Pharmaceutical composition including laminin fragments to treat or prevent the disease, disorder or symptom of tooth dentin and/or dental pulp

    公开(公告)号:US20230190882A1

    公开(公告)日:2023-06-22

    申请号:US18057110

    申请日:2022-11-18

    申请人: Takashi Saito

    IPC分类号: A61K38/39 A61K38/01 A61K33/42

    摘要: A tooth dentin, pulp or pulp tissue composition for treating or preventing a disease, disorder, or symptom of a tooth dentin and/or pulp or pulp tissue includes: (a) an integrin binding fragment of Laminin, the Laminin being selected from the group consisting of Laminin 511 and Laminin 411, the integrin binding fragment comprising an integrin-binding domain of the Laminin; and (b) a mixture of odontoblast and mineralized nodules secreted from the odontoblast. A coating density of the integrin binding fragment is 1 to 8 μg/cm2. The material (b) has been mixed with the material (a) in the composition so as to form pulp capping applicable to a tooth, such that the composition is able to treat or prevent the disease, disorder or symptom of the tooth dentin and/or pulp tissue including dental caries when applied to the tooth.

    Sheet processing device and image forming device provided with the same

    公开(公告)号:US10131107B2

    公开(公告)日:2018-11-20

    申请号:US15202010

    申请日:2016-07-05

    摘要: The present invention is to provide a sheet processing device including: a receiving tray capable of accommodating therein a sheet having, at a part thereof, a protruding portion and a sheet not having the protruding portion in a mixed state; a first binding member that binds the accommodated sheet bundle at a substantially center thereof in a sheet conveying direction; a folding section that folds the sheet bundle bound by the first binding member in two; and a second binding member that binds protruding portions of the sheet bundle folded by the folding section on a fore edge side of the sheet bundle. With this configuration, the fore edge side of the folded and saddle-stitched sheet bundle can be bound by temporary binding. Thus, a sheet processing device capable of ensuring the security of a saddle-stitched sheet bundle can be provided.

    Abnormality determination device and method of longitudinal acceleration sensor
    90.
    发明授权
    Abnormality determination device and method of longitudinal acceleration sensor 有权
    纵向加速度传感器异常判定装置及方法

    公开(公告)号:US08831819B2

    公开(公告)日:2014-09-09

    申请号:US13637407

    申请日:2011-04-14

    摘要: The running control device and method according to the present invention are those for determining abnormality of a longitudinal acceleration sensor which detects vehicular longitudinal acceleration that is used in a vehicle running control. An integrated value of a vehicular longitudinal acceleration that is detected by the longitudinal acceleration sensor is calculated, and determination whether or not the longitudinal acceleration sensor is abnormal is conducted on the basis of the integrated value and a vehicle speed based on vehicle wheel speeds. The calculation of the integrated value is initiated when a situation where the vehicle speed based on vehicle wheel speeds is zero and the increasing rate of the detected vehicular longitudinal acceleration is equal to or larger than a reference value for the increasing rate continues for a period which is equal to or larger than a reference value for the initiation of calculation.

    摘要翻译: 根据本发明的运行控制装置和方法是用于确定检测车辆行驶控制中使用的车辆纵向加速度的纵向加速度传感器的异常的运行控制装置和方法。 计算由纵向加速度传感器检测到的车辆纵向加速度的积分值,并且基于车辆速度的积分值和车速来进行纵向加速度传感器是否异常的判定。 当基于车轮速度的车辆速度为零并且检测到的车辆纵向加速度的增加率等于或大于增加率的参考值的情况下,开始积分值的计算,持续一段时间 等于或大于开始计算的参考值。