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    Methods of implanting a cardiac implant with integrated suture fasteners
    82.
    发明授权
    Methods of implanting a cardiac implant with integrated suture fasteners 有权

    公开(公告)号：US10314706B2

    公开(公告)日：2019-06-11

    申请号：US15625801

    申请日：2017-06-16

    Applicant: Edwards Lifesciences Corporation

    Inventor： Salvador Marquez ,  Brian S. Conklin ,  Manouchehr A. Miraki ,  Yoon H. Kwon

    IPC: A61F2/24 ,  A61B17/04 ,  A61B17/02

    Abstract: A cardiac implant system including a cardiac implant such as an annuloplasty ring, a prosthetic heart valve, or a valved conduit pre-assembled at the time of manufacture with devices for securing the implant to a heart valve annulus using knotless suture fasteners. The knotless suture fasteners may be embedded within a pliant sealing edge of the cardiac implant, or they may be positioned adjacent to the sealing edge. The knotless suture fasteners are spring-biased so as to grip onto annulus anchoring sutures pass to therethrough upon removal of a restraining device, such as a hypotube inserted within the suture fasteners. Guide tubes are assembled in line with the suture fasteners to permit introduction of suture snares that pass through the suture fasteners and through the sealing edge to facilitate capture of the pre-installed annulus anchoring sutures.

    Limited expansion heart valve
    83.
    发明授权
    Limited expansion heart valve 有权

    公开(公告)号：US10080653B2

    公开(公告)日：2018-09-25

    申请号：US15260053

    申请日：2016-09-08

    Applicant: Edwards Lifesciences Corporation

    Inventor： Brian S. Conklin ,  Da-Yu Chang

    IPC: A61F2/24

    CPC classification number: A61F2/2418 ,  A61F2/2409 ,  A61F2220/0033 ,  A61F2220/0075

    Abstract: A prosthetic heart valve configured to replace a native heart valve and having a support frame configured to be reshaped into an expanded form in order to receive and/or support an expandable prosthetic heart valve therein is disclosed, together with methods of using same. Interlocking members or flexible loops are included to limit expansion of the valve to one or two valve sizes, for example, with a 2-mm gap between each valve size. The valve may include an internal structural band with overlapped free ends having structure for limiting expansion, or external loops of suture may be added to the fabric covering which limits expansion.

    PROSTHETIC MITRAL VALVE HOLDERS
    85.
    发明申请
    PROSTHETIC MITRAL VALVE HOLDERS 审中-公开

    公开(公告)号：US20180116795A1

    公开(公告)日：2018-05-03

    申请号：US15796147

    申请日：2017-10-27

    Applicant: Edwards Lifesciences Corporation

    Inventor： Brian S. Conklin ,  Derrick Johnson

    IPC: A61F2/24 ,  A61B17/00

    Abstract: Valve holders and introducers for delivering a prosthetic heart valve to an implant site are in various embodiments configured to facilitate insertion of prosthetic valves through small incisions or access sites on a patient's body. The valve holders can also be configured to reduce or eliminate the occurrence of suture looping or other damage to the prosthetic valve during implantation. A valve holder according to embodiments of the invention includes features that reduce or eliminate mistakes during implantation of the prosthetic valves, such as a removable activator dial and a removable handle that prevent implantation of the valve prior to proper deployment or adjustment of the holder. An introducer is provided which can facilitate passing of a prosthetic valve between adjacent ribs of a patient. Valve holders and introducers according to the various embodiments can be used in minimally invasive procedures, such as thoracotomy procedures.

    CARDIAC IMPLANT WITH INTEGRATED SUTURE FASTENERS
    89.
    发明申请
    CARDIAC IMPLANT WITH INTEGRATED SUTURE FASTENERS 有权
    CARDIAC植入与集成紧固件

    公开(公告)号：US20170027695A1

    公开(公告)日：2017-02-02

    申请号：US15295912

    申请日：2016-10-17

    Applicant: Edwards Lifesciences Corporation

    Inventor： Salvador Marquez ,  Brian S. Conklin ,  Manouchehr A. Miraki ,  Yoon H. Kwon

    IPC: A61F2/24 ,  A61B17/02 ,  A61B17/04

    CPC classification number: A61F2/2445 ,  A61B17/02 ,  A61B17/0487 ,  A61B2017/0237 ,  A61B2017/0488 ,  A61F2/2409 ,  A61F2/2412 ,  A61F2/2448

    Abstract: A cardiac implant system including a cardiac implant such as an annuloplasty ring, a prosthetic heart valve, or a valved conduit pre-assembled at the time of manufacture with devices for securing the implant to a heart valve annulus using knotless suture fasteners. The knotless suture fasteners may be embedded within a pliant sealing edge of the cardiac implant, or they may be positioned adjacent to the sealing edge. The knotless suture fasteners are spring-biased so as to grip onto annulus anchoring sutures pass to therethrough upon removal of a restraining device, such as a hypotube inserted within the suture fasteners. Guide tubes are assembled in line with the suture fasteners to permit introduction of suture snares that pass through the suture fasteners and through the sealing edge to facilitate capture of the pre-installed annulus anchoring sutures.

    Abstract translation: 一种心脏植入系统，其包括心脏植入物，例如瓣膜成形术环，假体心脏瓣膜或在制造时预先组装的带阀的导管，其中装置使用无缝缝合紧固件将植入物固定到心脏瓣膜环。 无缝缝合紧固件可以嵌入在心脏植入物的柔性密封边缘内，或者它们可以邻近密封边缘定位。 无缝缝合紧固件被弹簧偏置，以便在去除限制装置（例如插入缝合线紧固件内的海波管）时夹紧到环形锚固缝合线上。 引导管与缝合线紧固件一起组装，以允许引入通过缝合线紧固件并穿过密封边缘的缝合线圈，以便于捕获预先安装的环形锚定缝合线。

    Methods of deploying knotless suture anchoring clamps
    90.
    发明授权
    Methods of deploying knotless suture anchoring clamps 有权
    无缝缝合锚固夹具的部署方法

    公开(公告)号：US09504466B2

    公开(公告)日：2016-11-29

    申请号：US14797112

    申请日：2015-07-11

    Applicant: Edwards Lifesciences Corporation

    Inventor： Brian S. Conklin ,  Louis A. Campbell ,  Salvador Marquez ,  Donald E. Bobo, Jr.

    IPC: A61B17/04 ,  A61F2/24

    CPC classification number: A61B17/0487 ,  A61B17/0401 ,  A61B2017/0404 ,  A61B2017/0409 ,  A61B2017/0414 ,  A61B2017/0416 ,  A61B2017/0464 ,  A61B2017/0488 ,  A61B2017/0496 ,  A61F2/24 ,  A61F2/2409 ,  A61F2/2442

    Abstract: Methods of deploying knotless suture locking clamps for securing prostheses such as heart valves or annuloplasty rings to facilitate implantation. The clamps have opposed clamp halves separated by a slot opening to one side and surrounded by a biasing member such as one or more C-clip springs. Sutures pass laterally into the slot which is held open by a retention member positioned between the clamp halves. The locking clamp slides along the sutures into position, the tension of the sutures is adjusted, and the retention member removed to allow the biasing member to clamp the sutures between the clamp halves. A delivery tool used to deliver and deploy the locking clamps contains a number of clamps within a delivery tube in a stack and bonded together for safety and a common retention member. The tool has a longitudinal channel on one side for entry of sutures.

    Abstract translation: 部署用于固定假体（例如心脏瓣膜或瓣环成形术环）的无缝缝合锁定夹具的方法以便于植入。 夹具具有相对的夹具半部，该半部由通向一侧的狭槽分开，并被诸如一个或多个C形夹弹簧的偏置构件包围。 缝合线横向穿过狭槽，狭槽由位于夹子半部之间的保持构件保持打开。 锁定夹具沿着缝合线滑动到适当位置，调节缝合线的张力，并且移除保持构件以允许偏置构件将缝合线夹在夹具半部之间。 用于传送和展开锁定夹具的输送工具在堆叠中的输送管内包含多个夹具，并且为了安全而将其粘合在一起并具有公共保持构件。 该工具在一侧具有用于进入缝合线的纵向通道。

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