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    Nasal adapter for the base of the nose
    2.
    发明申请
    Nasal adapter for the base of the nose 审中-公开
    鼻子适配器为鼻子的基部

    公开(公告)号：US20070131230A1

    公开(公告)日：2007-06-14

    申请号：US10570725

    申请日：2004-09-07

    申请人： Marc Giroux

    发明人： Marc Giroux

    IPC分类号： A62B18/08 ,  A62B18/02

    CPC分类号： A61M15/00 ,  A61M15/08

    摘要： A novel nasal adapter is provided that conforms to, and seals with the base (underside) of a nose. Upward pressure exerted against the inventive nasal adapter compressibly conforms an adapter lip to seal with the underside of the nose. The nasal adapter provides for the comfortable, discreet, and effective transmission of deliverable flow (e.g., fluid, gas, airborne particles and medicament, etc.) to the nasal chambers with minimal leakage. In preferred embodiments, the nasal adapter is formed of a single molded piece made of flexible material and can be made in various sizes to adaptably conform to a broad range of nose sizes, and conformations. Particularly preferred embodiments comprise dual delivery channels with dual outflow apertures that are in communication with at least one lip that is proportioned and disposed to provide for separate delivery channels to each nostril.

    摘要翻译： 提供了一种新颖的鼻部适配器，其与鼻子的底部（底面）一致并且密封。 施加在本发明鼻适配器上的向上压力可压缩地使适配器唇缘与鼻子的下侧密封。 鼻适配器提供了以最小的渗漏方式将输送流（例如，流体，气体，空气传播的颗粒和药物等）舒适，谨慎和有效地传递到鼻腔。 在优选实施例中，鼻适配器由柔性材料制成的单个模制件形成，并且可以制成各种尺寸以适应于宽范围的鼻子尺寸和构造。 特别优选的实施方案包括具有双重流出孔的双递送通道，其与至少一个比例和设置的唇缘连通，以提供到每个鼻孔的分开的递送通道。

    Aerosol generating and delivery device
    4.
    发明授权
    Aerosol generating and delivery device 有权

    公开(公告)号：US10105501B2

    公开(公告)日：2018-10-23

    申请号：US14286692

    申请日：2014-05-23

    申请人： Kurve Technology, Inc.

    发明人： Marc Giroux ,  William A. DeGroodt ,  Joseph R. Pearce ,  Robert W. Kamp ,  Finn O. Rinne ,  Paul C. Leung

    IPC分类号： A61M11/00 ,  A61M11/02 ,  B05B7/08 ,  A61M15/00 ,  A61M15/08 ,  A61M35/00 ,  B05B7/00

    摘要： Particular aspects provide novel atomizers for generating particles over a broad range of MMAD size distributions, the eliminating the requirement for an impaction baffle in generating the desired particle sizes. In particular aspects, the atomization means communicates with a remote particle filter member configured and positioned to provide for particle size filtering. In additional aspects, the atomization means communicates with a particle dispersion chamber suitable to impart a desired particle flow pattern to particles within and exiting the dispersion chamber. In further aspects, the atomization means communicates with a nasal, ocular, oral or ‘vicinity’ adapter. The novel devices provide for targeted (e.g., nasal, ocular, oral, local vicinity), systemic, and/or topical delivery of an atomized liquid (e.g., via the nasal cavity, olfactory region, and mouth). Further exemplary aspects relate to aerosolization and delivery of perfume, fragrance, essential oil or cosmeceutical agents and the like.

    AEROSOL GENERATING AND DELIVERY DEVICE
    8.
    发明申请
    AEROSOL GENERATING AND DELIVERY DEVICE 有权
    航空发电和输送装置

    公开(公告)号：US20120018525A1

    公开(公告)日：2012-01-26

    申请号：US13034569

    申请日：2011-02-24

    申请人： Marc Giroux ,  William A. DeGroodt ,  Joseph R. Pearce ,  Robert W. Kamp ,  Finn O. Rinne ,  Paul C. Leung

    发明人： Marc Giroux ,  William A. DeGroodt ,  Joseph R. Pearce ,  Robert W. Kamp ,  Finn O. Rinne ,  Paul C. Leung

    IPC分类号： B05B7/24

    CPC分类号： A61M11/02 ,  A61M15/0021 ,  A61M15/009 ,  A61M15/08 ,  A61M35/003 ,  B05B7/0012 ,  B05B7/0869

    摘要： Particular aspects provide novel atomizers for generating particles over a broad range of MMAD size distributions, the eliminating the requirement for an impaction baffle in generating the desired particle sizes. In particular aspects, the atomization means communicates with a remote particle filter member configured and positioned to provide for particle size filtering. In additional aspects, the atomization means communicates with a particle dispersion chamber suitable to impart a desired particle flow pattern to particles within and exiting the dispersion chamber. In further aspects, the atomization means communicates with a nasal, ocular, oral or ‘vicinity’ adapter. The novel devices provide for targeted (e.g., nasal, ocular, oral, local vicinity), systemic, and/or topical delivery of an atomized liquid (e.g., via the nasal cavity, olfactory region, and mouth). Further exemplary aspects relate to aerosolization and delivery of perfume, fragrance, essential oil or cosmeceutical agents and the like.

    摘要翻译： 具体方面提供了用于在宽范围的MMAD尺寸分布上产生颗粒的新型雾化器，从而消除了在产生所需颗粒尺寸时对冲击挡板的要求。 在特定方面，雾化装置与配置和定位以提供粒度过滤的远程颗粒过滤器部件通信。 在另外的方面，雾化装置与适合于赋予分散室内和离开分散室的颗粒所需的颗粒流动图案的颗粒分散室连通。 在另外的方面，雾化装置与鼻，眼，口或“附近”适配器连通。 新颖的装置提供雾化液体（例如经鼻腔，嗅觉区域和口腔）的靶向（例如鼻，眼，口服，局部附近），全身和/或局部递送。 另外的示例性方面涉及香料，香料，精油或药妆剂等的雾化和输送。

    Integrated nebulizer and particle dispersion chamber for nasal delivery of medicament to deep nasal cavity and paranasal sinuses
    10.
    发明申请
    Integrated nebulizer and particle dispersion chamber for nasal delivery of medicament to deep nasal cavity and paranasal sinuses 有权
    集成雾化器和颗粒分散室，用于鼻腔输送药物到深鼻腔和鼻旁窦

    公开(公告)号：US20070131224A1

    公开(公告)日：2007-06-14

    申请号：US10570724

    申请日：2004-09-03

    申请人： Marc Giroux

    发明人： Marc Giroux

    IPC分类号： A61M11/00

    CPC分类号： A61M15/08 ,  A61M2206/14

    摘要： Particular aspects provide a novel integrated nebulizer and particle dispersion chamber (12), and novel methods of using same. Preferably, the particle dispersion chamber (12) provides for delivery of a vortical flow of nebulized particles to the notrils. The inventive integrated nebulizer, delivery methods and breathing techniques allow for delivering medicament into the deep nasal cavity and paranasal sinuses of a user. Significantly, the inventive devices and methods allow for systemic and topical delivery of medicaments via the membranes of the nasal cavity and paranasal sinuses. Additional preferred embodiments provide complementary cartridge docking system that allows for user-specific nebulized drug delivery.

    摘要翻译： 具体方面提供了一种新型的一体化雾化器和颗粒分散室（12），以及使用它的新颖方法。 优选地，颗粒分散室（12）提供将雾化颗粒的涡旋流输送到该清洁体。 本发明的一体化雾化器，递送方法和呼吸技术允许将药物输送到使用者的深鼻腔和鼻旁窦。 重要的是，本发明的装置和方法允许通过鼻腔和鼻旁窦的膜全身和局部递送药物。 附加的优选实施例提供允许用户特异性雾化药物递送的补充盒对接系统。