公开(公告)号：US06740108B1

公开(公告)日：2004-05-25

申请号：US10115158

申请日：2002-04-03

申请人： Dale Just ,  Eric N. Rudie ,  Jonathan L. Flachman ,  Scott Stockmoe ,  Aaron Hjelle ,  Bruce W. Ebner ,  Joel Crabb ,  Stanley E. Kluge

发明人： Dale Just ,  Eric N. Rudie ,  Jonathan L. Flachman ,  Scott Stockmoe ,  Aaron Hjelle ,  Bruce W. Ebner ,  Joel Crabb ,  Stanley E. Kluge

IPC分类号： A61F700

CPC分类号： A61B18/18 ,  A61B18/1815 ,  A61B2017/00084 ,  A61B2017/00101 ,  A61B2017/00274 ,  A61B2018/00023 ,  A61B2018/00547

摘要： A thermal therapy catheter for preferentially treating tissue adjacent to a body lumen includes a catheter shaft that is insertable into the body lumen. An energy-emitting element is carried by the catheter shaft, and is operable to radiate a generally symmetrical energy pattern. The catheter shaft includes a plurality of cooling lumens around the energy-emitting element, configured for circulation of a fluid therethrough. An attenuating element is located in at least one of the plurality of cooling lumens and is arranged to modify the generally symmetrical energy pattern radiated by the energy-emitting element to deliver an asymmetrical energy pattern to the tissue adjacent to the body lumen.

摘要翻译： 用于优先处理邻近体腔的组织的热治疗导管包括可插入体腔内的导管轴。 能量发射元件由导管轴携带，并且可操作地辐射大致对称的能量图案。 导管轴包括围绕能量发射元件的多个冷却腔，其构造成用于使流体从其中循环流出。 衰减元件位于所述多个冷却腔中的至少一个中，并且被布置成修改由所述能量发射元件辐射的大致对称的能量图案，以向所述体腔附近的组织递送非对称能量图案。

公开(公告)号：US06496737B2

公开(公告)日：2002-12-17

申请号：US09733109

申请日：2000-12-08

申请人： Eric N. Rudie ,  Scott Stockmoe ,  Aaron Hjelle ,  Bruce W. Ebner ,  Joel Crabb ,  Jonathan L. Flachman ,  Stan Kluge ,  Satish Ramadhyani ,  Bruce Neilson

发明人： Eric N. Rudie ,  Scott Stockmoe ,  Aaron Hjelle ,  Bruce W. Ebner ,  Joel Crabb ,  Jonathan L. Flachman ,  Stan Kluge ,  Satish Ramadhyani ,  Bruce Neilson

IPC分类号： A61F200

CPC分类号： A61B18/1815 ,  A61B18/18 ,  A61B2017/00057 ,  A61B2017/00084 ,  A61B2017/00274 ,  A61B2017/22055 ,  A61B2018/00023 ,  A61B2018/00547

摘要： A thermal therapy catheter includes a catheter shaft having an outer surface that is insertable into the body lumen. The catheter shaft carries an energy-emitting element. A multi-lobe balloon is positioned around the outer surface of the catheter shaft adjacent to the energy-emitting element, with opposing ends of the multi-lobe balloon being sealingly connected to the catheter shaft to form a chamber between the multi-lobe balloon and the outer surface of the catheter shaft. Fluid is circulated between the outer surface of the catheter shaft and the multi-lobe balloon in a defined fluid flow path to firmly contact the wall of the body lumen and thereby cool the body lumen tissue while thermally treating targeted tissue at a depth from the body lumen wall.

摘要翻译： 热疗导管包括具有可插入体腔的外表面的导管轴。 导管轴带有能量发射元件。 多瓣球囊围绕导管轴的外表面定位在邻近能量发射元件的位置，多瓣球囊的相对端被密封地连接到导管轴上，以在多瓣球囊和 导管轴的外表面。 流体在导管轴的外表面和限定的流体流动路径中的多瓣球囊之间循环，以牢固地接触体腔壁，从而冷却体腔组织，同时在与身体深度相对的位置热处理靶组织 管腔壁。

公开(公告)号：US20080154349A1

公开(公告)日：2008-06-26

申请号：US12035194

申请日：2008-02-21

申请人： Martin A. Rossing ,  Stephen L. Bolea ,  David W. Mayer ,  Aaron Hjelle

发明人： Martin A. Rossing ,  Stephen L. Bolea ,  David W. Mayer ,  Aaron Hjelle

IPC分类号： A61N1/05

CPC分类号： A61N1/3752 ,  A61N1/05 ,  A61N1/0551 ,  A61N1/0558 ,  H01R4/14 ,  H01R4/4863 ,  H01R13/5224 ,  H01R13/5804 ,  H01R2201/12

摘要： Connection structures on an extra-vascular electrode lead body improve strain relief and strengthen the transition region where electrical conductors carried by the lead body are joined to individual electrodes at the distal end of the lead. The electrodes include structure or mechanisms for externally securing the electrode assembly to a body part. A first connection structure is located on the lead body proximal the electrodes to anchor the lead body to a first anchor location in the body that generally moves in concert with the body part. A second connection structure is located on the lead body proximal to the first connection structure to anchor the lead body to a second anchor location that is at least partially independent of movement of the body part. The first and second anchor location are offset by a distance that is less than a distance between the first and second connection structures to provide strain relief for the electrodes.

摘要翻译： 超血管电极引线体上的连接结构改善了应变消除，并且加强了由引线体承载的电导体连接到引线远端处的各个电极的过渡区域。 电极包括用于将电极组件外部固定到主体部分的结构或机构。 第一连接结构位于靠近电极的引线体上，以将引线主体锚固到主体中与身体部分一致移动的第一锚定位置。 第二连接结构位于靠近第一连接结构的引线体上，以将引线主体锚固到至少部分地与主体部分的运动无关的第二锚定位置。 第一和第二锚定位置偏移小于第一和第二连接结构之间的距离的距离，以为电极提供应变消除。

公开(公告)号：US20070276459A1

公开(公告)日：2007-11-29

申请号：US11836047

申请日：2007-08-08

申请人： Martin Rossing ,  Stephen Bolea ,  David Mayer ,  Aaron Hjelle ,  Tom Crowley ,  Eric Irwin

发明人： Martin Rossing ,  Stephen Bolea ,  David Mayer ,  Aaron Hjelle ,  Tom Crowley ,  Eric Irwin

IPC分类号： A61N1/04

CPC分类号： A61N1/3752 ,  A61N1/05 ,  A61N1/0551 ,  A61N1/0558 ,  H01R4/14 ,  H01R4/4863 ,  H01R13/5224 ,  H01R13/5804 ,  H01R2201/12

摘要： Connection structures on an extra-vascular electrode lead body improve strain relief and strengthen the transition region where electrical conductors carried by the lead body are joined to individual electrodes at the distal end of the lead. The electrodes include structure or mechanisms for externally securing the electrode assembly to a body part. A first connection structure is located on the lead body proximal the electrodes to anchor the lead body to a first anchor location in the body that generally moves in concert with the body part. A second connection structure is located on the lead body proximal to the first connection structure to anchor the lead body to a second anchor location that is at least partially independent of movement of the body part. The first and second anchor location are offset by a distance that is less than a distance between the first and second connection structures to provide strain relief for the electrodes.

摘要翻译： 超血管电极引线体上的连接结构改善了应变消除，并且加强了由引线体承载的电导体连接到引线远端处的各个电极的过渡区域。 电极包括用于将电极组件外部固定到主体部分的结构或机构。 第一连接结构位于靠近电极的引线体上，以将引线主体锚固到主体中与身体部分一致移动的第一锚定位置。 第二连接结构位于靠近第一连接结构的引线体上，以将引线主体锚固到至少部分地与主体部分的运动无关的第二锚定位置。 第一和第二锚定位置偏移小于第一和第二连接结构之间的距离的距离，以为电极提供应变消除。

公开(公告)号：US20060004420A1

公开(公告)日：2006-01-05

申请号：US11168238

申请日：2005-06-27

申请人： Martin Rossing ,  Stephen Bolea ,  Aaron Hjelle ,  James Henry ,  Brad Pedersen

发明人： Martin Rossing ,  Stephen Bolea ,  Aaron Hjelle ,  James Henry ,  Brad Pedersen

IPC分类号： A61N1/375

CPC分类号： A61N1/3752

摘要： A lockout connector arrangement for implantable medical devices having at least one port for receiving a non-cardiac lead connector selectively permits only certain electrical leads to be connected to the implantable medical device. A lead connector pin of a non-cardiac lead connector is specially designed to be larger than a DF-1 lead connector pin, but smaller than an IS-1 lead connector pin. A corresponding header of implantable pulse generator has a connector port for a non-cardiac lead with a proximal-most portion that is larger than the DF-1 lead connector pin, but smaller than the IS-1 lead connector pin; and otherwise generally consistent with the other dimensions of an ISO standard IS-1 pacemaker lead connector.

摘要翻译： 用于可植入医疗装置的锁定连接器装置具有用于接收非心脏引线连接器的至少一个端口，其选择性地仅允许某些电引线连接到可植入医疗装置。 非心脏引线连接器的引线连接器引脚专门设计为大于DF-1引脚连接器引脚，但小于IS-1引脚连接器引脚。 可植入脉冲发生器的相应标题具有用于非心脏引线的连接器端口，其最近部分大于DF-1引线连接器引脚，但小于IS-1引线连接器引脚; 否则大体上与ISO标准IS-1起搏器导线连接器的其他尺寸一致。

公开(公告)号：US6161049A

公开(公告)日：2000-12-12

申请号：US303259

申请日：1999-04-30

申请人： Eric N. Rudie ,  Scott Stockmoe ,  Aaron Hjelle ,  Bruce W. Ebner ,  Joel Crabb

发明人： Eric N. Rudie ,  Scott Stockmoe ,  Aaron Hjelle ,  Bruce W. Ebner ,  Joel Crabb

IPC分类号： A61B17/00 ,  A61B17/22 ,  A61B18/00 ,  A61B18/18 ,  A61F2/00

CPC分类号： A61B18/1815 ,  A61B18/18 ,  A61B2017/00057 ,  A61B2017/00084 ,  A61B2017/00274 ,  A61B2017/22055 ,  A61B2018/00023 ,  A61B2018/00547

摘要： A thermal therapy catheter includes a catheter shaft having an outer surface that is insertable into the body lumen. The catheter shaft carries an energy-emitting element. A multi-lobe balloon is positioned around the outer surface of the catheter shaft adjacent to the energy-emitting element, with opposing ends of the multi-lobe balloon being sealingly connected to the catheter shaft to form a chamber between the multi-lobe balloon and the outer surface of the catheter shaft. A fluid is circulated between the outer surface of the catheter shaft and the multi-lobe balloon in a defined fluid flow path to firmly contact the wall of the body lumen and thereby conductively cool the body lumen tissue while thermally treating targeted tissue at a depth from the body lumen wall.

摘要翻译： 热疗导管包括具有可插入体腔的外表面的导管轴。 导管轴带有能量发射元件。 多瓣球囊围绕导管轴的外表面定位在邻近能量发射元件的位置，多瓣球囊的相对端被密封地连接到导管轴上，以在多瓣球囊和 导管轴的外表面。 流体在导管轴的外表面和限定的流体流动路径中的多瓣球囊之间循环，以牢固地接触体腔的壁，从而导电地冷却身体腔组织，同时热处理来自 体腔内壁。

公开(公告)号：US07389149B2

公开(公告)日：2008-06-17

申请号：US11168753

申请日：2005-06-27

申请人： Martin A. Rossing ,  Stephen L. Bolea ,  David W. Mayer ,  Aaron Hjelle ,  Thomas P. Crowley ,  Eric D. Irwin

发明人： Martin A. Rossing ,  Stephen L. Bolea ,  David W. Mayer ,  Aaron Hjelle ,  Thomas P. Crowley ,  Eric D. Irwin

IPC分类号： A61N1/05

CPC分类号： A61N1/3752 ,  A61N1/05 ,  A61N1/0551 ,  A61N1/0558 ,  H01R4/14 ,  H01R4/4863 ,  H01R13/5224 ,  H01R13/5804 ,  H01R2201/12

摘要： Connection structures on an extra-vascular electrode lead body improve strain relief and strengthen the transition region where electrical conductors carried by the lead body are joined to individual electrodes at the distal end of the lead. The electrodes include structure or mechanisms for externally securing the electrode assembly to a body part. A first connection structure is located on the lead body proximal the electrodes to anchor the lead body to a first anchor location in the body that generally moves in concert with the body part. A second connection structure is located on the lead body proximal to the first connection structure to anchor the lead body to a second anchor location that is at least partially independent of movement of the body part. The first and second anchor location are offset by a distance that is less than a distance between the first and second connection structures to provide strain relief for the electrodes.

摘要翻译： 超血管电极引线体上的连接结构改善了应变消除，并且加强了由引线体承载的电导体连接到引线远端处的各个电极的过渡区域。 电极包括用于将电极组件外部固定到主体部分的结构或机构。 第一连接结构位于靠近电极的引线体上，以将引线主体锚固到主体中与身体部分一致移动的第一锚定位置。 第二连接结构位于靠近第一连接结构的引线体上，以将引线主体锚固到至少部分地与主体部分的运动无关的第二锚定位置。 第一和第二锚定位置偏移小于第一和第二连接结构之间的距离的距离，以为电极提供应变消除。

公开(公告)号：US20070282385A1

公开(公告)日：2007-12-06

申请号：US11836042

申请日：2007-08-08

申请人： Martin Rossing ,  Stephen Bolea ,  Aaron Hjelle ,  James Henry ,  Brad Pedersen

发明人： Martin Rossing ,  Stephen Bolea ,  Aaron Hjelle ,  James Henry ,  Brad Pedersen

IPC分类号： A61N1/02

CPC分类号： A61N1/3752

摘要： A lockout connector arrangement for implantable medical devices having at least one port for receiving a non-cardiac lead connector selectively permits only certain electrical leads to be connected to the implantable medical device. A lead connector pin of a non-cardiac lead connector is specially designed to be larger than a DF-1 lead connector pin, but smaller than an IS-1 lead connector pin. A corresponding header of implantable pulse generator has a connector port for a non-cardiac lead with a proximal-most portion that is larger than the DF-1 lead connector pin, but smaller than the IS-1 lead connector pin; and otherwise generally consistent with the other dimensions of an ISO standard IS-1 pacemaker lead connector.

摘要翻译： 用于可植入医疗装置的锁定连接器装置具有用于接收非心脏引线连接器的至少一个端口，其选择性地仅允许某些电引线连接到可植入医疗装置。 非心脏引线连接器的引线连接器引脚专门设计为大于DF-1引脚连接器引脚，但小于IS-1引脚连接器引脚。 可植入脉冲发生器的相应标题具有用于非心脏引线的连接器端口，其最近部分大于DF-1引线连接器引脚，但小于IS-1引线连接器引脚; 否则大体上与ISO标准IS-1起搏器导线连接器的其他尺寸一致。

公开(公告)号：US20060004430A1

公开(公告)日：2006-01-05

申请号：US11168753

申请日：2005-06-27

申请人： Martin Rossing ,  Stephen Bolea ,  David Mayer ,  Aaron Hjelle ,  Tom Crowley ,  Eric Irwin

发明人： Martin Rossing ,  Stephen Bolea ,  David Mayer ,  Aaron Hjelle ,  Tom Crowley ,  Eric Irwin

IPC分类号： A61N1/05

CPC分类号： A61N1/3752 ,  A61N1/05 ,  A61N1/0551 ,  A61N1/0558 ,  H01R4/14 ,  H01R4/4863 ,  H01R13/5224 ,  H01R13/5804 ,  H01R2201/12

摘要： Connection structures on an extra-vascular electrode lead body improve strain relief and strengthen the transition region where electrical conductors carried by the lead body are joined to individual electrodes at the distal end of the lead. The electrodes include structure or mechanisms for externally securing the electrode assembly to a body part. A first connection structure is located on the lead body proximal the electrodes to anchor the lead body to a first anchor location in the body that generally moves in concert with the body part. A second connection structure is located on the lead body proximal to the first connection structure to anchor the lead body to a second anchor location that is at least partially independent of movement of the body part. The first and second anchor location are offset by a distance that is less than a distance between the first and second connection structures to provide strain relief for the electrodes.

摘要翻译： 超血管电极引线体上的连接结构改善了应变消除，并且加强了由引线体承载的电导体连接到引线远端处的各个电极的过渡区域。 电极包括用于将电极组件外部固定到主体部分的结构或机构。 第一连接结构位于靠近电极的引线体上，以将引线主体锚固到主体中与身体部分一致移动的第一锚定位置。 第二连接结构位于靠近第一连接结构的引线体上，以将引线主体锚固到至少部分地与主体部分的运动无关的第二锚定位置。 第一和第二锚定位置偏移小于第一和第二连接结构之间的距离的距离，以为电极提供应变消除。

公开(公告)号：US08014874B2

公开(公告)日：2011-09-06

申请号：US11836047

申请日：2007-08-08

申请人： Martin A. Rossing ,  Stephen L. Bolea ,  David W. Mayer ,  Aaron Hjelle ,  Thomas P. Crowley ,  Eric D. Irwin

发明人： Martin A. Rossing ,  Stephen L. Bolea ,  David W. Mayer ,  Aaron Hjelle ,  Thomas P. Crowley ,  Eric D. Irwin

IPC分类号： A61N1/05

CPC分类号： A61N1/3752 ,  A61N1/05 ,  A61N1/0551 ,  A61N1/0558 ,  H01R4/14 ,  H01R4/4863 ,  H01R13/5224 ,  H01R13/5804 ,  H01R2201/12

摘要： Connection structures on an extra-vascular electrode lead body improve strain relief and strengthen the transition region where electrical conductors carried by the lead body are joined to individual electrodes at the distal end of the lead. The electrodes include structure or mechanisms for externally securing the electrode assembly to a body part. A first connection structure is located on the lead body proximal the electrodes to anchor the lead body to a first anchor location in the body that generally moves in concert with the body part. A second connection structure is located on the lead body proximal to the first connection structure to anchor the lead body to a second anchor location that is at least partially independent of movement of the body part. The first and second anchor location are offset by a distance that is less than a distance between the first and second connection structures to provide strain relief for the electrodes.

摘要翻译： 超血管电极引线体上的连接结构改善了应变消除，并且加强了由引线体承载的电导体连接到引线远端处的各个电极的过渡区域。 电极包括用于将电极组件外部固定到主体部分的结构或机构。 第一连接结构位于靠近电极的引线体上，以将引线主体锚固到主体中与身体部分一致移动的第一锚定位置。 第二连接结构位于靠近第一连接结构的引线体上，以将引线主体锚固到至少部分地与主体部分的运动无关的第二锚定位置。 第一和第二锚定位置偏移小于第一和第二连接结构之间的距离的距离，以为电极提供应变消除。