公开(公告)号：US07201745B2

公开(公告)日：2007-04-10

申请号：US10437713

申请日：2003-05-13

申请人： Kristian DiMatteo ,  Sharon Mi Lyn Tan

发明人： Kristian DiMatteo ,  Sharon Mi Lyn Tan

IPC分类号： A61M25/00

CPC分类号： A61M25/0017

摘要： A catheter extending from a distal end which, when in an operative position is inserted within a body of a patient, to a proximal end, the catheter comprising a charge holding cavity to which a therapeutic compound is to be supplied and a wall including inner and outer portions, an inner surface of the inner portion surrounding the charge holding cavity with an outer portion surrounding at least a portion of an outer surface of the inner portion, wherein the inner portion is formed so that a first diffusion rate of the therapeutic compound therethrough is different from a second diffusion rate through the outer portion.

摘要翻译： 从远端延伸的导管，其在操作位置被插入到患者的身体内时到达近端，所述导管包括电荷保持腔，供给治疗化合物的导管和包括内部和/ 所述内部部分的内表面围绕所述电荷保持腔，外部包围所述内部部分的外表面的至少一部分，其中所述内部部分形成为使得所述治疗化合物通过其中的第一扩散速率 与通过外部的第二扩散速度不同。

公开(公告)号：US07172617B2

公开(公告)日：2007-02-06

申请号：US10046658

申请日：2002-01-14

申请人： Darragh Colgan ,  Peter A. Hamilton ,  Paul DiCarlo ,  Andrew J. Campbell ,  Sean Gilligan ,  Albert Chin ,  Kristian DiMatteo

发明人： Darragh Colgan ,  Peter A. Hamilton ,  Paul DiCarlo ,  Andrew J. Campbell ,  Sean Gilligan ,  Albert Chin ,  Kristian DiMatteo

IPC分类号： A61F2/06 ,  A61F2/00

CPC分类号： A61F2/90 ,  A61F2/07 ,  A61F2/95 ,  A61F2/966 ,  A61F2002/9517 ,  A61F2002/9534 ,  A61F2002/9665 ,  A61F2210/0076 ,  A61F2220/0016 ,  A61F2230/0054 ,  A61F2250/0098

摘要： The present invention relates to a system for delivering a medical prosthesis into a body lumen. A preferred embodiment of the invention utilizes a catheter having a stent mounted at the distal end that is released into the body lumen by movement of an outer sheath covering the stent in the proximal direction. The stent expands to conform to the inner wall of the lumen and the catheter is withdrawn.

摘要翻译： 本发明涉及一种用于将医用假体递送到体腔中的系统。 本发明的优选实施例利用具有安装在远端的支架的导管，其通过在近端方向上覆盖支架的外护套的移动而释放到体腔中。 支架膨胀以符合内腔的内壁，导管被取出。

公开(公告)号：US07122048B2

公开(公告)日：2006-10-17

申请号：US10139127

申请日：2002-05-03

申请人： Kristian DiMatteo ,  Robert C. Thistle

发明人： Kristian DiMatteo ,  Robert C. Thistle

IPC分类号： A61F2/06

CPC分类号： A61F2/07 ,  A61F2/88 ,  A61F2/90 ,  A61F2002/067 ,  A61F2002/075 ,  A61F2220/005 ,  A61F2220/0058 ,  A61F2220/0075

摘要： A self-expanding endoluminal device comprising at least one tubular filamentary member having a hollow core for receiving a guidewire, the tubular member having a straightened configuration with the guidewire in the hollow core and a shape memory configuration without the guidewire in the hollow core. A delivery system includes the guidewire. The hollow core may contain a substance that is adapted to be eluted from the tubular member or permanently contained inside. The device may further comprise a graft. The device may also comprise a plurality of filamentary members, more than one of which may comprise tubular members. The device may also have a severable extension that extends outside of the body through which the substance may be periodically injected.

公开(公告)号：US20050256502A1

公开(公告)日：2005-11-17

申请号：US11170235

申请日：2005-06-28

申请人： Kristian DiMatteo ,  Sharon Tan

发明人： Kristian DiMatteo ,  Sharon Tan

IPC分类号： A61M25/00

CPC分类号： A61M25/0017

摘要： A catheter extending from a distal end which, when in an operative position is inserted within a body of a patient, to a proximal end, the catheter comprising a charge holding cavity to which a therapeutic compound is to be supplied and a wall including inner and outer portions, an inner surface of the inner portion surrounding the charge holding cavity with an outer portion surrounding at least a portion of an outer surface of the inner portion, wherein the inner portion is formed so that a first diffusion rate of the therapeutic compound therethrough is different from a second diffusion rate through the outer portion.

摘要翻译： 从远端延伸的导管，其在操作位置被插入到患者的身体内时到达近端，所述导管包括电荷保持腔，供给治疗化合物的导管和包括内部和/ 所述内部部分的内表面围绕所述电荷保持腔，外部包围所述内部部分的外表面的至少一部分，其中所述内部部分形成为使得所述治疗化合物通过其中的第一扩散速率 与通过外部的第二扩散速度不同。

公开(公告)号：US20050182352A1

公开(公告)日：2005-08-18

申请号：US10777545

申请日：2004-02-12

申请人： Kristian DiMatteo ,  Todd Beaupre ,  James Culhane ,  Benjamin Bell ,  James Weldon

发明人： Kristian DiMatteo ,  Todd Beaupre ,  James Culhane ,  Benjamin Bell ,  James Weldon

IPC分类号： A61M25/00 ,  A61M3/00

CPC分类号： A61M25/003 ,  A61M25/0068 ,  A61M25/0069 ,  A61M25/0074 ,  A61M2025/0031 ,  A61M2025/0037 ,  A61M2025/0073

摘要： A distal tip for a catheter comprises first and second lumens extending therethrough, wherein in an operative configuration, the first and second lumens are coupled to first and second lumens of a dual lumen catheter with a first opening of the distal tip fluidly connected to the first lumen for inflow of fluid from a body lumen into which the distal tip is inserted in a normal mode of operation and for outflow of fluid thereto in a reverse mode of operation and a second opening fluidly connected to the second lumen. The second opening is disposed distally from the first opening and separated therefrom by a selected stagger distance for outflow of fluid therefrom when the catheter is in the normal mode of operation and for inflow of fluid from the body lumen in a reverse mode of operation. The distal tip also includes a contoured flow deflection element directing, in the reverse mode of operation, outflow from the first opening away from the second opening and a contoured outlet portion of the second opening reducing an outflow velocity therefrom in the normal mode of operation.

摘要翻译： 用于导管的远侧末端包括从其延伸穿过的第一和第二腔，其中在操作构型中，所述第一和第二腔与双腔导管的第一和第二腔连接，所述远端的第一开口流体连接到第一腔 流体从腔体流入，其中远侧末端以正常操作模式插入其中，并且以反向操作模式流出流体并且流体连接到第二腔的第二开口。 当导管处于正常操作模式并且以相反的操作模式从体腔流入时，第二开口从第一开口向远侧方向设置并与之分开一个选定的交错距离，用于从其中流出流体。 远侧末端还包括成形的流动偏转元件，其以相反的操作模式引导从第一开口离开第二开口流出，并且第二开口的轮廓出口部分在正常操作模式中减小其流出速度。

公开(公告)号：US20050171502A1

公开(公告)日：2005-08-04

申请号：US10768479

申请日：2004-01-29

申请人： Katie Daly ,  Kristian DiMatteo ,  Eric Houde

发明人： Katie Daly ,  Kristian DiMatteo ,  Eric Houde

IPC分类号： A61M25/00 ,  A61M39/02 ,  A61M39/24 ,  A61M31/00

CPC分类号： A61M39/0208 ,  A61M39/24 ,  A61M2039/0211

摘要： A port for implantation within a body, comprises a housing having a proximal surface, a distal surface and a side surface wherein, when the port is implanted within a body in a desired orientation, the proximal surface faces outward toward the skin, the distal surface faces inward away from the skin and the side surface extends between the proximal and distal surfaces and a first well formed within the housing, the first well including a first opening in the proximal surface. A second well is formed in the housing adjacent to the first well and has a second opening formed in the proximal surface. First and second outlet openings formed on the side surface of the port are in fluid communication with the first and second wells, respectively, and are separated from one another by a distance substantially equal to a distance separating lumens of a dual lumen catheter to which the port is to be connected. In addition, a method of infusing fluids to a patient, comprises attaching a dual lumen catheter to a blood vessel of the patient and implanting subcutaneously a port including first and second openings separated by a distance substantially equal to a distance between the dual lumens of the catheter, wherein the first opening is in fluid communication with a first well of the port and the second opening is in fluid communication with a second well of the port. The dual lumen catheter is then connected to the first and second openings of the port and a first fluid is provided to the first well while a second fluid is provided to the second well.

摘要翻译： 用于植入体内的端口包括具有近端表面，远端表面和侧表面的壳体，其中当端口以期望的取向植入体内时，近端表面朝向皮肤向外，远端表面 面向内部远离皮肤并且侧表面在近端表面和远端表面之间延伸，并且在壳体内形成第一阱，第一阱包括近端表面中的第一开口。 第二孔形成在邻近第一井的壳体中并且具有形成在近侧表面中的第二开口。 形成在端口的侧表面上的第一和第二出口开口分别与第一和第二孔流体连通，并且彼此分开一段距离，该距离基本上等于分隔两腔导管的内腔的距离， 端口要连接。 另外，向患者输注流体的方法包括将双腔导管附接到患者的血管，并将皮下植入包括第一和第二开口的端口，所述口与所述口腔的双腔之间的距离基本相等 导管，其中所述第一开口与所述端口的第一孔流体连通，并且所述第二开口与所述端口的第二孔流体连通。 然后将双腔导管连接到端口的第一和第二开口，并且将第一流体提供到第一阱，而将第二流体提供给第二阱。

公开(公告)号：US08845714B2

公开(公告)日：2014-09-30

申请号：US13160105

申请日：2011-06-14

申请人： Kristian DiMatteo ,  John Spiridigliozzi ,  Robert C. Thistle

发明人： Kristian DiMatteo ,  John Spiridigliozzi ,  Robert C. Thistle

IPC分类号： A61F2/06 ,  A61F2/07 ,  A61F2/90

CPC分类号： A61F2/07 ,  A61F2/90 ,  A61F2002/065 ,  A61F2002/075 ,  A61F2220/005 ,  A61F2220/0058 ,  A61F2220/0075

摘要： An endovascular prosthesis of the present invention includes an expandable stent and a means for sealably attaching a tubular graft to the stent within the stent's lumen. The means of sealably attaching a graft includes membranes, foams, polymeric materials and combinations thereof. Additionally, the present invention includes methods of forming an endovascular prosthesis and methods of implanting an endovascular prosthesis within a vessel to provide sealable securement of a tubular graft within the stent's lumen.

摘要翻译： 本发明的血管内假体包括可扩张支架和用于将管状移植物密封地附接到支架内的支架内的装置。 可密封地连接移植物的方法包括膜，泡沫，聚合材料及其组合。 另外，本发明包括形成血管内假体的方法和在血管内植入血管内假体以提供管状移植物在支架内腔内的可密封固定的方法。

公开(公告)号：US08702754B2

公开(公告)日：2014-04-22

申请号：US11855728

申请日：2007-09-14

申请人： Kristian DiMatteo ,  Chris Kilburn-Peterson ,  Nathan S. Cauldwell ,  Jonathan Howe ,  Hugh S. West

发明人： Kristian DiMatteo ,  Chris Kilburn-Peterson ,  Nathan S. Cauldwell ,  Jonathan Howe ,  Hugh S. West

IPC分类号： A61B17/04

CPC分类号： A61B17/0401 ,  A61B17/863 ,  A61B2017/0409 ,  A61B2017/044

摘要： Methods and devices are provided for anchoring suture to bone. In one exemplary embodiment, a cannulated suture anchor is provided and it includes a suture-engaging member formed therein and configured to receive a suture therearound such that trailing ends of the suture can extend through the suture anchor. The suture anchor can also include at least a proximal portion having dual threads to facilitate engagement with bone. The present invention also provides exemplary sutures and drivers that can be used with the various methods and devices disclosed herein, or with other methods and devices known in the art.

摘要翻译： 提供了将缝合线锚定到骨头上的方法和装置。 在一个示例性实施例中，提供了一种插管缝合锚，并且其包括形成在其中的缝合线接合构件，并且构造成在其周围接收缝合线，使得缝合线的后端可延伸穿过缝合线锚。 缝合锚固件还可以包括至少一个具有双螺纹以便于与骨接合的近端部分。 本发明还提供可以与本文公开的各种方法和装置一起使用的示例性缝线和驱动器，或与本领域已知的其它方法和装置一起使用。

公开(公告)号：US20130325011A1

公开(公告)日：2013-12-05

申请号：US13487586

申请日：2012-06-04

申请人： Benjamin Cleveland ,  Kristian DiMatteo ,  Erik S. Sojka ,  Christopher G. Weinert ,  Jose E. Lizardi

发明人： Benjamin Cleveland ,  Kristian DiMatteo ,  Erik S. Sojka ,  Christopher G. Weinert ,  Jose E. Lizardi

IPC分类号： A61B17/16 ,  A61B17/04 ,  A61B17/56

CPC分类号： A61B17/1796 ,  A61B17/0482 ,  A61B17/0485 ,  A61B17/16 ,  A61B17/1684 ,  A61B17/1714 ,  A61B17/1778 ,  A61B17/86 ,  A61B17/8875 ,  A61B2017/00407 ,  A61F2/0811 ,  A61F2002/0852 ,  A61F2002/0882 ,  A61F2002/0888

摘要： Methods and devices are provided for forming bone tunnels. In general, the methods and devices allow multiple converging tunnels to be formed in bone, such as in an arthroscopic surgical procedure, e.g., a rotator cuff repair surgical procedure. One or more sutures can be advanced through the converging tunnels, and the suture(s) can be coupled to tissue. The suture(s) with the tissue coupled thereto can be tensioned, thereby helping to maximize an amount of the tissue in contact with the bone. In an exemplary embodiment, a guide device is provided that can be configured to allow a first tunnel to be formed in bone and to allow a plurality of additional tunnels to be formed in the bone at predetermined angular positions relative to the first tunnel such that each of the additional tunnels can extend transverse to the first tunnel and intersect the first tunnel.

摘要翻译： 提供了形成骨隧道的方法和装置。 通常，所述方法和装置允许在骨中形成多个会聚隧道，例如在关节镜外科手术中，例如肩袖修复外科手术。 一个或多个缝合线可以通过会聚隧道前进，并且缝合线可以联接到组织。 具有与其结合的组织的缝合线可以被张紧，从而有助于使与骨接触的组织的量最大化。 在示例性实施例中，提供了引导装置，其可被配置为允许在骨中形成第一隧道并且允许在相对于第一隧道的预定角度位置处在骨头中形成多个附加隧道，使得每个 的附加隧道可以横向于第一隧道延伸并与第一隧道相交。

公开(公告)号：US20130023921A1

公开(公告)日：2013-01-24

申请号：US13603835

申请日：2012-09-05

申请人： Kristian DiMatteo

发明人： Kristian DiMatteo

IPC分类号： A61F2/01

CPC分类号： A61F2/01 ,  A61B2017/1205 ,  A61B2090/037 ,  A61F2002/011 ,  A61F2002/016 ,  A61F2230/005 ,  A61F2230/0067 ,  A61F2230/008 ,  A61F2250/0071

摘要： A thrombus filter which can be securely fixed at a selected location in the vascular system of a patient and removed when no longer required. The thrombus filter includes a body portion and a plurality of struts, each strut having a joined end and a free end. The joined end of each strut is fixably attached to the body portion. The struts radiate outwardly from the body member such that the thrombus filter is generally conical in shape. The free end of each strut includes an anchor member. A weakened portion is disposed proximate the free end of each strut. When removal of the thrombus filter is desired, forces are applied to the thrombus filter causing the struts to break at the weakened portions proximate the free ends.

摘要翻译： 一种血栓过滤器，其可以牢固地固定在患者的血管系统中的选定位置，并且在不再需要时被去除。 血栓过滤器包括主体部分和多个支柱，每个支柱具有连接端和自由端。 每个支柱的连接端可固定地附接至主体部分。 支柱从身体构件向外辐射，使得血栓过滤器通常为锥形。 每个支柱的自由端包括锚定构件。 弱化部分靠近每个支柱的自由端设置。 当需要去除血栓过滤器时，将力施加到血栓过滤器，导致支柱在靠近自由端的弱化部分断裂。