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    Compounds that bind to p185 and methods of using the same
    3.
    发明授权
    Compounds that bind to p185 and methods of using the same 有权
    结合p185的化合物及其使用方法

    公开(公告)号：US07179785B2

    公开(公告)日：2007-02-20

    申请号：US10301499

    申请日：2002-11-21

    Applicant: Mark I. Greene ,  Ramachandran Murali ,  Alan Berezov

    Inventor： Mark I. Greene ,  Ramachandran Murali ,  Alan Berezov

    IPC: A61K38/00

    CPC classification number: C07K16/32 ,  A61K2039/505 ,  C07K2317/565

    Abstract: Novels peptides and pharmaceutical compositions comprising the same are disclosed. Conjugated compositions peptides linked to detectable agents and/or cytotoxic agents. are disclosed. Method of detecting tumors that have p185 on tumor cell surfaces are disclosed. Methods of preventing transformation of a normal cell into a tumor cell in an individual at risk of developing a tumor having tumor cells which have p185 on their surfaces are disclosed. Methods of treating an individual who has cancer characterized by tumor cells that have a p185 on their cell surfaces are disclosed.

    Abstract translation: 公开了新颖的肽和包含其的药物组合物。 与可检测的试剂和/或细胞毒性剂连接的共轭组合物肽。 被披露。 公开了检测肿瘤细胞表面上具有p185的肿瘤的方法。 公开了防止正常细胞转化成具有在其表面具有p185的肿瘤细胞的肿瘤的风险中的个体的肿瘤细胞的方法。 公开了在细胞表面处理具有p185的肿瘤细胞特征的癌症的个体的方法。

    TIP60 INHIBITORS
    4.
    发明申请
    TIP60 INHIBITORS 有权
    TIP60抑制剂

    公开(公告)号：US20140187579A1

    公开(公告)日：2014-07-03

    申请号：US13991192

    申请日：2011-12-02

    Applicant: Mark I Greene ,  Alan Berezov ,  Yan Xiao ,  Hongtao Zhang

    Inventor： Mark I Greene ,  Alan Berezov ,  Yan Xiao ,  Hongtao Zhang

    IPC: C07D207/277 ,  C07D401/12

    CPC classification number: C07D207/277 ,  A61K31/4015 ,  A61K31/4709 ,  C07D401/12

    Abstract: This invention is in the fields of immunology and autoimmunity. More particularly it concerns pharmaceutical compositions comprising compounds which are useful agents for inhibiting the functions of TIP60 and the use of such compounds in the treatment of an individual suffering, for example, from ulcerative colitis and other irritable bowel diseases.

    Abstract translation: 本发明在免疫学和自身免疫领域。 更具体地，涉及包含作为抑制TIP60的功能的有用试剂的化合物的药物组合物，以及这些化合物在治疗患有例如溃疡性结肠炎和其它肠易激惹的疾病的个体中的用途。

    Compounds that bind to p185 and methods of using the same
    5.
    发明授权
    Compounds that bind to p185 and methods of using the same 有权
    结合p185的化合物及其使用方法

    公开(公告)号：US07998924B2

    公开(公告)日：2011-08-16

    申请号：US12758435

    申请日：2010-04-12

    Applicant: Mark I. Greene ,  Ramachandran Murali ,  Alan Berezov

    Inventor： Mark I. Greene ,  Ramachandran Murali ,  Alan Berezov

    IPC: A61K38/00 ,  A61K38/04 ,  A61K51/00 ,  C07K5/00 ,  C07K7/00 ,  C07K16/00 ,  C07K17/00

    CPC classification number: C07K16/32 ,  A61K2039/505 ,  C07K2317/565

    Abstract: Novel peptides and pharmaceutical compositions comprising the same are disclosed. Conjugated compositions peptides linked to detectable agents and/or cytotoxic agents are disclosed. Method of detecting tumors that have p185 on tumor cell surfaces are disclosed. Methods of preventing transformation of a normal cell into a tumor cell in an individual at risk of developing a tumor having tumor cells which have p185 on their surfaces are disclosed. Methods of treating an individual who has cancer characterized by tumor cells that have a p185 on their cell surfaces are disclosed.

    Abstract translation: 公开了包含其的新型肽和药物组合物。 公开了与可检测的试剂和/或细胞毒性剂连接的共轭组合物肽。 公开了检测肿瘤细胞表面上具有p185的肿瘤的方法。 公开了防止正常细胞转化成具有在其表面具有p185的肿瘤细胞的肿瘤的风险中的个体的肿瘤细胞的方法。 公开了在细胞表面处理具有p185的肿瘤细胞特征的癌症的个体的方法。

    Control system for a cloth spreading machine
    6.
    发明授权
    Control system for a cloth spreading machine 失效
    布布机控制系统

    公开(公告)号：US5826868A

    公开(公告)日：1998-10-27

    申请号：US578036

    申请日：1995-12-26

    Applicant: Michael Dale Russell ,  David Alan Berezov ,  Jiakun Wu

    Inventor： Michael Dale Russell ,  David Alan Berezov ,  Jiakun Wu

    IPC: B65H16/02 ,  B65H45/103 ,  B65H29/46

    CPC classification number: B65H16/028 ,  B65H16/005 ,  B65H45/103 ,  B65H2301/41374 ,  B65H2513/10

    Abstract: A control system for a material spreading machine pre-determines a machine velocity trajectory plan so that the velocity and acceleration of the machine down the spreading table can be controlled in real time. The control system includes encoders which provide real time information as to the actual machine velocity and material feed rate so that dynamic feedback and control of the spread can be maintained. Data from the machine velocity encoder is used to calculate the actual position of the machine along the table during the spread.

    Abstract translation: 用于材料分散机的控制系统预先确定机器速度轨迹计划，使得能够实时地控制机器在扩展台下的速度和加速度。 控制系统包括编码器，其提供关于实际机器速度和材料进给速率的实时信息，从而可以维持传播的动态反馈和控制。 机器速度编码器的数据用于在扩展期间计算机床沿台面的实际位置。

    Compounds that bind to P185 and methods of using the same
    10.
    发明申请
    Compounds that bind to P185 and methods of using the same 有权
    与P185结合的化合物及其使用方法

    公开(公告)号：US20070207086A1

    公开(公告)日：2007-09-06

    申请号：US11283474

    申请日：2005-11-17

    Applicant: Mark Greene ,  Ramachandran Murali ,  Alan Berezov

    Inventor： Mark Greene ,  Ramachandran Murali ,  Alan Berezov

    IPC: A61K38/12 ,  A61K51/08 ,  C07K7/64

    CPC classification number: C07K16/32 ,  A61K2039/505 ,  C07K2317/565

    Abstract: Novel peptides and pharmaceutical compositions comprising the same are disclosed. Conjugated compositions peptides linked to detectable agents and/or cytotoxic agents. are disclosed. Method of detecting tumors that have p185 on tumor cell surfaces are disclosed. Methods of preventing transformation of a normal cell into a tumor cell in an individual at risk of developing a tumor having tumor cells which have p185 on their surfaces are disclosed. Methods of treating an individual who has cancer characterized by tumor cells that have a p185 on their cell surfaces are disclosed.

    Abstract translation: 公开了包含其的新型肽和药物组合物。 与可检测的试剂和/或细胞毒性剂连接的共轭组合物肽。 被披露。 公开了检测肿瘤细胞表面上具有p185的肿瘤的方法。 公开了防止正常细胞转化成患有肿瘤细胞的肿瘤细胞的方法，所述肿瘤细胞具有在其表面具有p185的肿瘤细胞的肿瘤的风险。 公开了在细胞表面处理具有p185的肿瘤细胞特征的癌症的个体的方法。

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