公开(公告)号：US20150076343A1

公开(公告)日：2015-03-19

申请号：US14528917

申请日：2014-10-30

申请人： Aleksey Tolmachev ,  Richard D. Smith ,  Yehia M. Ibrahim ,  Gordon A. Anderson ,  Erin M. Baker

发明人： Aleksey Tolmachev ,  Richard D. Smith ,  Yehia M. Ibrahim ,  Gordon A. Anderson ,  Erin M. Baker

IPC分类号： H01J49/06

CPC分类号： H01J49/062 ,  G01N27/622 ,  H01J49/06

摘要： An ion manipulation method and device to prevent loss of ions is disclosed. The device includes a pair of surfaces. An inner array of electrodes is coupled to the surfaces. A RF voltage and a DC voltage are alternately applied to the inner array of electrodes. The applied RF voltage is alternately positive and negative so that immediately adjacent or nearest neighbor RF applied electrodes are supplied with RF signals that are approximately 180 degrees out of phase.

摘要翻译： 公开了一种用于防止离子损失的离子操作方法和装置。 该装置包括一对表面。 电极的内部阵列耦合到表面。 RF电压和DC电压交替施加到电极的内部阵列。 施加的RF电压交替地是正的和负的，使得紧邻或最近邻RF施加的电极被提供有大约相差180度的RF信号。

公开(公告)号：US06608302B2

公开(公告)日：2003-08-19

申请号：US09870577

申请日：2001-05-30

申请人： Richard D. Smith ,  Christophe D. Masselon ,  Aleksey Tolmachev

发明人： Richard D. Smith ,  Christophe D. Masselon ,  Aleksey Tolmachev

IPC分类号： H01J4900

CPC分类号： H01J49/0009 ,  H01J49/38

摘要： A method for improving the calibration of a Fourier transform ion cyclotron resonance mass spectrometer wherein the frequency spectrum of a sample has been measured and the frequency (f) and intensity (I) of at least three species having known mass to charge (m/z) ratios and one specie having an unknown (m/z) ratio have been identified. The method uses the known (m/z) ratios, frequencies, and intensities at least three species to calculate coefficients A, B, and C, wherein the mass to charge ratio of a least one of the three species (m/z)i is equal to A f i + B f i 2 + C · G ⁡ ( I i ) f i Q wherein fi is the detected frequency of the specie, G(Ii) is a predetermined function of the intensity of the species, and Q is a predetermined exponent. Using the calculated values for A, B, and C, the mass to charge ratio of the unknown specie (m/z)ii is calculated as the sum of A f ii + B f ii 2 + C · G ⁡ ( I ii ) f ii Q wherein fii is the measured frequency of the unknown specie, and (Iii) is the measured intensity of the unknown specie.

摘要翻译： 一种用于改进傅里叶变换离子回旋共振质谱仪的校准的方法，其中已经测量了样品的频谱，以及已知质量电荷的至少三种物质的频率（f）和强度（I）（m / z ）比例，并且已经鉴定了具有未知（m / z）比的一种物质。 该方法使用至少三种物质的已知（m / z）比，频率和强度来计算系数A，B和C，其中三种物质（m / z）i中的至少一种的质荷比 等于其中fi是物种的检测频率，G（Ii）是物种强度的预定函数，Q是预定指数。 使用A，B和C的计算值，将未知物种（m / z）ii的质荷比计算为fii是未知物种的测量频率的总和，（Iii）是测量的 未知物种的强度。

公开(公告)号：US08969800B1

公开(公告)日：2015-03-03

申请号：US14528917

申请日：2014-10-30

申请人： Aleksey Tolmachev ,  Richard D. Smith ,  Yehia M. Ibrahim ,  Gordon A. Anderson ,  Erin M. Baker

发明人： Aleksey Tolmachev ,  Richard D. Smith ,  Yehia M. Ibrahim ,  Gordon A. Anderson ,  Erin M. Baker

IPC分类号： H01J49/26

CPC分类号： H01J49/062 ,  G01N27/622 ,  H01J49/06

摘要： An ion manipulation method and device to prevent loss of ions is disclosed. The device includes a pair of surfaces. An inner array of electrodes is coupled to the surfaces. A RF voltage and a DC voltage are alternately applied to the inner array of electrodes. The applied RF voltage is alternately positive and negative so that immediately adjacent or nearest neighbor RF applied electrodes are supplied with RF signals that are approximately 180 degrees out of phase.

摘要翻译： 公开了一种用于防止离子损失的离子操作方法和装置。 该装置包括一对表面。 电极的内部阵列耦合到表面。 RF电压和DC电压交替施加到电极的内部阵列。 施加的RF电压交替地是正的和负的，使得紧邻或最近邻RF施加的电极被提供有大约相差180度的RF信号。