedia content corresponding to the health status information among the pieces of multimedia content, selects a first training task corresponding to the first multimedia content among the plurality of training tasks, organizes game content by placing the first training task in the first multimedia content, and performs a cognitive training operation by outputting the game content through the display module.
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89.发明公开公开(公告)号：US20240331848A1
公开(公告)日：2024-10-03
申请号：US18621438
申请日：2024-03-29
Applicant: CORELINE SOFT CO., LTD. , The Asan Foundation , UNIV OF ULSAN FOUNDATION FOR INDUSTRY COOPERATION
Inventor： Joon Beom SEO , Sang Min LEE , Jihye YUN , Seungbin BAE , Donghoon YU , Jaeyoun YI
CPC classification number: G16H30/40 , G06T7/0012 , G06T2207/30061
Abstract: A method according to an embodiment of the present disclosure includes obtaining a first finding region in a first medical image and size information of the first finding region; identifying a second finding region matching the first finding region in a second medical image obtained after the first medical image; obtaining size information of the second finding region; and generating diagnosis assistance information based on the size information of the first finding region and the second finding region.
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公开(公告)号：US20240278037A1
公开(公告)日：2024-08-22
申请号：US18564790
申请日：2022-05-16
Inventor： Do Hoon KIM , Jung-Hoon PARK , Daesung RYU
CPC classification number: A61N5/062 , A61F2/90 , A61F2/95 , A61N5/067 , A61F2210/0076 , A61F2250/0067 , A61N2005/0643
Abstract: A catheter apparatus for photodynamic therapy includes: a catheter movable to a lesion site of tissues; a stent installed to be inserted into and retracted from an end of the catheter such that a length thereof is adjustable, and coated with a photosensitizer, and an optical fiber inserted into the catheter to be movable to be positioned at a central portion of the stent. The optical fiber irradiates the photosensitizer with a laser to activate the photosensitizer in a state where the stent is pulled out from the catheter and expanded.
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