摘要:
The present invention provides a compound of formula I and the use thereof for the therapeutic treatment of disorders relating to or affected by the 5-HT6 receptor.
摘要:
An optical header for coupling a light source to an optical fiber is disclosed. The header preferably includes a ceramic substrate that has a recess for a vertical cavity surface emitting laser (VCSEL), or alternatively an edge emitting laser. An optical fiber is preferably attached to a ceramic substrate and terminates at a light source. The end of the fiber is preferably cleaved or polished to an angle such that light entering the fiber from the light source is substantially reflected into the fiber. A reflective coating is placed on the cleaved end of the fiber thereby permitting a small percentage of light to radiate away from the fiber and toward an intensity detector. The light preferably travels to the detector through a transmission medium such as a prism or an optical-grade epoxy. The header is particularly useful when used in conjunction with multiple fibers simultaneously to form an optical fiber array. The header is also useful to house an optical receiver, or to form a bi-directional header suitable for fiber optic communications.
摘要:
Novel N-sulfinyl-2-carboxyaziridine compounds and novel N-hydrogen-2-hydroxymethylaziridine compounds are provided. The asymmetric synthesis of N-sulfinylaziridines is readily accomplished in high diastereomeric purity and good yield by the Darzens-type reaction of the metal enolate of an .alpha.-haloester and an enantiopure sulfinimine. Ring-opening of these aziridines affords .alpha.-amino acids and the otherwise difficult to prepare syn-.beta.-hydroxy-.alpha.-amino acids, both key structural units found in many bioactive materials. The N-sulfinyl radical may be selectively removed from the novel aziridine compounds by treatment with acid or base. Alternatively, the N-sulfinyl radical may be oxidized to provide the corresponding N-sulfonyl-aziridine, or reduced to form the corresponding 1H-2-hydroxymethylaziridine, either of which may subsequently be ring-opened to provide precursors to bioactive compounds.
摘要:
FIG. 1 is a front and bottom perspective view of an engine, showing my new design; FIG. 2 is a rear and top perspective view thereof; FIG. 3 is a front elevation view thereof; FIG. 4 is a rear elevation view thereof; FIG. 5 is a left side elevation view thereof; FIG. 6 is a right side elevation view thereof; FIG. 7 is a top plan view thereof; and, FIG. 8 is a bottom plan view thereof. The broken lines in the figures illustrate portions of the engine that form no part of the claimed design.
摘要:
This disclosure provides an isolated or purified decellularized liver extracellular matrix (DLM) composition containing an isolated or purified cell capable of differentiating into a hepatocyte and/or liver tissue, and methods for its use in vitro and in vivo.
摘要:
Methods, apparatuses, and computer program products for synchronously debugging a software program using a plurality of virtual machines are provided. Embodiments include controlling, by a master debugging module operating on a first virtual machine, execution of the software program within the first virtual machine; controlling, by a slave debugging module operating on a second virtual machine, execution of the software program within the second virtual machine including delaying execution of the software program within the second virtual machine relative to the execution of the software program within the first virtual machine; detecting, by the master debugging module, an error in the execution of the software program within the first virtual machine; and in response to the detection of the error, capturing, by a hypervisor, a snapshot of the second virtual machine.
摘要:
The present invention relates to the field of natural drugs, particularly to 6-shogaol for using in a method for the treatment of leukemia. The present invention provides a method for treating leukemia by applying a therapeutically effective dose of 6-shogaolt and this therapeutic method can be used for treating leukemia in mammals including human being.
摘要:
The present invention provides a compound of formula I and the use thereof for the therapeutic treatment, prevention or amelioration of a disease or disorder characterized by elevated β-amyloid deposits or β-amyloid levels in a patient.
摘要:
A test system for testing a pair of telecommunications access networks, e.g. as part of transfer engineering. The system comprises a test head for connection, via an access arrangement, to first and second access networks. In a first phase, the access arrangement is arranged to connect the test head to the first access network for sending a first request from the tester to, for example, a CLI server via the first access network. The first request comprises a parameter associated with a user line. The tester is arranged to receive in response to the first request a first identifier from the server. In a second phase, the access arrangement is arranged to connect the test head to the second access network for sending a second request from the test head through the second access network to, for example, a CLI server. The second request also comprises the parameter. The tester is arranged to receive, in response to the second request, a second identifier from the target server and is arranged to carry out a comparison operation involving the first and second identifiers received in response to the two requests. A mismatch can indicate a fault or misconnection in either access network or a problem with network configuration data.
摘要:
The present invention provides a compound of formula I and the use thereof for the therapeutic treatment of disorders relating to or affected by the 5-HT6 receptor.