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公开(公告)号:US20090242430A1
公开(公告)日:2009-10-01
申请号:US12366471
申请日:2009-02-05
IPC分类号: G01N27/26
CPC分类号: G01N27/3277 , B82Y15/00 , B82Y30/00 , G01N33/5438 , G01N33/58 , G01N33/84 , G01N2458/30 , G01N2800/04
摘要: The present invention is directed to the detection of target analytes using electronic techniques, particularly AC techniques.
摘要翻译: 本发明涉及使用电子技术,特别是AC技术检测目标分析物。
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公开(公告)号:US07514228B2
公开(公告)日:2009-04-07
申请号:US11832792
申请日:2007-08-02
申请人: Thomas J. Meade
发明人: Thomas J. Meade
CPC分类号: B82Y30/00 , B82Y5/00 , B82Y15/00 , G01N33/542 , G01N33/5438
摘要: The invention relates to novel methods and compositions for the detection of analytes using the nuclear reorganization energy, λ, of an electron transfer process.
摘要翻译: 本发明涉及使用电子转移方法的核重组能量λ检测分析物的新方法和组合物。
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公开(公告)号:US20080237061A1
公开(公告)日:2008-10-02
申请号:US11981735
申请日:2007-10-30
CPC分类号: G01N27/3277 , B82Y15/00 , B82Y30/00 , G01N33/5438 , G01N33/58 , G01N33/84 , G01N2458/30 , G01N2800/04
摘要: The present invention is directed to the detection of target analytes using electronic techniques, particularly AC techniques.
摘要翻译: 本发明涉及使用电子技术,特别是AC技术检测目标分析物。
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公开(公告)号:US20080173553A1
公开(公告)日:2008-07-24
申请号:US11978971
申请日:2007-10-30
申请人: Thomas J. Meade
发明人: Thomas J. Meade
IPC分类号: G01N27/00
CPC分类号: B82Y30/00 , B82Y5/00 , B82Y15/00 , G01N33/542 , G01N33/5438
摘要: The invention relates to novel methods and compositions for the detection of analytes using the nuclear reorganization energy, λ, of an electron transfer process.
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公开(公告)号:US07384749B2
公开(公告)日:2008-06-10
申请号:US11343462
申请日:2006-01-30
摘要: The invention relates to nucleic acids covalently coupled to electrodes via conductive oligomers. More particularly, the invention is directed to the site-selective modification of nucleic acids with electron transfer moieties and electrodes to produce a new class of biomaterials, and to methods of making and using them.
摘要翻译: 本发明涉及通过导电低聚物共价偶联到电极上的核酸。 更具体地,本发明涉及具有电子转移部分和电极的核酸的位点选择性修饰以产生新类别的生物材料,以及制备和使用它们的方法。
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公开(公告)号:US07045285B1
公开(公告)日:2006-05-16
申请号:US09557577
申请日:2000-04-21
摘要: The invention relates to nucleic acids covalently coupled to electrodes via conductive oligomers. More particularly, the invention is directed to the site-selective modification of nucleic acids with electron transfer moieties and electrodes to produce a new class of biomaterials, and to methods of making and using them.
摘要翻译: 本发明涉及通过导电低聚物共价偶联到电极上的核酸。 更具体地,本发明涉及具有电子转移部分和电极的核酸的位点选择性修饰以产生新类别的生物材料,以及制备和使用它们的方法。
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公开(公告)号:US07018523B2
公开(公告)日:2006-03-28
申请号:US09841809
申请日:2001-04-24
申请人: Thomas J. Meade
发明人: Thomas J. Meade
CPC分类号: B82Y30/00 , B82Y5/00 , B82Y15/00 , G01N33/542 , G01N33/5438
摘要: The invention relates to novel methods and compositions for the detection of analytes using the nuclear reorganization energy, λ, of an electron transfer process.
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88.
公开(公告)号:US07014992B1
公开(公告)日:2006-03-21
申请号:US08873978
申请日:1997-06-12
CPC分类号: C07H21/00 , C12Q1/6825
摘要: The invention relates to nucleic acids covalently coupled to electrodes via conductive oligomers. More particularly, the invention is directed to the site-selective modification of nucleic acids with electron transfer moieties and electrodes to produce a new class of biomaterials, and to methods of making and using them.
摘要翻译: 本发明涉及通过导电低聚物共价偶联到电极上的核酸。 更具体地,本发明涉及具有电子转移部分和电极的核酸的位点选择性修饰以产生新类别的生物材料,以及制备和使用它们的方法。
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89.
公开(公告)号:US06780856B2
公开(公告)日:2004-08-24
申请号:US09828499
申请日:2001-04-06
申请人: Thomas J. Meade , Ofer Blum , Harry B. Gray
发明人: Thomas J. Meade , Ofer Blum , Harry B. Gray
IPC分类号: A61K3133
CPC分类号: C07F15/06 , C07F15/065
摘要: The invention relates to methods of stabilizing in an aqueous medium cobalt (III) Schiff base complexes and stabilized cobalt (III) Schiff base compounds therefrom.
摘要翻译: 本发明涉及在含水介质中稳定钴(III)席夫碱络合物和稳定的(III)席夫碱化合物的方法。
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公开(公告)号:US06761816B1
公开(公告)日:2004-07-13
申请号:US09520477
申请日:2000-03-08
申请人: Gary Blackburn , Stephen E. Creager , Scott Fraser , Bruce D. Irvine , Thomas J. Meade , Stephen D. O'Connor , Robert H. Terbrueggen , Jost G. Vielmetter , Thomas W. Welch
发明人: Gary Blackburn , Stephen E. Creager , Scott Fraser , Bruce D. Irvine , Thomas J. Meade , Stephen D. O'Connor , Robert H. Terbrueggen , Jost G. Vielmetter , Thomas W. Welch
IPC分类号: G01N27327
CPC分类号: B82Y30/00 , B82Y15/00 , C12Q1/6825 , C12Q2565/629
摘要: The invention relates to compositions and methods useful in the acceleration of binding of target analytes to capture ligands on surfaces. Detection proceeds through the use of an electron transfer moiety (ETM) that is associated with the target analyte, either directly or indirectly, to allow electronic detection of the ETM.
摘要翻译: 本发明涉及用于加速目标分析物与表面捕获配体结合的组合物和方法。 检测通过直接或间接使用与目标分析物相关的电子转移部分(ETM)进行,以允许电子检测ETM。
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