公开(公告)号：US20050089897A1

公开(公告)日：2005-04-28

申请号：US10924786

申请日：2004-08-25

申请人： Chunhua Yan ,  Ming-Hui Wei ,  Karen Ketchum ,  Gennady Merkulov ,  Ellen Beasley

发明人： Chunhua Yan ,  Ming-Hui Wei ,  Karen Ketchum ,  Gennady Merkulov ,  Ellen Beasley

IPC分类号： A01K67/027 ,  A61K38/00 ,  A61K45/00 ,  A61P9/10 ,  A61P17/06 ,  A61P29/00 ,  A61P35/00 ,  C07K16/40 ,  C12N1/15 ,  C12N1/19 ,  C12N1/21 ,  C12N5/10 ,  C12N9/12 ,  C12N15/09 ,  C12N15/54 ,  C12Q1/02 ,  C12Q1/48 ,  C12Q1/68 ,  C07H21/04

CPC分类号： C12N9/1205 ,  A01K2217/05 ,  A61K38/00

摘要： The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the kinase peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the kinase peptides, and methods of identifying modulators of the kinase peptides.

公开(公告)号：US20050164291A1

公开(公告)日：2005-07-28

申请号：US11084749

申请日：2005-03-21

申请人： Zhenya Li ,  Ming-Hui Wei ,  Karen Ketchum ,  Ellen Beasley

发明人： Zhenya Li ,  Ming-Hui Wei ,  Karen Ketchum ,  Ellen Beasley

IPC分类号： A01K67/027 ,  A61K45/00 ,  A61P43/00 ,  C07K14/705 ,  C07K16/40 ,  C12M1/00 ,  C12N1/15 ,  C12N1/19 ,  C12N1/21 ,  C12N5/10 ,  C12N9/16 ,  C12N15/09 ,  C12N15/55 ,  C12Q1/02 ,  C12Q1/68 ,  G01N33/53 ,  G01N33/566 ,  C07H21/04

CPC分类号： C07K14/705

摘要： The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the transporter peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the transporter peptides, and methods of identifying modulators of the transporter peptides.

公开(公告)号：US06441156B1

公开(公告)日：2002-08-27

申请号：US09470443

申请日：1999-12-22

申请人： Michael Isaac Lerman ,  Farida Latif ,  Ming-Hui Wei ,  Fuh-Mei Duh ,  John Dorrance Minna ,  Yoshitaka Sekido ,  Boning Gao

发明人： Michael Isaac Lerman ,  Farida Latif ,  Ming-Hui Wei ,  Fuh-Mei Duh ,  John Dorrance Minna ,  Yoshitaka Sekido ,  Boning Gao

IPC分类号： C07H2102

CPC分类号： C07K14/705 ,  A61K38/00

摘要： The present invention relates to calcium channel compositions and methods of making and using same. In particular, the invention relates to calcium channel alpha2delta (&agr;2&dgr;) subunits and nucleic acid sequences encoding them. These compositions are useful in methods for identifying compounds that modulate the activity of calcium channels and for identifying compounds as therapeutic for disease.

摘要翻译： 本发明涉及钙通道组合物及其制备和使用方法。 特别地，本发明涉及钙通道α2δ（α2delta）亚基和编码它们的核酸序列。 这些组合物可用于鉴定调节钙通道活性并鉴定化合物作为疾病治疗的化合物的方法。