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8 条记录 (耗时 0.014 秒)

    Treatment of obsessive-compulsive disorders with 5-HT.sub.2 antagonists
    1.
    发明授权
    Treatment of obsessive-compulsive disorders with 5-HT.sub.2 antagonists 失效
    用5-HT2拮抗剂治疗强迫症

    公开(公告)号：US5618824A

    公开(公告)日：1997-04-08

    申请号：US209084

    申请日：1994-03-09

    申请人： Christopher J. Schmidt ,  John H. Kehne ,  Robert A. Padich

    发明人： Christopher J. Schmidt ,  John H. Kehne ,  Robert A. Padich

    IPC分类号： C07D211/22 ,  A61K31/445 ,  A61K31/451 ,  A61K45/00 ,  A61P43/00

    CPC分类号： A61K31/445

    摘要： The present invention is directed to 5-HT.sub.2 antagonists and their use as agents in the treatment of obsessive-compulsive disorders (OCD). The invention is particularly directed to the compound (+)-.alpha.-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol which is a member of a class of 5-HT.sub.2 antagonists known as N-aralkyl piperidinemethanol derivatives which are potent and selective inhibitors of the binding of serotonin at the 5-HT.sub.2 receptor site.

    摘要翻译： 本发明涉及5-HT2拮抗剂及其作为治疗强迫症（OCD）的药物的用途。 本发明特别涉及作为一类5-HT2拮抗剂的成员的化合物（+） - α-（2,3-二甲氧基苯基）-1- [2-（4-氟苯基）乙基] -4-哌啶甲醇 称为N-芳烷基哌啶甲醇衍生物，其是5-羟色胺在5-HT2受体位点结合的有效和选择性抑制剂。

    Power crimping tool
    3.
    发明授权
    Power crimping tool 失效
    电动压接工具

    公开(公告)号：US07146837B2

    公开(公告)日：2006-12-12

    申请号：US10941378

    申请日：2004-09-15

    申请人： Christopher J. Schmidt

    发明人： Christopher J. Schmidt

    IPC分类号： B23P11/00 ,  B21D39/00

    CPC分类号： E04F13/06 ,  B27F7/025 ,  E04F19/022 ,  E04F2013/063 ,  Y10T29/53709

    摘要： A tool for crimping work pieces to one another is disclosed. The tool is mounted on a power actuator having a reciprocating ram for effecting crimping. The tool includes a body engageable with the workpiece. A movable head is mounted on the body and receives the ram. A jaw is pivotably mounted on the body. A link connects the head to the jaw, which pivots in response to the ram engaging and moving the head. The jaw has a tooth that penetrates the work pieces upon pivoting of the jaw. Penetration of the work pieces by the tooth crimps the pieces to one another. A receiver is mounted on the body to permit its engagement with the actuator by means of an attachment device adapted to a particular actuator. The tool may be removably attachable to the actuator or permanently attached thereto.

    摘要翻译： 公开了一种用于将工件彼此压接的工具。 该工具安装在具有用于实现卷曲的往复式压头的动力执行机构上。 该工具包括可与工件接合的主体。 可移动头安装在主体上并接收冲头。 颚可枢转地安装在身上。 一个连接头将头部连接到颚板上，该颚板响应于该凸块接合和移动头部而枢转。 钳口具有在颚枢转时穿过工件的牙齿。 通过牙齿将工件的穿透将件彼此压紧。 接收器安装在主体上以允许其通过适于特定致动器的附接装置与致动器接合。 工具可以可拆卸地附接到致动器或永久地附接到致动器。