公开(公告)号：US20110200568A1

公开(公告)日：2011-08-18

申请号：US13058154

申请日：2009-08-10

申请人： Yasuhiro Ikeda ,  Andre Terzic ,  Timothy J. Nelson ,  Amber A. Mael ,  Almudena J. Martinez Fernandez ,  Satsuki Yamada

发明人： Yasuhiro Ikeda ,  Andre Terzic ,  Timothy J. Nelson ,  Amber A. Mael ,  Almudena J. Martinez Fernandez ,  Satsuki Yamada

IPC分类号： A61K35/12 ,  C12N5/10 ,  C12N5/071 ,  A61P9/00

CPC分类号： C12N5/0696 ,  A61K35/12 ,  C12N2500/90 ,  C12N2500/98 ,  C12N2501/602 ,  C12N2501/603 ,  C12N2501/604 ,  C12N2501/605 ,  C12N2501/606 ,  C12N2501/608 ,  C12N2510/00 ,  C12N2740/16043

摘要： This document provides methods and materials related to induced pluripotent stem cells. For example, induced pluripotent stem cells, compositions containing induced pluripotent stem cells, methods for obtaining induced pluripotent stem cells, and methods for using induced pluripotent stem cells are provided. In addition, methods and materials for using induced pluripotent stem cells to repair tissue (e.g., cardiovascular tissue) in vivo as well as methods and materials for using induced pluripotent stem cells to assess their therapeutic potential in appropriate animal models are provided.

摘要翻译： 本文提供了与诱导多能干细胞相关的方法和材料。 例如，提供诱导多能干细胞，含有诱导多能干细胞的组合物，获得诱导多能干细胞的方法，以及使用诱导性多能干细胞的方法。 此外，提供了使用诱导性多能干细胞修复体内组织（例如心血管组织）的方法和材料以及用于使用诱导性多能干细胞评价其在适当动物模型中的治疗潜力的方法和材料。

公开(公告)号：US10047346B2

公开(公告)日：2018-08-14

申请号：US13058154

申请日：2009-08-10

申请人： Yasuhiro Ikeda ,  Andre Terzic ,  Timothy J. Nelson ,  Amber A. Mael ,  Almudena J. Martinez Fernandez ,  Satsuki Yamada

发明人： Yasuhiro Ikeda ,  Andre Terzic ,  Timothy J. Nelson ,  Amber A. Mael ,  Almudena J. Martinez Fernandez ,  Satsuki Yamada

IPC分类号： A01N63/00 ,  A61K48/00 ,  C12N5/074 ,  A61K35/12

摘要： This document provides methods and materials related to induced pluripotent stem cells. For example, induced pluripotent stem cells, compositions containing induced pluripotent stem cells, methods for obtaining induced pluripotent stem cells, and methods for using induced pluripotent stem cells are provided. In addition, methods and materials for using induced pluripotent stem cells to repair tissue (e.g., cardiovascular tissue) in vivo as well as methods and materials for using induced pluripotent stem cells to assess their therapeutic potential in appropriate animal models are provided.