公开(公告)号：US07252972B2

公开(公告)日：2007-08-07

申请号：US10673860

申请日：2003-09-30

申请人： Yoshimi Kikuchi ,  Masayo Date ,  Yukiko Umezawa ,  Keiichi Yokoyama ,  Haruo Heima ,  Hiroshi Matsui

发明人： Yoshimi Kikuchi ,  Masayo Date ,  Yukiko Umezawa ,  Keiichi Yokoyama ,  Haruo Heima ,  Hiroshi Matsui

IPC分类号： C12P21/04 ,  C12N1/21

CPC分类号： C07K14/36 ,  C07K5/1016 ,  C07K14/195 ,  C07K14/34 ,  C07K2319/00 ,  C12N15/77

摘要： The object of the present invention is to provide a method of producing a heterologous protein by making a coryneform bacterium to produce and efficiently extracellularly secrete (secreto-production) an industrially useful heterologous protein. According to the present invention, a genetic construct is used where a gene sequence encoding an intended protein which is ligated to the downstream of a sequence encoding the signal peptide derived from a coryneform bacterium, the gene construct is introduced into a mutant coryneform bacterium which has a capacity of secreting the heterologous protein at least 2-fold higher than the wild type Corynebacterium glutamicum ATCC 13869, the mutant coryneform bacterium is cultured and the extracellularly released heterologous protein is recovered.

摘要翻译： 本发明的目的是提供通过使棒状细菌产生并有效地细胞外分泌（分泌产生）工业上有用的异源蛋白质来产生异源蛋白质的方法。 根据本发明，使用遗传构建体，其中将编码预期蛋白质的基因序列连接到编码衍生自棒状杆菌型细菌的信号肽的序列的下游，所述基因构建体被引入到突变型棒状杆菌型细菌中 分泌异源蛋白质的能力比野生型谷氨酸棒杆菌ATCC 13869高至少2倍，培养突变棒杆菌型细菌，并回收细胞外释放的异源蛋白质。

公开(公告)号：US20070125420A1

公开(公告)日：2007-06-07

申请号：US10566985

申请日：2004-08-03

申请人： Tetsuya Ezure ,  Nobuo Tanabe ,  Hiroshi Matsui ,  Kenichi Okada

发明人： Tetsuya Ezure ,  Nobuo Tanabe ,  Hiroshi Matsui ,  Kenichi Okada

IPC分类号： H01L31/00

CPC分类号： H01M14/005 ,  H01G9/2031 ,  H01G9/2077 ,  Y02E10/542 ,  Y02P70/521

摘要： A photoelectric conversion element is provided. The photoelectric conversion element includes a casing; and a stacked body enclosed within the casing, wherein the stacked body comprises: a working electrode having a porous oxide semiconductor layer having a sensitizing dye supported on a surface thereof; a counter electrode provided on a side of the porous oxide semiconductor layer of the working electrode facing the working electrode; and an electrolyte layer at least a part of which is formed between the working electrode and the counter electrode, and wherein an upper surface and a lower surface of the stacked body contacts directly or indirectly an inner surface of the casing, the portion of the casing at least contacting the working electrode being made of a material having an optical characteristic of transmitting sunlight.

摘要翻译： 提供光电转换元件。 光电转换元件包括壳体; 以及包围在所述壳体内的层叠体，其中，所述层叠体包括：具有多孔氧化物半导体层的工作电极，所述多孔氧化物半导体层具有负载在其表面上的敏化染料; 设置在面向工作电极的工作电极的多孔氧化物半导体层一侧的对电极; 至少一部分形成在工作电极和对电极之间的电解质层，其中层叠体的上表面和下表面直接或间接地接触壳体的内表面，壳体的一部分 至少接触由具有透射阳光的光学特性的材料制成的工作电极。

公开(公告)号：US20060107997A1

公开(公告)日：2006-05-25

申请号：US11281411

申请日：2005-11-18

申请人： Hiroshi Matsui ,  Nobuo Tanabe

发明人： Hiroshi Matsui ,  Nobuo Tanabe

IPC分类号： H01L31/00

CPC分类号： H01G9/2022 ,  B82Y10/00 ,  H01G9/2031 ,  H01G9/2059 ,  H01G9/2095 ,  H01L51/0037 ,  H01L51/0046 ,  H01L51/0048 ,  H01L51/0052 ,  H01L51/445 ,  Y02E10/542 ,  Y02P70/521

摘要： An electrode according to the present invention includes a substrate, and a conductive layer containing carbon particles or platinum particles and a conductive binder for binding the carbon particles or platinum particles formed above the substrate. By binding the carbon particles or the platinum particles with the conductive binder, it is possible to form an electrode with a porous structure where spaces that communicate with a surface of the conductive layer are defined between the corresponding carbon particles or platinum particles, thereby increasing the effective area (surface area) of the electrode. The photoelectric conversion elements and the dye-sensitized photovoltaic or solar cells according to the present invention can be manufactured at a low cost and have an increased effective area, making it possible to obtain excellent photoelectric conversion efficiency.

公开(公告)号：US07049726B2

公开(公告)日：2006-05-23

申请号：US10377740

申请日：2003-03-04

申请人： Yuuji Nakahara ,  Naohiro Oketani ,  Katsumi Adachi ,  Akira Morishita ,  Hiroshi Matsui ,  Tsuyoshi Takahashi ,  Takushi Takizawa ,  Yoshihito Asao

发明人： Yuuji Nakahara ,  Naohiro Oketani ,  Katsumi Adachi ,  Akira Morishita ,  Hiroshi Matsui ,  Tsuyoshi Takahashi ,  Takushi Takizawa ,  Yoshihito Asao

IPC分类号： H02K1/12

CPC分类号： H02K1/16 ,  Y10T29/49009

摘要： The invention provides a stator for a dynamo-electric machine capable of preventing deterioration of efficiency. In the stator for dynamo-electric machine of which rotor is disposed inside the stator, a stator core 11 comprises: an inside ring core 9 formed annularly by laminating plate-type magnetic members in which a plurality of teeth are provided on one side of a yoke portion, disposing coils 8 in slots each formed between the teeth, bending the plate-type magnetic members so that the coils 8 are located inside, and bringing two end faces into contact with each other; and an outside ring core 10, being made of magnetic members and formed cylindrical in shape, which is fitted on outside of the inside ring 9 and holds the inside ring core 9.

摘要翻译： 本发明提供一种能够防止效率劣化的发电机的定子。 在转子配置在定子内部的发电机的定子中，定子芯11包括：内环芯9，其通过层压板状磁性构件而形成，其中多个齿在其一侧设置 将线圈8设置在形成在齿之间的槽中，弯曲板状磁性构件，使得线圈8位于内部并使两个端面彼此接触; 以及由磁性部件制成并形成为圆筒状的外圈磁芯10，该外圈磁芯10安装在内圈9的外侧并保持内环芯9。

公开(公告)号：US20050095658A1

公开(公告)日：2005-05-05

申请号：US10502959

申请日：2003-01-30

申请人： Hiroshi Matsui ,  Motoko Ohta

发明人： Hiroshi Matsui ,  Motoko Ohta

IPC分类号： C12Q1/60

CPC分类号： C12Q1/60

摘要： A method for specifically quantifying HDL cholesterol in which cholesterol in lipoproteins other than HDL is erased in the first step, and HDL cholesterol is specifically quantified in the second step, by which accurate values can be obtained even in measurements of abnormal samples such as disorder of lipid metabolism and lipoprotein abnormality, is disclosed. The method for quantifying cholesterol in high density lipoprotein according to the present invention comprises a first step of erasing cholesterol in lipoproteins other than high density lipoprotein by treating a test sample with cholesterol esterase and cholesterol oxidase in the absence of a surfactant which acts on high density lipoprotein and removing generated hydrogen peroxide; and a second step of adding a surfactant which specifically acts on high density lipoprotein to the product of said first step and quantifying hydrogen peroxide generated from cholesterol in high density lipoprotein by actions of cholesterol esterase and cholesterol oxidase. As the cholesterol oxidase used in the first step, one having a molecular weight of not more than 60 kilodaltons is used.

摘要翻译： 用于特异性定量HDL胆固醇的方法，其中在第一步中擦除除HDL之外的脂蛋白中的胆固醇，并且在第二步中特异性地定量HDL胆固醇，即使在异常样品的测量中也可获得精确的值， 脂质代谢和脂蛋白异常。 根据本发明的用于定量高密度脂蛋白中的胆固醇的方法包括通过在不存在以高密度作用的表面活性剂的情况下用胆固醇酯酶和胆固醇氧化酶处理测试样品来消除除了高密度脂蛋白之外的脂蛋白中的胆固醇的第一步骤 脂蛋白和去除产生的过氧化氢; 以及第二步骤，通过胆固醇酯酶和胆固醇氧化酶的作用，将特异性作用于高密度脂蛋白的表面活性剂加入到所述第一步骤的产物中并定量由高密度脂蛋白中的胆固醇产生的过氧化氢。 作为第一步中使用的胆固醇氧化酶，使用分子量不超过60千道尔顿的那些。

公开(公告)号：US06589963B2

公开(公告)日：2003-07-08

申请号：US10148386

申请日：2002-05-31

申请人： Hiroshi Matsui ,  Hideo Kobayashi ,  Satoru Azukizawa ,  Masayasu Kasai ,  Akihisa Yoshimi ,  Hiroaki Shirahase

发明人： Hiroshi Matsui ,  Hideo Kobayashi ,  Satoru Azukizawa ,  Masayasu Kasai ,  Akihisa Yoshimi ,  Hiroaki Shirahase

IPC分类号： C07D40112

CPC分类号： C07D217/22

摘要： A heterocyclic compound of the formula [I] wherein R1 is hydrogen atom or lower alkyl, R2 is hydrogen atom, alkyl optionally having a substituent and the like, R3 is hydrogen atom, lower alkyl and the like, A is a single bond or >N—R5 wherein R5 is hydrogen atom or lower alkyl, B is lower alkylene, and Y is aryl optionally having a substituent and the like, and a pharmaceutically acceptable salt thereof show a hypoglycemic action, a blood hypolipidemic action, an insulin resistance-improving action and a PPAR activating action, and are useful as a hypoglycemic agent, a hypolipidemic agent, an insulin resistance improver, a therapeutic agent of diabetes, a therapeutic agent of diabetic complication, a glucose tolerance improver, an anti-atherosclerosis agent, an anti-obesity agent, an antiinflammatory agent, an agent for the prophylaxis or treatment of PPAR-mediated disease and an agent for the prophylaxis or treatment of syndrome X.

摘要翻译： 式[I]的杂环化合物，其中R 1为氢原子或低级烷基，R 2为氢原子，任选具有取代基的烷基等，R 3为氢原子，低级烷基等，A为单键或> N-R5其中R5为氢原子或低级烷基，B为低级亚烷基，Y为任选具有取代基的芳基等，其药学上可接受的盐呈低血糖作用，降血脂作用，胰岛素抵抗改善 作用和PPAR活化作用，并且可用作降血糖药，降血脂药，胰岛素抵抗改善剂，糖尿病治疗剂，糖尿病并发症治疗剂，葡萄糖耐量改善剂，抗动脉粥样硬化剂，抗 - - 促肥剂，抗炎剂，预防或治疗PPAR介导的疾病的药剂和用于预防或治疗综合症的药剂。

公开(公告)号：USD466883S1

公开(公告)日：2002-12-10

申请号：US29148915

申请日：2001-10-01

申请人： Hiroshi Matsui ,  Toshio Hotta

设计人： Hiroshi Matsui ,  Toshio Hotta

公开(公告)号：USD466491S1

公开(公告)日：2002-12-03

申请号：US29148879

申请日：2001-10-01

申请人： Hiroshi Matsui ,  Toshio Hotta

设计人： Hiroshi Matsui ,  Toshio Hotta

公开(公告)号：US6163804A

公开(公告)日：2000-12-19

申请号：US110027

申请日：1998-07-02

申请人： Hiroshi Matsui

发明人： Hiroshi Matsui

IPC分类号： G06F12/00 ,  G06F13/00 ,  G06F17/30 ,  G06F15/16

CPC分类号： G06F17/30864

摘要： A collecting process of data which is managed by each server on a network is first started by information collection means. Data collected by the information collection means is stored in an information holding means. Subsequently, the data which is needed by a user is extracted by extraction means. Then, the extracted data is outputted to an output destination. In one embodiment, data under a point serving as the root is collected while repeating processes. Such that data at the point serving as a certain root is collected on the basis of access setting information; a link destination is extracted from the collected data and data on the extracted link is further collected. In another embodiment, the data type held in the information holding means is analyzed, then is compared with the data type required by the user by the extraction means. Thus, the data is extracted by extraction means in accordance with the result of the comparison.

摘要翻译： 由网络上的每个服务器管理的数据的收集处理首先由信息收集装置启动。 由信息收集装置收集的数据被存储在信息保存装置中。 随后，提取装置提取用户需要的数据。 然后，将提取的数据输出到输出目的地。 在一个实施例中，在重复处理的同时收集用作根的点下的数据。 使得基于访问设置信息收集用作某个根的点的数据; 从收集的数据中提取链接目的地，进一步收集提取的链接上的数据。 在另一个实施例中，分析保存在信息保存装置中的数据类型，然后与提取装置所要求的数据类型进行比较。 因此，根据比较的结果，提取装置提取数据。

公开(公告)号：US6049047A

公开(公告)日：2000-04-11

申请号：US833209

申请日：1997-04-14

申请人： Takahiro Miyashima ,  Koji Tamano ,  Hiroshi Matsui

发明人： Takahiro Miyashima ,  Koji Tamano ,  Hiroshi Matsui

IPC分类号： H01H1/26 ,  H01H1/58 ,  H01H9/02 ,  H01H11/04 ,  H01H11/06 ,  H01H13/10 ,  H01H1/02

CPC分类号： H01H13/10 ,  H01H1/58 ,  H01H11/04 ,  H01H11/06

摘要： To present an electronic component including a contact integrated type terminal having a terminal portion with excellent mechanical strength and solderability and a contact portion with excellent contact characteristic. It comprises a contact integrated type terminal made of metal having a contact portion formed at one end and a terminal portion formed at other end, a case fixing the contact integrated type terminal, a movable contact placed in the case so as to cover the contact portion, and an operation member for operating the movable contact. The contact integrated type terminal includes a plated layer having solderability and conductivity at least on one side thereof, the terminal portion has a folded and overlaid shape so that the plated layer comes to the outside surface, the terminal portion can be soldered to a wiring board, the contact portion has the plated layer installed at the same side as the one side, and the movable portion contacts with the contact portion by operating the operation member so as to conduct with each other electrically.

摘要翻译： 提供一种电子部件，其包括具有优异机械强度和可焊性的端子部分的接触式集成型端子和具有优异接触特性的接触部分。 它包括一个由金属构成的接触一体型端子，其一端形成有一个接触部分，另一端形成一个端子部分，一个固定该接触集成型端子的壳体，一个放置在壳体中以便覆盖接触部分 以及用于操作可动触头的操作构件。 触点一体型端子包括至少在其一侧具有可焊接性和导电性的镀层，端子部分具有折叠和重叠的形状，使得镀层到达外表面，端子部分可以焊接到布线板 接触部分具有与一侧安装在同一侧的电镀层，并且可动部分通过操作操作部件而与接触部分接触以便​​彼此导电。