公开(公告)号：US20060211149A1

公开(公告)日：2006-09-21

申请号：US11439813

申请日：2006-05-23

申请人： George Jackowski ,  John Marshall

发明人： George Jackowski ,  John Marshall

IPC分类号： G01N33/543 ,  G01N33/00 ,  C07K16/26

CPC分类号： C07K14/78 ,  Y10T436/24 ,  Y10T436/255

摘要： The instant invention involves the use of a combination of preparatory steps in conjunction with mass spectroscopy and time-of-flight detection procedures to maximize the diversity of biopolymers which are verifiable within a particular sample. The cohort of biopolymers verified within such a sample is then viewed with reference to their ability to evidence at least one particular disease state; thereby enabling a diagnostician to gain the ability to characterize either the presence or absence of said at least one disease state relative to recognition of the presence and/or the absence of said biopolymer, predict disease risk assessment, and develop therapeutic avenues against said disease.

公开(公告)号：US20060211140A1

公开(公告)日：2006-09-21

申请号：US11437924

申请日：2006-05-19

申请人： George Jackowski ,  John Marshall

发明人： George Jackowski ,  John Marshall

IPC分类号： G01N33/543 ,  G01N33/00 ,  C07K16/26

CPC分类号： C07K14/775 ,  G01N33/6893 ,  Y10T436/24

摘要： The instant invention involves the use of a combination of preparatory steps in conjunction with mass spectroscopy and time-of-flight detection procedures to maximize the diversity of biopolymers which are verifiable within a particular sample. The cohort of biopolymers verified within such a sample is then viewed with reference to their ability to evidence at least one particular disease state; thereby enabling a diagnostician to gain the ability to characterize either the presence or absence of said at least one disease state relative to recognition of the presence and/or the absence of said biopolymer, predict disease risk assessment, and develop therapeutic avenues against said disease.

公开(公告)号：US20060211139A1

公开(公告)日：2006-09-21

申请号：US11437919

申请日：2006-05-19

申请人： George Jackowski ,  John Marshall

发明人： George Jackowski ,  John Marshall

IPC分类号： G01N33/543 ,  G01N33/00 ,  C07K16/26

CPC分类号： C07K14/775 ,  G01N33/6893 ,  Y10T436/24

摘要： The instant invention involves the use of a combination of preparatory steps in conjunction with mass spectroscopy and time-of-flight detection procedures to maximize the diversity of biopolymers which are verifiable within a particular sample. The cohort of biopolymers verified within such a sample is then viewed with reference to their ability to evidence at least one particular disease state; thereby enabling a diagnostician to gain the ability to characterize either the presence or absence of said at least one disease state relative to recognition of the presence and/or the absence of said biopolymer, predict disease risk assessment, and develop therapeutic avenues against said disease.

公开(公告)号：US20060211138A1

公开(公告)日：2006-09-21

申请号：US11437883

申请日：2006-05-19

申请人： George Jackowski ,  John Marshall

发明人： George Jackowski ,  John Marshall

IPC分类号： G01N33/543 ,  G01N33/00 ,  C07K16/26

CPC分类号： C07K14/775 ,  G01N33/6893 ,  Y10T436/24

摘要： The instant invention involves the use of a combination of preparatory steps in conjunction with mass spectroscopy and time-of-flight detection procedures to maximize the diversity of biopolymers which are verifiable within a particular sample. The cohort of biopolymers verified within such a sample is then viewed with reference to their ability to evidence at least one particular disease state; thereby enabling a diagnostician to gain the ability to characterize either the presence or absence of said at least one disease state relative to recognition of the presence and/or the absence of said biopolymer, predict disease risk assessment, and develop therapeutic avenues against said disease.

公开(公告)号：US20060194340A1

公开(公告)日：2006-08-31

申请号：US09993393

申请日：2001-11-23

申请人： George Jackowski ,  John Marshall

发明人： George Jackowski ,  John Marshall

IPC分类号： G01N33/00 ,  G01N33/543 ,  C07K14/47

CPC分类号： C07K14/47 ,  Y10T436/24 ,  Y10T436/255

摘要： The instant invention involves the use of a combination of preparatory steps in conjunction with mass spectroscopy and time-of-flight detection procedures to maximize the diversity of biopolymers which are verifiable within a particular sample. The cohort of biopolymers verified within such a sample is then viewed with reference to their ability to evidence at least one particular disease state; thereby enabling a diagnostician to gain the ability-to characterize either the presence or absence of said at least one disease state relative to recognition of the presence and/or the absence of said biopolymer, predict disease risk assessment, and develop therapeutic avenues against said disease.

摘要翻译： 本发明涉及使用组合的准备步骤与质谱法和飞行时间检测程序的组合，以使特定样品中可验证的生物聚合物的多样性最大化。 然后，在这样一个样本中验证的生物聚合物队列参照其证明至少一种特定疾病状态的能力; 从而使得诊断者能够获得表征所述至少一种疾病状态的存在或不存在的能力，以相对于所述生物聚合物的存在和/或不存在的识别，预测疾病风险评估以及开发针对所述疾病的治疗途径 。

公开(公告)号：US20060194337A1

公开(公告)日：2006-08-31

申请号：US09993289

申请日：2001-11-23

申请人： George Jackowski ,  John Marshall

发明人： George Jackowski ,  John Marshall

IPC分类号： G01N33/543 ,  C07K14/47

CPC分类号： C07K14/78 ,  G01N33/6896 ,  G01N2500/00 ,  G01N2800/2821 ,  Y10S435/81

摘要： The instant invention involves the use of a combination of preparatory steps in conjunction with mass spectroscopy and time-of-flight detection procedures to maximize the diversity of biopolymers which are verifiable within a particular sample. The cohort of biopolymers verified within such a sample is then viewed with reference to their ability to evidence at least one particular disease state; thereby enabling a diagnostician to gain the ability to characterize either the presence or absence of said at least one disease state relative to recognition of the presence and/or the absence of said biopolymer, predict disease risk assessment, and develop therapeutic avenues against said disease.

摘要翻译： 本发明涉及使用组合的准备步骤与质谱法和飞行时间检测程序的组合，以使特定样品中可验证的生物聚合物的多样性最大化。 然后，在这样一个样本中验证的生物聚合物队列参照其证明至少一种特定疾病状态的能力; 从而使得诊断者能够获得表征所述至少一种疾病状态的存在或不存在的能力，以相对于识别所述生物聚合物的存在和/或不存在，预测疾病风险评估以及开发针对所述疾病的治疗途径。

公开(公告)号：US20060160233A1

公开(公告)日：2006-07-20

申请号：US09993304

申请日：2001-11-23

申请人： George Jackowski ,  John Marshall

发明人： George Jackowski ,  John Marshall

IPC分类号： G01N33/00 ,  C07K14/47

CPC分类号： C07K16/00 ,  C07K2317/50 ,  G01N33/6857 ,  G01N33/6896 ,  G01N2500/00 ,  G01N2800/2821 ,  Y10T436/24 ,  Y10T436/255

摘要： The instant invention involves the use of a combination of preparatory steps in conjunction with mass spectroscopy and time-of-flight detection procedures to maximize the diversity of biopolymers which are verifiable within a particular sample. The cohort of biopolymers verified within such a sample is then viewed with reference to their ability to evidence at least one particular disease state; thereby enabling a diagnostician to gain the ability to characterize either the presence or absence of said at least one disease state relative to recognition of the presence and/or the absence of said biopolymer, predict disease risk assessment, and develop therapeutic avenues against said disease.

摘要翻译： 本发明涉及使用组合的准备步骤与质谱法和飞行时间检测程序的组合，以使特定样品中可验证的生物聚合物的多样性最大化。 然后，在这样一个样本中验证的生物聚合物队列参照其证明至少一种特定疾病状态的能力; 从而使得诊断者能够获得表征所述至少一种疾病状态的存在或不存在的能力，以相对于识别所述生物聚合物的存在和/或不存在，预测疾病风险评估以及开发针对所述疾病的治疗途径。

公开(公告)号：US20060147095A1

公开(公告)日：2006-07-06

申请号：US11028726

申请日：2005-01-03

申请人： David Usher ,  Gregory Heacock ,  John Marshall ,  David Mueller

发明人： David Usher ,  Gregory Heacock ,  John Marshall ,  David Mueller

IPC分类号： G06K9/00

CPC分类号： G06K9/00604

摘要： A method and system capture an image of the interior of the eye, for example the retina and determine whether the captured image is sufficient to provide data for identifying an individual or animal before attempting to generate the identification data. If the captured image is not sufficient, the method and system automatically capture another image of the interior of the eye.

摘要翻译： 一种方法和系统捕获眼睛内部的图像，例如视网膜，并且在尝试产生识别数据之前，确定捕获的图像是否足以提供用于识别个体或动物的数据。 如果拍摄的图像不足，则该方法和系统自动捕获眼睛内部的另一图像。

公开(公告)号：US07052849B2

公开(公告)日：2006-05-30

申请号：US09991627

申请日：2001-11-23

申请人： George Jackowski ,  John Marshall

发明人： George Jackowski ,  John Marshall

IPC分类号： G01N33/53

CPC分类号： C07K14/775 ,  G01N33/6893 ,  Y10T436/24

摘要： The instant invention involves the use of a combination of preparatory steps in conjunction with mass spectroscopy and time-of-flight detection procedures to maximize the diversity of biopolymers which are verifiable within a particular sample. The cohort of biopolymers verified within such a sample is then viewed with reference to their ability to evidence at least one particular disease state; thereby enabling a diagnostician to gain the ability to characterize either the presence or absence of at least one disease state relative to recognition of the presence and/or the absence of the biopolymer, predict disease risk assessment, and develop therapeutic avenues against the disease.

摘要翻译： 本发明涉及使用组合的准备步骤与质谱法和飞行时间检测程序的组合，以使特定样品中可验证的生物聚合物的多样性最大化。 然后，在这样一个样本中验证的生物聚合物队列参照其证明至少一种特定疾病状态的能力; 从而使得诊断者能够获得表征与识别生物聚合物的存在和/或不存在相关的至少一种疾病状态的存在或不存在的能力，预测疾病风险评估以及开发针对该疾病的治疗途径。

公开(公告)号：US20060084951A1

公开(公告)日：2006-04-20

申请号：US11240403

申请日：2005-09-30

申请人： Gregory Heacock ,  John Marshall ,  Paula Mahoney

发明人： Gregory Heacock ,  John Marshall ,  Paula Mahoney

IPC分类号： A61B18/18

CPC分类号： A61F9/0079 ,  A61F9/009 ,  A61F2009/00863 ,  A61F2009/00891 ,  A61N5/062

摘要： A photodynamic therapy includes a particular combination of a photosensitizer and light source for a photodynamic therapy used to treat ocular diseases. The photosensitizer has a peak excitation level when exposed to light of a given wavelength where the wavelength of light is absorbed at a particular location of the eye to be treated. The light source has a wavelength within the excitation range of the photosensitizer and matched to the location of the diseased eye tissue. The light source also has an irradiance level and energy level that is effective for therapy but at levels below the maximum permissible exposure level.

摘要翻译： 光动力疗法包括用于治疗眼部疾病的光动力疗法的光敏剂和光源的特定组合。 当光敏剂暴露于给定波长的光，其中光的波长被吸收在待治疗的眼睛的特定位置时，光敏剂具有峰值激发水平。 光源具有在光敏剂的激发范围内的波长，并与病眼组织的位置相匹配。 光源还具有对治疗有效的辐照度水平和能量水平，但水平低于最大允许暴露水平。