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81.
公开(公告)号:US4636463A
公开(公告)日:1987-01-13
申请号:US597179
申请日:1984-04-05
IPC分类号: G01N33/53 , A61K39/00 , C07K7/08 , C07K14/005 , C07K14/195 , C07K14/52 , C07K14/54 , C07K14/55 , C07K16/00 , C07K16/24 , C07K17/02 , C07K17/14 , C07K19/00 , C12P21/02 , C12Q1/00 , G01N33/577 , G01N33/68 , G01N33/531 , G01N33/535
CPC分类号: G01N33/6869 , C07K14/55 , C07K16/246 , C07K2317/34 , Y10S435/81 , Y10S435/975 , Y10S436/808 , Y10S436/823 , Y10S930/141
摘要: Chemically synthesized polypeptides containing about 6 to about 40 amino acid residues having amino acid residue sequences that substantially correspond to the amino acid residue sequences of antigenic determinants of interleukin-2, when administered alone or as polymers or as conjugates bound to carriers, induce the production of antibodies of predetermined specificities. The polypeptides and the antibodies produced thereto can be used in diagnostic systems to measure the presence and amount of interleukin-2 and interleukin-2 cell surface receptors or binding sites in an assayed sample.
摘要翻译: 包含约6至约40个氨基酸残基的化学合成的多肽具有氨基酸残基序列,其基本上对应于白细胞介素-2的抗原决定簇的氨基酸残基序列,当单独施用或作为聚合物或结合至载体的缀合物时,诱导产生 的预定特异性抗体。 多肽及其产生的抗体可用于诊断系统,以测量测定样品中白介素-2和白细胞介素-2细胞表面受体或结合位点的存在和数量。
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公开(公告)号:US4544500A
公开(公告)日:1985-10-01
申请号:US682819
申请日:1984-12-18
申请人: James L. Bittle , Richard A. Lerner
发明人: James L. Bittle , Richard A. Lerner
IPC分类号: A61K39/00 , G01N33/569 , C07C103/52
CPC分类号: G01N33/56983 , A61K39/00 , Y10S530/806 , Y10S930/222
摘要: Synthetic antigens in which the principal antigenicity derives from synthetic peptide corresponding to the 130-160 region of the foot-and-mouth disease virus are described.
摘要翻译: 描述了其主要抗原性来源于对应于口蹄疫病毒的130-160区域的合成肽的合成抗原。
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