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公开(公告)号：US20140322706A1
公开(公告)日：2014-10-30
申请号：US14062860
申请日：2013-10-24
申请人： Jon Faiz KAYYEM , Jay Srinivasan
发明人： Jon Faiz KAYYEM , Jay Srinivasan
IPC分类号： C12Q1/68
CPC分类号： G01N35/00722 , B01L3/502715 , B01L3/50273 , B01L3/502761 , B01L7/525 , B01L2200/0621 , B01L2200/0631 , B01L2200/10 , B01L2200/16 , B01L2300/044 , B01L2300/0672 , B01L2300/0816 , B01L2300/123 , B01L2400/0427 , B01L2400/0481 , B01L2400/0683 , G01N35/00732 , G01N2035/00019 , G01N2035/00366 , G01N2035/00752 , G01N2035/0091
摘要： This invention provides biochip cartridges and instrument devices for the detection and/or analysis of target analytes from patient samples.
摘要翻译： 本发明提供用于从患者样品检测和/或分析目标分析物的生物芯片盒和仪器装置。
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公开(公告)号：US08486247B2
公开(公告)日：2013-07-16
申请号：US11981541
申请日：2007-10-30
申请人： Jon Faiz Kayyem
发明人： Jon Faiz Kayyem
IPC分类号： G01N27/447 , G01N27/453 , G01N27/327
CPC分类号： G01N27/44791 , B01L3/5027 , B01L3/502715 , B01L3/50273 , B01L3/502738 , B01L3/502761 , B01L7/52 , B01L7/525 , B01L9/527 , B01L2200/10 , B01L2300/021 , B01L2300/0636 , B01L2300/0645 , B01L2300/0816 , B01L2300/0877 , B01L2300/0887 , B01L2400/0415 , B01L2400/0418 , B01L2400/0439 , B01L2400/0442 , B01L2400/0481 , B01L2400/0487 , B01L2400/0611 , B01L2400/0633 , B01L2400/0638 , B01L2400/0677 , B82Y30/00 , B82Y35/00 , B82Y40/00 , C12Q1/6813 , C12Q1/6825 , G01N27/3275 , G01N27/3276 , G01N27/447 , G01N27/4473 , G01N27/44752 , G01N33/5302 , G01N33/5438 , G01N33/54386 , G01N2035/00158 , G01N2610/00 , C12Q2565/629 , C12Q2563/113
摘要： The invention relates generally to methods and apparatus for conducting analyses, particularly microfluidic devices for the detection of target analytes.
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公开(公告)号：US20120199499A1
公开(公告)日：2012-08-09
申请号：US13366068
申请日：2012-02-03
IPC分类号： G01N27/26
CPC分类号： G01N27/3277 , B82Y15/00 , B82Y30/00 , G01N33/5438 , G01N33/58 , G01N33/84 , G01N2458/30 , G01N2800/04
摘要： The present invention is directed to the detection of target analytes using electronic techniques, particularly AC techniques.
摘要翻译： 本发明涉及使用电子技术，特别是AC技术检测目标分析物。
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公开(公告)号：US07851146B2
公开(公告)日：2010-12-14
申请号：US10279742
申请日：2002-10-23
申请人： Thomas J Meade , Jon Faiz Kayyem , Scott E Fraser
发明人： Thomas J Meade , Jon Faiz Kayyem , Scott E Fraser
CPC分类号： C12Q1/6825 , C07H21/00 , C07H23/00 , C12Q1/6818 , C12Q2563/113 , C12Q2565/101
摘要： The present invention provides for the selective covalent modification of nucleic acids with redox active moieties such as transition metal complexes. Electron donor and electron acceptor moieties are covalently bound to the ribose-phosphate backbone of a nucleic acid at predetermined positions. The resulting complexes represent a series of new derivatives that are bimolecular templates capable of transferring electrons over very large distances at extremely fast rates. These complexes possess unique structural features which enable the use of an entirely new class of bioconductors and photoactive probes.
摘要翻译： 本发明提供了用氧化还原活性部分如过渡金属配合物选择性共价修饰核酸。 电子供体和电子受体部分在预定位置与核酸的核糖 - 磷酸骨架共价结合。 所得的复合物表示一系列新的衍生物，其是能够以非常快的速率在非常大的距离上转移电子的双分子模板。 这些复合物具有独特的结构特征，可以使用全新的生物传感器和光敏探针。
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公开(公告)号：US07601507B2
公开(公告)日：2009-10-13
申请号：US11981645
申请日：2007-10-30
IPC分类号： G01N33/53
CPC分类号： G01N27/3277 , B82Y15/00 , B82Y30/00 , G01N33/5438 , G01N33/58 , G01N33/84 , G01N2458/30 , G01N2800/04
摘要： The present invention is directed to the detection of target analytes using electronic techniques, particularly AC techniques.
摘要翻译： 本发明涉及使用电子技术，特别是AC技术检测目标分析物。
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公开(公告)号：US07560237B2
公开(公告)日：2009-07-14
申请号：US09096593
申请日：1998-06-12
IPC分类号： G01N33/53
CPC分类号： G01N27/3277 , B82Y15/00 , B82Y30/00 , G01N33/5438 , G01N33/58 , G01N33/84 , G01N2458/30 , G01N2800/04
摘要： The present invention is directed to the detection of target analytes using electronic techniques, particularly AC techniques.
摘要翻译： 本发明涉及使用电子技术，特别是AC技术检测目标分析物。
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7.发明授权Use of microfluidic systems in the electrochemical detection of target analytes 有权在目标分析物的电化学检测中使用微流体系统公开(公告)号：US07534331B2
公开(公告)日：2009-05-19
申请号：US11043515
申请日：2005-01-25
申请人： Jon Faiz Kayyem
发明人： Jon Faiz Kayyem
IPC分类号： G01N27/327
CPC分类号： G01N27/44791 , B01L3/5027 , B01L3/502715 , B01L3/50273 , B01L3/502738 , B01L3/502761 , B01L7/52 , B01L7/525 , B01L9/527 , B01L2200/10 , B01L2300/021 , B01L2300/0636 , B01L2300/0645 , B01L2300/0816 , B01L2300/0877 , B01L2300/0887 , B01L2400/0415 , B01L2400/0418 , B01L2400/0439 , B01L2400/0442 , B01L2400/0481 , B01L2400/0487 , B01L2400/0611 , B01L2400/0633 , B01L2400/0638 , B01L2400/0677 , B82Y30/00 , B82Y35/00 , B82Y40/00 , C12Q1/6813 , C12Q1/6825 , G01N27/3275 , G01N27/3276 , G01N27/447 , G01N27/4473 , G01N27/44752 , G01N33/5302 , G01N33/5438 , G01N33/54386 , G01N2035/00158 , G01N2610/00 , C12Q2565/629 , C12Q2563/113
摘要： The invention relates generally to methods and apparatus for conducting analyses, particularly microfluidic devices for the detection of target analytes.
摘要翻译： 本发明一般涉及用于进行分析的方法和装置，特别是用于检测目标分析物的微流体装置。
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公开(公告)号：US20090057147A1
公开(公告)日：2009-03-05
申请号：US11982403
申请日：2007-10-31
申请人： Jon Faiz Kayyem
发明人： Jon Faiz Kayyem
CPC分类号： G01N27/44791 , B01L3/5027 , B01L3/502715 , B01L3/50273 , B01L3/502738 , B01L3/502761 , B01L7/52 , B01L7/525 , B01L9/527 , B01L2200/10 , B01L2300/021 , B01L2300/0636 , B01L2300/0645 , B01L2300/0816 , B01L2300/0877 , B01L2300/0887 , B01L2400/0415 , B01L2400/0418 , B01L2400/0439 , B01L2400/0442 , B01L2400/0481 , B01L2400/0487 , B01L2400/0611 , B01L2400/0633 , B01L2400/0638 , B01L2400/0677 , B82Y30/00 , B82Y35/00 , B82Y40/00 , C12Q1/6813 , C12Q1/6825 , G01N27/3275 , G01N27/3276 , G01N27/447 , G01N27/4473 , G01N27/44752 , G01N33/5302 , G01N33/5438 , G01N33/54386 , G01N2035/00158 , G01N2610/00 , C12Q2565/629 , C12Q2563/113
摘要： The invention is directed to devices that allow for simultaneous multiple biochip analysis. In particular, the devices are configured to hold multiple cartridges comprising biochips comprising arrays such as nucleic acid arrays, and allow for high throughput analysis of samples.
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公开(公告)号：US07160678B1
公开(公告)日：2007-01-09
申请号：US09452277
申请日：1999-11-30
CPC分类号： B82Y15/00 , B82Y30/00 , B82Y40/00 , C12Q1/6825 , C12Q2565/519 , C12Q2563/113
摘要： The present invention relates to the use of self-assembled monolayers with mixtures of conductive oligomers and insulators to detect target analytes.
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公开(公告)号：US07090804B2
公开(公告)日：2006-08-15
申请号：US09238351
申请日：1999-01-27
申请人： Jon Faiz Kayyem , Cynthia Bamdad
发明人： Jon Faiz Kayyem , Cynthia Bamdad
CPC分类号： B01D24/105 , B01D17/0214 , B01D17/045 , B01D24/4642 , B01D24/48 , B01D35/12 , B82Y15/00 , B82Y30/00 , C02F1/283 , C12Q1/6825 , C12Q1/6874 , G01N27/3277 , C12Q2565/101 , C12Q2525/313 , C12Q2525/113 , C12Q2565/607
摘要： The invention relates to compositions and methods useful in the detection of nucleic acids using a variety of amplification techniques, including both signal amplification and target amplification. Detection proceeds through the use of an electron transfer moiety (ETM) that is associated with the nucleic acid, either directly or indirectly, to allow electronic detection of the ETM using an electrode.
摘要翻译： 本发明涉及用于使用多种扩增技术检测核酸的组合物和方法，包括信号放大和靶扩增两者。 检测通过直接或间接使用与核酸相关联的电子转移部分（ETM）进行，以允许使用电极电子检测ETM。
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