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公开(公告)号：US20130096669A1
公开(公告)日：2013-04-18
申请号：US13271513
申请日：2011-10-12
CPC分类号： C22C27/04 , A61F2/91 , A61F2/915 , A61L31/022 , C22C19/07 , C22C27/02 , C22C38/18 , C22F1/18
摘要： A stent and method for manufacturing a stent that achieves both strength as well as ductility. In the manufacturing process, the material used to form the stent is only partially annealed to lower the grain size across the thickness of the stent. The material is partially annealed either prior to or after the cutting a stent pattern into a tube.
摘要翻译： 用于制造实现强度和延展性的支架的支架和方法。 在制造过程中，用于形成支架的材料仅部分退火，以降低穿过支架厚度的晶粒尺寸。 在将支架图案切割成管之前或之后，该材料部分退火。
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82.发明申请HEAT TREATING APPARATUSES HAVING A MAGNETIC DRIVE SYSTEM AND RELATED METHODS 审中-公开具有磁力驱动系统的热处理装置及相关方法公开(公告)号：US20130092299A1
公开(公告)日：2013-04-18
申请号：US13271917
申请日：2011-10-12
申请人： Rainer Bregulla , Randolf Von Oepen
发明人： Rainer Bregulla , Randolf Von Oepen
摘要： Embodiments of methods for vacuum heat treating refractory metal articles (e.g., implantable medical devices), and heat treating apparatuses for use in such methods are disclosed. Heat treating refractory metal articles under high vacuum (e.g., 10−6 Torr) may improve strength and ductility and remove material contaminants (e.g., oxygen or hydrogen) that may be absorbed during manufacturing processes. Heat treating methods include disposing a refractory metal article in a heat treating apparatus, drawing a vacuum therein, and moving the article to a heated zone in the furnace using a drive system that permits movement of the article while the vacuum is maintained in the apparatus. A heat treating apparatus may include an elongate furnace tube that may be sealed and placed under vacuum, a heating element disposed around at least a portion of the tube, and a drive system configured for moving articles disposed inside the furnace tube while under vacuum.
摘要翻译： 公开了用于真空热处理难熔金属制品（例如，可植入医疗装置）的方法的实施例和用于这种方法的热处理装置。 在高真空（例如，10 -6乇）下热处理难熔金属制品可以提高强度和延展性，并去除可能在制造过程中被吸收的材料污染物（例如氧气或氢气）。 热处理方法包括将难熔金属制品放置在热处理装置中，在其中抽吸真空，并使用驱动系统将制品移动到炉中的加热区域，该驱动系统允许制品在设备内保持真空的同时运动。 热处理装置可以包括可以密封并放置在真空下的细长的炉管，设置在管的至少一部分周围的加热元件，以及构造成用于在真空下移动设置在炉管内部的物品的驱动系统。
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公开(公告)号：US08303645B2
公开(公告)日：2012-11-06
申请号：US12875971
申请日：2010-09-03
申请人： Randolf Von Oepen , Gerd Seibold
发明人： Randolf Von Oepen , Gerd Seibold
CPC分类号： A61F2/91 , A61F2/915 , A61F2002/91508 , A61F2002/91533 , A61F2002/91558
摘要： The present invention provides a stent comprising a tubular flexible body having a wall with a web structure that is expandable from a contracted delivery configuration to deployed configuration. The web structure comprises a plurality of neighboring web patterns, where each web patterns is composed of adjoining webs, and the web patterns are interconnected. Each adjoining web comprises a central section interposed between two lateral sections to form concave or convex configurations.
摘要翻译： 本发明提供了一种支架，其包括管状柔性体，其具有壁，所述壁具有可从收缩输送构型扩展到展开构造的腹板结构。 网状结构包括多个相邻的网状图案，其中每个网状图案由邻接的网构成，并且网状图案互连。 每个邻接的腹板包括插入在两个横向部分之间以形成凹形或凸形构造的中心部分。
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公开(公告)号：US20120259400A1
公开(公告)日：2012-10-11
申请号：US13350529
申请日：2012-01-13
CPC分类号： A61F2/86 , A61F2/966 , A61F2002/9505 , A61F2002/9665 , A61F2210/0076 , A61F2220/0016 , A61F2220/0041 , A61F2220/005 , A61F2220/0058 , A61F2230/005 , A61F2230/0058 , A61F2230/0076 , A61F2230/0093
摘要： Expandable intraluminal scaffold defining a longitudinal axis is provided, wherein the scaffold includes at least two filaments extending from a head portion disposed along the longitudinal axis at a first longitudinal end, each of the at least two filaments including a free end portion at a second longitudinal end opposite the head portion. The at least two filaments converge toward each other at a juncture disposed proximate the longitudinal axis between the first longitudinal end and the second longitudinal end. A system including a delivery system and the intraluminal scaffold, as well as a method of delivering the scaffold, is also provided.
摘要翻译： 提供了限定纵向轴线的可展开的管腔内支架，其中所述支架包括至少两根从沿所述纵向轴线设置的头部部分延伸的细丝，所述头部沿第一纵向端部延伸，所述至少两根细丝中的每一个包括在第二纵向 在头部相对的端部。 所述至少两根细丝在第一纵向端和第二纵向端之间的纵向轴线附近的接合部处朝向彼此会聚。 还提供了包括递送系统和管腔内支架的系统以及递送支架的方法。
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85.发明授权公开(公告)号：US08261420B2
公开(公告)日：2012-09-11
申请号：US12119945
申请日：2008-05-13
CPC分类号： A61F2/91 , A61F2210/0014 , A61F2230/0013 , A61F2230/0054 , A61F2240/001 , Y10T29/49863 , Y10T29/49865 , Y10T29/53657 , Y10T29/53909 , Y10T29/53987 , Y10T29/53996 , Y10T29/54
摘要： The invention relates to a method and apparatus of reducing stress during stent manufacture. Particularly, the invention is directed to a method and apparatus for expanding a stent using primarily radial loads thereby reducing the stresses that are generated due to the axial loads applied during loading of the stent onto a mandrel or other expansion device. The method of the invention provides for the stepwise expansion of shape memory stents, while reducing the overall stresses that the stent encounters, and thereby improving manufacturing yields due to fractured struts during expansion.
摘要翻译： 本发明涉及减少支架制造过程中的压力的方法和装置。 特别地，本发明涉及一种用于使用主要径向载荷来扩张支架的方法和装置，从而减少由于在将支架装载到心轴或其它扩张装置上时施加的轴向载荷而产生的应力。 本发明的方法提供了形状记忆支架的逐步扩张，同时降低了支架遭受的总体应力，从而提高了在扩张期间由于断裂的支柱引起的制造产量。
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公开(公告)号：US08187320B2
公开(公告)日：2012-05-29
申请号：US10641787
申请日：2003-08-15
申请人： Stephan Wnendt , Randolf Von Oepen , Bernd Kuttler , Gerhard Lang , Guenter Lorenz , Axel Grandt
发明人： Stephan Wnendt , Randolf Von Oepen , Bernd Kuttler , Gerhard Lang , Guenter Lorenz , Axel Grandt
IPC分类号： A61F2/82
CPC分类号： A61L31/16 , A61L2300/416 , A61L2300/606
摘要： Implants and methods of making same are provided for treatment or prophylaxis of coronary or peripheral vascular constrictions or vascular occlusions, and particularly, stenoses or restenoses, that comprise FK506 in chemically covalently bound, non-covalently bound or physically immobilized form.
摘要翻译： 提供了植入物及其制备方法，用于治疗或预防化学共价结合，非共价结合或物理固定化形式的冠状或外周血管收缩或血管闭塞，特别是狭窄或再狭窄，其包含FK506。
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公开(公告)号：US20120065719A1
公开(公告)日：2012-03-15
申请号：US13220123
申请日：2011-08-29
CPC分类号： A61F2/0095 , A61F2002/9505 , A61F2002/9583 , A61F2002/9665
摘要： Device shields for packaging and protecting medical devices during storage and deployment. A device shield includes a body or housing configured to maintain a medical device and at least a portion of a medical device delivery apparatus within the body or housing, and a limit element having a first constraining position and a second open position.
摘要翻译： 在存储和部署期间用于包装和保护医疗设备的设备屏蔽。 设备屏蔽包括被配置为将医疗设备和医疗设备传送设备的至少一部分保持在主体或外壳内的主体或外壳以及具有第一约束位置和第二打开位置的限制元件。
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公开(公告)号：US08114125B2
公开(公告)日：2012-02-14
申请号：US12117581
申请日：2008-05-08
申请人： Gerd Seibold , Kenneth J. Michlitsch , Randolf Von Oepen , Bodo Quint , Ib Erling Joergensen , Stevan Nielsen , Tommy Conzelmann
发明人： Gerd Seibold , Kenneth J. Michlitsch , Randolf Von Oepen , Bodo Quint , Ib Erling Joergensen , Stevan Nielsen , Tommy Conzelmann
IPC分类号： A61B17/08
CPC分类号： A61B17/0057 , A61B17/0643 , A61B2017/00004 , A61B2017/00477 , A61B2017/00659
摘要： Apparatus is provided for sealing a puncture within a vessel or tissue to provide hemostasis, comprising a first disk coupled to either a second disk or a spring, and sealingly engaged to the vessel or tissue surrounding the puncture. At least the first disk is preferably configured to substantially conform to the profile of the vessel or tissue when deployed. In one embodiment, the disks may be released from engagement with the vessel or tissue to reposition the disks after deployment.
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公开(公告)号：US20110184509A1
公开(公告)日：2011-07-28
申请号：US12694821
申请日：2010-01-27
IPC分类号： A61F2/84
CPC分类号： A61F2/95 , A61F2/958 , A61F2/97 , A61F2002/9583 , A61F2250/0018
摘要： A sheath assembly is provided for protecting a stent mounted on a catheter. An inner tubular member is positioned over the stent without longitudinal movement of the inner tubular member along the stent surface thereby eliminating the possibility of scraping or scratching a drug coating or polymer coating on the stent surface or balloon surface. An outer tubular member slides over the inner tubular member to firmly compress it onto the stent for further protection. In use, the outer tubular member is removed from over the inner tubular member so that the two half-cylindrical portions of the inner tubular member can fall away from the stent without longitudinal movement along the stent surface.
摘要翻译： 提供护套组件用于保护安装在导管上的支架。 内部管状构件被定位在支架上方，而不沿着支架表面的内部管状构件的纵向移动，从而消除刮擦或刮擦支架表面或气囊表面上的药物涂层或聚合物涂层的可能性。 外部管状构件在内部管状构件上滑动以将其牢固地压缩到支架上用于进一步保护。 在使用中，外部管状构件从内部管状构件上方移除，使得内部管状构件的两个半圆柱形部分可以从支架脱落而不沿着支架表面纵向移动。
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公开(公告)号：US07927364B2
公开(公告)日：2011-04-19
申请号：US10859636
申请日：2004-06-03
IPC分类号： A61F2/06
CPC分类号： A61F2/07 , A61F2/82 , A61F2/856 , A61F2/90 , A61F2/91 , A61F2/915 , A61F2/958 , A61F2002/0086 , A61F2002/91508 , A61F2002/91533 , A61F2002/91558 , A61F2220/0008 , A61F2220/0016 , A61F2220/005
摘要： Apparatus and methods for stenting are provided comprising a stent attached to a porous biocompatible material that is permeable to endothelial cell ingrowth, but impermeable to release of emboli of predetermined size. Preferred stent designs are provided, as well as preferred manufacturing techniques. Apparatus and methods are also provided for use at a vessel branching. Moreover, embodiments of the present invention may comprise a coating configured for localized delivery of therapeutic agents. Embodiments of the present invention are expected to provide enhanced embolic protection, improved force distribution, and improved recrossability, while reducing a risk of restenosis and thrombus formation.
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