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公开(公告)号:US20240158430A1
公开(公告)日:2024-05-16
申请号:US18281202
申请日:2022-02-25
Applicant: AKITA UNIVERSITY , TOHOKU UNIVERSITY
Inventor: Hiroyuki SHIBATA , Yoshiharu IWABUCHI
IPC: C07H19/056 , A61K31/7056 , A61P35/00
CPC classification number: C07H19/056 , A61K31/7056 , A61P35/00
Abstract: Provided is a new compound or a salt thereof having improved in vivo efficacy and antitumor activity of a curcumin derivative, and an antitumor activator containing the new compound or the salt thereof as an active ingredient. The compound or a salt thereof is represented by the following general formula. R1 to R4 are substituents selected from a hydrogen atom, a C1-4 lower alkyl group, a hydroxy C1-4 lower alkyl group, a C1-4 lower alkoxy C1-4 lower alkyl group, and a C1-4 lower alkoxy C1-4 lower alkoxy C1-4 lower alkyl group, and R1 to R4 may be the same or different. n is 1 to 6. Sugar is a monosaccharide or a disaccharide.
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公开(公告)号:US20240026205A1
公开(公告)日:2024-01-25
申请号:US18255424
申请日:2021-12-03
Applicant: AKITA UNIVERSITY , KANEKA CORPORATION
Inventor: Shigemi NAGANAWA , Ryutaro MUKAI
CPC classification number: C09K8/206 , C09K8/035 , C09K8/032 , E21B21/003 , C09K2208/08
Abstract: The present invention is directed to a drilling fluid containing water, biodegradable fibers, and a thickener. The thickener contains a water-absorbing silicate, and the biodegradable fibers have a fiber length of 5.0 to 50 mm.
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公开(公告)号:US11759755B2
公开(公告)日:2023-09-19
申请号:US17793365
申请日:2021-01-29
Applicant: AKIMOKU IRON WORKS CO., LTD. , AKITA UNIVERSITY
Inventor: Akira Nakagawa , Wataru Sugiyama
IPC: B01F3/04 , B01F23/2373 , B01F25/31 , B01F35/71 , B01F25/313 , B01F23/232 , B01F25/10 , B01F25/00
CPC classification number: B01F23/2373 , B01F23/232 , B01F25/104 , B01F25/311 , B01F25/3133 , B01F35/71805 , B01F2025/9321
Abstract: A fine bubble generator which is an ultrafine bubble generator includes a side wall whose inner face is cylindrical, and closing walls closing both ends of the side wall, respectively, with a gas-liquid discharge port in one of the closing walls, wherein a fluid inlet port is provided closer to the gas-liquid discharge port than is a midpoint between both closing walls, and the fluid inlet port penetrates the side wall in a tangential direction of the inner face of the side wall, wherein a spiral groove is formed in the inner face of side wall, and wherein the spiral groove has an angle of inclination of 1° to 10°.
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公开(公告)号:US20210039339A1
公开(公告)日:2021-02-11
申请号:US16966257
申请日:2019-01-31
Applicant: MITSUBISHI HEAVY INDUSTRIES, LTD. , Akita University
Inventor: Nobuyuki KAMIHARA , Kiyoka TAKAGI , Toshio ABE , Mikio MURAOKA , Toshiyuki TAKAYANAGI , Naomoto ISHIKAWA , Wataru NISHIMURA , Sota KAMO , Tomoharu DENGO , Takashi ISHIDA , Yukihiro YOSHIDA
Abstract: A method for molding a composite material includes a conductive wire-shaped material arrangement step and a magnetic field application step. The conductive wire-shaped material arrangement step is a step for arranging, in a pre-reaction composite material including reinforcing fibers, a plurality of conductive wire-shaped materials along a direction intersecting the reinforcing fibers with intervals wider than intervals of the reinforcing fibers in a plane on which the reinforcing fibers are arranged. The magnetic field application step is a step for applying a magnetic field in a direction intersecting the plane on which the reinforcing fibers are arranged.
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公开(公告)号:US10815369B2
公开(公告)日:2020-10-27
申请号:US16324186
申请日:2017-08-08
Applicant: AKITA UNIVERSITY , DAIKIN INDUSTRIES, LTD.
Inventor: Kazuya Matsumoto , Mitsutoshi Jikei , Sumito Yamakawa , Tadatake Sakurada , Fumihiro Kamiya , Tsuyoshi Noguchi
Abstract: The invention provides a composition capable of providing a molded article that has excellent heat resistance and a small weight change against oxygen plasma exposure and fluorine plasma exposure during a semiconductor manufacturing step. The composition contains a fluorine-containing polymer and a hyperbranched polymer of a cage silsesquioxane with a specific structure.
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公开(公告)号:US20190169415A1
公开(公告)日:2019-06-06
申请号:US16324186
申请日:2017-08-08
Applicant: AKITA UNIVERSITY , DAIKIN INDUSTRIES, LTD.
Inventor: Kazuya MATSUMOTO , Mitsutoshi JIKEI , Sumito YAMAKAWA , Tadatake SAKURADA , Fumihiro KAMIYA , Tsuyoshi NOGUCHI
Abstract: The invention provides a composition capable of providing a molded article that has excellent heat resistance and a small weight change against oxygen plasma exposure and fluorine plasma exposure during a semiconductor manufacturing step. The composition contains a fluorine-containing polymer and a hyperbranched polymer of a cage silsesquioxane with a specific structure.
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公开(公告)号:US09920376B2
公开(公告)日:2018-03-20
申请号:US14749289
申请日:2015-06-24
Inventor: Satoru Motoyama , Masatomo Miura , Junichi Ogawa
IPC: C12Q1/68
CPC classification number: C12Q1/6886 , C12Q2600/112 , C12Q2600/118 , C12Q2600/156 , C12Q2600/158
Abstract: The objective of the present invention is to provide a method and a means of rapidly and reliably detecting lymph node metastasis in cancer or the risk of lymph node metastasis. Specifically, the present invention provides a method and a rapid determination kit for detecting lymph node metastasis in cancer or its risk by identifying a certain genetic polymorphism of the human CRP gene, and it is clinically significant in determining the treatment strategy, because effective prediction/determination can be made regarding lymph node metastasis, which is an important phenomenon in cancer progression.
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公开(公告)号:US20240387892A1
公开(公告)日:2024-11-21
申请号:US18565244
申请日:2022-06-16
Applicant: DOWA ECO SYSTEM CO., LTD. , AKITA UNIVERSITY
Inventor: Tatsuya YODOSE , Ryoei WATANABE , Yoshihiro HONMA , Seiji KUMAGAI
Abstract: There is provided a recycled cathode material precursor, including: a metal element α consisting of at least one of nickel, cobalt and manganese; and a metal element β consisting of at least one of iron, copper and aluminum, wherein a content of the metal element β is 0.5 to 20% by mass in the recycled cathode material precursor.
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公开(公告)号:US20240376047A1
公开(公告)日:2024-11-14
申请号:US18691225
申请日:2022-07-04
Applicant: Akita University , SUMITOMO CHEMICAL COMPANY, LIMITED
Inventor: Atsushi SHIBAYAMA , Manabu YAMADA , Kazutoshi HAGA , Jia ZHAO , Ayumi ASANO
IPC: C07C321/28 , B03D1/012 , B03D1/02
Abstract: Provided are: A collector containing a compound that increases the recovery amount of a target mineral; a flotation method that uses this compound; and a compound that is suitable as a collector. This collector includes a compound represented by the following formula (1). (In formula (1), R1 represents an alkyl group having 1 or more and 18 or less carbon atoms, and X represents NR2R3, SR4, or OR5, and R2-3 each represents hydrogen or an alkyl group having 1 or more and 18 or less carbon atoms, and R4-5 each represent an alkyl group having 1 or more and 18 or less carbon atoms.
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公开(公告)号:US20240118234A1
公开(公告)日:2024-04-11
申请号:US18275906
申请日:2022-02-09
Applicant: MITSUBISHI HEAVY INDUSTRIES, LTD. , Akita University
Inventor: Mikio MURAOKA , Nobuyuki KAMIHARA , Kiyoka TAKAGI , Sota KAMO , Naomoto ISHIKAWA , Hideki HORIZONO , Toshiyuki TAKAYANAGI
IPC: G01N27/24
CPC classification number: G01N27/24
Abstract: A joint portion evaluating method for measuring and evaluating a joint state of a joint portion at which a first joint body and a second joint body are joined together, the joint portion evaluating method including the steps of: acquiring as a reference value a capacitance value of the joint portion in a reference measurement state serving as a reference for measurement conditions; changing a measurement state from the reference measurement state and acquiring as a measured value a capacitance value of the joint portion in a changed measurement state arising after the change of the measurement state; deriving as a measurement evaluation value a value obtained by referencing the measured value with the reference value; and performing an evaluation based on the derived measurement evaluation value.
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