公开(公告)号：US20240353379A1

公开(公告)日：2024-10-24

申请号：US18627829

申请日：2024-04-05

申请人： ARKRAY, Inc.

发明人： Kazuki ISHIKAWA

IPC分类号： G01N30/26 ,  G01N30/02 ,  G01N30/88

CPC分类号： G01N30/26 ,  G01N2030/027 ,  G01N30/88 ,  G01N2030/8822

摘要： A method of treating a measurement flow channel, the method comprising performing a conditioning treatment of causing a conditioning liquid, in which albumin, casein, or skim milk is dissolved, to flow through a measurement flow channel of a liquid chromatography device for analyzing hemoglobin in a specimen before analyzing the hemoglobin.

公开(公告)号：US20240255080A1

公开(公告)日：2024-08-01

申请号：US18425580

申请日：2024-01-29

申请人： ARKRAY, Inc.

发明人： Takao MINAMI

IPC分类号： F16L25/14 ,  F16L25/00 ,  F16L25/12

CPC分类号： F16L25/14 ,  F16L25/0018 ,  F16L25/009 ,  F16L25/12

摘要： In a flow path member joining structure for enabling a liquid to flow by attaching, to a first member having a first flow path, a second member having a second flow path and aligning the first flow path and the second flow path with each other, the first flow path is open toward a first end face of the first member, and an enlarged diameter portion whose inner diameter gradually increases toward the first end face is formed at an end of the first flow path, and the second flow path is open toward a second end face of the second member.

公开(公告)号：US20240201206A1

公开(公告)日：2024-06-20

申请号：US18539696

申请日：2023-12-14

申请人： ARKRAY, Inc.

发明人： Kazuki ISHIKAWA

IPC分类号： G01N33/72 ,  B01D15/36 ,  G01N30/86 ,  G16B40/10 ,  G16B50/30

CPC分类号： G01N33/721 ,  B01D15/362 ,  G01N30/8631 ,  G01N30/8679 ,  G16B40/10 ,  G16B50/30 ,  G01N2030/027

摘要： Provided is a method for estimating a hemoglobin A1c level including acquiring in advance a correlation between a hemoglobin A1c level which is based on the ratio of the peak value of a hemoglobin A1c peak to the total of the peak values related to hemoglobin A and a glycated mutant hemoglobin level which is based on the ratio of the peak value of a glycated mutant hemoglobin peak to the total of the peak values containing mutant hemoglobin and the peak value of the glycated mutant hemoglobin peak containing glycated mutant hemoglobin formed by glycating the mutant hemoglobin, from a chromatogram of a blood specimen that contains the hemoglobin A and the mutant hemoglobin, deriving a glycated mutant hemoglobin level from a chromatogram of a blood specimen, and estimating a hemoglobin A1c level based on the derived glycated mutant hemoglobin level and the correlation.

公开(公告)号：US20240159769A1

公开(公告)日：2024-05-16

申请号：US18383317

申请日：2023-10-24

申请人： ARKRAY, Inc.

发明人： Misaki OGA ,  Atsushi SUGIMOTO

IPC分类号： G01N33/68 ,  B01L3/00 ,  G01N1/34

CPC分类号： G01N33/6827 ,  B01L3/50273 ,  G01N1/34 ,  B01L2200/16 ,  B01L2300/0838 ,  B01L2400/0421 ,  G01N2333/4713 ,  G01N2333/765

摘要： Provided is a sample analysis method, including separating albumin and γ-globulin from a sample containing albumin and γ-globulin, in an alkaline solution by capillary electrophoresis, in which the sample contains a non-surfactant-type sulfobetaine, and the alkaline solution contains a cationic polymer.

公开(公告)号：US20240077450A1

公开(公告)日：2024-03-07

申请号：US18453811

申请日：2023-08-22

申请人： ARKRAY, Inc.

发明人： Gai GO ,  Atsushi MURAKAMI

IPC分类号： G01N33/543

CPC分类号： G01N33/5438

摘要： A measurement system including a sensor and a measurement device including an insertion port for the sensor, wherein the measurement device measures a measurement target component at the sensor and includes plural terminals contacting the sensor, and the terminals slide on a contact surface of the sensor, the contact surface has a first electrode group on a rear end side and a second electrode group on a distal end side, the plural terminals receive static frictional forces from the contact surface and include a first terminal group contacting the first electrode group on a side closer to the insertion port than a side on which a second terminal group contacting the second electrode group, and a sum of static frictional forces that the first terminal group receives from the contact surface is smaller than a sum of static frictional forces that the second terminal group receives from the contact surface.

公开(公告)号：US20240037706A1

公开(公告)日：2024-02-01

申请号：US18225271

申请日：2023-07-24

申请人： ARKRAY, Inc.

发明人： Koji FUJIMOTO

IPC分类号： G06T5/50 ,  G06T3/40 ,  H04N23/667 ,  G01N21/05

CPC分类号： G06T5/50 ,  G06T3/4038 ,  H04N23/667 ,  G01N21/05 ,  G06T2207/20221

摘要： An information processing device includes an acquisition section that is coupled to a camera that continuously images a sample including a material component and flowing through a flow cell in time series and generates a first image of the sample and a second image in which a portion continuous to the first image in time series overlaps a part of the first image, and acquires the first image and the second image generated by the camera, and an image output section that outputs a composite image obtained by combining the first image and the second image.

公开(公告)号：US20230314460A1

公开(公告)日：2023-10-05

申请号：US18126771

申请日：2023-03-27

申请人： ARKRAY, Inc.

发明人： Hajime FUKUMARU ,  Suguru YOSHIDA

IPC分类号： G01N35/10 ,  B01L3/00

CPC分类号： G01N35/1011 ,  B01L3/56

摘要： A method of producing a sample collection apparatus, including steps of: attaching a holding member to a support of a nozzle unit such that, in slits provided with N edges (N≥3), a collection range w of a sample tube is included within a range from a lower-limit position at a distance w/2 from a 1st edge toward an initial-position, to an upper-limit position at a distance w/2 from an Nth edge away from the initial position; loading the sample tube on the holding member; counting the number of pulses with which a pulse motor is driven to move a nozzle to the center of the collection range; identifying the signal corresponding to the last edge recognized by a photo-interrupter before the nozzle reaches the center of the collection range; and storing the number of pulses and the signal corresponding to the last edge in a storage device.

公开(公告)号：US20230305025A1

公开(公告)日：2023-09-28

申请号：US18123477

申请日：2023-03-20

申请人： ARKRAY, Inc.

发明人： Kazuki ISHIKAWA

IPC分类号： G01N33/72 ,  G01N30/86

CPC分类号： G01N33/721 ,  G01N30/8631 ,  G01N2030/027

摘要： A first correlation equation is preliminarily determined from a chromatogram obtained by subjecting, to liquid chromatography, a first blood sample group which is known to contain HbA1c, and whose content ratio of HbF in total hemoglobin is known to be less than a predetermined content ratio, the first correlation equation being a correlation equation between an HbA1c peak value and a composite peak value including an HbA1a peak and an HbA1b peak. A composite peak value obtained by applying, to the first correlation equation, an HbA1c peak value of a chromatogram obtained by subjecting a measurement target blood sample to liquid chromatography is subtracted from a composite peak value including an HbA1a peak and an HbA1b peak in the blood sample, to calculate a modified HbF peak value. The modified HbF peak value is added to an HbF peak value of the blood sample, to correct the HbF peak value.

公开(公告)号：US11619765B2

公开(公告)日：2023-04-04

申请号：US16542961

申请日：2019-08-16

申请人： ARKRAY, Inc.

发明人： Hirohisa Uchida

IPC分类号： G02B1/111 ,  C30B29/54 ,  G02F1/35 ,  G02F1/355

摘要： An optical element includes an optical crystal and an antireflection film coating the surface of the optical crystal. The antireflection film contains an organic compound that includes, as a structural unit, at least one of a compound containing a cyclic structure to which a fluorine atom is bound and a compound containing a cyclic olefin structure.

公开(公告)号：US20230086219A1

公开(公告)日：2023-03-23

申请号：US17940702

申请日：2022-09-08

申请人： ARKRAY, Inc.

发明人： Ayano NAKATANI ,  Takeshi SHIMIZU

IPC分类号： G01N27/327 ,  G01N33/49

摘要： Using a biosensor including a flow path into which blood containing a target is introduced, an upstream electrode pair disposed in the flow path and having a reagent reacting with the target disposed on either of the electrodes, and a downstream electrode pair disposed at a downstream side of the flow path; the method includes a first detection step of detecting a first introduction of blood as far as the upstream electrode pair; a second detection step of detecting a second introduction of blood as far as the downstream electrode pair; a time measurement step of measuring a time difference from the first introduction to the second introduction; and a measurement step of acquiring the value related to the target based on the time difference by using any two electrodes among the upstream and downstream electrode pair after the second introduction is detected.