公开(公告)号：US06716661B2

公开(公告)日：2004-04-06

申请号：US10147006

申请日：2002-05-16

申请人： Quanbo Zou ,  Yu Chen ,  Janak Singh ,  Tit Meng Lim ,  Tie Yan ,  Chew Kiat Heng

发明人： Quanbo Zou ,  Yu Chen ,  Janak Singh ,  Tit Meng Lim ,  Tie Yan ,  Chew Kiat Heng

IPC分类号： H01L2100

CPC分类号： B81C1/00214 ,  B81C2201/0132 ,  F04B43/043

摘要： Formation of micro-fluidic systems is normally achieved using a multi-wafer fabrication procedure. The present invention teaches how a complete micro-fluidic system can be implemented on a single chip. The invention uses only dry etch processes to form micro-chambers. In particular, it makes use of deep reactive ion etching whereby multiple trenches of differing depths may be formed simultaneously. Buried micro-chambers are formed by isotropically increasing trench widths using an etchant that does not attack the mask so the trenches grow wider beneath the surface until they merge. Deposition of a dielectric layer over the trenches allows some trenches to be sealed and some to be left open. Micro-pumps are formed by including in the micro-chamber roof a layer that is used to change chamber volume either through electrostatically induced motion or through thermal mismatch as a result of its being heated.

摘要翻译： 微流体系统的形成通常使用多晶片制造程序来实现。 本发明教导了如何在单个芯片上实现完整的微流体系统。 本发明仅使用干蚀刻工艺来形成微室。 特别地，它利用深反应离子蚀刻，从而可以同时形成不同深度的多个沟槽。 通过使用不侵蚀掩模的蚀刻剂各向同性地增加沟槽宽度来形成掩埋的微室，使得沟槽在表面下方变得更宽，直到它们合并。 电介质层沉积在沟槽上方允许一些沟槽被密封，有些则被打开。 通过在微室顶中包含用于通过静电诱导运动或通过其被加热的结果的热失配来改变室容积的层而形成微泵。

公开(公告)号：US06521447B2

公开(公告)日：2003-02-18

申请号：US10188641

申请日：2002-07-03

申请人： Quanbo Zou ,  Uppili Sridhar ,  Yu Chen ,  Tit Meng Lim ,  Emmanuel Selvanayagam Zachariah ,  Tie Yan

发明人： Quanbo Zou ,  Uppili Sridhar ,  Yu Chen ,  Tit Meng Lim ,  Emmanuel Selvanayagam Zachariah ,  Tie Yan

IPC分类号： C12M134

CPC分类号： B01L3/5027 ,  B01L3/5025 ,  B01L7/52 ,  B01L2200/147 ,  B01L2300/0816 ,  B01L2300/0877 ,  B01L2300/1827 ,  B01L2300/1883 ,  B01L2400/0487 ,  B01L2400/0688

摘要： The invention describes a thermal cycler which permits simultaneous treatment of multiple individual samples in independent thermal protocols, so as to implement large numbers of DNA experiments simultaneously in a short time. The chamber is thermally isolated from its surroundings, heat flow in and out of the unit being limited to one or two specific heat transfer areas. All heating elements are located within these transfer areas and at least one temperature sensor per heating element is positioned close by. Fluid bearing channels that facilitate sending fluid into, and removing fluid from, the chamber are provided. The chambers may be manufactured as integrated arrays to form units in which each cycler chamber has independent temperature and fluid flow control. Two embodiments of the invention are described together with a process for manufacturing them.

公开(公告)号：US06406861B1

公开(公告)日：2002-06-18

申请号：US09413044

申请日：1999-10-06

申请人： Daniel R. Henderson ,  Yu Chen ,  De Chao Yu

发明人： Daniel R. Henderson ,  Yu Chen ,  De Chao Yu

IPC分类号： G01N3353

CPC分类号： A61K48/00 ,  A61M1/3679 ,  Y10S514/885

摘要： Methods of reducing pre-existing humoral immunity to a viral immunogenic therapeutic agent such as adenovirus, using immunoapheresis are disclosed. Antibodies specific for the viral immunogenic therapeutic agent are selectively removed from the blood of an individual prior to administration of the viral immunogenic therapeutic agent by reaction extracorporeally with an immunosorbent which specifically binds the antibody. After the antibody is selectively removed from the blood, the blood is reinfused into the patient and the viral immunogenic therapeutic agent is administered. The invention also provides kits and compositions for selective removal of anti-viral antibody.

摘要翻译： 公开了使用免疫分离法减少病毒免疫原性治疗剂如腺病毒的预先存在的体液免疫的方法。 在给予病毒免疫原性治疗剂之前，通过与特异性结合抗体的免疫吸附剂体外反应，选择性地从个体的血液中除去病毒免疫原性治疗剂的特异性抗体。 在从血液中选择性地除去抗体后，将血液再次输注到患者体内，并施用病毒免疫原性治疗剂。 本发明还提供用于选择性除去抗病毒抗体的试剂盒和组合物。

公开(公告)号：US6090389A

公开(公告)日：2000-07-18

申请号：US177973

申请日：1998-10-26

申请人： Yu Chen

发明人： Yu Chen

IPC分类号： A61K9/00 ,  A61K36/515 ,  A61K36/539 ,  A61K35/78 ,  A61K9/20 ,  A61K9/48

CPC分类号： A61K36/515 ,  A61K9/0034 ,  Y10S514/937 ,  Y10S514/944 ,  Y10S514/945 ,  Y10S514/962 ,  Y10S514/967

摘要： A method and preparations for the treatment of vaginal yeast and other yeast infections is provided for the treatment of infections caused by Candida albicans and Cryptococcus neoformans. The method and preparations of the invention can also be used for other yeast and fungal infections including systemic, mucosal and cutaneous caused by Candida and Cryptococcus. The vaginal antiyeast and antifungal preparations include, in addition to suppositories and mouth washes, troches, lotions, creams, tablets and capsules containing gentian preparations as an active ingredient obtained from the plant Radix gentianae Longdancao. For systemic fungal infections gentian preparations from the plant Radix gentianae Longdancao are taken orally in the form of lozenges, tablets, capsules or in solution form for gargling or swallowing.

摘要翻译： 提供了用于治疗阴道酵母和其他酵母菌感染的方法和制剂，用于治疗由白色念珠菌和新型隐球蛋白引起的感染。 本发明的方法和制剂也可用于其它酵母和真菌感染，包括由念珠菌和隐球菌引起的全身，粘膜和皮肤。 除了栓剂和漱口剂之外，阴道抗菌和抗真菌制剂还包括从植物龙胆龙胆制得的龙胆制剂作为活性成分的锭剂，洗剂，霜剂，片剂和胶囊剂。 对于系统性真菌感染，来自植物龙胆龙胆的龙胆制剂以锭剂，片剂，胶囊或溶液形式口服口服用于漱口或吞咽。

公开(公告)号：USD996411S1

公开(公告)日：2023-08-22

申请号：US29892568

申请日：2023-05-19

申请人： Yu Chen

设计人： Yu Chen

摘要： FIG. 1 is a front, right and top perspective view of a case for mobile telephone, showing my design.
FIG. 2 is a rear, left and bottom perspective view thereof.
FIG. 3 is a front elevation view thereof.
FIG. 4 is a rear elevation view thereof.
FIG. 5 is a left side elevation view thereof.
FIG. 6 is a right side elevation view thereof.
FIG. 7 is a top plan view thereof; and,
FIG. 8 is a bottom plan view thereof.

公开(公告)号：USD996410S1

公开(公告)日：2023-08-22

申请号：US29892567

申请日：2023-05-19

申请人： Yu Chen

设计人： Yu Chen

摘要： FIG. 1 is a front, right and top perspective view of a case for mobile telephone, showing my design.
FIG. 2 is a rear, left and bottom perspective view thereof.
FIG. 3 is a front elevation view thereof.
FIG. 4 is a rear elevation view thereof.
FIG. 5 is a left side elevation view thereof.
FIG. 6 is a right side elevation view thereof.
FIG. 7 is a top plan view thereof; and,
FIG. 8 is a bottom plan view thereof.
The broken lines depict portions of the case for mobile telephone that form no part of the claimed design.

公开(公告)号：US20220100887A1

公开(公告)日：2022-03-31

申请号：US17143182

申请日：2021-01-07

申请人： Xiang Wu ,  Huanhuan Wang ,  Lian Liu ,  Ruirui Li ,  Yu Chen ,  Jingyuan Wang

发明人： Xiang Wu ,  Huanhuan Wang ,  Lian Liu ,  Ruirui Li ,  Yu Chen ,  Jingyuan Wang

IPC分类号： G06F21/62 ,  G06F16/2455

摘要： The invention discloses privacy protection query language PQL and system thereof, comprising PQL statement and system, the system comprises parsing module, query module and noise-injection module; the parsing module comprises lexical analyzer and syntactic analyzer; user inputs PQL statement according to predetermined semantic and syntactic rules, after parsing module receives the PQL statement, lexical analyzer performs error checks on the PQL statement, correct results are sent to syntactic analyzer; the syntactic analyzer performs grammatical and semantic checks on PQL statement, generates a mapping table and a parameter table with correct results; after receiving mapping table, the query module encapsulates the same into SQL statement, and verifies the encapsulated SQL statement; the noise-injection module obtains final query results of the query module, calculates noise injection sensitivity according to parameter table; the invention ensures the data privacy security and satisfies that the injected noise does not affect data availability.

公开(公告)号：US20190167116A1

公开(公告)日：2019-06-06

申请号：US16192229

申请日：2018-11-15

申请人： Yu Chen ,  Qinggong Tang ,  Udayakumar Kanniyappan ,  Lin Z. Li ,  He Xu ,  Yi Liu ,  Emily Conant

发明人： Yu Chen ,  Qinggong Tang ,  Udayakumar Kanniyappan ,  Lin Z. Li ,  He Xu ,  Yi Liu ,  Emily Conant

IPC分类号： A61B5/00 ,  A61B1/07 ,  A61B1/04 ,  A61B1/06 ,  A61B1/00 ,  A61B10/02

摘要： In accordance with aspects of the present disclosure, an exemplary system includes a hollow probe having a lumen containing one or more excitation optical fiber(s) and one or more imaging optical fiber(s) where the probe is sized to access a person's body, a first light source optically coupled to the excitation fiber(s) and configured to emit light that excites fluorescence of NADH in breast tissue, a second light source optically coupled to the excitation fiber(s) and configured to emit light that excites fluorescence of FAD in tissue such as breast tissue, an image capturing device optically coupled to the imaging fiber(s), and a controller configured to control the first light source and the image capturing device to capture NADH fluorescence signals/intensities while the probe is within the person's body and control the second light source and the image capturing device to capture FAD fluorescence signals/intensities while the probe is within the person's body.

公开(公告)号：US09949066B2

公开(公告)日：2018-04-17

申请号：US13576069

申请日：2010-02-04

申请人： Hongfei Du ,  Yu Chen

发明人： Hongfei Du ,  Yu Chen

IPC分类号： H04W4/02 ,  H04L29/08 ,  H04W4/00

CPC分类号： H04W4/02 ,  H04L67/1021 ,  H04W4/021 ,  H04W4/70

摘要： The invention provides a solution to accessing for a geographical location information-based service in a server of a machine type communication based communication system, where firstly a server broadcasts or multicasts a content request message, the content request message comprising information on requested content and information on a target geographical location; then the server receives a response message from at least one user equipment, the response message indicating that the at least one user equipment possesses the requested content and the at least one user equipment being located within the target geographical location; and finally the server acquires the requested content from the at least one user equipment.

公开(公告)号：US20170028307A1

公开(公告)日：2017-02-02

申请号：US15224148

申请日：2016-07-29

申请人： Yu Chen ,  Miu Wong

发明人： Yu Chen ,  Miu Wong

IPC分类号： A63H27/10

CPC分类号： A63H27/10 ,  A63H2027/1058 ,  A63H2027/1091

摘要： A safety feature for an LED Balloon, wherein the LED balloon comprises an LED light source secured to a housing inside the balloon, and the housing engages a locking element on the exterior of the balloon. The safety feature comprising a flexible sheet adhered to the exterior of the balloon adjacent said locking element.

摘要翻译： 一种用于LED气球的安全特征，其中所述LED球囊包括固定到所述气囊内的壳体的LED光源，并且所述壳体与所述气球的外部上的锁定元件接合。 该安全特征包括粘附在邻近所述锁定元件的球囊外部的柔性片。