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公开(公告)号:US12195474B2
公开(公告)日:2025-01-14
申请号:US17568851
申请日:2022-01-05
Applicant: Xinxiang Medical College , Anhui University of Technology
Inventor: Qinghe Gao , Xinya Han , Yongtao Xu , Yingchao Duan , Jieli Lv , Lizhen Fang , Yan Zhang , Jufen Yan , Yingying Li
IPC: C07D487/04
Abstract: A preparation method of zaleplon is provided and belongs to the technical field of pharmaceutical chemistry. The preparation method adopts simple and cheap m-nitrobenzaldehyde and triethylamine as raw materials, and constructs a core structure of zaleplon with high efficiency and high selectivity through a one-pot series reaction without transition metal catalysis, thereby avoiding the formation of isomers, reducing the generation of by-products, increasing the yield of target products and reducing the synthesis cost; and after simple nitro reduction modification, zaleplon is prepared. The method has the advantages of short preparation route, mild reaction conditions and simple operation, so the method is suitable for industrial production.
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公开(公告)号:US12131438B2
公开(公告)日:2024-10-29
申请号:US17668483
申请日:2022-02-10
Inventor: Jie Chen , Huiyao Wan , Zhixiang Huang , Xiaoping Liu , Bocai Wu , Runfan Xia , Zheng Zhou , Jianming Lv , Yun Feng , Wentian Du , Jingqian Yu
IPC: G06T3/40 , G01S13/90 , G06V10/40 , G06V10/764 , G06V10/77 , G06V10/774 , G06V10/94
CPC classification number: G06T3/40 , G01S13/9021 , G06V10/40 , G06V10/764 , G06V10/7715 , G06V10/774 , G06V10/95 , G06V2201/07
Abstract: The present disclosure provides a synthetic aperture radar (SAR) image target detection method. The present disclosure takes the anchor-free target detection algorithm YOLOX as the basic framework, reconstructs the backbone feature extraction network from the lightweight perspective, and replaces the depthwise separable convolution in MobilenetV2 with one ordinary convolution and one depthwise separable convolution. The number of channels in the feature map is reduced by half through the ordinary convolution, features input from the ordinary convolution are further extracted by the depthwise separable convolution, and the convolutional results from the two convolutions are spliced. The present disclosure highlights the unique strong scattering characteristic of the SAR target through the attention enhancement pyramid attention network (CSEMPAN) by integrating channels and spatial attention mechanisms. In view of the multiple scales and strong sparseness of the SAR target, the present disclosure uses an ESPHead.
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3.
公开(公告)号:US20240338570A1
公开(公告)日:2024-10-10
申请号:US18747561
申请日:2024-06-19
Applicant: Anhui University
Inventor: Changyin SUN , Wenzhang LIU , Chaoxu MU , Lu REN , Zhuoran SHI
IPC: G06N3/092
CPC classification number: G06N3/092
Abstract: A deep reinforcement learning (DRL) intelligent decision-making platform based on a unified AI framework includes a parameter configuration module, a general-purpose module, an original environment module, an environment vectorization module, an environments maker, a mathematical utilities module, a model library and a runner. Parameters of a DRL model are selected through the parameter configuration module, and read by the general-purpose module. Based on the read parameters, a representer, a policy module, a learner, and an intelligent agent are called from the model library and created, where necessary function definitions and optimizers are called from the mathematical utilities module. Based on the read parameters, the environment vectorization module is created based on the original environment. The intelligent agent and environments are input into the runner to compute an action output, which executes the action output to realize the intelligent decision making.
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公开(公告)号:US12059467B2
公开(公告)日:2024-08-13
申请号:US18278416
申请日:2022-08-24
Applicant: ANHUI UNIVERSITY
Inventor: Rupei Tang , Guoqing Yan , Xin Wang
IPC: A61K47/22 , A61K31/337 , A61K31/415 , A61K31/4184 , A61K31/445 , A61K38/28 , A61K38/38 , A61K47/34 , C07D317/34
CPC classification number: A61K47/22 , A61K31/337 , A61K31/415 , A61K31/4184 , A61K31/445 , A61K38/28 , A61K38/38 , A61K47/34 , C07D317/34
Abstract: An improved low-toxicity and high-efficiency orthoester mixture pharmaceutical adjuvant, a preparation method thereof, and a topical sustained release drug delivery formulation including the same are provided. The improved low-toxicity and high-efficiency orthoester mixture pharmaceutical adjuvant is obtained by mixing methoxy-free orthoester compounds (classes I and II) in different proportions or mixing an orthoester compound (class I or II) with a biocompatible medical polymer material in different proportions, where an orthoester compound of class I has a chemical formula shown in formula I:
and an orthoester compound of class II has a chemical formula shown in formula II:
The present disclosure has the following beneficial effects: In the present disclosure, the biosafety of the pharmaceutical adjuvant is improved by adjusting a substituent type and a length of an orthoester compound, and the properties of the orthoester mixture pharmaceutical adjuvant do not change before and after the improvement.-
5.
公开(公告)号:US12044584B2
公开(公告)日:2024-07-23
申请号:US17771818
申请日:2021-12-31
Applicant: ANHUI UNIVERSITY
Inventor: Xiaohui Guo , Zhiliang Chen , Pengbin Gui , Siliang Wang , Wei Zeng , Xingang Ren , Lixia Yang , Yaohua Xu , Zhixiang Haung
IPC: G01L1/14
CPC classification number: G01L1/144
Abstract: A high sensitivity flexible three-dimensional force tactile sensor includes a hemispherical contact, wherein the hemispherical contact includes a tray with a groove on the surface and a hemispherical protrusion arranged in the groove. A flexible inverted cone component connected to the lower surface of the hemispherical contact, wherein a plurality of flexible triangular excitation electrode is arranged on the side surface of the flexible inverted cone component. A flexible common electrode surrounding part of the flexible triangular excitation electrode, wherein a first cavity with an opening is opened inside the flexible common electrode, parts of the flexible triangular excitation electrode and the flexible inverted cone component are arranged in the first cavity of the flexible common electrode. The flexible triangular excitation electrode and the flexible inverted cone component have no contact with the inner wall of the first cavity of the flexible common electrode to form an air cavity.
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公开(公告)号:US20240228851A1
公开(公告)日:2024-07-11
申请号:US18200293
申请日:2023-05-22
Applicant: ANHUI UNIVERSITY OF TECHNOLOGY
Inventor: Dong WANG , Sensen DENG , Aiquan JIA , Mengxue LI
IPC: C09K5/04
CPC classification number: C09K5/045 , C09K2205/106 , C09K2205/122 , C09K2205/32
Abstract: Provided is a near-azeotropic refrigerant of a ternary mixture CO2/R41/R170, including the following components by mass percentage: 10% to 64% of CO2, 10% to 47% of R41, and 26% to 52% of R170. The near-azeotropic refrigerant has a low global warming potential (GWP) and a low temperature glide, and can still maintain a near-azeotropic effect at −90° C.
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7.
公开(公告)号:US20240175803A1
公开(公告)日:2024-05-30
申请号:US18432313
申请日:2024-02-05
Applicant: Anhui University of Science and Technology
Inventor: Huawei JIN , Xu WANG , Haowei WANG
CPC classification number: G01N21/1702 , G01N1/14 , G01N33/0027 , G01N2021/1704 , G01N2201/06113 , G01N2201/0636
Abstract: Disclosed is a synchronous detection system for a trace nitrogen-oxygen compound based on photoacoustic spectrometry, including a NOx (Nitrogen Oxide) detection air channel, a dust detection air channel and a double-photoacoustic spectrometry detection mechanism which are mutually connected in parallel; the NOx detection air channel includes a background interference detection air pipe, a NO2 detection air pipe and a NO detection air pipe that are mutually connected in parallel, and a NOx photoacoustic detection cavity; and the dust detection air channel includes a dust detection air pipe and a dust photoacoustic detection cavity communicating with the dust detection air pipe.
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8.
公开(公告)号:US20240170683A1
公开(公告)日:2024-05-23
申请号:US18282791
申请日:2022-07-20
Applicant: ANHUI UNIVERSITY
Inventor: Junzhong WANG
CPC classification number: H01M4/8807 , H01M4/8605 , H01M4/8846 , H01M4/886 , H01M4/96
Abstract: A carbon fiber and graphene compounded high-strength porous material, and a gas diffusion layer and a preparation method therefor are provided. The carbon material integrates respective structures and characteristic advantages of a carbon fiber and graphene, complements each other, and has characteristics such as high mechanical strength (the carbon fiber is not cut off), hierarchical pore gradient distribution, good air permeability, good electric conductivity, good thermal conductivity, light weight, and high stability. The preparation method includes process steps such as graphene preparation, filament split of a carbon fiber bundle by spreading a liquid film, adsorption and anchoring of a filament by means of graphene, graphene coating, and high-temperature treatment. In the preparation process of the carbon-based gas diffusion layer, the carbon fiber is not cut off, the strength of the carbon fiber is kept, and the carbon-based gas diffusion layer is suitable for roll-to-roll batch preparation.
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公开(公告)号:US20240120633A1
公开(公告)日:2024-04-11
申请号:US18539132
申请日:2023-12-13
Applicant: Anhui University
Inventor: Xingang REN , Shengyang WEI , Yali ZHAO , Guoxing SUN , Jiayu RAO , Gang WANG , Kaikun NIU , Xianliang WU , Zhixiang HUANG , Yingsong LI , Yong PENG
CPC classification number: H01P7/00 , H05K1/0236
Abstract: An ultra-wideband electromagnetic band gap (EBG) structure includes multiple EBG units in an array. Each EBG unit includes a power plane, a dielectric substrate and a ground plane from top to bottom. The power plane includes a patch, a coupled complementary split ring resonator (C-CSRR) and a plurality of semi-improved Z-bridge structures. Each edge of the patch is provided with a semi-improved Z-bridge structure. The C-CSRR is provided within a ring formed by the semi-improved Z-bridge structures. The Z-bridge structure includes a first horizontal branch, a first vertical branch, a second horizontal branch and a second vertical branch connected in sequence. The second vertical branch is connected to the patch. First horizontal branches of adjacent EBG units are connected to each other. A circuit board including the aforementioned EBG structure is also provided.
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公开(公告)号:US11940376B2
公开(公告)日:2024-03-26
申请号:US18147236
申请日:2022-12-28
Applicant: Anhui University of Science and Technology
Inventor: Huawei Jin , Fangzheng Yan , Lei Fang
CPC classification number: G01N21/1702 , G01N1/24 , G01N33/0027 , G01N2021/1704 , G01N2201/06113
Abstract: A system for detecting a concentration of free SiO2 in coal dust includes a first sampling tube and a second sampling tube for sampling the coal dust, a three-way control valve communicated with the first sampling tube and the second sampling tube respectively, a photoacoustic spectrometry detection device communicated with the three-way control valve through a connecting pipeline, and a SiO2 reaction tube for reacting SiO2 in the coal dust; and the SiO2 reaction tube is disposed on the second sampling tube. In the present disclosure, a coal dust sampling line is convenient to change by disposing the three-way control valve, and the first sampling tube and the second sampling tube are respectively communicated with the photoacoustic spectrometry detection device, so as to perform a differential accurate detection of the reacted CO content, and to obtain the SiO2 content.
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