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公开(公告)号：US09873731B2
公开(公告)日：2018-01-23
申请号：US14853696
申请日：2015-09-14
摘要： This invention relates to the administration of an animal immunoglobulin source to mammals such as dairy cattle to improve milk production without negatively affecting reproductive parameters.
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2.发明申请METHODS AND COMPOSITIONS OF TREATMENT FOR MODULATING THE IMMUNE SYSTEM OF ANIMALS 审中-公开用于调节动物免疫系统的方法和组合物公开(公告)号：US20100215667A1
公开(公告)日：2010-08-26
申请号：US12723440
申请日：2010-03-12
申请人： Joy M. Campbell , Ronald E. Strohbehn , Eric M. Weaver , Barton S. Borg , Louis E. Russell , Francisco Javier Polo Pozo , John D. Arthington , James D. Quigley, III
发明人： Joy M. Campbell , Ronald E. Strohbehn , Eric M. Weaver , Barton S. Borg , Louis E. Russell , Francisco Javier Polo Pozo , John D. Arthington , James D. Quigley, III
IPC分类号： A61K39/42 , A61K39/395 , A61P19/02 , A61P3/10 , A61P27/02 , A61P11/06 , A61P7/00 , A61P25/00
CPC分类号： A61K39/15 , A23K10/00 , A61K35/16 , A61K39/12 , A61K39/39 , A61K2039/505 , A61K2039/542 , A61K2039/552 , C07K16/02 , C07K16/04 , C07K16/06 , C07K16/065 , C12N2720/12334 , C12N2770/10011 , C12N2770/10034
摘要： Methods and compositions are disclosed for the dietary modulation of the immune system and gut microbial response in animals. Applicant has identified that oral administration of a supplemental spray dried plasma purified from animal serum can modulate serum IgG levels for treatment in such things as diminished immune capacity, intestinal microbial balance, autoimmune disorders, potentiation of vaccination protocols, and improvement of overall health and weight gain in animals, including humans.
摘要翻译： 公开了用于免疫系统的饮食调节和动物肠内微生物反应的方法和组合物。 申请人已经确定，从动物血清中纯化的补充喷雾干燥血浆的口服给药可以调节血清IgG水平以进行治疗，例如免疫能力降低，肠微生物平衡，自身免疫疾病，增强疫苗接种方案以及提高整体健康和体重 在动物，包括人类的增益。
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3.发明授权公开(公告)号：US07244427B2
公开(公告)日：2007-07-17
申请号：US09772603
申请日：2001-01-30
IPC分类号： A61K39/395 , A61K38/01 , C07K16/00 , C07K16/06
CPC分类号： C07K16/00 , A61K2039/505 , C07K16/065 , C07K2317/10
摘要： A new protein derived from acid hydrolyzed IgG concentrate which has a molecular weight of about 55,000, and is activated by heat within the defined narrow temperature range provides resulting product that has a protective mechanism for bacterial and viral invasion of living cells.
摘要翻译： 衍生自酸水解IgG浓缩物的新蛋白质，其分子量为约55,000，并且在限定的窄温度范围内通过热活化，提供了产生具有细菌和病毒侵入活细胞的保护机制的产物。
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公开(公告)号：US20030223985A1
公开(公告)日：2003-12-04
申请号：US10157449
申请日：2002-05-29
IPC分类号： A61K039/395
CPC分类号： A61K35/16 , A61K38/1709 , A61K2039/505 , A61K2039/542 , A61K2039/545 , C07K16/06
摘要： A globulin protein composition is described. The globulin concentrate is internally administered to animals including humans through food or water, or through conventional pharmaceutical dosage forms. The composition is effective in lowering blood cholesterol and phospholipids.
摘要翻译： 描述了球蛋白蛋白质组合物。 球蛋白浓缩物通过食物或水，或通过常规药物剂型在内部施用于包括人的动物。 该组合物有效降低血液中的胆固醇和磷脂。
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5.发明申请METHODS AND COMPOSITIONS FOR TREATING RESPIRATORY DISEASE-CHALLENGED ANIMALS 审中-公开用于治疗呼吸道疾病动物的方法和组合物公开(公告)号：US20120148570A1
公开(公告)日：2012-06-14
申请号：US13402291
申请日：2012-02-22
申请人： Joy M. Campbell , Ronald E. Strohbehn , Eric M. Weaver , Barton S. Borg , Louis E. Russell , Francisco Javier Polo Pozo , John D. Arthington , James D. Quigley, III
发明人： Joy M. Campbell , Ronald E. Strohbehn , Eric M. Weaver , Barton S. Borg , Louis E. Russell , Francisco Javier Polo Pozo , John D. Arthington , James D. Quigley, III
IPC分类号： A61K39/395 , A61P31/16 , A61P31/04 , A61P11/00
CPC分类号： C07K14/005 , A23K10/20 , A23K10/24 , A23K50/30 , A23K50/75 , A61K35/16 , A61K35/20 , A61K39/12 , A61K39/15 , A61K39/39 , A61K2039/505 , A61K2039/542 , A61K2039/552 , A61K2039/55516 , C07K16/02 , C07K16/04 , C07K16/06 , C07K16/065 , C07K2317/77 , C12N2720/12322 , C12N2720/12334 , C12N2770/10022 , C12N2770/10034
摘要： Methods and compostions are disclosed for modulating the immune system of animals. Applicant has identified that oral administration of immunoglobulins purified from animal blood can modulate the immune system for treatment of respiratory disease challenges, as well as modulate serum IgG levels for treatment of immune dysfunction disorders, potentiation of vaccination protocols, and improvement of overall health and weight gain in animals, including humans.
摘要翻译： 公开了用于调节动物免疫系统的方法和组合物。 申请人已经确定，从动物血液中纯化的免疫球蛋白的口服给药可以调节用于治疗呼吸系统疾病挑战的免疫系统，以及调节用于治疗免疫功能障碍的血清IgG水平，增强疫苗接种方案以及提高整体健康和体重 在动物，包括人类的增益。
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公开(公告)号：US20030104034A1
公开(公告)日：2003-06-05
申请号：US10074896
申请日：2002-02-13
IPC分类号： A61K047/00
CPC分类号： A23K50/75 , A23K10/24 , A23K20/147
摘要： The present invention relates to a method of increasing the live weight of poultry through the administration of a plasma product to the poultry through the animals' feed and/or water. The product is effective in increasing the live weight of poultry. The product is also surprisingly effective in increasing the yield of white meat to the detriment of dark meat.
摘要翻译： 本发明涉及一种通过动物的饲料和/或水通过向家禽施用血浆产品来增加家禽的活重的方法。 该产品有效提高家禽的活重。 该产品在提高白肉的产量方面也令人惊奇地有效，不利于黑肉。
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公开(公告)号：US07258870B2
公开(公告)日：2007-08-21
申请号：US10074896
申请日：2002-02-13
CPC分类号： A23K50/75 , A23K10/24 , A23K20/147
摘要： The present invention relates to a method of increasing the live weight of poultry through the administration of a plasma product to the poultry through the animals' feed and/or water. The product is effective in increasing the live weight of poultry. The product is also surprisingly effective in increasing the yield of white meat to the detriment of dark meat.
摘要翻译： 本发明涉及一种通过动物的饲料和/或水通过向家禽施用血浆产品来增加家禽的活重的方法。 该产品有效提高家禽的活重。 该产品在提高白肉的产量方面也令人惊奇地有效，不利于黑肉。
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8.发明授权公开(公告)号：US06939954B2
公开(公告)日：2005-09-06
申请号：US09941965
申请日：2001-08-27
CPC分类号： C07K16/065 , A61K2039/505
摘要： A new protein derived from acid hydrolyzed IgG concentrate which has a molecular weight of about 55,000, and is activated by heat within the defined narrow temperature range provides resulting product that has a protective mechanism for bacterial and viral invasion of living cells.
摘要翻译： 衍生自酸水解IgG浓缩物的新蛋白质，其分子量为约55,000，并且在限定的窄温度范围内通过热活化，提供了产生具有细菌和病毒侵入活细胞的保护机制的产物。
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