公开(公告)号：US11317860B1

公开(公告)日：2022-05-03

申请号：US15225310

申请日：2016-08-01

申请人： Fonar Corporation

发明人： Raymond V. Damadian

IPC分类号： A61B5/00 ,  A61B5/055

摘要： A method and system for assessing the effectiveness of a treatment regimen. In a preferred embodiment, baseline magnetic resonance imaging signals of a diseased portion of a subject's anatomy are acquired and image slices associated with diseased tissue or a selected region of interest are identified. The identified image slices are then stored and used in acquiring subsequent magnetic resonance imaging signals. The baseline and subsequently acquired magnetic resonance imaging signals are then processed to determine changes in location, size or other factors that provide an indication of whether treatment is effective. In another aspect, baseline and subsequent magnetic resonance parameters are also acquired and compared as part of determining the effective of treatment.

公开(公告)号：US09709648B1

公开(公告)日：2017-07-18

申请号：US14203389

申请日：2014-03-10

申请人： Fonar Corporation

发明人： Raymond V. Damadian

IPC分类号： G01R33/48

CPC分类号： G01R33/5608 ,  G01R33/3415 ,  G01R33/3635 ,  G01R33/48 ,  G01R33/4835

摘要： The present disclosure is directed to an apparatus for imaging a subject using MR imaging, and a method of exciting nuclei of the subject within an imaging plane using one or more transmitter circuits tuned to a first transmission frequency, sampling MR signals generated from the nuclei at the same time using one or more receiver circuits each receiver circuit having a bandwidth less than 500 kHz, and generating a MR image based on the sampled MR signals. The speed of MR imaging may be increased by providing multiple pairs of transmitter and receiver circuits to operate simultaneously on an imaging plane and/or by streamlining downstream signal processing using multiple phase detectors tuned to detect frequencies associated with particular phase shifts.

公开(公告)号：US09575152B1

公开(公告)日：2017-02-21

申请号：US14203451

申请日：2014-03-10

申请人： Fonar Corporation

发明人： Raymond V. Damadian

IPC分类号： G01R33/565

CPC分类号： G01R33/5659 ,  G01R33/307 ,  G01R33/36 ,  G01R33/4838

摘要： An MRI apparatus employs a magnet for establishing a B0 field, one or more imaging radiofrequency coils for creating a B1 field, and one or more nulling radiofrequency coils. The RF energy emitted by the nulling radiofrequency coils may be configured such that it disrupts the nuclear magnetic resonance signals emitted by nuclei excited by the B1 field. In addition, the nulling radiofrequency coils may be calibrated to be 180° out of phase such that the RF energy emitted by a pair of nulling radiofrequency coils is cancelled at a location between them.

摘要翻译： MRI装置使用用于建立B0场的磁体，用于产生B1场的一个或多个成像射频线圈和一个或多个归零射频线圈。 归零射频线圈发射的RF能量可以被配置为使得其破坏由B1场激发的核发射的核磁共振信号。 此外，归零射频线圈可以被校准为相位为180°，使得由一对归零射频线圈发射的RF能量在它们之间的位置被取消。

公开(公告)号：US20160051187A1

公开(公告)日：2016-02-25

申请号：US11558433

申请日：2006-11-09

申请人： Raymond V. Damadian

发明人： Raymond V. Damadian

IPC分类号： A61B5/055 ,  G01R33/3815 ,  G01R33/30 ,  G01R33/28 ,  A61M25/01 ,  A61B19/00

CPC分类号： A61B5/4848 ,  A61B5/0555 ,  A61B2505/05 ,  A61B2560/0406 ,  A61B2576/023 ,  A61B2576/026 ,  A61M25/0152 ,  G01R33/288 ,  G01R33/3806 ,  G01R33/3815

摘要： An open MRI methodology and system that allows dynamic viewing and access to a patient. In intraoperative MRI, the MRI apparatus is configured in the shape of a typical operating room, with full 360° access to the patient. The MRI apparatus encompasses the entire operating room with magnets located on or near the ceiling and floor of the operating room. The remainder of the MRI apparatus, including the control computer, and imaging monitor, may be located outside of the MRI operating room, in order to keep the operating room free of unnecessary equipment, or located inside of the MRI operating room, as desired for operability of the MRI. The patient is placed over the magnet in the floor, the only fixed location in the operating room. The operating room may contain typical operating equipment, as needed, such as cardiopulmonary bypass units, surgical navigation systems, endoscopy systems, and anesthesia carts.

摘要翻译： 开放的MRI方法和系统，允许动态观察和访问病人。 在术中MRI中，MRI装置被配置为典型手术室的形状，具有与患者完全360°的通路。 MRI装置包括位于手术室的天花板和地板上或附近的磁体的整个手术室。 包括控制计算机和成像监视器的MRI装置的其余部分可以位于MRI手术室的外部，以便保持手术室没有不必要的设备，或者位于MRI手术室内，如 MRI的可操作性。 患者被放置在地板上的磁铁上，手术室中唯一固定的位置。 操作室可以根据需要包含典型的操作设备，例如心肺旁路装置，手术导航系统，内窥镜检查系统和麻醉车。

公开(公告)号：US09244140B1

公开(公告)日：2016-01-26

申请号：US14450751

申请日：2014-08-04

申请人： FONAR Corporation

发明人： Raymond V. Damadian ,  Gordon T. Danby ,  Hank Hsieh ,  John W. Jackson ,  Mark Gelbien ,  William H. Wahl ,  Charles A. Green

IPC分类号： G01V3/00 ,  G01R33/3875 ,  G01R33/38 ,  G01R33/3815 ,  G01R35/00 ,  G01R33/30

CPC分类号： G01R33/3804 ,  G01R33/307 ,  G01R33/3802 ,  G01R33/3806 ,  G01R33/3815 ,  G01R33/387 ,  G01R33/3873 ,  G01R33/3875 ,  G01R33/421 ,  G01R33/58 ,  G01R35/005 ,  H01F6/04 ,  H01F6/06

摘要： A magnetic resonance imaging configuration, apparatus and method to straighten and otherwise homogenize the field lines in the imaging portion, creating improved image quality. Through use of calibrated corrective coils, magnetic field lines can be manipulated to improve uniformity and image quality. Additionally, when the apparatus is composed of non-ferromagnetic materials, field strengths can be increased to overcome limitations of Iron-based systems such as by use of superconductivity. A patient positioning apparatus allows multi-positioning of a patient within the calibrated and more uniform magnetic field lines.

摘要翻译： 用于使成像部分中的场线拉直或以其它方式均匀化的磁共振成像配置，装置和方法，产生改善的图像质量。 通过使用校准的校正线圈，可以操纵磁场线以提高均匀性和图像质量。 此外，当设备由非铁磁材料组成时，可以增加场强以克服铁基系统的限制，例如通过使用超导性。 患者定位装置允许患者在校准的和更均匀的磁场线中的多位置定位。

公开(公告)号：US08190234B2

公开(公告)日：2012-05-29

申请号：US11172519

申请日：2005-06-30

申请人： Charles A. Green ,  Mark Gelbien ,  John Greenhalgh

发明人： Charles A. Green ,  Mark Gelbien ,  John Greenhalgh

IPC分类号： A61B5/00

CPC分类号： G01R33/3806 ,  A61B5/0555

摘要： A magnetic resonance imaging system having a patient support arranged for pivoting movement about a pivot axis and linear or sliding motion along a support axis transverse to the pivot axis is provided with a device for measuring the location of a patient feature to be imaged. The measured location is used to define coordinates for positioning the patient support. These coordinates desirably are used to automatically move the patient support from a loading position to an imaging position where the feature will be properly aligned with the field axis of the imaging magnet. The system simplifies patient positioning.

摘要翻译： 磁共振成像系统具有布置成围绕枢转轴线枢转运动的患者支架以及沿枢转轴线的支撑轴线的线性或滑动运动，该装置设置有用于测量要成像的患者特征位置的装置。 测量位置用于定义用于定位患者支架的坐标。 理想地，这些坐标用于将患者支撑件从装载位置自动移动到成像位置，其中特征将与成像磁体的场轴正确对准。 该系统简化了患者定位。

公开(公告)号：US08134364B1

公开(公告)日：2012-03-13

申请号：US12799548

申请日：2010-04-27

申请人： Thomas Datzikas

发明人： Thomas Datzikas

IPC分类号： G01V3/00

CPC分类号： G01R33/4833

摘要： A method and apparatus to increase the effectiveness of a Magnetic Resonance Imaging (MRI) device by increasing the signal-to-noise ratio, allowing thinner slice thicknesses, and allowing more contiguous slices. In an MRI device, a patient is subjected to a constant magnetic field, and the RF pulses are used to excite the atoms in the body of the patient. The atoms release a corresponding RF signal when the atoms relax, which can be measured and mapped into a visual display. The RF pulses used to excite the atoms in the body of the patient use a modified Bessel function. The Bessel function having an approximately rectangular waveform in the frequency domain increases the signal-to-noise ratio, allows thinner slice thicknesses, and allows more contiguous slices, resulting in a better MR image and a more efficient MRI apparatus.

摘要翻译： 通过增加信噪比来增加磁共振成像（MRI）装置的有效性的方法和装置，允许更薄的切片厚度，并允许更连续的切片。 在MRI装置中，患者受到恒定的磁场，并且RF脉冲用于激发患者体内的原子。 当原子松弛时，原子释放相应的RF信号，这可以被测量并映射到视觉显示中。 用于激发患者体内的原子的RF脉冲使用改进的贝塞尔函数。 在频域中具有近似矩形波形的贝塞尔函数增加了信噪比，允许更薄的切片厚度，并且允许更连续的切片，导致更好的MR图像和更有效的MRI装置。

公开(公告)号：US20110009731A1

公开(公告)日：2011-01-13

申请号：US12832623

申请日：2010-07-08

申请人： Raymond V. Damadian ,  Ki-Cheung Chu

发明人： Raymond V. Damadian ,  Ki-Cheung Chu

IPC分类号： A61B5/055

CPC分类号： A61B5/055 ,  A61B5/08 ,  A61B5/416

摘要： Vasculature or parenchyma is imaged using upright MRI techniques, on patients who may have conditions such as congestive heart failure, or otherwise be healthy. When an individual is horizontal, venous drainage is minimized, causing the vessels to remain engorged, also referred to herein as vascular congestion. Vascular congestion results in an enlarging of the vessels and surrounding tissue causing the vessels to be more visible on MRIs. The decrease in vascular visibility in upright subjects is in part, due to an increase in venous drainage. Patients suffering from coronary and/or pulmonary deficiencies (e.g. CHF) experience decreased rates and degrees of venous drainage. In one embodiment, the present invention uses upright imaging to visualize these enlarged vessels.

摘要翻译： 使用垂直MRI技术对可能患有充血性心力衰竭或其他方式健康的病人的血管或实质进行成像。 当个体是水平的时，静脉引流最小化，导致血管保持凝血，这里也称为血管充血。 血管充血导致血管和周围组织的扩大，导致血管在MRI上更可见。 直立受试者的血管能见度的下降部分是由于静脉引流的增加。 患有冠状动脉和/或肺部缺血（例如CHF）的患者的经历降低了静脉引流的发生率和程度。 在一个实施例中，本发明使用直立成像来使这些扩大的血管可视化。

公开(公告)号：US07525312B2

公开(公告)日：2009-04-28

申请号：US11726700

申请日：2007-03-21

申请人： Charles A. Green ,  Arto Cinoglu ,  William H. Wahl

发明人： Charles A. Green ,  Arto Cinoglu ,  William H. Wahl

IPC分类号： G01V3/00

CPC分类号： A61B5/0555 ,  A61B34/20 ,  A61B2034/2072 ,  A61B2090/374 ,  G01R33/283 ,  G01R33/307 ,  G01R33/34007 ,  G01R33/34084 ,  G01R33/341 ,  G01R33/3806

摘要： A system and method for magnetic resonance imaging assisted surgery. The system includes an antenna support assembly and an antenna that are used to acquire real time images of the surgical site that may be used by a surgeon to more accurately perform the surgical procedure. The method comprises acquiring real time images of the surgical site and feeding back the images to a surgeon performing the surgical procedure.

摘要翻译： 磁共振成像辅助手术的系统和方法。 该系统包括天线支撑组件和天线，其用于获取手术部位的实时图像，该实时图像可由外科医生使用以更准确地执行外科手术。 该方法包括获取手术部位的实时图像并将图像反馈给执行外科手术的外科医生。

公开(公告)号：US07432707B1

公开(公告)日：2008-10-07

申请号：US11656562

申请日：2007-01-23

申请人： Michael Boitano

发明人： Michael Boitano

IPC分类号： G01V3/00

CPC分类号： G01R33/56 ,  G01R33/5608 ,  G06T5/009 ,  G06T5/40 ,  G06T2207/10088 ,  G06T2207/30004

摘要： The present invention provides a method and apparatus to enhance the image contrast of a Magnetic Resonance Imaging (MRI) device while simultaneously compensating for image inhomogeneity, regardless of the source. The method makes no assumptions as to the source of the inhomogeneities, e.g., physical coil characteristics or patient placement. In the method, the error between the histogram of the spatially-weighted original image and a specified histogram is minimized. The specified histogram may be selected to increase tissue contrast generally or to accentuate a particular tissue class. The weighting is achieved by two-dimensional interpolation of a sparse grid of control points overlaying the image. The sparse grid is used rather than a dense one to compensate for the slowly varying image non-uniformity. Also, sparseness reduces the computational complexity as the final weight set involves the solution of simultaneous linear equations whose number is the size of the chosen grid.

摘要翻译： 本发明提供一种用于增强磁共振成像（MRI）装置的图像对比度的方法和装置，同时补偿图像不均匀性，而不管源。 该方法不对不均匀性的来源（例如物理线圈特征或患者放置）做出假设。 在该方法中，空间加权的原始图像的直方图与指定的直方图之间的误差被最小化。 可以选择指定的直方图以一般地增加组织对比度或强调特定组织分类。 通过覆盖图像的控制点的稀疏网格的二维插值来实现加权。 使用稀疏网格而不是密集网格来补偿缓慢变化的图像不均匀性。 此外，稀疏性降低了计算复杂度，因为最终权重集涉及数字是所选网格的大小的联立线性方程组的解。